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The map label for this gene is dcp [H]

Identifier: 150008235

GI number: 150008235

Start: 1874610

End: 1876769

Strand: Reverse

Name: dcp [H]

Synonym: BDI_1601

Alternate gene names: 150008235

Gene position: 1876769-1874610 (Counterclockwise)

Preceding gene: 150008236

Following gene: 150008234

Centisome position: 39.01

GC content: 48.19

Gene sequence:

>2160_bases
ATGAAACAATTAATTATGGCAGCAGGATTAGCCGTTATGCTTACTGCCTGCGGTACTTCCGAAAAGAAGACCGTGGAGGG
TGAGAACCCGTTCTTTGCGGAATATACCACCCCGTTTGGAGTTCCACCTTTTGATCAAATCAAGTTCGAGCACTACAAAC
CGGCCCTATTGCAAGGCATGGAAGAGGGACGCAAGGAGATCGAGGCGATCGTGAATAACCCGGAGGAGCCGACGTTCGAG
AATACGATTGTCGCTTTGGATGAGCAGGGTGCGTTGCTTCGGAAGGTCCAGATCGTTTTCGGTGGACAGAATAGCGTGAA
TACGAATGATGAGATGCAGGCGTTAAGCCGTGAGATGTCGCCGCTATTGTCAAAATATAGTGATGATATCAACTTGAATC
CGAAATTATTCGCTCGTGTGAAGGCGGTATACGATAAGAAGGATGAGTTGGGTCTCGATAAGGAGCAAATGAAGTTATTG
GAGGAGACTTATAAGGACTTCGTTCGGGGTGGCGCTAATCTTTCCGCTGAGGATCAGGCTAAATTGCGTGAGTTGAATAG
CAAGATCTCCATGCTACAGCTTACTTTCGGACAGAATATGCTGAAAGAGACGAACGCTTTTAAATTGGTGATCGACAAGC
AGGAGGATCTTTCCGGTCTGCCCGAGACCTTGATCGCTAACGCCGCTCAAGCGGCTAAGGATGCCGGGATGGAAGGCAAA
TGGGTATTTACCTTGCAGAACCCGAGCGTGATGCCGTTCTTGCAATATTCCGATAAACGTGAGTTGCGTGAGAAGATGTT
CAACGCTTATATCAACCGTGGTAATAATAATAATGAGAACGATAACAAGGAAGTGGTTCGTGATTTGGTTGCCGCTCGTT
TGGCGAAAGCGAAGTTGATGGGCTATGATGATTACGCTTCTTTCGTGTTGGAGGATCGTATGGCGAAAAGCTCGGATAAG
GTTTATCAATTGTTAGATGAGGTTTGGAAGCCTGCTTTGGCGAAAGCGAAAGAGGAATTGGCCGATATAAACGCCGAGAT
CAAGAAAGAAGGCGGCAATTTCGAGGCCGAGGGCTGGGATTGGCGTTATTATTTCGAGAAGGCCAAGAAGGCTAAATTCA
ATTTGGATGAGAATGAGGTTCGTCCTTACTTGAAGTTGGATAATGTTCGTGAGGGTGCTTTCTATGTAGCTAATAAGTTA
TATGGTATCACGTTCACCCCGATCCGTAATATTCCGTTGCCTTATCCGGAAGCGCAGGCTTTTGAGTGCAAAGATAAGGA
TGGCTCTCATTTGGGCGTTATTTATTTCGATTTCTTCCCTCGTGCTAGCAAGCGTGGTGGTGCGTGGTGTGGTTCTTATC
GTCCGCAGGCTTATAAGGATGGCAAGCGTGTGGCTCCGGTCGTAACGATCGTTTGTAACTTTAGCCAGCCCGCTCCGGGA
CAACCTGCGTTGTTGAGCGCTGATGAGGCGAATACATTGTTCCATGAGTTCGGTCATGGTTTGCACGGCTTGTTCCGTGA
CGTGCATTACTCCGGTGTTTCCGGTGTTCCTCGTGATTTCGTGGAGTTGCCTTCACAGGTTATGGAGCATTGGGTATTCG
AGCCGGAAGTATTGAAGGTGTACGCTAAGCATTATCAGACCGGCGAGGTGATCCCGGCCGAGTTGATCGAGAAGTTGGAT
AAGAGCGGTAAGTACGGACAAGGTTTCGCTACGACGGAGTATCTGGCGGCTTCTTATCTGGATATGGATTTCCATGCGAT
CAGTGGTGACGCTGCGGATAAGAAGGTGATCAAGTTCGTTGACCAGACGAATAATGTTCCGGCCAACTTGAACGTGATGG
ATTTCGAGCAACAGACGTTAGGCCGTCGTGGTTTGCTGAAACAAATCCCTTCCCGTTACCGTACGACTTACTTCAACCAT
ACGATGGGTGGCGGCTACACCGCCGGCTATTATAGCTACATCTGGGCTGAGGTATTGGATTGCGACGCTTTCGAGGCATT
CAAGGAAACCGGCGACATCTTTAATCAAGAATGTGCCGATAAATTCCGTAAATATGTCTTGACCCCGGGCGGTATCGACG
ACGCTATGGATATGTACAAGAATTTCCGTGGCAAGGAACCGGGTACGGATCCGTTGCTGAAGAATAGAGGACTGAAATAA

Upstream 100 bases:

>100_bases
ATTTCCGTGGCAAACAACCTAGCATCGATCCGCTGTTGGAGAACAGAGGGCTAAAATGAGCAGAACAATTTATAACTCAT
AAATCAAAAAATCAGTAAAG

Downstream 100 bases:

>100_bases
TCTAGAAATGGAGATTTTATAAAGGCGGACCGGTTGGTTCGCCTTTTTTTGTATATGCTCAACCTCCCGGATCTGTATTA
CATTTGCTAAGTTTTATCAC

Product: peptidyl-dipeptidase

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 719; Mature: 719

Protein sequence:

>719_residues
MKQLIMAAGLAVMLTACGTSEKKTVEGENPFFAEYTTPFGVPPFDQIKFEHYKPALLQGMEEGRKEIEAIVNNPEEPTFE
NTIVALDEQGALLRKVQIVFGGQNSVNTNDEMQALSREMSPLLSKYSDDINLNPKLFARVKAVYDKKDELGLDKEQMKLL
EETYKDFVRGGANLSAEDQAKLRELNSKISMLQLTFGQNMLKETNAFKLVIDKQEDLSGLPETLIANAAQAAKDAGMEGK
WVFTLQNPSVMPFLQYSDKRELREKMFNAYINRGNNNNENDNKEVVRDLVAARLAKAKLMGYDDYASFVLEDRMAKSSDK
VYQLLDEVWKPALAKAKEELADINAEIKKEGGNFEAEGWDWRYYFEKAKKAKFNLDENEVRPYLKLDNVREGAFYVANKL
YGITFTPIRNIPLPYPEAQAFECKDKDGSHLGVIYFDFFPRASKRGGAWCGSYRPQAYKDGKRVAPVVTIVCNFSQPAPG
QPALLSADEANTLFHEFGHGLHGLFRDVHYSGVSGVPRDFVELPSQVMEHWVFEPEVLKVYAKHYQTGEVIPAELIEKLD
KSGKYGQGFATTEYLAASYLDMDFHAISGDAADKKVIKFVDQTNNVPANLNVMDFEQQTLGRRGLLKQIPSRYRTTYFNH
TMGGGYTAGYYSYIWAEVLDCDAFEAFKETGDIFNQECADKFRKYVLTPGGIDDAMDMYKNFRGKEPGTDPLLKNRGLK

Sequences:

