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The map label for this gene is glmS [H]

Identifier: 150398598

GI number: 150398598

Start: 3616361

End: 3617386

Strand: Direct

Name: glmS [H]

Synonym: Smed_3409

Alternate gene names: 150398598

Gene position: 3616361-3617386 (Clockwise)

Preceding gene: 150398597

Following gene: 150398599

Centisome position: 95.62

GC content: 66.28

Gene sequence:

>1026_bases
ATGATGCAGACCAACATGCGGCGAGAAATCGACGAGATTCCCGAGGCCGCCGCCCGGCTGCTGGAGCACTCGGCCGCGGC
GCTGAGCGAAGCCGGAGCGGCTCTTCGTGCCAAGGATCCGGCCTTTCTGGTGACGATCGCCCGAGGATCCTCCGATCATG
CCGCGCTGTTTTTGAAATACGCGATCGAGCTCACGACAGGACGGCCCGTCGCATCGCTCGGGCCGTCGCTGGCATCGATC
TACGGCGCCGATCTGAAACTCGGCGGTGCGGCGGCGATTGCGATCTCGCAGTCCGGAAAGAGCCCGGACATCGTTGCCAT
GGCCGAAGCCGCGACGCGCGCAGGCGCCGTTTCGATCGCGCTGACGAACACGTTGCCTTCGCCGATCGCGGAAGCCTGCA
CTCACCCGCTCGACATTCTCGCAGGGCCCGAAATCGCCGTTGCGGCGACCAAGTCCTATGTCAACTCGATCGTCGCGGGT
CTTGCGGTTCTCGGCGAATGGACCGGTGACGGGGCCCTGAAGCGCGCGGTCGCCGATCTCCCGAACCAGTTCGCCAAGGC
GGTGAAGCTCGACTGGCAGGATTTTGCCCGAGACCTCGGAGAAGCCGAATCGCTCTATGTGCTGGGCCGCGGTCCGGCGC
TCGCGATCGCCAGCGAAGCGGCGCTGAAGTTCAAGGAGACGTCCGGCATGCATGCCGAGGCCTATTCTGCCGCGGAAGTG
TTGCACGGCCCGGTGGCGCTGGTCGGAGCCCGGTTCCCGGTTCTGGTGCTGGCTGCCCGCGACGCGGCAGAGACCTCGGT
GGCGGGCATCGCCGACGGCATGAGTGCCAAGGGCGCGGTCGTACACGTGACGTCCGCCCGGGCACACGACGCCAAGCGCC
TGCCCTTCGTCGAGACCGGGCACCCTCTGACCGACGCATTGGCACTGATCCTGCCGTTCTATGGCTTCGTCGAGGCCTGG
TCCCGCTCTCGTGGCCTCGATCCCGACGCCCCGGAAAACCTCAAGAAGGTGACGGAAACACGATGA

Upstream 100 bases:

>100_bases
GTCGCTCTATCGAGGCGACACCTATGATTTCGTGGCGGAGCTGACGATTCCGGAGCAGTGAGCCGGAATGGCGGCCCCCA
GTTGATTATGGAAGGACATG

Downstream 100 bases:

>100_bases
ACGGGAACAAGACGATCACCGGAGCACGGGTTTTCGACGGCATCGACTGGCACGACGGCGCCGCCCTCGTGGTCGAGTCA
GGGCACGTGAAGTCGATTGT

Product: glutamine--fructose-6-phosphate transaminase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MMQTNMRREIDEIPEAAARLLEHSAAALSEAGAALRAKDPAFLVTIARGSSDHAALFLKYAIELTTGRPVASLGPSLASI
YGADLKLGGAAAIAISQSGKSPDIVAMAEAATRAGAVSIALTNTLPSPIAEACTHPLDILAGPEIAVAATKSYVNSIVAG
LAVLGEWTGDGALKRAVADLPNQFAKAVKLDWQDFARDLGEAESLYVLGRGPALAIASEAALKFKETSGMHAEAYSAAEV
LHGPVALVGARFPVLVLAARDAAETSVAGIADGMSAKGAVVHVTSARAHDAKRLPFVETGHPLTDALALILPFYGFVEAW
SRSRGLDPDAPENLKKVTETR

Sequences:

>Translated_341_residues
MMQTNMRREIDEIPEAAARLLEHSAAALSEAGAALRAKDPAFLVTIARGSSDHAALFLKYAIELTTGRPVASLGPSLASI
YGADLKLGGAAAIAISQSGKSPDIVAMAEAATRAGAVSIALTNTLPSPIAEACTHPLDILAGPEIAVAATKSYVNSIVAG
LAVLGEWTGDGALKRAVADLPNQFAKAVKLDWQDFARDLGEAESLYVLGRGPALAIASEAALKFKETSGMHAEAYSAAEV
LHGPVALVGARFPVLVLAARDAAETSVAGIADGMSAKGAVVHVTSARAHDAKRLPFVETGHPLTDALALILPFYGFVEAW
SRSRGLDPDAPENLKKVTETR
>Mature_341_residues
MMQTNMRREIDEIPEAAARLLEHSAAALSEAGAALRAKDPAFLVTIARGSSDHAALFLKYAIELTTGRPVASLGPSLASI
YGADLKLGGAAAIAISQSGKSPDIVAMAEAATRAGAVSIALTNTLPSPIAEACTHPLDILAGPEIAVAATKSYVNSIVAG
LAVLGEWTGDGALKRAVADLPNQFAKAVKLDWQDFARDLGEAESLYVLGRGPALAIASEAALKFKETSGMHAEAYSAAEV
LHGPVALVGARFPVLVLAARDAAETSVAGIADGMSAKGAVVHVTSARAHDAKRLPFVETGHPLTDALALILPFYGFVEAW
SRSRGLDPDAPENLKKVTETR

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=362, Percent_Identity=27.9005524861878, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI205277386, Length=318, Percent_Identity=27.6729559748428, Blast_Score=99, Evalue=7e-21,
Organism=Escherichia coli, GI1790167, Length=356, Percent_Identity=27.247191011236, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17532899, Length=303, Percent_Identity=29.7029702970297, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17532897, Length=303, Percent_Identity=29.7029702970297, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17539970, Length=302, Percent_Identity=30.4635761589404, Blast_Score=101, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6322745, Length=364, Percent_Identity=28.2967032967033, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323731, Length=211, Percent_Identity=24.1706161137441, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21357745, Length=318, Percent_Identity=30.8176100628931, Blast_Score=108, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 35275; Mature: 35275

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQTNMRREIDEIPEAAARLLEHSAAALSEAGAALRAKDPAFLVTIARGSSDHAALFLKY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEEECCCCCHHHEEEEE
AIELTTGRPVASLGPSLASIYGADLKLGGAAAIAISQSGKSPDIVAMAEAATRAGAVSIA
EEEECCCCCHHHHCCHHHHHHCCCEEECCEEEEEEECCCCCCCEEEEHHHHHHCCEEEEE
LTNTLPSPIAEACTHPLDILAGPEIAVAATKSYVNSIVAGLAVLGEWTGDGALKRAVADL
EECCCCHHHHHHHCCCHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
PNQFAKAVKLDWQDFARDLGEAESLYVLGRGPALAIASEAALKFKETSGMHAEAYSAAEV
HHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCEEEEEHHHHHHHHHCCCCCHHHHHHHHH
LHGPVALVGARFPVLVLAARDAAETSVAGIADGMSAKGAVVHVTSARAHDAKRLPFVETG
HHCCHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEECCC
HPLTDALALILPFYGFVEAWSRSRGLDPDAPENLKKVTETR
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MMQTNMRREIDEIPEAAARLLEHSAAALSEAGAALRAKDPAFLVTIARGSSDHAALFLKY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEEECCCCCHHHEEEEE
AIELTTGRPVASLGPSLASIYGADLKLGGAAAIAISQSGKSPDIVAMAEAATRAGAVSIA
EEEECCCCCHHHHCCHHHHHHCCCEEECCEEEEEEECCCCCCCEEEEHHHHHHCCEEEEE
LTNTLPSPIAEACTHPLDILAGPEIAVAATKSYVNSIVAGLAVLGEWTGDGALKRAVADL
EECCCCHHHHHHHCCCHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
PNQFAKAVKLDWQDFARDLGEAESLYVLGRGPALAIASEAALKFKETSGMHAEAYSAAEV
HHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCEEEEEHHHHHHHHHCCCCCHHHHHHHHH
LHGPVALVGARFPVLVLAARDAAETSVAGIADGMSAKGAVVHVTSARAHDAKRLPFVETG
HHCCHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEECCC
HPLTDALALILPFYGFVEAWSRSRGLDPDAPENLKKVTETR
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]