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The map label for this gene is tlyC [H]

Identifier: 150395271

GI number: 150395271

Start: 44129

End: 45304

Strand: Direct

Name: tlyC [H]

Synonym: Smed_0043

Alternate gene names: 150395271

Gene position: 44129-45304 (Clockwise)

Preceding gene: 150395270

Following gene: 150395272

Centisome position: 1.17

GC content: 64.29

Gene sequence:

>1176_bases
ATGAGCGACTTCAAGACAGAGCCGGCCGCTGTCGCGACCGAGGAGGCTGAAGCCTCCGGCGACGCCGAGGCCGGTAGTAG
TACCGCCGCCCGATCCGAGGGCAGCAAATCCACATCATCCTTCTGGAGCCGTGCCGCGCGCCTGTTGCGCGGTGTGAGTC
CATCAAGCCTGCGCGAGGATCTTGCCGACGCGCTGATGACCGACACCGGAGGCAATGCGGCCTTCTCGCCCGAAGAGCGG
GCGATGCTCAACAACATCCTCCGCTTTCGCGAGGTTCGTGTTGAAGACGTGATGGTTCCGCGAGCCGACATAGAGGCGGT
GGACCAGAACATCACCATCGGCGAACTCATGGCCCTCTTCGAGGAGTCTGGTCGCTCGCGTATGCCGGTCTACAGCGAAG
GGCTCGACGATCCCCGCGGCATGGTCCACATCCGCGATCTCCTTGCCTATGTGGCCAAGCAGGCGCGCAACCGGCGCCGC
AACGGCAAAGCTCCAACGGCGCCGACGACCGCAACGACCACGAATGGCGACAAGCCCGAAAAGGCCCCCCGACAGCAGAA
GCCGGGTTTCGATCTCTCTCGCGTTGACCTCGACAAGACGGTCGAGGAGGCGGGAATCATCCGTCAGCTGCTGTTCGTGC
CGCCGTCGATGCTTGCCTCGGATCTCATGCAGCGCATGCGCGCTGCGCGCATTCAGATGGCTCTCGTCATCGACGAATAC
GGCGGGACGGACGGTCTTGTATCGCTCGAGGACATCGTCGAGATGGTGGTCGGCGATATCGAGGATGAGCACGACGACGA
GGAGGTGATGTTCGCGCGCAGCTCCGACGACGTCTTCATCGCCGACGCTCGTGTGGAGCTGGAGGAAATCGCCGAGGCGG
TCGGGCCGGACTTCGATGTACGCGAGCAACTCGAGGACGTCGATACGCTTGGCGGTCTCGTTTTCGCATCGCTCGGCCGG
ATTCCCGTTCGAGGCGAGGTGGTGCAGGCGATTCCCGGTTTCGAGTTCCAGATACTCGATGCGGATCCACGTCGCGTCAA
ACGCGTCAGGATCATGCGCAAGCGCCCGTCTTCGCGCCGCCGCCCGCCGAAGGTCGAGAAGGAGCCGCTGCCAGAGGCGT
TTGCCACGACCGGCGCCACGGGCGCCGGTGTCCGGCCTCCGGCTTCGTTGGAATAG

Upstream 100 bases:

>100_bases
CGAAGCGGAGAGAATGGAGCGGTTGGAGACTCGCATTTTGGCGCGTCTTGGCCTATCTGATCCCTACGGGGACCTTCCCC
CGGTTTGACAGTTTGGAACA

Downstream 100 bases:

>100_bases
TGCCCGCCGGCGTCAAAGATGCGTCATCCTTCGGACGTGCTGATCCCGAGCGACGCGGCCCTTTTCCCGGTCGGGAAGTG
CACGGGCGATGAGGTGCATC

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSDFKTEPAAVATEEAEASGDAEAGSSTAARSEGSKSTSSFWSRAARLLRGVSPSSLREDLADALMTDTGGNAAFSPEER
AMLNNILRFREVRVEDVMVPRADIEAVDQNITIGELMALFEESGRSRMPVYSEGLDDPRGMVHIRDLLAYVAKQARNRRR
NGKAPTAPTTATTTNGDKPEKAPRQQKPGFDLSRVDLDKTVEEAGIIRQLLFVPPSMLASDLMQRMRAARIQMALVIDEY
GGTDGLVSLEDIVEMVVGDIEDEHDDEEVMFARSSDDVFIADARVELEEIAEAVGPDFDVREQLEDVDTLGGLVFASLGR
IPVRGEVVQAIPGFEFQILDADPRRVKRVRIMRKRPSSRRRPPKVEKEPLPEAFATTGATGAGVRPPASLE

