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The map label for this gene is gpmA [H]

Identifier: 150398561

GI number: 150398561

Start: 3574506

End: 3575141

Strand: Direct

Name: gpmA [H]

Synonym: Smed_3372

Alternate gene names: 150398561

Gene position: 3574506-3575141 (Clockwise)

Preceding gene: 150398560

Following gene: 150398564

Centisome position: 94.52

GC content: 62.89

Gene sequence:

>636_bases
ATGAGCGGCACACTCGTCCTTGTCCGGCACGGCCAGAGCGACTGGAACCTGAAGAACCTCTTCACCGGCTGGCGCGATCC
CGACCTGACCGAGCTCGGCATCGAGGAGGCAATGGCCGGCGGCAAGGCGCTTGCCGACTACGGCATCAAATTCGACATCG
CCTTCACCTCGGATCTCATCCGTGCCCAGCGCACCTGCCAGCTGGTGCTGGACGCTGTCGATCAGTCATCGCTCGAAACG
ATCCGCGACCAGGCTTTGAACGAGCGCGACTACGGTGATCTTTCCGGCCTCAACAAAGACGATGCACGGGCGAAATGGGG
CGAGGAACAGGTCCACATCTGGCGCCGATCCTACGACGTGCCGCCGCCGGGCGGCGAGAGCCTGCGCGACACCGGCGCTC
GCGTCTGGCCTTACTATCTCACCGACATCCTGCCTCGCGTGCTTTCCGGTGAAAAGGTTCTGGTCGCCGCCCACGGCAAC
TCGCTGCGCTCGCTGGTGATGGTGCTCGACGGCTTGACCAAGGAGCAGATCCTCAAGCTCAACCTCGCGACCGGGGTGCC
AATGGTCTACAAGCTCAACGCGGATTCCACCGTCGCATCGAAGGAAGTGCTCGGAGATATGTCAGCGGCGCATTGA

Upstream 100 bases:

>100_bases
ATCTGCGGCGATCTGGGGGCGGAGCCAGAAGCCGGGCTTTTACTCCATGCTCGACGTTCTCGGGCTTGACTGACATCCTA
ATCACAAAGAGGAAATAGAA

Downstream 100 bases:

>100_bases
GAGGGCGGTTGCCCCCTCGTCCCGCTCGCGTCGAGCAGGACTCGAGCGCTCGCTCGCCGCTTGTCCCTTCCCCCGCTTGC
GGGAAGAAGGTGCCGGCAGG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MSGTLVLVRHGQSDWNLKNLFTGWRDPDLTELGIEEAMAGGKALADYGIKFDIAFTSDLIRAQRTCQLVLDAVDQSSLET
IRDQALNERDYGDLSGLNKDDARAKWGEEQVHIWRRSYDVPPPGGESLRDTGARVWPYYLTDILPRVLSGEKVLVAAHGN
SLRSLVMVLDGLTKEQILKLNLATGVPMVYKLNADSTVASKEVLGDMSAAH

Sequences:

>Translated_211_residues
MSGTLVLVRHGQSDWNLKNLFTGWRDPDLTELGIEEAMAGGKALADYGIKFDIAFTSDLIRAQRTCQLVLDAVDQSSLET
IRDQALNERDYGDLSGLNKDDARAKWGEEQVHIWRRSYDVPPPGGESLRDTGARVWPYYLTDILPRVLSGEKVLVAAHGN
SLRSLVMVLDGLTKEQILKLNLATGVPMVYKLNADSTVASKEVLGDMSAAH
>Mature_210_residues
SGTLVLVRHGQSDWNLKNLFTGWRDPDLTELGIEEAMAGGKALADYGIKFDIAFTSDLIRAQRTCQLVLDAVDQSSLETI
RDQALNERDYGDLSGLNKDDARAKWGEEQVHIWRRSYDVPPPGGESLRDTGARVWPYYLTDILPRVLSGEKVLVAAHGNS
LRSLVMVLDGLTKEQILKLNLATGVPMVYKLNADSTVASKEVLGDMSAAH

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=230, Percent_Identity=45.6521739130435, Blast_Score=203, Evalue=1e-52,
Organism=Homo sapiens, GI4505753, Length=230, Percent_Identity=48.695652173913, Blast_Score=202, Evalue=1e-52,
Organism=Homo sapiens, GI71274132, Length=230, Percent_Identity=45.6521739130435, Blast_Score=188, Evalue=3e-48,
Organism=Homo sapiens, GI4502445, Length=235, Percent_Identity=37.0212765957447, Blast_Score=153, Evalue=9e-38,
Organism=Homo sapiens, GI40353764, Length=235, Percent_Identity=37.0212765957447, Blast_Score=153, Evalue=9e-38,
Organism=Homo sapiens, GI310129614, Length=160, Percent_Identity=50.625, Blast_Score=136, Evalue=1e-32,
Organism=Escherichia coli, GI1786970, Length=227, Percent_Identity=46.2555066079295, Blast_Score=190, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6322697, Length=216, Percent_Identity=41.2037037037037, Blast_Score=158, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6324516, Length=279, Percent_Identity=25.4480286738351, Blast_Score=92, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6320183, Length=270, Percent_Identity=25.1851851851852, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324857, Length=163, Percent_Identity=28.8343558282209, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646216, Length=231, Percent_Identity=42.8571428571429, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI85725270, Length=231, Percent_Identity=44.1558441558442, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI85725272, Length=231, Percent_Identity=44.1558441558442, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24650981, Length=231, Percent_Identity=44.1558441558442, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI28571817, Length=220, Percent_Identity=34.0909090909091, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI28571815, Length=220, Percent_Identity=34.0909090909091, Blast_Score=133, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24648979, Length=220, Percent_Identity=34.0909090909091, Blast_Score=133, Evalue=7e-32,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 23270; Mature: 23138

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTLVLVRHGQSDWNLKNLFTGWRDPDLTELGIEEAMAGGKALADYGIKFDIAFTSDLI
CCCEEEEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHCCCEEEEEHHHHHH
RAQRTCQLVLDAVDQSSLETIRDQALNERDYGDLSGLNKDDARAKWGEEQVHIWRRSYDV
HHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCC
PPPGGESLRDTGARVWPYYLTDILPRVLSGEKVLVAAHGNSLRSLVMVLDGLTKEQILKL
CCCCCCCHHHCCCEEHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCHHHHEEE
NLATGVPMVYKLNADSTVASKEVLGDMSAAH
ECCCCCCEEEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGTLVLVRHGQSDWNLKNLFTGWRDPDLTELGIEEAMAGGKALADYGIKFDIAFTSDLI
CCEEEEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHCCCEEEEEHHHHHH
RAQRTCQLVLDAVDQSSLETIRDQALNERDYGDLSGLNKDDARAKWGEEQVHIWRRSYDV
HHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCC
PPPGGESLRDTGARVWPYYLTDILPRVLSGEKVLVAAHGNSLRSLVMVLDGLTKEQILKL
CCCCCCCHHHCCCEEHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCHHHHEEE
NLATGVPMVYKLNADSTVASKEVLGDMSAAH
ECCCCCCEEEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA