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The map label for this gene is map [C]

Identifier: 150005783

GI number: 150005783

Start: 4108318

End: 4109172

Strand: Direct

Name: map [C]

Synonym: BVU_3276

Alternate gene names: 150005783

Gene position: 4108318-4109172 (Clockwise)

Preceding gene: 150005781

Following gene: 150005784

Centisome position: 79.57

GC content: 41.52

Gene sequence:

>855_bases
ATGAAAAGAAATAAAATAAACTGGAGAGTTCCCAAAGGTATGGAACTCACAGAGTTAGATAAAAAGGTTCTCTATTATCA
AGATAGAGGTCATTTAGTACCTTCACGTGAACTGATCAAGACACCGGAACAGATTGAAGGAATACGCCGTAGCGGTATTG
TCAATACCGGAGTGCTAGACCTTGTAGAACATGAGATCCATGCAGGCATGAGCACATTGGAAATAGACAAGCTGGTTTAT
GAATATACGAAAGATCACGGTGGCATTCCTGCAACCTTAGGTTATGACGGTTTTCCCAAAAGTTGCTGCACCTCTATCAA
TGAGGTTGTTTGTCACGGTATTCCCAATGAATTCGATATTCTGGAAGAAGGAGATATCATCAATGTGGATTGTACTACCA
TTCTTGATGGTTATTATGCCGATGCATCGCGTATGTTTACCATTGGAAAAACCACACCTCAAAAAGAAAAACTGGTACGA
GTAGCTAAAGAATGTCTGGAGATAGGCATGGAAGCTGCGAAACCATTTGGTTTTGTAGGGGACATAGGACATGCAATTGA
AAAACATGCTAAAAAAAATGGATTCTCAGTAGTGCGTGATCTCTGCGGACACGGAGTAGGCATAGAGTTCCATGAAGAAC
CGGATGTAGAACATTTCGGGAAAAAAGGAACTGGTATGCTATTGGTGCCGGGAATGGTTTTTACCATTGAACCAATGATC
AATATGGGAACATGGGAAGTCTTCATTGATGAGGAAGATGGCTGGACTGTAGTCACCGAAGACGAACAGCCGTCTGCACA
GTGGGAACATACTTTCGTTATGACAGATAACGGACTTGAAATTCTGACACATTAA

Upstream 100 bases:

>100_bases
AAATTTCATGTAAATTCTCTTTTTATGAAGATATTTATTGCCGGATGAGCCATTTTTACAAATATTTCCTCTAACTTTGT
AAGTCAATTAATCCTTTGAT

Downstream 100 bases:

>100_bases
TATATATAATAAGGTATAGAAATATGGATACAATTATATTAGGTATAGAATCTTCCTGTGACGACACATCAGCCGCAGTT
ATCAAGAATGGCGTATTGTT

Product: putative methionine aminopeptidase A

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MKRNKINWRVPKGMELTELDKKVLYYQDRGHLVPSRELIKTPEQIEGIRRSGIVNTGVLDLVEHEIHAGMSTLEIDKLVY
EYTKDHGGIPATLGYDGFPKSCCTSINEVVCHGIPNEFDILEEGDIINVDCTTILDGYYADASRMFTIGKTTPQKEKLVR
VAKECLEIGMEAAKPFGFVGDIGHAIEKHAKKNGFSVVRDLCGHGVGIEFHEEPDVEHFGKKGTGMLLVPGMVFTIEPMI
NMGTWEVFIDEEDGWTVVTEDEQPSAQWEHTFVMTDNGLEILTH

Sequences:

>Translated_284_residues
MKRNKINWRVPKGMELTELDKKVLYYQDRGHLVPSRELIKTPEQIEGIRRSGIVNTGVLDLVEHEIHAGMSTLEIDKLVY
EYTKDHGGIPATLGYDGFPKSCCTSINEVVCHGIPNEFDILEEGDIINVDCTTILDGYYADASRMFTIGKTTPQKEKLVR
VAKECLEIGMEAAKPFGFVGDIGHAIEKHAKKNGFSVVRDLCGHGVGIEFHEEPDVEHFGKKGTGMLLVPGMVFTIEPMI
NMGTWEVFIDEEDGWTVVTEDEQPSAQWEHTFVMTDNGLEILTH
>Mature_284_residues
MKRNKINWRVPKGMELTELDKKVLYYQDRGHLVPSRELIKTPEQIEGIRRSGIVNTGVLDLVEHEIHAGMSTLEIDKLVY
EYTKDHGGIPATLGYDGFPKSCCTSINEVVCHGIPNEFDILEEGDIINVDCTTILDGYYADASRMFTIGKTTPQKEKLVR
VAKECLEIGMEAAKPFGFVGDIGHAIEKHAKKNGFSVVRDLCGHGVGIEFHEEPDVEHFGKKGTGMLLVPGMVFTIEPMI
NMGTWEVFIDEEDGWTVVTEDEQPSAQWEHTFVMTDNGLEILTH

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=245, Percent_Identity=45.7142857142857, Blast_Score=205, Evalue=4e-53,
Organism=Homo sapiens, GI40385867, Length=245, Percent_Identity=40.8163265306122, Blast_Score=182, Evalue=3e-46,
Organism=Escherichia coli, GI1786364, Length=246, Percent_Identity=49.1869918699187, Blast_Score=245, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI71996291, Length=278, Percent_Identity=41.0071942446043, Blast_Score=194, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6323273, Length=259, Percent_Identity=42.4710424710425, Blast_Score=211, Evalue=1e-55,
Organism=Drosophila melanogaster, GI21355531, Length=246, Percent_Identity=41.0569105691057, Blast_Score=191, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24583427, Length=269, Percent_Identity=36.0594795539033, Blast_Score=172, Evalue=3e-43,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 31837; Mature: 31837

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRNKINWRVPKGMELTELDKKVLYYQDRGHLVPSRELIKTPEQIEGIRRSGIVNTGVLD
CCCCCCEEECCCCCCHHHHHCEEEEECCCCCCCCCHHHHCCHHHHHHHHHCCCCCCHHHH
LVEHEIHAGMSTLEIDKLVYEYTKDHGGIPATLGYDGFPKSCCTSINEVVCHGIPNEFDI
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCCE
LEEGDIINVDCTTILDGYYADASRMFTIGKTTPQKEKLVRVAKECLEIGMEAAKPFGFVG
ECCCCEEEEEHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
DIGHAIEKHAKKNGFSVVRDLCGHGVGIEFHEEPDVEHFGKKGTGMLLVPGMVFTIEPMI
HHHHHHHHHHHCCHHHHHHHHHCCCCCEEECCCCCHHHHCCCCCCEEEECCEEEEEECCC
NMGTWEVFIDEEDGWTVVTEDEQPSAQWEHTFVMTDNGLEILTH
CCCEEEEEEECCCCEEEEECCCCCCCCEEEEEEEECCCEEEECC
>Mature Secondary Structure
MKRNKINWRVPKGMELTELDKKVLYYQDRGHLVPSRELIKTPEQIEGIRRSGIVNTGVLD
CCCCCCEEECCCCCCHHHHHCEEEEECCCCCCCCCHHHHCCHHHHHHHHHCCCCCCHHHH
LVEHEIHAGMSTLEIDKLVYEYTKDHGGIPATLGYDGFPKSCCTSINEVVCHGIPNEFDI
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCCE
LEEGDIINVDCTTILDGYYADASRMFTIGKTTPQKEKLVRVAKECLEIGMEAAKPFGFVG
ECCCCEEEEEHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
DIGHAIEKHAKKNGFSVVRDLCGHGVGIEFHEEPDVEHFGKKGTGMLLVPGMVFTIEPMI
HHHHHHHHHHHCCHHHHHHHHHCCCCCEEECCCCCHHHHCCCCCCEEEECCEEEEEECCC
NMGTWEVFIDEEDGWTVVTEDEQPSAQWEHTFVMTDNGLEILTH
CCCEEEEEEECCCCEEEEECCCCCCCCEEEEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]