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The map label for this gene is secY [H]

Identifier: 150401829

GI number: 150401829

Start: 1461447

End: 1462778

Strand: Direct

Name: secY [H]

Synonym: Maeo_1407

Alternate gene names: 150401829

Gene position: 1461447-1462778 (Clockwise)

Preceding gene: 150401828

Following gene: 150401831

Centisome position: 93.12

GC content: 35.06

Gene sequence:

>1332_bases
TTGGAAGAATTTCTAAAAAAAATAAGACCAATTCTTGAATATATTCCCGAGGTGCAAAGACCTATACGGGAAATAACATT
TAAAGAAAAATTAAAATGGACGGCTTTGGTCTTAATAGTTTATTTTTTGATGGGAACCATTGACATATATACCGCAGGGG
CAACAATTCCAGCCCAATTTGAATATCTACAAACAATATTTGCATCAAAAATAGGAACATTAATTACGCTAGGTATTGGA
CCTATTGTTACAGCAGGTATTATAATGCAGTTATTGGTAGGTTCTGAGCTTATAAAATTAGATTTATCAAAACCAGAAAA
TAGAGCCTCATTCCAAGGACTTCAAAAATTATTTGGTATATTTTTATGTTTTATGGAAGCAATAATGTTTGTTAGTGTTG
GAGCATTTGGAGCATTATCTGGGAGCACAATGTGGTTAGTAATAGCCCAAGTTGCACTTGGTGCCATATTGGTAATATAT
TTAGACGAAATAGTTTCAAGATATGGTATTGGTTCGGGTATTGGATTGTTTATTGCAGCGGGAGTTTCTCAAACAATATT
TGTTGGGGCTTTTGGGCCTGGCGGGTATCTTTGGAAATTCTTTGATGCCATGGTTCAAGGGGCAATTGGAACAGCATTTG
AGTTTTTACTTCCAATATTGGGAACAATAATAGTTTTCCTAATAGTAGTATATGCTGAAAGTATGCGGGTTGAAATTCCA
CTTGCACACGGTAGAGTTAGGGGTGCAGTTGGAAAATATCCTATAAAATTTATATATGTATCAAATTTGCCGGTAATTCT
TGCAATGGCATTATTTGCAAATGTCCAATTAGTTGGGTTAATGGTGCAAAGTAAATTGGGTTACCCATTACTTGGTAGTT
TTGTAGATGGTAGGGCAGTAAGTGGGATTGCCTATTATTTTGCTACTCCCTATGGATTAACAAGCGTTCTTGCAGACCCG
ATTAGGGCAATAATATATACAATATTAATGATAATATTTTGTATAATATTTGGTATGTTCTGGGTTGAAACATCTGGATT
AGATGCAAAATCCATGGCAAAAAAAATGGGAAGTATGAATATGGCAATTAAAGGATTTAGAAAATCCAATAAATCAATTG
AAAATAGATTAAAAAGATATATATTGCCAATAACTGTAATGAGCTCCGCATTTGTTGGGCTGTTAGCATCGGGTGCAGAT
TTTATGGGGGCATTAGGTGGGGGAACAGGGGTATTACTTACAGTATCTATTGTATATAGAATGTATGAACAGCTTGTTCA
GGAGCAAGTATCGGAGCTCCACCCCGCACTTGGAAAATTCTTGAAAAAATAA

Upstream 100 bases:

>100_bases
TCAATTAGCTAGGGCTCCATGCAGGGAGCTCCTTAACAGGCATCATATATTTATATTATATTTTCATATTTCTATTTAAT
AATTAATATTGGGTGATAAT

Downstream 100 bases:

>100_bases
ATTTTAATTAAAAATATAAATATTTTAATATTTAATATTTAATATTTAATATTTTTAAAATGAATTCCATGAAAATATGA
TGTTTTCAAAGGAAATTATA

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: Protein transport protein SEC61 subunit alpha homolog [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MEEFLKKIRPILEYIPEVQRPIREITFKEKLKWTALVLIVYFLMGTIDIYTAGATIPAQFEYLQTIFASKIGTLITLGIG
PIVTAGIIMQLLVGSELIKLDLSKPENRASFQGLQKLFGIFLCFMEAIMFVSVGAFGALSGSTMWLVIAQVALGAILVIY
LDEIVSRYGIGSGIGLFIAAGVSQTIFVGAFGPGGYLWKFFDAMVQGAIGTAFEFLLPILGTIIVFLIVVYAESMRVEIP
LAHGRVRGAVGKYPIKFIYVSNLPVILAMALFANVQLVGLMVQSKLGYPLLGSFVDGRAVSGIAYYFATPYGLTSVLADP
IRAIIYTILMIIFCIIFGMFWVETSGLDAKSMAKKMGSMNMAIKGFRKSNKSIENRLKRYILPITVMSSAFVGLLASGAD
FMGALGGGTGVLLTVSIVYRMYEQLVQEQVSELHPALGKFLKK

Sequences:

>Translated_443_residues
MEEFLKKIRPILEYIPEVQRPIREITFKEKLKWTALVLIVYFLMGTIDIYTAGATIPAQFEYLQTIFASKIGTLITLGIG
PIVTAGIIMQLLVGSELIKLDLSKPENRASFQGLQKLFGIFLCFMEAIMFVSVGAFGALSGSTMWLVIAQVALGAILVIY
LDEIVSRYGIGSGIGLFIAAGVSQTIFVGAFGPGGYLWKFFDAMVQGAIGTAFEFLLPILGTIIVFLIVVYAESMRVEIP
LAHGRVRGAVGKYPIKFIYVSNLPVILAMALFANVQLVGLMVQSKLGYPLLGSFVDGRAVSGIAYYFATPYGLTSVLADP
IRAIIYTILMIIFCIIFGMFWVETSGLDAKSMAKKMGSMNMAIKGFRKSNKSIENRLKRYILPITVMSSAFVGLLASGAD
FMGALGGGTGVLLTVSIVYRMYEQLVQEQVSELHPALGKFLKK
>Mature_443_residues
MEEFLKKIRPILEYIPEVQRPIREITFKEKLKWTALVLIVYFLMGTIDIYTAGATIPAQFEYLQTIFASKIGTLITLGIG
PIVTAGIIMQLLVGSELIKLDLSKPENRASFQGLQKLFGIFLCFMEAIMFVSVGAFGALSGSTMWLVIAQVALGAILVIY
LDEIVSRYGIGSGIGLFIAAGVSQTIFVGAFGPGGYLWKFFDAMVQGAIGTAFEFLLPILGTIIVFLIVVYAESMRVEIP
LAHGRVRGAVGKYPIKFIYVSNLPVILAMALFANVQLVGLMVQSKLGYPLLGSFVDGRAVSGIAYYFATPYGLTSVLADP
IRAIIYTILMIIFCIIFGMFWVETSGLDAKSMAKKMGSMNMAIKGFRKSNKSIENRLKRYILPITVMSSAFVGLLASGAD
FMGALGGGTGVLLTVSIVYRMYEQLVQEQVSELHPALGKFLKK

Specific function: Involved in protein export. Interacts with secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Homo sapiens, GI7019415, Length=465, Percent_Identity=35.6989247311828, Blast_Score=268, Evalue=9e-72,
Organism=Homo sapiens, GI14589847, Length=465, Percent_Identity=34.1935483870968, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI217330618, Length=464, Percent_Identity=32.7586206896552, Blast_Score=233, Evalue=4e-61,
Organism=Homo sapiens, GI217330616, Length=415, Percent_Identity=33.2530120481928, Blast_Score=221, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17543770, Length=462, Percent_Identity=36.3636363636364, Blast_Score=273, Evalue=1e-73,
Organism=Saccharomyces cerevisiae, GI6323411, Length=461, Percent_Identity=31.6702819956616, Blast_Score=233, Evalue=5e-62,
Organism=Saccharomyces cerevisiae, GI6319760, Length=468, Percent_Identity=24.5726495726496, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI19920826, Length=465, Percent_Identity=35.4838709677419, Blast_Score=265, Evalue=5e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201
- InterPro:   IPR019561 [H]

Pfam domain/function: PF10559 Plug_translocon; PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 48353; Mature: 48353

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS00318 HMG_COA_REDUCTASE_2 ; PS00687 ALDEHYDE_DEHYDR_GLU ; PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEFLKKIRPILEYIPEVQRPIREITFKEKLKWTALVLIVYFLMGTIDIYTAGATIPAQF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
EYLQTIFASKIGTLITLGIGPIVTAGIIMQLLVGSELIKLDLSKPENRASFQGLQKLFGI
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHEEEECCCCCCHHHHHHHHHHHHH
FLCFMEAIMFVSVGAFGALSGSTMWLVIAQVALGAILVIYLDEIVSRYGIGSGIGLFIAA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
GVSQTIFVGAFGPGGYLWKFFDAMVQGAIGTAFEFLLPILGTIIVFLIVVYAESMRVEIP
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
LAHGRVRGAVGKYPIKFIYVSNLPVILAMALFANVQLVGLMVQSKLGYPLLGSFVDGRAV
ECCCHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHH
SGIAYYFATPYGLTSVLADPIRAIIYTILMIIFCIIFGMFWVETSGLDAKSMAKKMGSMN
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHH
MAIKGFRKSNKSIENRLKRYILPITVMSSAFVGLLASGADFMGALGGGTGVLLTVSIVYR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHH
MYEQLVQEQVSELHPALGKFLKK
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEEFLKKIRPILEYIPEVQRPIREITFKEKLKWTALVLIVYFLMGTIDIYTAGATIPAQF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
EYLQTIFASKIGTLITLGIGPIVTAGIIMQLLVGSELIKLDLSKPENRASFQGLQKLFGI
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHEEEECCCCCCHHHHHHHHHHHHH
FLCFMEAIMFVSVGAFGALSGSTMWLVIAQVALGAILVIYLDEIVSRYGIGSGIGLFIAA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
GVSQTIFVGAFGPGGYLWKFFDAMVQGAIGTAFEFLLPILGTIIVFLIVVYAESMRVEIP
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
LAHGRVRGAVGKYPIKFIYVSNLPVILAMALFANVQLVGLMVQSKLGYPLLGSFVDGRAV
ECCCHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHH
SGIAYYFATPYGLTSVLADPIRAIIYTILMIIFCIIFGMFWVETSGLDAKSMAKKMGSMN
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHH
MAIKGFRKSNKSIENRLKRYILPITVMSSAFVGLLASGADFMGALGGGTGVLLTVSIVYR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHH
MYEQLVQEQVSELHPALGKFLKK
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1764515 [H]