Sequences:

>Translated_391_residues
MSDFKTEPAAVATEEAEASGDAEAGSSTAARSEGSKSTSSFWSRAARLLRGVSPSSLREDLADALMTDTGGNAAFSPEER
AMLNNILRFREVRVEDVMVPRADIEAVDQNITIGELMALFEESGRSRMPVYSEGLDDPRGMVHIRDLLAYVAKQARNRRR
NGKAPTAPTTATTTNGDKPEKAPRQQKPGFDLSRVDLDKTVEEAGIIRQLLFVPPSMLASDLMQRMRAARIQMALVIDEY
GGTDGLVSLEDIVEMVVGDIEDEHDDEEVMFARSSDDVFIADARVELEEIAEAVGPDFDVREQLEDVDTLGGLVFASLGR
IPVRGEVVQAIPGFEFQILDADPRRVKRVRIMRKRPSSRRRPPKVEKEPLPEAFATTGATGAGVRPPASLE
>Mature_390_residues
SDFKTEPAAVATEEAEASGDAEAGSSTAARSEGSKSTSSFWSRAARLLRGVSPSSLREDLADALMTDTGGNAAFSPEERA
MLNNILRFREVRVEDVMVPRADIEAVDQNITIGELMALFEESGRSRMPVYSEGLDDPRGMVHIRDLLAYVAKQARNRRRN
GKAPTAPTTATTTNGDKPEKAPRQQKPGFDLSRVDLDKTVEEAGIIRQLLFVPPSMLASDLMQRMRAARIQMALVIDEYG
GTDGLVSLEDIVEMVVGDIEDEHDDEEVMFARSSDDVFIADARVELEEIAEAVGPDFDVREQLEDVDTLGGLVFASLGRI
PVRGEVVQAIPGFEFQILDADPRRVKRVRIMRKRPSSRRRPPKVEKEPLPEAFATTGATGAGVRPPASLE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=285, Percent_Identity=24.5614035087719, Blast_Score=96, Evalue=7e-20,
Organism=Escherichia coli, GI1786879, Length=334, Percent_Identity=29.0419161676647, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI87082033, Length=301, Percent_Identity=25.5813953488372, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI145693175, Length=278, Percent_Identity=24.4604316546763, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 42813; Mature: 42682

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFKTEPAAVATEEAEASGDAEAGSSTAARSEGSKSTSSFWSRAARLLRGVSPSSLRED
CCCCCCCCCHHCCHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
LADALMTDTGGNAAFSPEERAMLNNILRFREVRVEDVMVPRADIEAVDQNITIGELMALF
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHH
EESGRSRMPVYSEGLDDPRGMVHIRDLLAYVAKQARNRRRNGKAPTAPTTATTTNGDKPE
HHCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
KAPRQQKPGFDLSRVDLDKTVEEAGIIRQLLFVPPSMLASDLMQRMRAARIQMALVIDEY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEECC
GGTDGLVSLEDIVEMVVGDIEDEHDDEEVMFARSSDDVFIADARVELEEIAEAVGPDFDV
CCCCCCEEHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEECHHHHHHHHHHHCCCCHH
REQLEDVDTLGGLVFASLGRIPVRGEVVQAIPGFEFQILDADPRRVKRVRIMRKRPSSRR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCC
RPPKVEKEPLPEAFATTGATGAGVRPPASLE
CCCCCCCCCCCHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDFKTEPAAVATEEAEASGDAEAGSSTAARSEGSKSTSSFWSRAARLLRGVSPSSLRED
CCCCCCCCHHCCHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
LADALMTDTGGNAAFSPEERAMLNNILRFREVRVEDVMVPRADIEAVDQNITIGELMALF
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHH
EESGRSRMPVYSEGLDDPRGMVHIRDLLAYVAKQARNRRRNGKAPTAPTTATTTNGDKPE
HHCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
KAPRQQKPGFDLSRVDLDKTVEEAGIIRQLLFVPPSMLASDLMQRMRAARIQMALVIDEY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEECC
GGTDGLVSLEDIVEMVVGDIEDEHDDEEVMFARSSDDVFIADARVELEEIAEAVGPDFDV
CCCCCCEEHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEECHHHHHHHHHHHCCCCHH
REQLEDVDTLGGLVFASLGRIPVRGEVVQAIPGFEFQILDADPRRVKRVRIMRKRPSSRR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCC
RPPKVEKEPLPEAFATTGATGAGVRPPASLE
CCCCCCCCCCCHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA