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The map label for this gene is dcp [H]

Identifier: 150008236

GI number: 150008236

Start: 1876811

End: 1878931

Strand: Reverse

Name: dcp [H]

Synonym: BDI_1602

Alternate gene names: 150008236

Gene position: 1878931-1876811 (Counterclockwise)

Preceding gene: 150008238

Following gene: 150008235

Centisome position: 39.05

GC content: 48.99

Gene sequence:

>2121_bases
ATGAATAAAACGCTTATGGCCGCAGGTTTAGCGGTTATTTTGGGAGCTTGTTCCTCCTCAAAGAAAAGCGATGTAGCGGA
AGGCGCTACACCCAATCCGTTTTTTGCGGAGTATACGACACCGTTCGGGGTGCCTCCGTTTGACCAAATAGAGGTGGCTC
ATTACAAGCCGGCTCTTTTGAAAGGCATGGAAGAGCAGTCGAAGGAGATTGAGGCGATCGTGGCAAATCCGGATGCGCCG
ACATTCGAGAATACGATCGTGGCCTTAGACCAAAGTGGCGAGTTGCTTACTAAAGTAATGTATGCTTTCGGTGGCCAATC
CAGTGTGAATACCACGGACGAGATCCAAGAGCTCGAACGTGAGCTTTATCCCCTTTTATCCAAACATTCGGATGATATCA
GCTTAAATCCCAAGCTTTTCGCCCGGGTGAAATCCGTATATGAGAATCAGGCGAGCTTCCATCTGGATAAGGAACAGAAG
AAGCTGTTGGAGGAAACCTATAAAAGTTTTGTCCGGGGAGGAGCCAATCTGCCGGAGGATAAGCAGGCGAAGTTGCGTGA
GCTGAACGAGAAGATATCCATGCTCCAACTTACTTTCGGACAGAATACCCTGAAAGAGACCAACGATTTCCAATTAGTGA
TCGATAATAAAGAGGACTTATCCGGTCTGCCGGAAGACGTGATCGTCAAGGCGGCGCAAACGGCCCAAGAGAATGGTCTG
GATGGTAAGTGGGTGTTTACCCTCCATAATCCGAGCGTGATGCCTTTCCTTCAATACGCCGATAAGCGTGATTTGCGTGA
GAAGATCTTCAAGGCGTATACGAATCGTGGCAACAATAATAATGAGAATGATAATAAGGAGGTCGTTAAGCAGCTGGTTG
CCGCTCGTCTGGAGAAAGCCCGATTGATGGGATATGAGGATTATGCCGCTTTCGTATTGGAAGAGAATATGGCGAAGAAC
GAGAAGAACGTGTACGACTTGCTTGATAAAATCTGGCCATCTGCCTTGGCGAAAGCGAAAGAGGAATTGGCCGATATCAA
CGCCGAGATCAAGAAGGAAGGCGGTAATTACGAGGCCGAGGGCTGGGACTGGCGTTATTATTTCGAGAAAGCCAAGAAAG
CGAAATATAACTTGGACGAGAACGAGATGCGTCCTTATTTTGAGTTGGGACATGTACGTGAGGGCATCTTCTATGTAGCC
AATAAATTATACGGTATCACGTTTACCGAGATCAAGGACATCCCGAAACCGGACCCCGACGCTCTCGCTTTCGAGTGCAA
GGATAAAGATGGTACGCATCTGGGCGTATTGTATATGGATTTCTTTACCCGCCCGGGCAAAGGAGGTGGCGCATGGTGCG
GCGGTTACCGTTCACAAACGTATAAGGATGGGAAACGGGTAGCCCCGGTGGTTACTACCGTATTTAATTTCAGCAAACCG
GCGGAGGGACAACCGGCGCTTTTGACGGCCGACGAGACCGAGACCGTATTCCATGAGTTCGGTCATGCCTTGCACGGTTT
ATTCTGCGATGTTCATTATTATGGCGTGTCCGACGTGCCTCGTGACTTTGTGGAGCTACCTTCGCAAGTCGATGAGCATT
GGGCCGTTGAGCCGGAGGTATTGAAAGTGTACGCTAAACATTACCAGACCGGCGAGGTAATACCGCAAGCCCTTGTAGAC
AAGATGATCAAGAGTGGCAAGTATGGACAAGGCTTCGCTACGACGGAGTATCTGGCCGCCTCTTATCTGGATATGGATTA
TCATGTATTGAAAGAGATCCCTGCCGATTTGGATATCGAGAAATTTGAGGCGAAGGTCTTGGGCGATCGTGGTCTGATCC
GTCAGATTCCGTCTCGCTATCGCTCCACTTATTTCGGACATACGATGGAAGGTGGATATACAGCCGGTTATTATAGTTAT
ATCTGGGCGGAAGTGTTGGATTGCGACGCTTTCCAAGCTTATAAGGAGACGGGTAATATCTTCAACCCGGAGGTTGCCTC
TAAATTCCGTAAATACGTACTGACCCCGGGCGGCATCGACGACGCTATGGACATGTACGTGAATTTCCGTGGCAAACAAC
CTAGCATCGATCCGCTGTTGGAGAACAGAGGGCTAAAATGA

