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The map label for this gene is gmuR [H]

Identifier: 152969405

GI number: 152969405

Start: 945164

End: 945898

Strand: Direct

Name: gmuR [H]

Synonym: KPN_00848

Alternate gene names: 152969405

Gene position: 945164-945898 (Clockwise)

Preceding gene: 152969404

Following gene: 152969408

Centisome position: 17.78

GC content: 58.37

Gene sequence:

>735_bases
ATGGATAAGGACCGGGAAATGACGGCGAAGTATCTGCAAATCGCGCGGGAAATAAAAAAACGCATCATCAGCCAGCAGTA
TCCTGCCAGCGCGCCGCTACCCGACCAGTTTGCGCTGGCGGCGGAGTTCAGCACCAGCCGGATGACCATCCAGCAGGCGA
TGCGCCAGTTAATCGTCGAAGGGCTGATCTATACCCGAAAAGGGCAGGGCACCTTTGTGCGGAAAAATTTCCTTCAGCTG
TCGCAGTGGGAGCTGCCCGGCAGCGACTATTTCGGCGCCACCAAAACCTGGGAGCATCTTGGCGAGGTGCAAAGCGAAGT
GGTGCGCTTTGCGGTGCGCTTTCCCAGCGACAAGGAGCAAAGTTCGCTGCTTATCGACGCCGATGCCCCGGTGTATGACT
TTGTTCGCCTGCGGCTGCTCAACGGCGAGCCGGTATCCCTGGATCTGACGGTCATGCCGGTGGGGCTGGTGCCGGGGTTA
ACCAAAAGCCATCTGGAAGGTTCCGTGTTTCGCTATGTGCAGGAGACGCTGGGGCTGAAGCTGATGGGATCTTACCGCGT
GGTGCGGGCGATGAAGCCCGGGGAACTGGATAAACAGCATCTTCACTGCGAACCGACCGATCCGGTGCTGGAGGTGGAGC
AGGTTATCTATCTGGAGGATGGCACGCCGCTGGAGTACGCCCACTGCCATTATCGCTACGATCACGGCGGGATTATTCTG
GTGAATAACGGCTAG

Upstream 100 bases:

>100_bases
GCTATGCATGGCTGAAGCAGGTGTTCCGCAGCAACGGCGAAGCGATGTAACGCTGCCCTGGCGGTCAGATGGTGTATCCA
GCCCGCCAGCCACTCACTGA

Downstream 100 bases:

>100_bases
GCCGGGGCTCCTGCTGGCGCTGCGCATAGCGGGGTTACGGCGTGGTAGGGTTTGGTAGCCCGGGCGAGCGTTAGCCGCCT
CGAGGGAAAATGCCGATAAA

Product: putative transcriptional regulator

Products: NA

Alternate protein names: Glucomannan utilization operon repressor; Glucomannan utilization protein R [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MDKDREMTAKYLQIAREIKKRIISQQYPASAPLPDQFALAAEFSTSRMTIQQAMRQLIVEGLIYTRKGQGTFVRKNFLQL
SQWELPGSDYFGATKTWEHLGEVQSEVVRFAVRFPSDKEQSSLLIDADAPVYDFVRLRLLNGEPVSLDLTVMPVGLVPGL
TKSHLEGSVFRYVQETLGLKLMGSYRVVRAMKPGELDKQHLHCEPTDPVLEVEQVIYLEDGTPLEYAHCHYRYDHGGIIL
VNNG

Sequences:

>Translated_244_residues
MDKDREMTAKYLQIAREIKKRIISQQYPASAPLPDQFALAAEFSTSRMTIQQAMRQLIVEGLIYTRKGQGTFVRKNFLQL
SQWELPGSDYFGATKTWEHLGEVQSEVVRFAVRFPSDKEQSSLLIDADAPVYDFVRLRLLNGEPVSLDLTVMPVGLVPGL
TKSHLEGSVFRYVQETLGLKLMGSYRVVRAMKPGELDKQHLHCEPTDPVLEVEQVIYLEDGTPLEYAHCHYRYDHGGIIL
VNNG
>Mature_244_residues
MDKDREMTAKYLQIAREIKKRIISQQYPASAPLPDQFALAAEFSTSRMTIQQAMRQLIVEGLIYTRKGQGTFVRKNFLQL
SQWELPGSDYFGATKTWEHLGEVQSEVVRFAVRFPSDKEQSSLLIDADAPVYDFVRLRLLNGEPVSLDLTVMPVGLVPGL
TKSHLEGSVFRYVQETLGLKLMGSYRVVRAMKPGELDKQHLHCEPTDPVLEVEQVIYLEDGTPLEYAHCHYRYDHGGIIL
VNNG

Specific function: Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790118, Length=219, Percent_Identity=30.1369863013699, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1786950, Length=231, Percent_Identity=29.004329004329, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082252, Length=217, Percent_Identity=20.7373271889401, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27730; Mature: 27730

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKDREMTAKYLQIAREIKKRIISQQYPASAPLPDQFALAAEFSTSRMTIQQAMRQLIVE
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEECCCHHHHHHHHHHHHHHHH
GLIYTRKGQGTFVRKNFLQLSQWELPGSDYFGATKTWEHLGEVQSEVVRFAVRFPSDKEQ
HHHEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
SSLLIDADAPVYDFVRLRLLNGEPVSLDLTVMPVGLVPGLTKSHLEGSVFRYVQETLGLK
CCEEEECCCCHHHHHEEEEECCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCEE
LMGSYRVVRAMKPGELDKQHLHCEPTDPVLEVEQVIYLEDGTPLEYAHCHYRYDHGGIIL
EECCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCEEEEEEEECCCCEEE
VNNG
EECC
>Mature Secondary Structure
MDKDREMTAKYLQIAREIKKRIISQQYPASAPLPDQFALAAEFSTSRMTIQQAMRQLIVE
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEECCCHHHHHHHHHHHHHHHH
GLIYTRKGQGTFVRKNFLQLSQWELPGSDYFGATKTWEHLGEVQSEVVRFAVRFPSDKEQ
HHHEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
SSLLIDADAPVYDFVRLRLLNGEPVSLDLTVMPVGLVPGLTKSHLEGSVFRYVQETLGLK
CCEEEECCCCHHHHHEEEEECCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCEE
LMGSYRVVRAMKPGELDKQHLHCEPTDPVLEVEQVIYLEDGTPLEYAHCHYRYDHGGIIL
EECCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCEEEEEEEECCCCEEE
VNNG
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]