>Translated_719_residues
MKQLIMAAGLAVMLTACGTSEKKTVEGENPFFAEYTTPFGVPPFDQIKFEHYKPALLQGMEEGRKEIEAIVNNPEEPTFE
NTIVALDEQGALLRKVQIVFGGQNSVNTNDEMQALSREMSPLLSKYSDDINLNPKLFARVKAVYDKKDELGLDKEQMKLL
EETYKDFVRGGANLSAEDQAKLRELNSKISMLQLTFGQNMLKETNAFKLVIDKQEDLSGLPETLIANAAQAAKDAGMEGK
WVFTLQNPSVMPFLQYSDKRELREKMFNAYINRGNNNNENDNKEVVRDLVAARLAKAKLMGYDDYASFVLEDRMAKSSDK
VYQLLDEVWKPALAKAKEELADINAEIKKEGGNFEAEGWDWRYYFEKAKKAKFNLDENEVRPYLKLDNVREGAFYVANKL
YGITFTPIRNIPLPYPEAQAFECKDKDGSHLGVIYFDFFPRASKRGGAWCGSYRPQAYKDGKRVAPVVTIVCNFSQPAPG
QPALLSADEANTLFHEFGHGLHGLFRDVHYSGVSGVPRDFVELPSQVMEHWVFEPEVLKVYAKHYQTGEVIPAELIEKLD
KSGKYGQGFATTEYLAASYLDMDFHAISGDAADKKVIKFVDQTNNVPANLNVMDFEQQTLGRRGLLKQIPSRYRTTYFNH
TMGGGYTAGYYSYIWAEVLDCDAFEAFKETGDIFNQECADKFRKYVLTPGGIDDAMDMYKNFRGKEPGTDPLLKNRGLK
>Mature_719_residues
MKQLIMAAGLAVMLTACGTSEKKTVEGENPFFAEYTTPFGVPPFDQIKFEHYKPALLQGMEEGRKEIEAIVNNPEEPTFE
NTIVALDEQGALLRKVQIVFGGQNSVNTNDEMQALSREMSPLLSKYSDDINLNPKLFARVKAVYDKKDELGLDKEQMKLL
EETYKDFVRGGANLSAEDQAKLRELNSKISMLQLTFGQNMLKETNAFKLVIDKQEDLSGLPETLIANAAQAAKDAGMEGK
WVFTLQNPSVMPFLQYSDKRELREKMFNAYINRGNNNNENDNKEVVRDLVAARLAKAKLMGYDDYASFVLEDRMAKSSDK
VYQLLDEVWKPALAKAKEELADINAEIKKEGGNFEAEGWDWRYYFEKAKKAKFNLDENEVRPYLKLDNVREGAFYVANKL
YGITFTPIRNIPLPYPEAQAFECKDKDGSHLGVIYFDFFPRASKRGGAWCGSYRPQAYKDGKRVAPVVTIVCNFSQPAPG
QPALLSADEANTLFHEFGHGLHGLFRDVHYSGVSGVPRDFVELPSQVMEHWVFEPEVLKVYAKHYQTGEVIPAELIEKLD
KSGKYGQGFATTEYLAASYLDMDFHAISGDAADKKVIKFVDQTNNVPANLNVMDFEQQTLGRRGLLKQIPSRYRTTYFNH
TMGGGYTAGYYSYIWAEVLDCDAFEAFKETGDIFNQECADKFRKYVLTPGGIDDAMDMYKNFRGKEPGTDPLLKNRGLK

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=656, Percent_Identity=28.5060975609756, Blast_Score=288, Evalue=1e-77,
Organism=Homo sapiens, GI14149738, Length=656, Percent_Identity=30.4878048780488, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI156105687, Length=690, Percent_Identity=24.9275362318841, Blast_Score=158, Evalue=2e-38,
Organism=Escherichia coli, GI1787819, Length=694, Percent_Identity=40.3458213256484, Blast_Score=526, Evalue=1e-150,
Organism=Escherichia coli, GI1789913, Length=692, Percent_Identity=33.8150289017341, Blast_Score=398, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI71999758, Length=586, Percent_Identity=19.1126279863481, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32565901, Length=583, Percent_Identity=19.8970840480274, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319793, Length=674, Percent_Identity=28.9317507418398, Blast_Score=237, Evalue=4e-63,
Organism=Saccharomyces cerevisiae, GI6322715, Length=721, Percent_Identity=24.2718446601942, Blast_Score=134, Evalue=4e-32,
Organism=Drosophila melanogaster, GI21356111, Length=715, Percent_Identity=21.5384615384615, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI20129717, Length=705, Percent_Identity=23.1205673758865, Blast_Score=142, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 81273; Mature: 81273

