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The map label for this gene is gcp

Identifier: 150005784

GI number: 150005784

Start: 4109196

End: 4110215

Strand: Direct

Name: gcp

Synonym: BVU_3277

Alternate gene names: 150005784

Gene position: 4109196-4110215 (Clockwise)

Preceding gene: 150005783

Following gene: 150005785

Centisome position: 79.59

GC content: 43.92

Gene sequence:

>1020_bases
ATGGATACAATTATATTAGGTATAGAATCTTCCTGTGACGACACATCAGCCGCAGTTATCAAGAATGGCGTATTGTTGTC
CAACGTAGTGTCCAGCCAGGCTGTTCACGAAGCTTACGGAGGGGTGGTTCCCGAATTGGCGTCACGTGCCCATCAACAAA
ACATTGTACCGGTGGTGCACGAAGCCTTAAAAAGGGCAGGAGTTACCAAGGAGCAACTAAGCGCCGTTGCATTCACCCGA
GGACCCGGCTTGATGGGATCATTACTGGTCGGAGTATCTTTTGCGAAAGGTTTCGCACGTTCATTGAATATACCAATGAT
TGATGTTAACCACCTGCAAGCCCATGTGTTAGCCCATTTCATTAAAGAATCGGAAGAAGACAACAACCAACCTAAATTCC
CTTTCTTGTGCCTGCTGGTGTCAGGAGGAAACTCACAGATAATATTGGTAAAGGCCTATAATGACATGGAAGTTTTGGGA
CAAACTATTGACGATGCAGCAGGAGAAGCTATCGACAAATGTTCTAAAGTAATGGGCTTAGGTTATCCCGGAGGTCCTAT
CATTGATAAACTGGCACGTCAAGGCAATCCAAAAGCGTTCACTTTCAGTAAACCACATATTCCGGACTATAACTATAGTT
TCAGCGGATTAAAGACTTCTTTCCTATACTCTTTGCGTGACTGGTTGAAAGAAGATCCCGATTTCATCGAACATCATAAA
AACGACTTGGCTGCTTCATTGGAAGCGACCATTGTAGATATTTTGATGGACAAGCTGAGAAAAGCAGCCAAAAATCTCAA
GATAAATGAAGTGGCAGTAGCCGGAGGGGTATCAGCCAACAACGGGCTTCGTAACTCATTCCGCGAGCATGCCGGGAAAT
ATGGTTGGAATATCTATATCCCGAAGTTCAGCTTTACTACGGATAATGCCGCAATGATCGCAATTACCGGTTATTACAAG
TATCTGGACAATGATTTTTGCACTATAGACAAGCCCGCTTATTCACGGGTAACTATTTAA

Upstream 100 bases:

>100_bases
AAGACGAACAGCCGTCTGCACAGTGGGAACATACTTTCGTTATGACAGATAACGGACTTGAAATTCTGACACATTAATAT
ATATAATAAGGTATAGAAAT

Downstream 100 bases:

>100_bases
TATTAAAAAACCGTTTTCAACATGTCAGTAGAAGGTAAATTTTTAAGTAAAGAGATTAACGATTTGTTTTGGAGAGAGGG
CCTGACACTCGTTACTGCCG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MDTIILGIESSCDDTSAAVIKNGVLLSNVVSSQAVHEAYGGVVPELASRAHQQNIVPVVHEALKRAGVTKEQLSAVAFTR
GPGLMGSLLVGVSFAKGFARSLNIPMIDVNHLQAHVLAHFIKESEEDNNQPKFPFLCLLVSGGNSQIILVKAYNDMEVLG
QTIDDAAGEAIDKCSKVMGLGYPGGPIIDKLARQGNPKAFTFSKPHIPDYNYSFSGLKTSFLYSLRDWLKEDPDFIEHHK
NDLAASLEATIVDILMDKLRKAAKNLKINEVAVAGGVSANNGLRNSFREHAGKYGWNIYIPKFSFTTDNAAMIAITGYYK
YLDNDFCTIDKPAYSRVTI

Sequences:

