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The map label for this gene is nagA [H]

Identifier: 150398599

GI number: 150398599

Start: 3617383

End: 3618543

Strand: Direct

Name: nagA [H]

Synonym: Smed_3410

Alternate gene names: 150398599

Gene position: 3617383-3618543 (Clockwise)

Preceding gene: 150398598

Following gene: 150398603

Centisome position: 95.65

GC content: 65.55

Gene sequence:

>1161_bases
ATGAACGGGAACAAGACGATCACCGGAGCACGGGTTTTCGACGGCATCGACTGGCACGACGGCGCCGCCCTCGTGGTCGA
GTCAGGGCACGTGAAGTCGATTGTGCCGGCGGGGAGCGTAGCCGTCGGTGGCGAGACCGTCGACGCCCATGGCCTGCTTC
TCGTACCCGGCTTCATCGATCTTCAGGTGAATGGCGGCGGCGGCGCACTCCTGAACGAAGAACCTACCCTCGCAGGCATC
CGGCAGATCTGCTCGGCGCATGCGACATTCGGTACGACGGCGCTGCTGCCGACGCTGATCACCGATACCCGCGCCGTCAG
GACCGCGGCGATAGCGGCAGGCCTCGAGGCTAAAGGAGCCGCGGTGCCGGGCTTCCTCGGCCTGCATCTCGAAGGCCCTC
ATCTCTCGGTCGCGCGTAAGGGGGCGCACGATCCCGCGCTGATCCGCCGGATGGAGGACGACGATCTCGCCGAGATACTT
GGCTGCGCAAAGGCGCTCGGCCGCCTGATGCTGACCGTGGCGCCGGAAAATGCCACAAAGGAGCAGGTTCGGGCGCTGGC
CGATGCCGGGGTCGTGGTGAGCCTTGGCCATACCGATGTGGATTACGATACCGCCCGCGCCTATGCCAAAGCGGGAGCGA
GAACCGTCACGCACCTCTTCAACGCCATGAGCGGGCCTGGTCACCGTGAGCCGGGCGTTGTCGGTGCCGCTCTGGCGACG
GGCGCTCTCCATGCCGGCATGATCGCCGACGGCTATCATGTCCACCCGGCTTCCATGGGCATAGCATTGCGCGGCAAGAA
GGGACCGGGGCAGATCTTTCTGGTCACCGACGCCATGTCGCCCCTCGGCACTGACCAGACGAGCTTCTTCCTCAACGGAC
GAAAAATCCTGCGGCAGGACGGCCGCCTGACTCTCGCCGACGGCACCCTCGCCGGCGCCGATATCGATATGTTGTCTTCT
GTTCGTTTCGTCCACCAGAGGCTCGGCCTTCCGGTCGAGGAGGCGATCCGCATGGCGTCCGCCTATCCCGCCGACGCCAT
GGGAATAGCCTCGCACAAGGGCCGGCTCCTGCCGGGTGCGGATGCCGATTTCGTGCTGCTCACGCCGGAGCTCGGCATCA
GATCGACCTGGATCGGCGGAGAAAGAGTCTTTGCCGCTTGA

Upstream 100 bases:

>100_bases
CACTGATCCTGCCGTTCTATGGCTTCGTCGAGGCCTGGTCCCGCTCTCGTGGCCTCGATCCCGACGCCCCGGAAAACCTC
AAGAAGGTGACGGAAACACG

Downstream 100 bases:

>100_bases
GGCACCTTGCCGGTGCGATGCGCTGCAAGATTGCACCGCAAGCGGAGAGAGGAGCTTTGAGCCGAGGGGGGCGGACGCCG
CCGGAAGCGTCACAGCTCGT

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MNGNKTITGARVFDGIDWHDGAALVVESGHVKSIVPAGSVAVGGETVDAHGLLLVPGFIDLQVNGGGGALLNEEPTLAGI
RQICSAHATFGTTALLPTLITDTRAVRTAAIAAGLEAKGAAVPGFLGLHLEGPHLSVARKGAHDPALIRRMEDDDLAEIL
GCAKALGRLMLTVAPENATKEQVRALADAGVVVSLGHTDVDYDTARAYAKAGARTVTHLFNAMSGPGHREPGVVGAALAT
GALHAGMIADGYHVHPASMGIALRGKKGPGQIFLVTDAMSPLGTDQTSFFLNGRKILRQDGRLTLADGTLAGADIDMLSS
VRFVHQRLGLPVEEAIRMASAYPADAMGIASHKGRLLPGADADFVLLTPELGIRSTWIGGERVFAA

Sequences:

>Translated_386_residues
MNGNKTITGARVFDGIDWHDGAALVVESGHVKSIVPAGSVAVGGETVDAHGLLLVPGFIDLQVNGGGGALLNEEPTLAGI
RQICSAHATFGTTALLPTLITDTRAVRTAAIAAGLEAKGAAVPGFLGLHLEGPHLSVARKGAHDPALIRRMEDDDLAEIL
GCAKALGRLMLTVAPENATKEQVRALADAGVVVSLGHTDVDYDTARAYAKAGARTVTHLFNAMSGPGHREPGVVGAALAT
GALHAGMIADGYHVHPASMGIALRGKKGPGQIFLVTDAMSPLGTDQTSFFLNGRKILRQDGRLTLADGTLAGADIDMLSS
VRFVHQRLGLPVEEAIRMASAYPADAMGIASHKGRLLPGADADFVLLTPELGIRSTWIGGERVFAA
>Mature_386_residues
MNGNKTITGARVFDGIDWHDGAALVVESGHVKSIVPAGSVAVGGETVDAHGLLLVPGFIDLQVNGGGGALLNEEPTLAGI
RQICSAHATFGTTALLPTLITDTRAVRTAAIAAGLEAKGAAVPGFLGLHLEGPHLSVARKGAHDPALIRRMEDDDLAEIL
GCAKALGRLMLTVAPENATKEQVRALADAGVVVSLGHTDVDYDTARAYAKAGARTVTHLFNAMSGPGHREPGVVGAALAT
GALHAGMIADGYHVHPASMGIALRGKKGPGQIFLVTDAMSPLGTDQTSFFLNGRKILRQDGRLTLADGTLAGADIDMLSS
VRFVHQRLGLPVEEAIRMASAYPADAMGIASHKGRLLPGADADFVLLTPELGIRSTWIGGERVFAA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=387, Percent_Identity=34.625322997416, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI224922791, Length=386, Percent_Identity=34.7150259067358, Blast_Score=164, Evalue=1e-40,
Organism=Escherichia coli, GI1786892, Length=380, Percent_Identity=35.5263157894737, Blast_Score=219, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17553768, Length=361, Percent_Identity=31.0249307479224, Blast_Score=151, Evalue=6e-37,
Organism=Drosophila melanogaster, GI19920392, Length=348, Percent_Identity=35.632183908046, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281361140, Length=361, Percent_Identity=34.6260387811634, Blast_Score=163, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 39829; Mature: 39829

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGNKTITGARVFDGIDWHDGAALVVESGHVKSIVPAGSVAVGGETVDAHGLLLVPGFID
CCCCCEEECHHHCCCCCCCCCCEEEEECCCEEEECCCCCEEECCCEECCCCEEEECCEEE
LQVNGGGGALLNEEPTLAGIRQICSAHATFGTTALLPTLITDTRAVRTAAIAAGLEAKGA
EEEECCCCEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AVPGFLGLHLEGPHLSVARKGAHDPALIRRMEDDDLAEILGCAKALGRLMLTVAPENATK
CCCCEEEEEECCCCCHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCCCCCH
EQVRALADAGVVVSLGHTDVDYDTARAYAKAGARTVTHLFNAMSGPGHREPGVVGAALAT
HHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
GALHAGMIADGYHVHPASMGIALRGKKGPGQIFLVTDAMSPLGTDQTSFFLNGRKILRQD
HHHHCCEECCCEEECCCCCCEEEECCCCCCEEEEEECCCCCCCCCCCEEEECCHHHHHCC
GRLTLADGTLAGADIDMLSSVRFVHQRLGLPVEEAIRMASAYPADAMGIASHKGRLLPGA
CCEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
DADFVLLTPELGIRSTWIGGERVFAA
CCCEEEECCCCCCEEEEECCCEEECC
>Mature Secondary Structure
MNGNKTITGARVFDGIDWHDGAALVVESGHVKSIVPAGSVAVGGETVDAHGLLLVPGFID
CCCCCEEECHHHCCCCCCCCCCEEEEECCCEEEECCCCCEEECCCEECCCCEEEECCEEE
LQVNGGGGALLNEEPTLAGIRQICSAHATFGTTALLPTLITDTRAVRTAAIAAGLEAKGA
EEEECCCCEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AVPGFLGLHLEGPHLSVARKGAHDPALIRRMEDDDLAEILGCAKALGRLMLTVAPENATK
CCCCEEEEEECCCCCHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCCCCCH
EQVRALADAGVVVSLGHTDVDYDTARAYAKAGARTVTHLFNAMSGPGHREPGVVGAALAT
HHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
GALHAGMIADGYHVHPASMGIALRGKKGPGQIFLVTDAMSPLGTDQTSFFLNGRKILRQD
HHHHCCEECCCEEECCCCCCEEEECCCCCCEEEEEECCCCCCCCCCCEEEECCHHHHHCC
GRLTLADGTLAGADIDMLSSVRFVHQRLGLPVEEAIRMASAYPADAMGIASHKGRLLPGA
CCEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
DADFVLLTPELGIRSTWIGGERVFAA
CCCEEEECCCCCCEEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]