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The map label for this gene is lnt [H]

Identifier: 150395272

GI number: 150395272

Start: 45522

End: 47153

Strand: Direct

Name: lnt [H]

Synonym: Smed_0044

Alternate gene names: 150395272

Gene position: 45522-47153 (Clockwise)

Preceding gene: 150395271

Following gene: 150395273

Centisome position: 1.2

GC content: 60.91

Gene sequence:

>1632_bases
ATGCCTTGCCCACGACCGGCGCCGACTGGAGGTTCAATGGAAAGACTGGCAGGCAGAATCATACTTCTCTCCGGGGTGTC
GCGGGCATTCGTCGGTTTTCTCGCCGGCCTCCTGGCGGTGCTTGCCCAGCCGCCATTTGGCATTTTCGCGGCGGCTTTCG
TCTCTTTTCCAGTCCTCGTCTGGCTGATCGACGGGGTGGCGCCCGATCCCTCCGACGGCGCATTCCGGCGGCTGAGGCAG
CCCGCCGCAATCGGCTGGTCCTTCGGCTTCGGCTATTTTCTGGGCGGTCTCTGGTGGCTGGGCAATGCGCTCCTGGTCGA
AGCGGACGCGTTCGCCTGGGCGATACCCCTTGCCGTCGTCGGCCTTCCAGCCGTTCTCGGGGTTTTTTACGCGCTGGCGG
TCGTCATTGCCCGCTGTCTTTGGTCCGACGGCTGGGGCCGGATCGCTGCCCTTGCGCTCGGCTTCGGCATCGCCGAATGG
CTCCGCGGTTTTGTTTTTACCGGCTTTCCGTGGAATGCCATCGGTTATGCGGCCATGCCGATGCCGTTGATGATGCAGTC
GGCAAGCGTCGTCAATCTCTCAACGATCAACATGCTGGCCGTCTTTGTGTTCGCCGCTCCTGCTTTGATCTGGACGGGCA
AGGGCGCGCGCACCGGCCTTGCCATCGCGGTAGCGCTCTTTACGGCGCATATCGCATTCGGCTTCTACCGGCTCGCTCAG
CCGGCGCCGCCGTCGGCTGCACCGCAAATGGCGGTACGCGTCGTACAGCCGGTCATCGACCAGGCCAAAAAGCTCGACGA
CCGCGAGCGCGCCTCGATCTTCGAGGACCACCTCTCATTGACGGCCGCCCCGGTTCAAGGTGGCGGCAAGCGTCCGGACA
TCGTCGTTTGGCCGGAAACGTCGATCCCTTTCATCCTCACCGACAATCCCGACGCGCTGGCGCGGATCGCGGAGGTTCTC
AAGGATGGGCAGATACTCGTCGCCGGCGCCGTCAGGGCCGAGGATGCAGGCGCCGGGCTGCCGTCGCGCTACTATAACTC
TGTCTATGTTATTGACGACCGGGGCCAGATCATTGGCGCGGCGGACAAGGTGCATCTGGTGCCGTTCGGTGAATATCTCC
CCTACGAGGACCTGCTGACGTCCTGGGGCTTGAGTTCCATCGCGGCTTCGATGCCGGGCGGCTTCTCGGCAGCCAGGATG
CGCCCTGTGCTCACTTTGCCGGGCGGCAGAAGACTTTACCCGATGATCTGTTACGAGGCGATCTTTGCCGATGAGGTGGA
CGCCAATGCGCGCCTCGCCGACGTGCTCCTCAATGTCACCAACGATGCCTGGTTCGGTGACACGCCAGGTCCGCGCCAGC
ATTTCCATCAGGCGCAGCTCCGCGCGGTTGAAACCGGAATTCCCATGATCCGCGCTGCGAATACTGGTATTTCAGCAGTT
GTTGATGCACGTGGTGTTTTAGTGTTAGTATTAGGCTACAATTACAGGGGTGTTTTAGACACAATTCTGCCGGGAAAACT
GCCTACGCTAACGGACGTCCCGACGCGCAGCCGGATTTTTTGGTTGTCGATGGCTATTCTATCTATAGTTGCATCATTCT
CGCGTTTTGGTTTCAATATTAGGAAGAATTGA

Upstream 100 bases:

>100_bases
ACGGGACAAGCAGCCACTTTTTTGGAAGACTGCCGCCGATTGATTCGGTCGGCTGCGTGTGTCCTTGAATCGCAGCCGTT
TCAAGGACAGGGTCCGCACG

Downstream 100 bases:

>100_bases
CGTAAAACCCCCAAAATTGCATAGTGAATGCTTCATCAACCCTTATCTGTCGCCGAGCGCGCCGGGGTTGCTGTGGCGCA
AAAGAAGACAATTCTAGGTT

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase; ACT206; Acid-inducible protein [H]

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MPCPRPAPTGGSMERLAGRIILLSGVSRAFVGFLAGLLAVLAQPPFGIFAAAFVSFPVLVWLIDGVAPDPSDGAFRRLRQ
PAAIGWSFGFGYFLGGLWWLGNALLVEADAFAWAIPLAVVGLPAVLGVFYALAVVIARCLWSDGWGRIAALALGFGIAEW
LRGFVFTGFPWNAIGYAAMPMPLMMQSASVVNLSTINMLAVFVFAAPALIWTGKGARTGLAIAVALFTAHIAFGFYRLAQ
PAPPSAAPQMAVRVVQPVIDQAKKLDDRERASIFEDHLSLTAAPVQGGGKRPDIVVWPETSIPFILTDNPDALARIAEVL
KDGQILVAGAVRAEDAGAGLPSRYYNSVYVIDDRGQIIGAADKVHLVPFGEYLPYEDLLTSWGLSSIAASMPGGFSAARM
RPVLTLPGGRRLYPMICYEAIFADEVDANARLADVLLNVTNDAWFGDTPGPRQHFHQAQLRAVETGIPMIRAANTGISAV
VDARGVLVLVLGYNYRGVLDTILPGKLPTLTDVPTRSRIFWLSMAILSIVASFSRFGFNIRKN

Sequences:

>Translated_543_residues
MPCPRPAPTGGSMERLAGRIILLSGVSRAFVGFLAGLLAVLAQPPFGIFAAAFVSFPVLVWLIDGVAPDPSDGAFRRLRQ
PAAIGWSFGFGYFLGGLWWLGNALLVEADAFAWAIPLAVVGLPAVLGVFYALAVVIARCLWSDGWGRIAALALGFGIAEW
LRGFVFTGFPWNAIGYAAMPMPLMMQSASVVNLSTINMLAVFVFAAPALIWTGKGARTGLAIAVALFTAHIAFGFYRLAQ
PAPPSAAPQMAVRVVQPVIDQAKKLDDRERASIFEDHLSLTAAPVQGGGKRPDIVVWPETSIPFILTDNPDALARIAEVL
KDGQILVAGAVRAEDAGAGLPSRYYNSVYVIDDRGQIIGAADKVHLVPFGEYLPYEDLLTSWGLSSIAASMPGGFSAARM
RPVLTLPGGRRLYPMICYEAIFADEVDANARLADVLLNVTNDAWFGDTPGPRQHFHQAQLRAVETGIPMIRAANTGISAV
VDARGVLVLVLGYNYRGVLDTILPGKLPTLTDVPTRSRIFWLSMAILSIVASFSRFGFNIRKN
>Mature_542_residues
PCPRPAPTGGSMERLAGRIILLSGVSRAFVGFLAGLLAVLAQPPFGIFAAAFVSFPVLVWLIDGVAPDPSDGAFRRLRQP
AAIGWSFGFGYFLGGLWWLGNALLVEADAFAWAIPLAVVGLPAVLGVFYALAVVIARCLWSDGWGRIAALALGFGIAEWL
RGFVFTGFPWNAIGYAAMPMPLMMQSASVVNLSTINMLAVFVFAAPALIWTGKGARTGLAIAVALFTAHIAFGFYRLAQP
APPSAAPQMAVRVVQPVIDQAKKLDDRERASIFEDHLSLTAAPVQGGGKRPDIVVWPETSIPFILTDNPDALARIAEVLK
DGQILVAGAVRAEDAGAGLPSRYYNSVYVIDDRGQIIGAADKVHLVPFGEYLPYEDLLTSWGLSSIAASMPGGFSAARMR
PVLTLPGGRRLYPMICYEAIFADEVDANARLADVLLNVTNDAWFGDTPGPRQHFHQAQLRAVETGIPMIRAANTGISAVV
DARGVLVLVLGYNYRGVLDTILPGKLPTLTDVPTRSRIFWLSMAILSIVASFSRFGFNIRKN

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=487, Percent_Identity=30.5954825462012, Blast_Score=163, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 58179; Mature: 58048

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPCPRPAPTGGSMERLAGRIILLSGVSRAFVGFLAGLLAVLAQPPFGIFAAAFVSFPVLV
CCCCCCCCCCCCHHHHHCEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
WLIDGVAPDPSDGAFRRLRQPAAIGWSFGFGYFLGGLWWLGNALLVEADAFAWAIPLAVV
HHHHCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHH
GLPAVLGVFYALAVVIARCLWSDGWGRIAALALGFGIAEWLRGFVFTGFPWNAIGYAAMP
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCHHCCHHHCC
MPLMMQSASVVNLSTINMLAVFVFAAPALIWTGKGARTGLAIAVALFTAHIAFGFYRLAQ
HHHHHCCCCEEEHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHCC
PAPPSAAPQMAVRVVQPVIDQAKKLDDRERASIFEDHLSLTAAPVQGGGKRPDIVVWPET
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEECCCCCCCCCEEEECCC
SIPFILTDNPDALARIAEVLKDGQILVAGAVRAEDAGAGLPSRYYNSVYVIDDRGQIIGA
CCCEEEECCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHCCEEEEECCCCCEEEC
ADKVHLVPFGEYLPYEDLLTSWGLSSIAASMPGGFSAARMRPVLTLPGGRRLYPMICYEA
CCEEEEEECCCCCCHHHHHHHCCHHHHHHHCCCCCCHHHCCEEEECCCCCCCHHHHHHHH
IFADEVDANARLADVLLNVTNDAWFGDTPGPRQHFHQAQLRAVETGIPMIRAANTGISAV
HHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHH
VDARGVLVLVLGYNYRGVLDTILPGKLPTLTDVPTRSRIFWLSMAILSIVASFSRFGFNI
CCCCCEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEE
RKN
CCC
>Mature Secondary Structure 
PCPRPAPTGGSMERLAGRIILLSGVSRAFVGFLAGLLAVLAQPPFGIFAAAFVSFPVLV
CCCCCCCCCCCHHHHHCEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
WLIDGVAPDPSDGAFRRLRQPAAIGWSFGFGYFLGGLWWLGNALLVEADAFAWAIPLAVV
HHHHCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHH
GLPAVLGVFYALAVVIARCLWSDGWGRIAALALGFGIAEWLRGFVFTGFPWNAIGYAAMP
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCHHCCHHHCC
MPLMMQSASVVNLSTINMLAVFVFAAPALIWTGKGARTGLAIAVALFTAHIAFGFYRLAQ
HHHHHCCCCEEEHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHCC
PAPPSAAPQMAVRVVQPVIDQAKKLDDRERASIFEDHLSLTAAPVQGGGKRPDIVVWPET
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEECCCCCCCCCEEEECCC
SIPFILTDNPDALARIAEVLKDGQILVAGAVRAEDAGAGLPSRYYNSVYVIDDRGQIIGA
CCCEEEECCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHCCEEEEECCCCCEEEC
ADKVHLVPFGEYLPYEDLLTSWGLSSIAASMPGGFSAARMRPVLTLPGGRRLYPMICYEA
CCEEEEEECCCCCCHHHHHHHCCHHHHHHHCCCCCCHHHCCEEEECCCCCCCHHHHHHHH
IFADEVDANARLADVLLNVTNDAWFGDTPGPRQHFHQAQLRAVETGIPMIRAANTGISAV
HHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHH
VDARGVLVLVLGYNYRGVLDTILPGKLPTLTDVPTRSRIFWLSMAILSIVASFSRFGFNI
CCCCCEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEE
RKN
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]