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The map label for this gene is ccmE [H]

Identifier: 150395858

GI number: 150395858

Start: 679510

End: 679962

Strand: Direct

Name: ccmE [H]

Synonym: Smed_0634

Alternate gene names: 150395858

Gene position: 679510-679962 (Clockwise)

Preceding gene: 150395857

Following gene: 150395859

Centisome position: 17.97

GC content: 62.47

Gene sequence:

>453_bases
ATGACACGCAAGCAGAAACGATTGGCAATCATCGGAGGTGGCGTCGGATTTCTGACGGCGGCGGTCCTGCTCGTCATGTT
CGCTTTTAGCCAGGCGGTCGCCTATTTCTACGTCCCGGGAGATCTTACGAAAGCCGACGTCGCGCCGGGGACGCGTATCC
GCCTCGGCGGGCTTGTCGAGGCAGGCTCCGTCAAACGCGGCGAGGGCAGGACCATTACCTTCAAGGTGACGGATACGCTT
GCGACCGTTCCGGTGACCTATACGGGTATCTTGCCCGACCTCTTCCGCGAGGGGCAGGGCGTCGTGGCCGAGGGTGCCTT
CGTCGGCGGCAGCCCGGTTTTCGTTGCGGACACCGTGCTCGCCAAGCATGATGAGACCTACATGCCGAAGGATGTCGCAG
ATCGCCTCAAGGCCCAGGGGGTCACGCTTGGCGGGGAGGAAAACATCCGATGA

Upstream 100 bases:

>100_bases
TGCACGAAGGACTGATCGCATTCCCGGCAACGGGCGTACAGGGGAAGCAACTGCTGGCTTTGGCTCAGGAACTGGGGCTC
GACGCCGGCGGAGACACTGA

Downstream 100 bases:

>100_bases
TCATCGAACTCGGGCATTACGCGCTGGTCCTGGCGCTCGCGACCGCGATCATCCAGGGCCTCCTGCCCGTCGTCGGGGTA
CGGCGCGGCGATCCCGCCTT

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MTRKQKRLAIIGGGVGFLTAAVLLVMFAFSQAVAYFYVPGDLTKADVAPGTRIRLGGLVEAGSVKRGEGRTITFKVTDTL
ATVPVTYTGILPDLFREGQGVVAEGAFVGGSPVFVADTVLAKHDETYMPKDVADRLKAQGVTLGGEENIR

Sequences:

>Translated_150_residues
MTRKQKRLAIIGGGVGFLTAAVLLVMFAFSQAVAYFYVPGDLTKADVAPGTRIRLGGLVEAGSVKRGEGRTITFKVTDTL
ATVPVTYTGILPDLFREGQGVVAEGAFVGGSPVFVADTVLAKHDETYMPKDVADRLKAQGVTLGGEENIR
>Mature_149_residues
TRKQKRLAIIGGGVGFLTAAVLLVMFAFSQAVAYFYVPGDLTKADVAPGTRIRLGGLVEAGSVKRGEGRTITFKVTDTLA
TVPVTYTGILPDLFREGQGVVAEGAFVGGSPVFVADTVLAKHDETYMPKDVADRLKAQGVTLGGEENIR

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH [H]

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family [H]

Homologues:

Organism=Escherichia coli, GI1788525, Length=144, Percent_Identity=39.5833333333333, Blast_Score=100, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004329
- InterPro:   IPR012340 [H]

Pfam domain/function: PF03100 CcmE [H]

EC number: NA

Molecular weight: Translated: 15833; Mature: 15701

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKQKRLAIIGGGVGFLTAAVLLVMFAFSQAVAYFYVPGDLTKADVAPGTRIRLGGLVE
CCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEEEECCEEE
AGSVKRGEGRTITFKVTDTLATVPVTYTGILPDLFREGQGVVAEGAFVGGSPVFVADTVL
CCCEECCCCCEEEEEECCCEEECCEEEECCCHHHHHCCCCEEECCEEECCCCEEEEHHHH
AKHDETYMPKDVADRLKAQGVTLGGEENIR
HCCCCCCCCHHHHHHHHHCCCEECCCCCCC
>Mature Secondary Structure 
TRKQKRLAIIGGGVGFLTAAVLLVMFAFSQAVAYFYVPGDLTKADVAPGTRIRLGGLVE
CCCCCEEEEEECCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEEEECCEEE
AGSVKRGEGRTITFKVTDTLATVPVTYTGILPDLFREGQGVVAEGAFVGGSPVFVADTVL
CCCEECCCCCEEEEEECCCEEECCEEEECCCHHHHHCCCCEEECCEEECCCCEEEEHHHH
AKHDETYMPKDVADRLKAQGVTLGGEENIR
HCCCCCCCCHHHHHHHHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7715602; 11481430 [H]