Upstream 100 bases:

>100_bases
GAAAATCTTTTTCCGGATTCTAAATAATAACAATTTGAAATAGAATTGTAACGCAAAACTTCGTTATCTTTGTCCATTGT
AATTCTAATATAACAATGGC

Downstream 100 bases:

>100_bases
GCAGAACAATTTATAACTCATAAATCAAAAAATCAGTAAAGATGAAACAATTAATTATGGCAGCAGGATTAGCCGTTATG
CTTACTGCCTGCGGTACTTC

Product: peptidyl-dipeptidase

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 706; Mature: 706

Protein sequence:

>706_residues
MNKTLMAAGLAVILGACSSSKKSDVAEGATPNPFFAEYTTPFGVPPFDQIEVAHYKPALLKGMEEQSKEIEAIVANPDAP
TFENTIVALDQSGELLTKVMYAFGGQSSVNTTDEIQELERELYPLLSKHSDDISLNPKLFARVKSVYENQASFHLDKEQK
KLLEETYKSFVRGGANLPEDKQAKLRELNEKISMLQLTFGQNTLKETNDFQLVIDNKEDLSGLPEDVIVKAAQTAQENGL
DGKWVFTLHNPSVMPFLQYADKRDLREKIFKAYTNRGNNNNENDNKEVVKQLVAARLEKARLMGYEDYAAFVLEENMAKN
EKNVYDLLDKIWPSALAKAKEELADINAEIKKEGGNYEAEGWDWRYYFEKAKKAKYNLDENEMRPYFELGHVREGIFYVA
NKLYGITFTEIKDIPKPDPDALAFECKDKDGTHLGVLYMDFFTRPGKGGGAWCGGYRSQTYKDGKRVAPVVTTVFNFSKP
AEGQPALLTADETETVFHEFGHALHGLFCDVHYYGVSDVPRDFVELPSQVDEHWAVEPEVLKVYAKHYQTGEVIPQALVD
KMIKSGKYGQGFATTEYLAASYLDMDYHVLKEIPADLDIEKFEAKVLGDRGLIRQIPSRYRSTYFGHTMEGGYTAGYYSY
IWAEVLDCDAFQAYKETGNIFNPEVASKFRKYVLTPGGIDDAMDMYVNFRGKQPSIDPLLENRGLK

Sequences:

>Translated_706_residues
MNKTLMAAGLAVILGACSSSKKSDVAEGATPNPFFAEYTTPFGVPPFDQIEVAHYKPALLKGMEEQSKEIEAIVANPDAP
TFENTIVALDQSGELLTKVMYAFGGQSSVNTTDEIQELERELYPLLSKHSDDISLNPKLFARVKSVYENQASFHLDKEQK
KLLEETYKSFVRGGANLPEDKQAKLRELNEKISMLQLTFGQNTLKETNDFQLVIDNKEDLSGLPEDVIVKAAQTAQENGL
DGKWVFTLHNPSVMPFLQYADKRDLREKIFKAYTNRGNNNNENDNKEVVKQLVAARLEKARLMGYEDYAAFVLEENMAKN
EKNVYDLLDKIWPSALAKAKEELADINAEIKKEGGNYEAEGWDWRYYFEKAKKAKYNLDENEMRPYFELGHVREGIFYVA
NKLYGITFTEIKDIPKPDPDALAFECKDKDGTHLGVLYMDFFTRPGKGGGAWCGGYRSQTYKDGKRVAPVVTTVFNFSKP
AEGQPALLTADETETVFHEFGHALHGLFCDVHYYGVSDVPRDFVELPSQVDEHWAVEPEVLKVYAKHYQTGEVIPQALVD
KMIKSGKYGQGFATTEYLAASYLDMDYHVLKEIPADLDIEKFEAKVLGDRGLIRQIPSRYRSTYFGHTMEGGYTAGYYSY
IWAEVLDCDAFQAYKETGNIFNPEVASKFRKYVLTPGGIDDAMDMYVNFRGKQPSIDPLLENRGLK
>Mature_706_residues
MNKTLMAAGLAVILGACSSSKKSDVAEGATPNPFFAEYTTPFGVPPFDQIEVAHYKPALLKGMEEQSKEIEAIVANPDAP
TFENTIVALDQSGELLTKVMYAFGGQSSVNTTDEIQELERELYPLLSKHSDDISLNPKLFARVKSVYENQASFHLDKEQK
KLLEETYKSFVRGGANLPEDKQAKLRELNEKISMLQLTFGQNTLKETNDFQLVIDNKEDLSGLPEDVIVKAAQTAQENGL
DGKWVFTLHNPSVMPFLQYADKRDLREKIFKAYTNRGNNNNENDNKEVVKQLVAARLEKARLMGYEDYAAFVLEENMAKN
EKNVYDLLDKIWPSALAKAKEELADINAEIKKEGGNYEAEGWDWRYYFEKAKKAKYNLDENEMRPYFELGHVREGIFYVA
NKLYGITFTEIKDIPKPDPDALAFECKDKDGTHLGVLYMDFFTRPGKGGGAWCGGYRSQTYKDGKRVAPVVTTVFNFSKP
AEGQPALLTADETETVFHEFGHALHGLFCDVHYYGVSDVPRDFVELPSQVDEHWAVEPEVLKVYAKHYQTGEVIPQALVD
KMIKSGKYGQGFATTEYLAASYLDMDYHVLKEIPADLDIEKFEAKVLGDRGLIRQIPSRYRSTYFGHTMEGGYTAGYYSY
IWAEVLDCDAFQAYKETGNIFNPEVASKFRKYVLTPGGIDDAMDMYVNFRGKQPSIDPLLENRGLK

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=636, Percent_Identity=29.2452830188679, Blast_Score=287, Evalue=2e-77,
Organism=Homo sapiens, GI14149738, Length=637, Percent_Identity=30.6122448979592, Blast_Score=274, Evalue=3e-73,
Organism=Homo sapiens, GI156105687, Length=678, Percent_Identity=25.6637168141593, Blast_Score=166, Evalue=6e-41,
Organism=Escherichia coli, GI1787819, Length=680, Percent_Identity=41.4705882352941, Blast_Score=539, Evalue=1e-154,
Organism=Escherichia coli, GI1789913, Length=678, Percent_Identity=34.3657817109145, Blast_Score=397, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI32565901, Length=549, Percent_Identity=20.7650273224044, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71999758, Length=576, Percent_Identity=19.4444444444444, Blast_Score=76, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319793, Length=622, Percent_Identity=30.7073954983923, Blast_Score=225, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6322715, Length=724, Percent_Identity=24.3093922651934, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356111, Length=568, Percent_Identity=23.5915492957746, Blast_Score=149, Evalue=6e-36,
Organism=Drosophila melanogaster, GI20129717, Length=412, Percent_Identity=27.6699029126214, Blast_Score=143, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 79789; Mature: 79789

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTLMAAGLAVILGACSSSKKSDVAEGATPNPFFAEYTTPFGVPPFDQIEVAHYKPALL
CCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEECCCCCCCCCCCCEEHHHCCHHHH
KGMEEQSKEIEAIVANPDAPTFENTIVALDQSGELLTKVMYAFGGQSSVNTTDEIQELER
HCHHHHHCCEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHH
ELYPLLSKHSDDISLNPKLFARVKSVYENQASFHLDKEQKKLLEETYKSFVRGGANLPED
HHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCH
KQAKLRELNEKISMLQLTFGQNTLKETNDFQLVIDNKEDLSGLPEDVIVKAAQTAQENGL
HHHHHHHHHHHHHHHEEECCCHHHCCCCCEEEEECCCHHCCCCCHHHHHHHHHHHHHCCC
DGKWVFTLHNPSVMPFLQYADKRDLREKIFKAYTNRGNNNNENDNKEVVKQLVAARLEKA
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
RLMGYEDYAAFVLEENMAKNEKNVYDLLDKIWPSALAKAKEELADINAEIKKEGGNYEAE
HHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCC
GWDWRYYFEKAKKAKYNLDENEMRPYFELGHVREGIFYVANKLYGITFTEIKDIPKPDPD
CCCHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCC
ALAFECKDKDGTHLGVLYMDFFTRPGKGGGAWCGGYRSQTYKDGKRVAPVVTTVFNFSKP
CEEEEECCCCCCEEEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
AEGQPALLTADETETVFHEFGHALHGLFCDVHYYGVSDVPRDFVELPSQVDEHWAVEPEV
CCCCCEEEECCCHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHCCCCHHH
LKVYAKHYQTGEVIPQALVDKMIKSGKYGQGFATTEYLAASYLDMDYHVLKEIPADLDIE
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCHH
KFEAKVLGDRGLIRQIPSRYRSTYFGHTMEGGYTAGYYSYIWAEVLDCDAFQAYKETGNI
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCC
FNPEVASKFRKYVLTPGGIDDAMDMYVNFRGKQPSIDPLLENRGLK
CCHHHHHHHHHHCCCCCCCHHHHHHHEEECCCCCCCCHHHHCCCCC
>Mature Secondary Structure
MNKTLMAAGLAVILGACSSSKKSDVAEGATPNPFFAEYTTPFGVPPFDQIEVAHYKPALL
CCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEECCCCCCCCCCCCEEHHHCCHHHH
KGMEEQSKEIEAIVANPDAPTFENTIVALDQSGELLTKVMYAFGGQSSVNTTDEIQELER
HCHHHHHCCEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHH
ELYPLLSKHSDDISLNPKLFARVKSVYENQASFHLDKEQKKLLEETYKSFVRGGANLPED
HHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCH
KQAKLRELNEKISMLQLTFGQNTLKETNDFQLVIDNKEDLSGLPEDVIVKAAQTAQENGL
HHHHHHHHHHHHHHHEEECCCHHHCCCCCEEEEECCCHHCCCCCHHHHHHHHHHHHHCCC
DGKWVFTLHNPSVMPFLQYADKRDLREKIFKAYTNRGNNNNENDNKEVVKQLVAARLEKA
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
RLMGYEDYAAFVLEENMAKNEKNVYDLLDKIWPSALAKAKEELADINAEIKKEGGNYEAE
HHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCC
GWDWRYYFEKAKKAKYNLDENEMRPYFELGHVREGIFYVANKLYGITFTEIKDIPKPDPD
CCCHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCC
ALAFECKDKDGTHLGVLYMDFFTRPGKGGGAWCGGYRSQTYKDGKRVAPVVTTVFNFSKP
CEEEEECCCCCCEEEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
AEGQPALLTADETETVFHEFGHALHGLFCDVHYYGVSDVPRDFVELPSQVDEHWAVEPEV
CCCCCEEEECCCHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHCCCCHHH
LKVYAKHYQTGEVIPQALVDKMIKSGKYGQGFATTEYLAASYLDMDYHVLKEIPADLDIE
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCHH
KFEAKVLGDRGLIRQIPSRYRSTYFGHTMEGGYTAGYYSYIWAEVLDCDAFQAYKETGNI
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCC
FNPEVASKFRKYVLTPGGIDDAMDMYVNFRGKQPSIDPLLENRGLK
CCHHHHHHHHHHCCCCCCCHHHHHHHEEECCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]