>Translated_339_residues
MDTIILGIESSCDDTSAAVIKNGVLLSNVVSSQAVHEAYGGVVPELASRAHQQNIVPVVHEALKRAGVTKEQLSAVAFTR
GPGLMGSLLVGVSFAKGFARSLNIPMIDVNHLQAHVLAHFIKESEEDNNQPKFPFLCLLVSGGNSQIILVKAYNDMEVLG
QTIDDAAGEAIDKCSKVMGLGYPGGPIIDKLARQGNPKAFTFSKPHIPDYNYSFSGLKTSFLYSLRDWLKEDPDFIEHHK
NDLAASLEATIVDILMDKLRKAAKNLKINEVAVAGGVSANNGLRNSFREHAGKYGWNIYIPKFSFTTDNAAMIAITGYYK
YLDNDFCTIDKPAYSRVTI
>Mature_339_residues
MDTIILGIESSCDDTSAAVIKNGVLLSNVVSSQAVHEAYGGVVPELASRAHQQNIVPVVHEALKRAGVTKEQLSAVAFTR
GPGLMGSLLVGVSFAKGFARSLNIPMIDVNHLQAHVLAHFIKESEEDNNQPKFPFLCLLVSGGNSQIILVKAYNDMEVLG
QTIDDAAGEAIDKCSKVMGLGYPGGPIIDKLARQGNPKAFTFSKPHIPDYNYSFSGLKTSFLYSLRDWLKEDPDFIEHHK
NDLAASLEATIVDILMDKLRKAAKNLKINEVAVAGGVSANNGLRNSFREHAGKYGWNIYIPKFSFTTDNAAMIAITGYYK
YLDNDFCTIDKPAYSRVTI

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=342, Percent_Identity=33.9181286549708, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI8923380, Length=326, Percent_Identity=27.3006134969325, Blast_Score=112, Evalue=3e-25,
Organism=Escherichia coli, GI1789445, Length=321, Percent_Identity=42.0560747663551, Blast_Score=261, Evalue=5e-71,
Organism=Caenorhabditis elegans, GI17557464, Length=330, Percent_Identity=29.6969696969697, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI71995670, Length=326, Percent_Identity=30.0613496932515, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6320099, Length=365, Percent_Identity=30.6849315068493, Blast_Score=146, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6322891, Length=352, Percent_Identity=24.1477272727273, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI20129063, Length=359, Percent_Identity=32.033426183844, Blast_Score=177, Evalue=7e-45,
Organism=Drosophila melanogaster, GI21357207, Length=326, Percent_Identity=28.5276073619632, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_BACV8 (A6L5E2)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001300528.1
- ProteinModelPortal:   A6L5E2
- SMR:   A6L5E2
- STRING:   A6L5E2
- MEROPS:   M22.001
- GeneID:   5304238
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_3277
- NMPDR:   fig|435590.6.peg.3056
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   MEVIGQT
- ProtClustDB:   PRK09604
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36940; Mature: 36940

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTIILGIESSCDDTSAAVIKNGVLLSNVVSSQAVHEAYGGVVPELASRAHQQNIVPVVH
CCEEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHH
EALKRAGVTKEQLSAVAFTRGPGLMGSLLVGVSFAKGFARSLNIPMIDVNHLQAHVLAHF
HHHHHCCCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
IKESEEDNNQPKFPFLCLLVSGGNSQIILVKAYNDMEVLGQTIDDAAGEAIDKCSKVMGL
HHHCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
GYPGGPIIDKLARQGNPKAFTFSKPHIPDYNYSFSGLKTSFLYSLRDWLKEDPDFIEHHK
CCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
NDLAASLEATIVDILMDKLRKAAKNLKINEVAVAGGVSANNGLRNSFREHAGKYGWNIYI
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEE
PKFSFTTDNAAMIAITGYYKYLDNDFCTIDKPAYSRVTI
EEEEECCCCCEEEEEEHHHHHHCCCCEEECCCCCCCCCC
>Mature Secondary Structure
MDTIILGIESSCDDTSAAVIKNGVLLSNVVSSQAVHEAYGGVVPELASRAHQQNIVPVVH
CCEEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHH
EALKRAGVTKEQLSAVAFTRGPGLMGSLLVGVSFAKGFARSLNIPMIDVNHLQAHVLAHF
HHHHHCCCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
IKESEEDNNQPKFPFLCLLVSGGNSQIILVKAYNDMEVLGQTIDDAAGEAIDKCSKVMGL
HHHCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
GYPGGPIIDKLARQGNPKAFTFSKPHIPDYNYSFSGLKTSFLYSLRDWLKEDPDFIEHHK
CCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
NDLAASLEATIVDILMDKLRKAAKNLKINEVAVAGGVSANNGLRNSFREHAGKYGWNIYI
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEE
PKFSFTTDNAAMIAITGYYKYLDNDFCTIDKPAYSRVTI
EEEEECCCCCEEEEEEHHHHHHCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA