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The map label for this gene is pepC [H]

Identifier: 150005735

GI number: 150005735

Start: 4055869

End: 4057245

Strand: Direct

Name: pepC [H]

Synonym: BVU_3228

Alternate gene names: 150005735

Gene position: 4055869-4057245 (Clockwise)

Preceding gene: 150005734

Following gene: 150005736

Centisome position: 78.55

GC content: 44.44

Gene sequence:

>1377_bases
ATGAAGAAACACATCACATTCGCCCTTCTGTTTGCGGCTGCATTGACAGCCCAGGCACAACAGGGAGGCATTTCAGGTGA
AATGCTGAATCAAATCAAACAAAGTTATAAGGCAACCCCTGCCGACAAAGCCATCCGTAACGCCTTAGGCGGAACAAGTA
TCAACACGTTGGCATTGAACCAGGAGAACCGTGCCGATTTTGATACGGAGTTTTCACACAAGGTGCTATCCAAGGGAATA
ACCGACCAACAATCTTCCGGTCGTTGCTGGCTTTTTACCGGACTGAACGTGCTCCGCAGCCAGATGATTGCCAAATACGG
ACTGGATGAGATGGAGTTCTCACAGAACTACTGCTTTTTCTACGACCAATTAGAAAAAGCAAACTTATTCTTACAGGGAA
TCATTGATACCAGTGGAAAGCCCATGGACGATAAAATGGTGGAATGGCTGTTCAAGCATCCCTTAAGCGATGGAGGACAA
TTCACAGGAGTATCGGATATTATAGAGAAATACGGACTGGTCCCCAAGAGTGCAATGGTGGAAACTTTCAGCAGTGAGAA
TACCGGAAAGATGAGTAGTCTGATAGGACTGAAACTGAAGGAATTTGGTTTACAACTACGCGAAGCCGCCGCTACCGGAG
CGAAGCCGGCCGAACTGGAAAAGAAAAAGACAAAAATGCTGGGAACGGTTTATCGTATGCTGGTGCTGACCCTTGGCGAA
CCTGTTTCCACCTTTACATGGAGTCTGAAGGGTGGGGAAGCGAAAGAATATACTCCGGTGTCTTTCTATAAAGAGTTTTT
GGGAAATGATTTGACCAATAACTATGTAATGCTGATGAATGATCCCAGCCGCGAGTTTTATAAATGTTATGAAATAGATT
TTGACCGTCACCGTTATGATGGCAAGAATTGGACTTATGTAAACTTGCCGATAGAGGATATTAAAGAAATAGCCATAGCT
TCCATCAAGGACAGTACCATGATGTATTTTTCTTGTGATGTAGGCAAGTTCCTTGATAGTAAACGTGGCTTGCTGGACCC
TGATAATTATGATTACGAATCATTGATGGGAACTACTTTCGGTATGGACAAGAAACAACGTATCCAAACTTTCTCCAGTG
GCAGCAGTCATGCCATGACCTTGATGGCGGTGGACTTGGATAAAGCGGGAAAGCCGAAAAAATGGATGGTGGAAAACAGT
TGGGGCAGTGCCAGTGGATACAGAGGACACCTTATCATGACAGATAAATGGTTTGATGAATATATGTTCCGTGTGGTGGC
AGAAAAGAAATATGTTCCTGCCAAGGTGCTGGATATTTTAAAACAGAAACCAATCCGTCTTCCGGCATGGGACCCGATGT
TTGCTGACGAAGAATAA

Upstream 100 bases:

>100_bases
TCTGATGATTATATATCTTTCACGTGAAAGATTAGCAGGGTTCAAAAATAACTTGTACATTTACCCACCCTAATAAATCA
TTTTATATTTTTACAATAAT

Downstream 100 bases:

>100_bases
GCGTTATCTCTCTACATTGTATATAATTTAAGCGGACTGTACAGAAAAGAAAGACTGTACAGTCCGTTTTTTTATTCTAA
GGCATTGTGTATGTCTGTCA

Product: putative aminopeptidase C

Products: NA

Alternate protein names: Bleomycin hydrolase [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKKHITFALLFAAALTAQAQQGGISGEMLNQIKQSYKATPADKAIRNALGGTSINTLALNQENRADFDTEFSHKVLSKGI
TDQQSSGRCWLFTGLNVLRSQMIAKYGLDEMEFSQNYCFFYDQLEKANLFLQGIIDTSGKPMDDKMVEWLFKHPLSDGGQ
FTGVSDIIEKYGLVPKSAMVETFSSENTGKMSSLIGLKLKEFGLQLREAAATGAKPAELEKKKTKMLGTVYRMLVLTLGE
PVSTFTWSLKGGEAKEYTPVSFYKEFLGNDLTNNYVMLMNDPSREFYKCYEIDFDRHRYDGKNWTYVNLPIEDIKEIAIA
SIKDSTMMYFSCDVGKFLDSKRGLLDPDNYDYESLMGTTFGMDKKQRIQTFSSGSSHAMTLMAVDLDKAGKPKKWMVENS
WGSASGYRGHLIMTDKWFDEYMFRVVAEKKYVPAKVLDILKQKPIRLPAWDPMFADEE

Sequences:

>Translated_458_residues
MKKHITFALLFAAALTAQAQQGGISGEMLNQIKQSYKATPADKAIRNALGGTSINTLALNQENRADFDTEFSHKVLSKGI
TDQQSSGRCWLFTGLNVLRSQMIAKYGLDEMEFSQNYCFFYDQLEKANLFLQGIIDTSGKPMDDKMVEWLFKHPLSDGGQ
FTGVSDIIEKYGLVPKSAMVETFSSENTGKMSSLIGLKLKEFGLQLREAAATGAKPAELEKKKTKMLGTVYRMLVLTLGE
PVSTFTWSLKGGEAKEYTPVSFYKEFLGNDLTNNYVMLMNDPSREFYKCYEIDFDRHRYDGKNWTYVNLPIEDIKEIAIA
SIKDSTMMYFSCDVGKFLDSKRGLLDPDNYDYESLMGTTFGMDKKQRIQTFSSGSSHAMTLMAVDLDKAGKPKKWMVENS
WGSASGYRGHLIMTDKWFDEYMFRVVAEKKYVPAKVLDILKQKPIRLPAWDPMFADEE
>Mature_458_residues
MKKHITFALLFAAALTAQAQQGGISGEMLNQIKQSYKATPADKAIRNALGGTSINTLALNQENRADFDTEFSHKVLSKGI
TDQQSSGRCWLFTGLNVLRSQMIAKYGLDEMEFSQNYCFFYDQLEKANLFLQGIIDTSGKPMDDKMVEWLFKHPLSDGGQ
FTGVSDIIEKYGLVPKSAMVETFSSENTGKMSSLIGLKLKEFGLQLREAAATGAKPAELEKKKTKMLGTVYRMLVLTLGE
PVSTFTWSLKGGEAKEYTPVSFYKEFLGNDLTNNYVMLMNDPSREFYKCYEIDFDRHRYDGKNWTYVNLPIEDIKEIAIA
SIKDSTMMYFSCDVGKFLDSKRGLLDPDNYDYESLMGTTFGMDKKQRIQTFSSGSSHAMTLMAVDLDKAGKPKKWMVENS
WGSASGYRGHLIMTDKWFDEYMFRVVAEKKYVPAKVLDILKQKPIRLPAWDPMFADEE

Specific function: Unknown

COG id: COG3579

COG function: function code E; Aminopeptidase C

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C1 family [H]

Homologues:

Organism=Homo sapiens, GI4557367, Length=451, Percent_Identity=36.8070953436807, Blast_Score=315, Evalue=8e-86,
Organism=Saccharomyces cerevisiae, GI6324090, Length=449, Percent_Identity=31.6258351893096, Blast_Score=225, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24640588, Length=451, Percent_Identity=33.0376940133038, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI161077632, Length=451, Percent_Identity=33.0376940133038, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI161077630, Length=362, Percent_Identity=34.8066298342541, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI20130175, Length=409, Percent_Identity=26.161369193154, Blast_Score=150, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000169
- InterPro:   IPR004134 [H]

Pfam domain/function: PF03051 Peptidase_C1_2 [H]

EC number: =3.4.22.40 [H]

Molecular weight: Translated: 51851; Mature: 51851

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00626 RCC1_2 ; PS00139 THIOL_PROTEASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKHITFALLFAAALTAQAQQGGISGEMLNQIKQSYKATPADKAIRNALGGTSINTLALN
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEC
QENRADFDTEFSHKVLSKGITDQQSSGRCWLFTGLNVLRSQMIAKYGLDEMEFSQNYCFF
CCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHCCCEEEE
YDQLEKANLFLQGIIDTSGKPMDDKMVEWLFKHPLSDGGQFTGVSDIIEKYGLVPKSAMV
EHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHH
ETFSSENTGKMSSLIGLKLKEFGLQLREAAATGAKPAELEKKKTKMLGTVYRMLVLTLGE
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PVSTFTWSLKGGEAKEYTPVSFYKEFLGNDLTNNYVMLMNDPSREFYKCYEIDFDRHRYD
CCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHEEHCCCCHHHCCC
GKNWTYVNLPIEDIKEIAIASIKDSTMMYFSCDVGKFLDSKRGLLDPDNYDYESLMGTTF
CCCEEEEECCHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCCCCCCCHHHHHHHHC
GMDKKQRIQTFSSGSSHAMTLMAVDLDKAGKPKKWMVENSWGSASGYRGHLIMTDKWFDE
CCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCEEEEEHHHHHH
YMFRVVAEKKYVPAKVLDILKQKPIRLPAWDPMFADEE
HHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKHITFALLFAAALTAQAQQGGISGEMLNQIKQSYKATPADKAIRNALGGTSINTLALN
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEC
QENRADFDTEFSHKVLSKGITDQQSSGRCWLFTGLNVLRSQMIAKYGLDEMEFSQNYCFF
CCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHCCCEEEE
YDQLEKANLFLQGIIDTSGKPMDDKMVEWLFKHPLSDGGQFTGVSDIIEKYGLVPKSAMV
EHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHH
ETFSSENTGKMSSLIGLKLKEFGLQLREAAATGAKPAELEKKKTKMLGTVYRMLVLTLGE
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PVSTFTWSLKGGEAKEYTPVSFYKEFLGNDLTNNYVMLMNDPSREFYKCYEIDFDRHRYD
CCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHEEHCCCCHHHCCC
GKNWTYVNLPIEDIKEIAIASIKDSTMMYFSCDVGKFLDSKRGLLDPDNYDYESLMGTTF
CCCEEEEECCHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCCCCCCCHHHHHHHHC
GMDKKQRIQTFSSGSSHAMTLMAVDLDKAGKPKKWMVENSWGSASGYRGHLIMTDKWFDE
CCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCEEEEEHHHHHH
YMFRVVAEKKYVPAKVLDILKQKPIRLPAWDPMFADEE
HHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7851736 [H]