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The map label for this gene is bglA [H]

Identifier: 152969404

GI number: 152969404

Start: 943788

End: 945113

Strand: Direct

Name: bglA [H]

Synonym: KPN_00847

Alternate gene names: 152969404

Gene position: 943788-945113 (Clockwise)

Preceding gene: 152969403

Following gene: 152969405

Centisome position: 17.76

GC content: 55.81

Gene sequence:

>1326_bases
ATGCAGACGGAGGGGGCGTGGAACGAGGGTGGCAAGGGGATGTCGGTGTATGATATCCGTCAACCGGCGGAGTTCGCCTC
CGACTGGAAGGTGGCGACCGACTCTTATCATCGTTATCGGGAAGATTTCGATTTGATGCAGGATCTGGGCATGAACTGCT
ACCGTTTTCAGATCGCCTGGAGCCGGGTGTGCCCTGACGGAGATGGCGAATTCAATGAACAGGGGATTGCCTTCTACCAT
CAATTTATAGATGAACTGATCGCCCGCGGCATTGAGCCGATGATCTGCCTGTACCACTTCGATATGCCGCTGTCGCTGGC
GGAGCGCTACAACGGTTTTACCGACCGCCGGGTGATGGACGCTTTTATCCGCTACGGCCAGAAGATGATCGCCTGCTATG
GCGACAAGGTGAAATATTGGCTCACCTTTAATGAGCAGAATCTGTACCATTCGCCGGAAGCGTTTCTGATTTCCGGCTAT
CTGCAGGGGGAGAAGACCCTGCGCGAACTGTATCTGATCCAGCATCATGTGATGATGGCGCACGTCCATCTGACTCACTA
TCTGCACCAGACGAAGCCGCAGTGTCTGATGGGCGGAATGCTGGCTCACGCTCTGGTCTATCCGGCTACCTGCAAACCAC
GCGATATCCTCTGCGCCCAGCAGCTGGATGAGTTCTTAAACCAGAACCTGCTGCGCGCCTACGCGGGTGAGGGTTATAGC
CCGGAGGTGATGCATTTTGTCGCCGCGGAAGGGTTCGATGATATCTATCGGCGGGAGGATCTCGCCCTGATGGCGACGGT
GAAGGTCGATTATCTGGCGTTCAGCTATTACGCCAGCCGCACATTGAACAGCGACGCGATCCCGCCGGGAACGGCGGTCA
ACAACTATATGCTGTTTGGCAACCAGGATAACCCGTTCCTGAAAGCGACGGAATGGAACTGGCAGATTGATCCGCTGGGC
TTCCGGACGATCATCACTCGTTACTATAACGATTGGCGCCTGCCGGTGTTCCCGATTGAAAACGGCATCGGGGTGATTGA
GTCCTGGGACGGCGAACATCCCATTGCCGATGATTACCGCATCGCTTACCATCGCGACCATATCAACGCCATGAAAGCGG
CCATCTTTGAGGATGGGGCGCAGGTGATCGGCTATCTCGGCTGGGGATTAATCGATATCCTGAGCTCACAGGGCGATATG
CGTAAGCGCTACGGCGTGGTGTACGTCAATCGCGAAAACCATGACCTCAAGGACCTGCGGCGGGTGCCGAAGAAGAGCTA
TGCATGGCTGAAGCAGGTGTTCCGCAGCAACGGCGAAGCGATGTAA

Upstream 100 bases:

>100_bases
TATGACTAGTCATTACGTTTAAATGACTAGTCATATACCGAGGCGCAGCATGAAGAACAGACTACCGGCAGATTTTTTAT
GGGGAAATTCCGTCTCCAGC

Downstream 100 bases:

>100_bases
CGCTGCCCTGGCGGTCAGATGGTGTATCCAGCCCGCCAGCCACTCACTGAATGGATAAGGACCGGGAAATGACGGCGAAG
TATCTGCAAATCGCGCGGGA

Product: glycoside hydrolase family protein 1

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MQTEGAWNEGGKGMSVYDIRQPAEFASDWKVATDSYHRYREDFDLMQDLGMNCYRFQIAWSRVCPDGDGEFNEQGIAFYH
QFIDELIARGIEPMICLYHFDMPLSLAERYNGFTDRRVMDAFIRYGQKMIACYGDKVKYWLTFNEQNLYHSPEAFLISGY
LQGEKTLRELYLIQHHVMMAHVHLTHYLHQTKPQCLMGGMLAHALVYPATCKPRDILCAQQLDEFLNQNLLRAYAGEGYS
PEVMHFVAAEGFDDIYRREDLALMATVKVDYLAFSYYASRTLNSDAIPPGTAVNNYMLFGNQDNPFLKATEWNWQIDPLG
FRTIITRYYNDWRLPVFPIENGIGVIESWDGEHPIADDYRIAYHRDHINAMKAAIFEDGAQVIGYLGWGLIDILSSQGDM
RKRYGVVYVNRENHDLKDLRRVPKKSYAWLKQVFRSNGEAM

Sequences:

>Translated_441_residues
MQTEGAWNEGGKGMSVYDIRQPAEFASDWKVATDSYHRYREDFDLMQDLGMNCYRFQIAWSRVCPDGDGEFNEQGIAFYH
QFIDELIARGIEPMICLYHFDMPLSLAERYNGFTDRRVMDAFIRYGQKMIACYGDKVKYWLTFNEQNLYHSPEAFLISGY
LQGEKTLRELYLIQHHVMMAHVHLTHYLHQTKPQCLMGGMLAHALVYPATCKPRDILCAQQLDEFLNQNLLRAYAGEGYS
PEVMHFVAAEGFDDIYRREDLALMATVKVDYLAFSYYASRTLNSDAIPPGTAVNNYMLFGNQDNPFLKATEWNWQIDPLG
FRTIITRYYNDWRLPVFPIENGIGVIESWDGEHPIADDYRIAYHRDHINAMKAAIFEDGAQVIGYLGWGLIDILSSQGDM
RKRYGVVYVNRENHDLKDLRRVPKKSYAWLKQVFRSNGEAM
>Mature_441_residues
MQTEGAWNEGGKGMSVYDIRQPAEFASDWKVATDSYHRYREDFDLMQDLGMNCYRFQIAWSRVCPDGDGEFNEQGIAFYH
QFIDELIARGIEPMICLYHFDMPLSLAERYNGFTDRRVMDAFIRYGQKMIACYGDKVKYWLTFNEQNLYHSPEAFLISGY
LQGEKTLRELYLIQHHVMMAHVHLTHYLHQTKPQCLMGGMLAHALVYPATCKPRDILCAQQLDEFLNQNLLRAYAGEGYS
PEVMHFVAAEGFDDIYRREDLALMATVKVDYLAFSYYASRTLNSDAIPPGTAVNNYMLFGNQDNPFLKATEWNWQIDPLG
FRTIITRYYNDWRLPVFPIENGIGVIESWDGEHPIADDYRIAYHRDHINAMKAAIFEDGAQVIGYLGWGLIDILSSQGDM
RKRYGVVYVNRENHDLKDLRRVPKKSYAWLKQVFRSNGEAM

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=471, Percent_Identity=27.8131634819533, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI110681710, Length=472, Percent_Identity=29.0254237288136, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI28376633, Length=455, Percent_Identity=27.6923076923077, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI13273313, Length=458, Percent_Identity=26.4192139737991, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI24497614, Length=469, Percent_Identity=26.4392324093817, Blast_Score=126, Evalue=5e-29,
Organism=Escherichia coli, GI2367174, Length=463, Percent_Identity=36.0691144708423, Blast_Score=294, Evalue=8e-81,
Organism=Escherichia coli, GI1789070, Length=468, Percent_Identity=36.3247863247863, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI2367270, Length=453, Percent_Identity=36.644591611479, Blast_Score=283, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI17539390, Length=460, Percent_Identity=27.1739130434783, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17552856, Length=457, Percent_Identity=28.0087527352298, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI21356577, Length=470, Percent_Identity=24.468085106383, Blast_Score=132, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 51265; Mature: 51265

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTEGAWNEGGKGMSVYDIRQPAEFASDWKVATDSYHRYREDFDLMQDLGMNCYRFQIAW
CCCCCCCCCCCCCCEEEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEH
SRVCPDGDGEFNEQGIAFYHQFIDELIARGIEPMICLYHFDMPLSLAERYNGFTDRRVMD
HHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHCCCCCHHHHHH
AFIRYGQKMIACYGDKVKYWLTFNEQNLYHSPEAFLISGYLQGEKTLRELYLIQHHVMMA
HHHHHCHHEEEEECCCEEEEEEECCCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHHHHHH
HVHLTHYLHQTKPQCLMGGMLAHALVYPATCKPRDILCAQQLDEFLNQNLLRAYAGEGYS
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PEVMHFVAAEGFDDIYRREDLALMATVKVDYLAFSYYASRTLNSDAIPPGTAVNNYMLFG
HHHHHHHHHCCHHHHHHCCCEEEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEC
NQDNPFLKATEWNWQIDPLGFRTIITRYYNDWRLPVFPIENGIGVIESWDGEHPIADDYR
CCCCCEEEEECCCEEECCCHHHHHHHHHHCCCCCEEEECCCCCCEEECCCCCCCCCCCEE
IAYHRDHINAMKAAIFEDGAQVIGYLGWGLIDILSSQGDMRKRYGVVYVNRENHDLKDLR
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCEEEEECCCCCHHHHH
RVPKKSYAWLKQVFRSNGEAM
HCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQTEGAWNEGGKGMSVYDIRQPAEFASDWKVATDSYHRYREDFDLMQDLGMNCYRFQIAW
CCCCCCCCCCCCCCEEEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEH
SRVCPDGDGEFNEQGIAFYHQFIDELIARGIEPMICLYHFDMPLSLAERYNGFTDRRVMD
HHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHCCCCCHHHHHH
AFIRYGQKMIACYGDKVKYWLTFNEQNLYHSPEAFLISGYLQGEKTLRELYLIQHHVMMA
HHHHHCHHEEEEECCCEEEEEEECCCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHHHHHH
HVHLTHYLHQTKPQCLMGGMLAHALVYPATCKPRDILCAQQLDEFLNQNLLRAYAGEGYS
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PEVMHFVAAEGFDDIYRREDLALMATVKVDYLAFSYYASRTLNSDAIPPGTAVNNYMLFG
HHHHHHHHHCCHHHHHHCCCEEEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEC
NQDNPFLKATEWNWQIDPLGFRTIITRYYNDWRLPVFPIENGIGVIESWDGEHPIADDYR
CCCCCEEEEECCCEEECCCHHHHHHHHHHCCCCCEEEECCCCCCEEECCCCCCCCCCCEE
IAYHRDHINAMKAAIFEDGAQVIGYLGWGLIDILSSQGDMRKRYGVVYVNRENHDLKDLR
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCEEEEECCCCCHHHHH
RVPKKSYAWLKQVFRSNGEAM
HCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8125345; 9384377 [H]