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The map label for this gene is dagK [H]

Identifier: 150395878

GI number: 150395878

Start: 706579

End: 707505

Strand: Direct

Name: dagK [H]

Synonym: Smed_0654

Alternate gene names: 150395878

Gene position: 706579-707505 (Clockwise)

Preceding gene: 150395877

Following gene: 150395881

Centisome position: 18.68

GC content: 59.12

Gene sequence:

>927_bases
TTGAAAGTCAAGGCCATCTTCAATCGAGATGGGGGGACTTTTCGAACGACGGACATGGACGCCTTCAGCAGGAAGGTCGA
GGAGGACTTTCAGGCTGCCGGTCATCGGATTGAGATCGCAGTCGTCGGATCGGACGAGATGCGAGATGCACTGGAGACTG
CCTGCCGAAGGGATGATCTCGACGCGATCGTCGCCGGCGGCGGTGACGGCACGATTTCGGCGGCGGCGGGAGTCGCCTGG
AAAACAGGCATGCCGCTCGGCATCGTCCCCGCGGGAACTATGAATCTCGTTGCGCGTTCCCTGAAGCTTCCGCTCGACAT
CTGGAAGGCTCCGGAAGTGCTTGCGGCTGGAAGAGTCATCGACGCCGACATCGGCAGCGCTGACGGTCGCGCGTTCGTGC
ATCAGTTCTCCATGGGTCTTCACGCCCGCATGGTGCGCTATCGCGAATCCTATCAATTCGCGTCGCGACTTGGAAAGATC
AGCGCCAGCACACGCGCCGCTATCGGTGTGATTTTCAATCCACCGGATTTCGAGATTGAGTTCGACGCGGACGGGCACCG
GGAGCGCCGGCATGTTTCGGCGATTTCCGTCTCGAACAACCATTTCGGCCATGACACGCTGATGTATGCGGACGATCTGA
CGAGCGGCCATCTCGGCTTCTACACGGCGCCGCCTCTAAGCCCCGCGGGCGTGACGAAGCTCTCCTTCGATATTCTTCGG
GGAAAATTCAGAAGCAGCACGCTGATCAGCGAGATGAGTGCCCTGACAGTAGATCTGCACTTCCCGAAAATGGATAGGAA
GATCAATTGCGTCATCGACGGCGAACTCGTTCCGATCAAAAGCGGTAAGGTGGCGTTGCGCGTTCATCCTGGAGAATTGA
AGCTGCTCGTCGGCCGGCAGGATGGCGACGCCGGGAATACCGTGTAG

Upstream 100 bases:

>100_bases
GGCAAAGTTACTGGTACTTTTCGTCGCCCGGCTCTGGAAACCCCCGCTGCCGCTCTTATCTGAGAAGCTGAACGCACTCG
CATGACGGAGGCAGCAGCCA

Downstream 100 bases:

>100_bases
CGGCTTCCCACGCGGCTATTCCGCAATCCAGATATAGCTGAAACTGTAGCGATCCGGGCCGGTGCCGTAGAGATAGGGCA
GGTCAAGGTGGCTTGGCGCC

Product: diacylglycerol kinase catalytic protein

Products: NA

Alternate protein names: DAG kinase; DAGK [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MKVKAIFNRDGGTFRTTDMDAFSRKVEEDFQAAGHRIEIAVVGSDEMRDALETACRRDDLDAIVAGGGDGTISAAAGVAW
KTGMPLGIVPAGTMNLVARSLKLPLDIWKAPEVLAAGRVIDADIGSADGRAFVHQFSMGLHARMVRYRESYQFASRLGKI
SASTRAAIGVIFNPPDFEIEFDADGHRERRHVSAISVSNNHFGHDTLMYADDLTSGHLGFYTAPPLSPAGVTKLSFDILR
GKFRSSTLISEMSALTVDLHFPKMDRKINCVIDGELVPIKSGKVALRVHPGELKLLVGRQDGDAGNTV

Sequences:

>Translated_308_residues
MKVKAIFNRDGGTFRTTDMDAFSRKVEEDFQAAGHRIEIAVVGSDEMRDALETACRRDDLDAIVAGGGDGTISAAAGVAW
KTGMPLGIVPAGTMNLVARSLKLPLDIWKAPEVLAAGRVIDADIGSADGRAFVHQFSMGLHARMVRYRESYQFASRLGKI
SASTRAAIGVIFNPPDFEIEFDADGHRERRHVSAISVSNNHFGHDTLMYADDLTSGHLGFYTAPPLSPAGVTKLSFDILR
GKFRSSTLISEMSALTVDLHFPKMDRKINCVIDGELVPIKSGKVALRVHPGELKLLVGRQDGDAGNTV
>Mature_308_residues
MKVKAIFNRDGGTFRTTDMDAFSRKVEEDFQAAGHRIEIAVVGSDEMRDALETACRRDDLDAIVAGGGDGTISAAAGVAW
KTGMPLGIVPAGTMNLVARSLKLPLDIWKAPEVLAAGRVIDADIGSADGRAFVHQFSMGLHARMVRYRESYQFASRLGKI
SASTRAAIGVIFNPPDFEIEFDADGHRERRHVSAISVSNNHFGHDTLMYADDLTSGHLGFYTAPPLSPAGVTKLSFDILR
GKFRSSTLISEMSALTVDLHFPKMDRKINCVIDGELVPIKSGKVALRVHPGELKLLVGRQDGDAGNTV

Specific function: Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthet

COG id: COG1597

COG function: function code IR; Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DAGKc domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017438
- InterPro:   IPR005218
- InterPro:   IPR001206 [H]

Pfam domain/function: PF00781 DAGK_cat [H]

EC number: =2.7.1.107 [H]

Molecular weight: Translated: 33294; Mature: 33294

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKAIFNRDGGTFRTTDMDAFSRKVEEDFQAAGHRIEIAVVGSDEMRDALETACRRDDL
CEEEEEEECCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCCCCC
DAIVAGGGDGTISAAAGVAWKTGMPLGIVPAGTMNLVARSLKLPLDIWKAPEVLAAGRVI
CEEEECCCCCCEEHHCCCEEECCCCEEEECCCHHHHHHHHHCCCHHHCCCCHHHHCCCEE
DADIGSADGRAFVHQFSMGLHARMVRYRESYQFASRLGKISASTRAAIGVIFNPPDFEIE
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEE
FDADGHRERRHVSAISVSNNHFGHDTLMYADDLTSGHLGFYTAPPLSPAGVTKLSFDILR
ECCCCCCCHHEEEEEEECCCCCCCCEEEEECCCCCCCCCEEECCCCCCCCCHHHHHHHHH
GKFRSSTLISEMSALTVDLHFPKMDRKINCVIDGELVPIKSGKVALRVHPGELKLLVGRQ
CCHHHHHHHHHHHEEEEEEECCCCCCEEEEEECCEEEEECCCCEEEEEECCEEEEEEECC
DGDAGNTV
CCCCCCCC
>Mature Secondary Structure
MKVKAIFNRDGGTFRTTDMDAFSRKVEEDFQAAGHRIEIAVVGSDEMRDALETACRRDDL
CEEEEEEECCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCCCCC
DAIVAGGGDGTISAAAGVAWKTGMPLGIVPAGTMNLVARSLKLPLDIWKAPEVLAAGRVI
CEEEECCCCCCEEHHCCCEEECCCCEEEECCCHHHHHHHHHCCCHHHCCCCHHHHCCCEE
DADIGSADGRAFVHQFSMGLHARMVRYRESYQFASRLGKISASTRAAIGVIFNPPDFEIE
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEE
FDADGHRERRHVSAISVSNNHFGHDTLMYADDLTSGHLGFYTAPPLSPAGVTKLSFDILR
ECCCCCCCHHEEEEEEECCCCCCCCEEEEECCCCCCCCCEEECCCCCCCCCHHHHHHHHH
GKFRSSTLISEMSALTVDLHFPKMDRKINCVIDGELVPIKSGKVALRVHPGELKLLVGRQ
CCHHHHHHHHHHHEEEEEEECCCCCCEEEEEECCEEEEECCCCEEEEEECCEEEEEEECC
DGDAGNTV
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA