Click here to switch to the map view.

The map label for this gene is cycK [H]

Identifier: 150395859

GI number: 150395859

Start: 679959

End: 681941

Strand: Direct

Name: cycK [H]

Synonym: Smed_0635

Alternate gene names: 150395859

Gene position: 679959-681941 (Clockwise)

Preceding gene: 150395858

Following gene: 150395860

Centisome position: 17.98

GC content: 64.09

Gene sequence:

>1983_bases
ATGATCATCGAACTCGGGCATTACGCGCTGGTCCTGGCGCTCGCGACCGCGATCATCCAGGGCCTCCTGCCCGTCGTCGG
GGTACGGCGCGGCGATCCCGCCTTGATGGCGCTTGCTGCAAACGCGGCGCTCGTCTGCTTTCTGCTGGTCGCATTCTCCT
TCGCCGTGCTGACATTCGCTTATGTGACGTCGGATTTCTCGGTCAAGAACGTATGGGAGAACTCGCATTCCCTTAAGCCG
CTGATCTACAAGGTCACCGGGGTCTGGGGAAATCACGAAGGCTCCATGCTCCTGTGGCTGCTGATCCTCGTCTTCTTTTC
CGCGATGGTCGCTCTCTTCGGCCGAAACCTGCCGGAGACGTTGAAGGCGAATGTGCTTGCGGTGCAGGCCTGGATCGCGA
CGGCATTCACACTCTTCGTCCTGCTGACCTCCAATCCCTTTGCGCGGCTGGTGCCGGCGCCTGGAGAGGGCAGGGACTTG
AATCCGGTGCTTCAGGATATCGGGCTGGCGATCCACCCGCCCTTGCTCTATCTCGGCTATGTCGGCTTTTCAGTCTGCTT
TTCTTTCGCGGTGGCAGCTCTCATCGAGGGGCGGATCGACGCGGCCTGGGCCCGTTGGGTGCGGCCTTGGACGCTCGCCG
CCTGGACCTTTCTCACGGCCGGCATCGCAATGGGCTCGTACTGGGCCTATTACGAGCTTGGCTGGGGCGGTTGGTGGTTC
TGGGACCCGGTCGAGAATGCCTCCTTCATGCCCTGGCTTGCCGGAACGGCCCTTCTGCACTCGGCGCTGGTCATGGAAAA
GCGCGAAGCGCTGAAGATCTGGACCGTGCTGCTGGCGATCACGACCTTCTCGCTGTCGCTGCTCGGGACCTTCCTGGTAC
GCTCCGGCGTGCTGACATCGGTCCACGCTTTCGCCACCGACCCGACCCGCGGCGTCTTCATTCTCGCCATTCTGGTGGTC
TTCATCGGCGGCGCCTTTTCGCTCTTTGCATTTCGTGCCTCCCACCTCAAAGCCGGGGGGATATTCGCGCCGATCTCGCG
CGAGGGCGCCCTTGTCCTGAACAACCTGATCCTGACGACGGCAACCGCGACGGTGCTGACCGGCACTCTCTATCCGCTGG
TGCTCGAAGCGCTGACCGGCGACAAGATCTCGGTCGGCGCGCCGTTTTTCAACATGACCTTCGGCCTGCTGATGCTGCCG
CTCGTCGCGGTCGTTCCCTTCGGTCCGCTGCTTGCCTGGAAGCGCGGCGACCTCGCCGGCGCGGCGCAGCGGCTGTTTAC
GGCTGCTGCCGTAGGCCTGCTTGCCGCCGCAGCCTGCTATTACGCGGTAAATGGCGGCCCGGTGCTGGCTCCACTCGGCC
TCGGCCTCGGCGTTTACCTCATCATCGGTGCGCTCACCGACCTTGTCCTGCGCTCCGGACTCGGCAAGGTAAAGGCCGGC
GTCGCCTGGAAGCGTTTCTCAGGCCTGCCACGTTCATCTATCGGCACGGCGCTGGCCCATATCGGTCTCGGCATTACCCT
GATAGGGATCGTCGCGGTGACAGCCTTCGAGACGGAAACGGTCGTCGAGATGAAACCGGGGGCGGTGGTCGATGTCGGGC
GCTACAGCCTGCGTTTCGACGGCATGCGCGAAGGGCGCGGGCCGAACTACACCGAGAATGCCGGCCATTTCACCATCAGC
CGCGGCGGCGTCGCCGTCAGTGAGGTCTGGTCGTCGAAGCGGCTCTATTCGGCGCGCCGCATGCCGACGACCGAAGCCGG
GATCCGGACCTTCGGCGTGAGCCAGCTCTATGTTTCCCTGGGCGATGACATGGCCGATGGAGGCATCGTCGTGCGCATCT
GGTGGAAACCGCTGATCCTGTGCATCTGGGGCGGTGCGCTCGTGATGATGGCCGGCGGAATAGTCTCGCTCACCGACAGG
CGTCTTCGCGTGGGCGCACCGGCGCGTGCCAGAAGGCCGCTTGCGGTGGGTGCTGCGGAATGA

Upstream 100 bases:

>100_bases
ACACCGTGCTCGCCAAGCATGATGAGACCTACATGCCGAAGGATGTCGCAGATCGCCTCAAGGCCCAGGGGGTCACGCTT
GGCGGGGAGGAAAACATCCG

Downstream 100 bases:

>100_bases
TCCGGCTGCTCCTCGCACTTCTCCTCTTGCTGGCATCCGCGATGCCGGGTCTCGCCGTGAATCCTGACGAGGTGCTCGCA
GATCCGGCGCTTGAAACCCG

Product: cytochrome c-type biogenesis protein CcmF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
MIIELGHYALVLALATAIIQGLLPVVGVRRGDPALMALAANAALVCFLLVAFSFAVLTFAYVTSDFSVKNVWENSHSLKP
LIYKVTGVWGNHEGSMLLWLLILVFFSAMVALFGRNLPETLKANVLAVQAWIATAFTLFVLLTSNPFARLVPAPGEGRDL
NPVLQDIGLAIHPPLLYLGYVGFSVCFSFAVAALIEGRIDAAWARWVRPWTLAAWTFLTAGIAMGSYWAYYELGWGGWWF
WDPVENASFMPWLAGTALLHSALVMEKREALKIWTVLLAITTFSLSLLGTFLVRSGVLTSVHAFATDPTRGVFILAILVV
FIGGAFSLFAFRASHLKAGGIFAPISREGALVLNNLILTTATATVLTGTLYPLVLEALTGDKISVGAPFFNMTFGLLMLP
LVAVVPFGPLLAWKRGDLAGAAQRLFTAAAVGLLAAAACYYAVNGGPVLAPLGLGLGVYLIIGALTDLVLRSGLGKVKAG
VAWKRFSGLPRSSIGTALAHIGLGITLIGIVAVTAFETETVVEMKPGAVVDVGRYSLRFDGMREGRGPNYTENAGHFTIS
RGGVAVSEVWSSKRLYSARRMPTTEAGIRTFGVSQLYVSLGDDMADGGIVVRIWWKPLILCIWGGALVMMAGGIVSLTDR
RLRVGAPARARRPLAVGAAE

Sequences:

>Translated_660_residues
MIIELGHYALVLALATAIIQGLLPVVGVRRGDPALMALAANAALVCFLLVAFSFAVLTFAYVTSDFSVKNVWENSHSLKP
LIYKVTGVWGNHEGSMLLWLLILVFFSAMVALFGRNLPETLKANVLAVQAWIATAFTLFVLLTSNPFARLVPAPGEGRDL
NPVLQDIGLAIHPPLLYLGYVGFSVCFSFAVAALIEGRIDAAWARWVRPWTLAAWTFLTAGIAMGSYWAYYELGWGGWWF
WDPVENASFMPWLAGTALLHSALVMEKREALKIWTVLLAITTFSLSLLGTFLVRSGVLTSVHAFATDPTRGVFILAILVV
FIGGAFSLFAFRASHLKAGGIFAPISREGALVLNNLILTTATATVLTGTLYPLVLEALTGDKISVGAPFFNMTFGLLMLP
LVAVVPFGPLLAWKRGDLAGAAQRLFTAAAVGLLAAAACYYAVNGGPVLAPLGLGLGVYLIIGALTDLVLRSGLGKVKAG
VAWKRFSGLPRSSIGTALAHIGLGITLIGIVAVTAFETETVVEMKPGAVVDVGRYSLRFDGMREGRGPNYTENAGHFTIS
RGGVAVSEVWSSKRLYSARRMPTTEAGIRTFGVSQLYVSLGDDMADGGIVVRIWWKPLILCIWGGALVMMAGGIVSLTDR
RLRVGAPARARRPLAVGAAE
>Mature_660_residues
MIIELGHYALVLALATAIIQGLLPVVGVRRGDPALMALAANAALVCFLLVAFSFAVLTFAYVTSDFSVKNVWENSHSLKP
LIYKVTGVWGNHEGSMLLWLLILVFFSAMVALFGRNLPETLKANVLAVQAWIATAFTLFVLLTSNPFARLVPAPGEGRDL
NPVLQDIGLAIHPPLLYLGYVGFSVCFSFAVAALIEGRIDAAWARWVRPWTLAAWTFLTAGIAMGSYWAYYELGWGGWWF
WDPVENASFMPWLAGTALLHSALVMEKREALKIWTVLLAITTFSLSLLGTFLVRSGVLTSVHAFATDPTRGVFILAILVV
FIGGAFSLFAFRASHLKAGGIFAPISREGALVLNNLILTTATATVLTGTLYPLVLEALTGDKISVGAPFFNMTFGLLMLP
LVAVVPFGPLLAWKRGDLAGAAQRLFTAAAVGLLAAAACYYAVNGGPVLAPLGLGLGVYLIIGALTDLVLRSGLGKVKAG
VAWKRFSGLPRSSIGTALAHIGLGITLIGIVAVTAFETETVVEMKPGAVVDVGRYSLRFDGMREGRGPNYTENAGHFTIS
RGGVAVSEVWSSKRLYSARRMPTTEAGIRTFGVSQLYVSLGDDMADGGIVVRIWWKPLILCIWGGALVMMAGGIVSLTDR
RLRVGAPARARRPLAVGAAE

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=659, Percent_Identity=44.6130500758725, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI1790511, Length=384, Percent_Identity=47.1354166666667, Blast_Score=278, Evalue=8e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 70530; Mature: 70530

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIELGHYALVLALATAIIQGLLPVVGVRRGDPALMALAANAALVCFLLVAFSFAVLTFA
CEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVTSDFSVKNVWENSHSLKPLIYKVTGVWGNHEGSMLLWLLILVFFSAMVALFGRNLPET
HHHCCCCHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
LKANVLAVQAWIATAFTLFVLLTSNPFARLVPAPGEGRDLNPVLQDIGLAIHPPLLYLGY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHCCCCCCCHHHHHHH
VGFSVCFSFAVAALIEGRIDAAWARWVRPWTLAAWTFLTAGIAMGSYWAYYELGWGGWWF
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCEEE
WDPVENASFMPWLAGTALLHSALVMEKREALKIWTVLLAITTFSLSLLGTFLVRSGVLTS
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
VHAFATDPTRGVFILAILVVFIGGAFSLFAFRASHLKAGGIFAPISREGALVLNNLILTT
HHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHH
ATATVLTGTLYPLVLEALTGDKISVGAPFFNMTFGLLMLPLVAVVPFGPLLAWKRGDLAG
HHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHH
AAQRLFTAAAVGLLAAAACYYAVNGGPVLAPLGLGLGVYLIIGALTDLVLRSGLGKVKAG
HHHHHHHHHHHHHHHHHHHHHEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHC
VAWKRFSGLPRSSIGTALAHIGLGITLIGIVAVTAFETETVVEMKPGAVVDVGRYSLRFD
CHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCEEEEEC
GMREGRGPNYTENAGHFTISRGGVAVSEVWSSKRLYSARRMPTTEAGIRTFGVSQLYVSL
CCCCCCCCCCCCCCCEEEEECCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GDDMADGGIVVRIWWKPLILCIWGGALVMMAGGIVSLTDRRLRVGAPARARRPLAVGAAE
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEECCCCEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIIELGHYALVLALATAIIQGLLPVVGVRRGDPALMALAANAALVCFLLVAFSFAVLTFA
CEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVTSDFSVKNVWENSHSLKPLIYKVTGVWGNHEGSMLLWLLILVFFSAMVALFGRNLPET
HHHCCCCHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
LKANVLAVQAWIATAFTLFVLLTSNPFARLVPAPGEGRDLNPVLQDIGLAIHPPLLYLGY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHCCCCCCCHHHHHHH
VGFSVCFSFAVAALIEGRIDAAWARWVRPWTLAAWTFLTAGIAMGSYWAYYELGWGGWWF
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCEEE
WDPVENASFMPWLAGTALLHSALVMEKREALKIWTVLLAITTFSLSLLGTFLVRSGVLTS
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
VHAFATDPTRGVFILAILVVFIGGAFSLFAFRASHLKAGGIFAPISREGALVLNNLILTT
HHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHH
ATATVLTGTLYPLVLEALTGDKISVGAPFFNMTFGLLMLPLVAVVPFGPLLAWKRGDLAG
HHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHH
AAQRLFTAAAVGLLAAAACYYAVNGGPVLAPLGLGLGVYLIIGALTDLVLRSGLGKVKAG
HHHHHHHHHHHHHHHHHHHHHEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHC
VAWKRFSGLPRSSIGTALAHIGLGITLIGIVAVTAFETETVVEMKPGAVVDVGRYSLRFD
CHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCEEEEEC
GMREGRGPNYTENAGHFTISRGGVAVSEVWSSKRLYSARRMPTTEAGIRTFGVSQLYVSL
CCCCCCCCCCCCCCCEEEEECCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GDDMADGGIVVRIWWKPLILCIWGGALVMMAGGIVSLTDRRLRVGAPARARRPLAVGAAE
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEECCCCEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7715602; 11481430 [H]