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The map label for this gene is dapB [H]

Identifier: 150398560

GI number: 150398560

Start: 3573660

End: 3574478

Strand: Direct

Name: dapB [H]

Synonym: Smed_3371

Alternate gene names: 150398560

Gene position: 3573660-3574478 (Clockwise)

Preceding gene: 150398559

Following gene: 150398561

Centisome position: 94.49

GC content: 66.54

Gene sequence:

>819_bases
ATGAGCGAAACGGACATGAGGCTCGTGGTGGTCGGTGCGGCCGGCCGTATGGGCCAGACGCTGATCCGGATCGTTCACGA
GACGCCCGGCGTGCGCCTTCATGCCGCCATCGAACGGAGTGGATCGCCCTTCCTCGGACGCGATGCCGGAGAGCTGGCCG
GCGTCGGCCAGATGGGGGTCGCCGTTTCCGACAAGCCGCTCGAAGCCTTCGTCGAGGCCGAGGGTGTGCTCGATTTCACG
GCGCCCTCGGCCACGGTGGAATTCGCGGACCTTGCCGCGCAGGCGCGCATCGTCCATGTCGTCGGCACGACCGGCTGCTC
GGCGGATGACGAGGCGAGGATCCGTGCCGCCGCCCGTCACGCCCGCGTCATCAAGTCAGGCAATATGAGCCTCGGCGTCA
ACCTGCTTGGCGTGCTCACGGAAAAGGCAGCGCGTGCGCTTCCGGCTCAGGGGTGGGACATAGAAATCCTCGAAATGCAC
CACAGGCACAAGGTCGATGCCCCTTCCGGCACGGCGCTGCTTCTCGGCGAGGCGGCAGCCAGAGGTCGCGGCATCAAACT
TGCGGATCACTCCGTGCGGGTACGCGACGGTCACACCGGAGCGCGGGTCGAAGGGGCAATAGGCTTTGCCACATTGCGCG
GCGGCTCCGTGATCGGCGAGCACTCGGTGGTGATCGCCGGAGAAGGCGAAATGGTCACGCTTTCCCACAGCGCGACCGAC
CGCTCGATCTTCGCTCGCGGCGCCGTATCTGCGGCGATCTGGGGGCGGAGCCAGAAGCCGGGCTTTTACTCCATGCTCGA
CGTTCTCGGGCTTGACTGA

Upstream 100 bases:

>100_bases
TACGCTCGCCTCCACAATCTCCAGGGCAGCGGAGCGGATACGGCAGCCGAGGCCCGGATCCTCTAGAGCCCGGACCTGTA
AGCATGAAGGGAAATTGACG

Downstream 100 bases:

>100_bases
CATCCTAATCACAAAGAGGAAATAGAAATGAGCGGCACACTCGTCCTTGTCCGGCACGGCCAGAGCGACTGGAACCTGAA
GAACCTCTTCACCGGCTGGC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MSETDMRLVVVGAAGRMGQTLIRIVHETPGVRLHAAIERSGSPFLGRDAGELAGVGQMGVAVSDKPLEAFVEAEGVLDFT
APSATVEFADLAAQARIVHVVGTTGCSADDEARIRAAARHARVIKSGNMSLGVNLLGVLTEKAARALPAQGWDIEILEMH
HRHKVDAPSGTALLLGEAAARGRGIKLADHSVRVRDGHTGARVEGAIGFATLRGGSVIGEHSVVIAGEGEMVTLSHSATD
RSIFARGAVSAAIWGRSQKPGFYSMLDVLGLD

Sequences:

>Translated_272_residues
MSETDMRLVVVGAAGRMGQTLIRIVHETPGVRLHAAIERSGSPFLGRDAGELAGVGQMGVAVSDKPLEAFVEAEGVLDFT
APSATVEFADLAAQARIVHVVGTTGCSADDEARIRAAARHARVIKSGNMSLGVNLLGVLTEKAARALPAQGWDIEILEMH
HRHKVDAPSGTALLLGEAAARGRGIKLADHSVRVRDGHTGARVEGAIGFATLRGGSVIGEHSVVIAGEGEMVTLSHSATD
RSIFARGAVSAAIWGRSQKPGFYSMLDVLGLD
>Mature_271_residues
SETDMRLVVVGAAGRMGQTLIRIVHETPGVRLHAAIERSGSPFLGRDAGELAGVGQMGVAVSDKPLEAFVEAEGVLDFTA
PSATVEFADLAAQARIVHVVGTTGCSADDEARIRAAARHARVIKSGNMSLGVNLLGVLTEKAARALPAQGWDIEILEMHH
RHKVDAPSGTALLLGEAAARGRGIKLADHSVRVRDGHTGARVEGAIGFATLRGGSVIGEHSVVIAGEGEMVTLSHSATDR
SIFARGAVSAAIWGRSQKPGFYSMLDVLGLD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=272, Percent_Identity=44.1176470588235, Blast_Score=202, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 28334; Mature: 28203

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETDMRLVVVGAAGRMGQTLIRIVHETPGVRLHAAIERSGSPFLGRDAGELAGVGQMGV
CCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHCCCCCCCE
AVSDKPLEAFVEAEGVLDFTAPSATVEFADLAAQARIVHVVGTTGCSADDEARIRAAARH
EECCCHHHHHHHHCCEEEECCCCCEEHHHHHHCCEEEEEEEECCCCCCCCHHHHHHHHHH
ARVIKSGNMSLGVNLLGVLTEKAARALPAQGWDIEILEMHHRHKVDAPSGTALLLGEAAA
HHHHCCCCCEECHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCCCCCEEEEECHHH
RGRGIKLADHSVRVRDGHTGARVEGAIGFATLRGGSVIGEHSVVIAGEGEMVTLSHSATD
CCCCEEEECCEEEEECCCCCCEEECEEEEEEECCCCEECCCEEEEECCCCEEEEECCCCC
RSIFARGAVSAAIWGRSQKPGFYSMLDVLGLD
CHHHHHCCCEEEECCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
SETDMRLVVVGAAGRMGQTLIRIVHETPGVRLHAAIERSGSPFLGRDAGELAGVGQMGV
CCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHCCCCCCCE
AVSDKPLEAFVEAEGVLDFTAPSATVEFADLAAQARIVHVVGTTGCSADDEARIRAAARH
EECCCHHHHHHHHCCEEEECCCCCEEHHHHHHCCEEEEEEEECCCCCCCCHHHHHHHHHH
ARVIKSGNMSLGVNLLGVLTEKAARALPAQGWDIEILEMHHRHKVDAPSGTALLLGEAAA
HHHHCCCCCEECHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCCCCCEEEEECHHH
RGRGIKLADHSVRVRDGHTGARVEGAIGFATLRGGSVIGEHSVVIAGEGEMVTLSHSATD
CCCCEEEECCEEEEECCCCCCEEECEEEEEEECCCCEECCCEEEEECCCCEEEEECCCCC
RSIFARGAVSAAIWGRSQKPGFYSMLDVLGLD
CHHHHHCCCEEEECCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]