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The map label for this gene is clpX [H]

Identifier: 150396096

GI number: 150396096

Start: 931831

End: 933108

Strand: Direct

Name: clpX [H]

Synonym: Smed_0873

Alternate gene names: 150396096

Gene position: 931831-933108 (Clockwise)

Preceding gene: 150396095

Following gene: 150396097

Centisome position: 24.64

GC content: 59.62

Gene sequence:

>1278_bases
ATGAGCAAGGTCAGCGGTAGCAACGGCGGTGACTCGAAGAATACCCTCTATTGTTCGTTTTGCGGCAAGAGCCAGCATGA
AGTCCGCAAGCTGATTGCCGGACCGACCGTGTTCATCTGCGATGAATGCGTCGAACTCTGCATGGACATCATCCGCGAAG
AGAACAAGACCTCGATGGTCAAATCTCGCGACGGCGTTCCGACGCCGCAGGAGATCATCAAGGTCCTCGACGAATACGTC
ATCGGGCAGCAGCAGGCAAAGCGCATCCTGTCGGTCGCGGTGCACAACCACTACAAGCGCCTTGCCCATGCGGCAAAGAG
CAGTGACGTAGAATTGGCGAAGTCGAACATCATGCTCGTCGGGCCCACCGGTTGCGGCAAGACTTACCTTGCGCAGACCC
TCGCCCGCATCATCGACGTTCCCTTCACGATGGCCGACGCGACGACCCTGACGGAAGCCGGTTACGTCGGTGAAGATGTC
GAAAACATCATCCTGAAGCTTCTGCAAGCCGCCGATTATAACGTCGAGCGCGCTCAGCGCGGCATCGTCTATATCGACGA
AGTCGACAAGATTTCCCGTAAATCCGACAACCCGTCGATCACGCGGGACGTCTCGGGCGAGGGCGTGCAGCAGGCGCTTC
TGAAGATCATGGAAGGGACCGTCGCTTCGGTGCCGCCTCAGGGCGGCCGCAAGCACCCGCAGCAGGAATTCCTGCAGGTG
GATACGACGAATATCCTCTTCATTTGTGGTGGCGCTTTTGCGGGCCTCGACAAGATCATTTCCGCTCGCGGCGAAAAGAC
GTCGATCGGCTTCGGCGCAACCGTGCGCGCTCCGGAAGACCGCCGGGTCGGCGAGGTGCTGCGCGAGCTCGAGCCGGAGG
ATCTGGTAAAATTCGGCCTGATACCCGAGTTCATCGGAAGGTTGCCGGTTCTGGCGACGCTCGAAGACCTCGACGAAGAT
GCGCTGATCCAGATCCTGTCGGAGCCGAAGAACGCCTTGGTCAAGCAGTATCAGCGGCTCTTCGAAATGGAAGACGTCGA
GCTGAACTTCCACGAAGACGCGCTGCGCGAGATCGCCCGGAGGGCGATCGTCCGCAAGACCGGCGCACGCGGTCTGCGTT
CGATCATGGAGAAGATCCTGCTCGACACCATGTTCGAGCTGCCGACGCTGGAAGGCGTTCGCGAGGTCGTGATTTCGGAG
GAAGTCGTAAAGGGGACGGCGCGACCGCTCTATATCTACTCGGAGCGCTCCGAGGAGAAGACCAACGTTTCGGCCTGA

Upstream 100 bases:

>100_bases
TCCCGAGAACCTTGGGCGGCGCCTGGAGCCGACGTGCAAGGCGAACTGAGTGTCCGCGATATCTTTCCGAAGGTGTCCGG
CGTGCTGGAAGGAAGTGGAA

Downstream 100 bases:

>100_bases
GCCGAGCCACTCACGATTGTTTGAAGAGCCCGCCATGTGCGGGCTTTTTCATGGGATTGCCTTTGTCATCGCGCCGGCTG
ACGCGTGGGGACCCGGGCAA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MSKVSGSNGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKTSMVKSRDGVPTPQEIIKVLDEYV
IGQQQAKRILSVAVHNHYKRLAHAAKSSDVELAKSNIMLVGPTGCGKTYLAQTLARIIDVPFTMADATTLTEAGYVGEDV
ENIILKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQV
DTTNILFICGGAFAGLDKIISARGEKTSIGFGATVRAPEDRRVGEVLRELEPEDLVKFGLIPEFIGRLPVLATLEDLDED
ALIQILSEPKNALVKQYQRLFEMEDVELNFHEDALREIARRAIVRKTGARGLRSIMEKILLDTMFELPTLEGVREVVISE
EVVKGTARPLYIYSERSEEKTNVSA

Sequences:

>Translated_425_residues
MSKVSGSNGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKTSMVKSRDGVPTPQEIIKVLDEYV
IGQQQAKRILSVAVHNHYKRLAHAAKSSDVELAKSNIMLVGPTGCGKTYLAQTLARIIDVPFTMADATTLTEAGYVGEDV
ENIILKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQV
DTTNILFICGGAFAGLDKIISARGEKTSIGFGATVRAPEDRRVGEVLRELEPEDLVKFGLIPEFIGRLPVLATLEDLDED
ALIQILSEPKNALVKQYQRLFEMEDVELNFHEDALREIARRAIVRKTGARGLRSIMEKILLDTMFELPTLEGVREVVISE
EVVKGTARPLYIYSERSEEKTNVSA
>Mature_424_residues
SKVSGSNGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKTSMVKSRDGVPTPQEIIKVLDEYVI
GQQQAKRILSVAVHNHYKRLAHAAKSSDVELAKSNIMLVGPTGCGKTYLAQTLARIIDVPFTMADATTLTEAGYVGEDVE
NIILKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVD
TTNILFICGGAFAGLDKIISARGEKTSIGFGATVRAPEDRRVGEVLRELEPEDLVKFGLIPEFIGRLPVLATLEDLDEDA
LIQILSEPKNALVKQYQRLFEMEDVELNFHEDALREIARRAIVRKTGARGLRSIMEKILLDTMFELPTLEGVREVVISEE
VVKGTARPLYIYSERSEEKTNVSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=339, Percent_Identity=53.9823008849557, Blast_Score=333, Evalue=3e-91,
Organism=Escherichia coli, GI1786642, Length=407, Percent_Identity=71.7444717444718, Blast_Score=598, Evalue=1e-172,
Organism=Escherichia coli, GI1790366, Length=104, Percent_Identity=42.3076923076923, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=328, Percent_Identity=46.6463414634146, Blast_Score=286, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI71982905, Length=313, Percent_Identity=47.6038338658147, Blast_Score=285, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI71988663, Length=391, Percent_Identity=38.3631713554987, Blast_Score=253, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=258, Percent_Identity=39.922480620155, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=432, Percent_Identity=37.7314814814815, Blast_Score=263, Evalue=5e-71,
Organism=Drosophila melanogaster, GI24648289, Length=323, Percent_Identity=50.1547987616099, Blast_Score=314, Evalue=7e-86,
Organism=Drosophila melanogaster, GI24648291, Length=323, Percent_Identity=50.1547987616099, Blast_Score=314, Evalue=8e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 47010; Mature: 46878

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVSGSNGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKTSMV
CCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHH
KSRDGVPTPQEIIKVLDEYVIGQQQAKRILSVAVHNHYKRLAHAAKSSDVELAKSNIMLV
HCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEE
GPTGCGKTYLAQTLARIIDVPFTMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQR
CCCCCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHC
GIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQV
CCEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHH
DTTNILFICGGAFAGLDKIISARGEKTSIGFGATVRAPEDRRVGEVLRELEPEDLVKFGL
CCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCEECCCCHHHHHHHHHHCCHHHHHHHCC
IPEFIGRLPVLATLEDLDEDALIQILSEPKNALVKQYQRLFEMEDVELNFHEDALREIAR
HHHHHCCCCHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
RAIVRKTGARGLRSIMEKILLDTMFELPTLEGVREVVISEEVVKGTARPLYIYSERSEEK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
TNVSA
CCCCC
>Mature Secondary Structure 
SKVSGSNGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKTSMV
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHH
KSRDGVPTPQEIIKVLDEYVIGQQQAKRILSVAVHNHYKRLAHAAKSSDVELAKSNIMLV
HCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEE
GPTGCGKTYLAQTLARIIDVPFTMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQR
CCCCCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHC
GIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQV
CCEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHH
DTTNILFICGGAFAGLDKIISARGEKTSIGFGATVRAPEDRRVGEVLRELEPEDLVKFGL
CCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCEECCCCHHHHHHHHHHCCHHHHHHHCC
IPEFIGRLPVLATLEDLDEDALIQILSEPKNALVKQYQRLFEMEDVELNFHEDALREIAR
HHHHHCCCCHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
RAIVRKTGARGLRSIMEKILLDTMFELPTLEGVREVVISEEVVKGTARPLYIYSERSEEK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
TNVSA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]