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLIMAAGLAVMLTACGTSEKKTVEGENPFFAEYTTPFGVPPFDQIKFEHYKPALLQGM
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCHHHCCHHHCCHHHHHHH
EEGRKEIEAIVNNPEEPTFENTIVALDEQGALLRKVQIVFGGQNSVNTNDEMQALSREMS
HHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHH
PLLSKYSDDINLNPKLFARVKAVYDKKDELGLDKEQMKLLEETYKDFVRGGANLSAEDQA
HHHHHCCCCCCCCHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHH
KLRELNSKISMLQLTFGQNMLKETNAFKLVIDKQEDLSGLPETLIANAAQAAKDAGMEGK
HHHHHHHHHHHEEEHHHHHHHHCCCCEEEEEECCHHHCCCCHHHHHHHHHHHHHCCCCCE
WVFTLQNPSVMPFLQYSDKRELREKMFNAYINRGNNNNENDNKEVVRDLVAARLAKAKLM
EEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GYDDYASFVLEDRMAKSSDKVYQLLDEVWKPALAKAKEELADINAEIKKEGGNFEAEGWD
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCC
WRYYFEKAKKAKFNLDENEVRPYLKLDNVREGAFYVANKLYGITFTPIRNIPLPYPEAQA
HHHHHHHHHHCCCCCCHHHCCCCEEECCCCCCHHHHHHHHCCEEECCCCCCCCCCCCCCC
FECKDKDGSHLGVIYFDFFPRASKRGGAWCGSYRPQAYKDGKRVAPVVTIVCNFSQPAPG
EECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHCCCCCCCEEEEEEEECCCCCCC
QPALLSADEANTLFHEFGHGLHGLFRDVHYSGVSGVPRDFVELPSQVMEHWVFEPEVLKV
CCCEEECCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
YAKHYQTGEVIPAELIEKLDKSGKYGQGFATTEYLAASYLDMDFHAISGDAADKKVIKFV
HHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCHHHHHHHHH
DQTNNVPANLNVMDFEQQTLGRRGLLKQIPSRYRTTYFNHTMGGGYTAGYYSYIWAEVLD
HHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHC
CDAFEAFKETGDIFNQECADKFRKYVLTPGGIDDAMDMYKNFRGKEPGTDPLLKNRGLK
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHCCCCC
>Mature Secondary Structure
MKQLIMAAGLAVMLTACGTSEKKTVEGENPFFAEYTTPFGVPPFDQIKFEHYKPALLQGM
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCHHHCCHHHCCHHHHHHH
EEGRKEIEAIVNNPEEPTFENTIVALDEQGALLRKVQIVFGGQNSVNTNDEMQALSREMS
HHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHH
PLLSKYSDDINLNPKLFARVKAVYDKKDELGLDKEQMKLLEETYKDFVRGGANLSAEDQA
HHHHHCCCCCCCCHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHH
KLRELNSKISMLQLTFGQNMLKETNAFKLVIDKQEDLSGLPETLIANAAQAAKDAGMEGK
HHHHHHHHHHHEEEHHHHHHHHCCCCEEEEEECCHHHCCCCHHHHHHHHHHHHHCCCCCE
WVFTLQNPSVMPFLQYSDKRELREKMFNAYINRGNNNNENDNKEVVRDLVAARLAKAKLM
EEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GYDDYASFVLEDRMAKSSDKVYQLLDEVWKPALAKAKEELADINAEIKKEGGNFEAEGWD
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCC
WRYYFEKAKKAKFNLDENEVRPYLKLDNVREGAFYVANKLYGITFTPIRNIPLPYPEAQA
HHHHHHHHHHCCCCCCHHHCCCCEEECCCCCCHHHHHHHHCCEEECCCCCCCCCCCCCCC
FECKDKDGSHLGVIYFDFFPRASKRGGAWCGSYRPQAYKDGKRVAPVVTIVCNFSQPAPG
EECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHCCCCCCCEEEEEEEECCCCCCC
QPALLSADEANTLFHEFGHGLHGLFRDVHYSGVSGVPRDFVELPSQVMEHWVFEPEVLKV
CCCEEECCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
YAKHYQTGEVIPAELIEKLDKSGKYGQGFATTEYLAASYLDMDFHAISGDAADKKVIKFV
HHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCHHHHHHHHH
DQTNNVPANLNVMDFEQQTLGRRGLLKQIPSRYRTTYFNHTMGGGYTAGYYSYIWAEVLD
HHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHC
CDAFEAFKETGDIFNQECADKFRKYVLTPGGIDDAMDMYKNFRGKEPGTDPLLKNRGLK
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]