Click here to switch to the map view.

The map label for this gene is nhaC [H]

Identifier: 150005734

GI number: 150005734

Start: 4054306

End: 4055757

Strand: Direct

Name: nhaC [H]

Synonym: BVU_3227

Alternate gene names: 150005734

Gene position: 4054306-4055757 (Clockwise)

Preceding gene: 150005728

Following gene: 150005735

Centisome position: 78.52

GC content: 45.73

Gene sequence:

>1452_bases
ATGAAAGATAACAAAATCCCTTCACCGTTAGTATCCCTTTTACCCGTATTCGTACTTATTTTATTATTGTTTGTCACTAT
CCGTACATTTGGAAGTGATGCCTTGTCCGGTGGCAGCCAAGTCTGTCTGCTAGTGGCTACAGCTGTTTGTGTGCTGATAG
GTATGGCGGGATTCCGTCGTCCGTGGAAGGACTTCGAACTGGCTGTCACCAATAATATAGCCGGGGTAAGTACCGCACTT
ATTATCTTGCTGATCATCGGAGCTTTGTCCGGAGCATGGATGGTCAGCGGTGTAGTCCCTACATTAATATATTATGGCAT
ACAGGTTATTCATCCTCATTTTTTCCTGGTATCCACTTGCATTATTTGTGCGGTAGTATCTGTCATGACAGGCAGCTCAT
GGACTACCATCGCCACTATCGGCATCGCACTGATGGGAATAGGGAAGGCGCAAGGTTTCAGTGAAGGTTGGATTGCAGGT
GCGATTATCTCCGGAGCCTATTTCGGTGATAAAGTTTCTCCGCTTTCGGATACCACCATTCTGGCATCGTCCGTAACGGA
TACACCGCTGTTCACTCACATCCGTTACTTGATGATTACCACCGTTCCATCACTTGTCATCACTTTGATAATCTTTACCA
TAGCCGGATTGTCACATGAAGCCACTGATACCGGTCATATCGCCGAATACACCCGTATATTGAGTGATAAGTTCCATATT
TCATGGTGGTTGATGATTGTCCCCGTTGTCACAGCGATACTGATTGCACGTAAAGTGCCTTCCATCATCACTCTATTTGT
TTCTACGGCTCTGGCTACCGTCTTTGCCTTGATTTTCCAGCCCGGACTATTATGCGAAATCGCCGGACAAGGAGTCGAAG
GGATTGCCGCCTTGTTCAAAGGAGGAATGGGAATGCTTTATGGTGGAACCCAATTGGAAACCGGTAATGCGGAAATAAAC
GAACTGATATCCACTCGCGGAATGGCGGGTATGATGAATACCATCTGGCTGATTATCTGCGCCATGTGTTTCGGAGGGGC
GATGACAGCCGGAGGAATGCTCGGCAGTATCACTTCTGTCTTTGTACGTTTTACGAAAAAGCGGGTAGGAATGGTGTCAT
CCACAGTTGCATCGGGCTTGTTCCTGAATCTTGCTACAGCAGATCAATATATATCCATTATCCTGACGGGTAATATGTTT
AAAGACATCTATAGTGCAAACGGTTATGAAAGCAAACTGCTGAGCCGCACGACGGAAGATTCTGTTACAGTCACTTCGCC
ATTGATACCCTGGAATACATGCGGTATGACACAGGCTACTATCCTTAGTGTTCCCACCATTGTGTATCTGCCTTACGCAT
TCTTTAACATTATCAGTCCCTTGATGAGTATCACAATTGCTATACTGGGATATAAGATAAAGAAAAAAGCAGAACAGCCG
GGCCTGTCATAA

Upstream 100 bases:

>100_bases
GATTGACTTTTAGAACTCAAAAAATATTCCGAACTTTGCACGCTGAAAACCAAATTGATAGTTCTATTTACATTTTGAAT
AAAAATTGAATAAAAAAAGA

Downstream 100 bases:

>100_bases
TAATGATAGGATCTGATGATTATATATCTTTCACGTGAAAGATTAGCAGGGTTCAAAAATAACTTGTACATTTACCCACC
CTAATAAATCATTTTATATT

Product: Na+/H+ antiporter

Products: NA

Alternate protein names: Sodium/hydrogen antiporter; Sodium/proton antiporter [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MKDNKIPSPLVSLLPVFVLILLLFVTIRTFGSDALSGGSQVCLLVATAVCVLIGMAGFRRPWKDFELAVTNNIAGVSTAL
IILLIIGALSGAWMVSGVVPTLIYYGIQVIHPHFFLVSTCIICAVVSVMTGSSWTTIATIGIALMGIGKAQGFSEGWIAG
AIISGAYFGDKVSPLSDTTILASSVTDTPLFTHIRYLMITTVPSLVITLIIFTIAGLSHEATDTGHIAEYTRILSDKFHI
SWWLMIVPVVTAILIARKVPSIITLFVSTALATVFALIFQPGLLCEIAGQGVEGIAALFKGGMGMLYGGTQLETGNAEIN
ELISTRGMAGMMNTIWLIICAMCFGGAMTAGGMLGSITSVFVRFTKKRVGMVSSTVASGLFLNLATADQYISIILTGNMF
KDIYSANGYESKLLSRTTEDSVTVTSPLIPWNTCGMTQATILSVPTIVYLPYAFFNIISPLMSITIAILGYKIKKKAEQP
GLS

Sequences:

>Translated_483_residues
MKDNKIPSPLVSLLPVFVLILLLFVTIRTFGSDALSGGSQVCLLVATAVCVLIGMAGFRRPWKDFELAVTNNIAGVSTAL
IILLIIGALSGAWMVSGVVPTLIYYGIQVIHPHFFLVSTCIICAVVSVMTGSSWTTIATIGIALMGIGKAQGFSEGWIAG
AIISGAYFGDKVSPLSDTTILASSVTDTPLFTHIRYLMITTVPSLVITLIIFTIAGLSHEATDTGHIAEYTRILSDKFHI
SWWLMIVPVVTAILIARKVPSIITLFVSTALATVFALIFQPGLLCEIAGQGVEGIAALFKGGMGMLYGGTQLETGNAEIN
ELISTRGMAGMMNTIWLIICAMCFGGAMTAGGMLGSITSVFVRFTKKRVGMVSSTVASGLFLNLATADQYISIILTGNMF
KDIYSANGYESKLLSRTTEDSVTVTSPLIPWNTCGMTQATILSVPTIVYLPYAFFNIISPLMSITIAILGYKIKKKAEQP
GLS
>Mature_483_residues
MKDNKIPSPLVSLLPVFVLILLLFVTIRTFGSDALSGGSQVCLLVATAVCVLIGMAGFRRPWKDFELAVTNNIAGVSTAL
IILLIIGALSGAWMVSGVVPTLIYYGIQVIHPHFFLVSTCIICAVVSVMTGSSWTTIATIGIALMGIGKAQGFSEGWIAG
AIISGAYFGDKVSPLSDTTILASSVTDTPLFTHIRYLMITTVPSLVITLIIFTIAGLSHEATDTGHIAEYTRILSDKFHI
SWWLMIVPVVTAILIARKVPSIITLFVSTALATVFALIFQPGLLCEIAGQGVEGIAALFKGGMGMLYGGTQLETGNAEIN
ELISTRGMAGMMNTIWLIICAMCFGGAMTAGGMLGSITSVFVRFTKKRVGMVSSTVASGLFLNLATADQYISIILTGNMF
KDIYSANGYESKLLSRTTEDSVTVTSPLIPWNTCGMTQATILSVPTIVYLPYAFFNIISPLMSITIAILGYKIKKKAEQP
GLS

Specific function: Na(+)/H(+) antiporter. Involved in pH homeostasis and sodium extrusion [H]

COG id: COG1757

COG function: function code C; Na+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaC Na(+)/H(+) antiporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004770
- InterPro:   IPR018461 [H]

Pfam domain/function: PF03553 Na_H_antiporter [H]

EC number: NA

Molecular weight: Translated: 51407; Mature: 51407

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDNKIPSPLVSLLPVFVLILLLFVTIRTFGSDALSGGSQVCLLVATAVCVLIGMAGFRR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHCCC
PWKDFELAVTNNIAGVSTALIILLIIGALSGAWMVSGVVPTLIYYGIQVIHPHFFLVSTC
CCCCCEEEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IICAVVSVMTGSSWTTIATIGIALMGIGKAQGFSEGWIAGAIISGAYFGDKVSPLSDTTI
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHH
LASSVTDTPLFTHIRYLMITTVPSLVITLIIFTIAGLSHEATDTGHIAEYTRILSDKFHI
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHH
SWWLMIVPVVTAILIARKVPSIITLFVSTALATVFALIFQPGLLCEIAGQGVEGIAALFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHCCCHHHHHHHHH
GGMGMLYGGTQLETGNAEINELISTRGMAGMMNTIWLIICAMCFGGAMTAGGMLGSITSV
CCCCEEECCCEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHH
FVRFTKKRVGMVSSTVASGLFLNLATADQYISIILTGNMFKDIYSANGYESKLLSRTTED
HHHHHHHHHHHHHHHHHHHHHEEEEHHHHEEEEEEECHHHHHHHCCCCHHHHHHHCCCCC
SVTVTSPLIPWNTCGMTQATILSVPTIVYLPYAFFNIISPLMSITIAILGYKIKKKAEQP
CEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLS
CCC
>Mature Secondary Structure
MKDNKIPSPLVSLLPVFVLILLLFVTIRTFGSDALSGGSQVCLLVATAVCVLIGMAGFRR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHCCC
PWKDFELAVTNNIAGVSTALIILLIIGALSGAWMVSGVVPTLIYYGIQVIHPHFFLVSTC
CCCCCEEEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IICAVVSVMTGSSWTTIATIGIALMGIGKAQGFSEGWIAGAIISGAYFGDKVSPLSDTTI
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHH
LASSVTDTPLFTHIRYLMITTVPSLVITLIIFTIAGLSHEATDTGHIAEYTRILSDKFHI
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHH
SWWLMIVPVVTAILIARKVPSIITLFVSTALATVFALIFQPGLLCEIAGQGVEGIAALFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHCCCHHHHHHHHH
GGMGMLYGGTQLETGNAEINELISTRGMAGMMNTIWLIICAMCFGGAMTAGGMLGSITSV
CCCCEEECCCEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHH
FVRFTKKRVGMVSSTVASGLFLNLATADQYISIILTGNMFKDIYSANGYESKLLSRTTED
HHHHHHHHHHHHHHHHHHHHHEEEEHHHHEEEEEEECHHHHHHHCCCCHHHHHHHCCCCC
SVTVTSPLIPWNTCGMTQATILSVPTIVYLPYAFFNIISPLMSITIAILGYKIKKKAEQP
CEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1660475; 9190799 [H]