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The map label for this gene is hisC [H]

Identifier: 150005628

GI number: 150005628

Start: 3941204

End: 3942214

Strand: Direct

Name: hisC [H]

Synonym: BVU_3116

Alternate gene names: 150005628

Gene position: 3941204-3942214 (Clockwise)

Preceding gene: 150005627

Following gene: 150005629

Centisome position: 76.33

GC content: 40.75

Gene sequence:

>1011_bases
ATGATTGAAGGACATGGTGATGATGCTTATAAGTATAAAGCAATAAAGATAAATTTCAGTTCAAACGTATATAATCATGT
AGACCATAGCGGATTACATCAACATTTGTTTCAGCAGATGGAAAGTATCCGTACGTACCCCGAACCGGAACCTTATTCGT
TGGAAAAGGTTTTAGCGGAACGGTTTCATCTTTCGTCTGAAGAGGTTTGTGTGACCAATGGGGCTACGGAAGCCATTTAT
TTAATAGCTCAGACATTCAGGAATCAGATTTCGGCTATCTTGATGCCCACTTTCAGCGAATATGCGGATGCTTGTCGTCT
GCATGGTCATAAAGTGGTTCCTATATATAATTTGAACCGTTTGCCGGATAGGGGGAGGTTGATATGGTTATGTAATCCTA
ATAATCCCACAGGAGAGCTTAGGGAGAAGGAAGTCTTGACAGCCTGTATAAAACAAAATCCGCAGCGTATTTTTATCATG
GACCAGTCGTATGAATTCTTTACACAGAAGGCTTTGCTTACAGCCAAGGAGGCTGCGGAATTTCCGAATGTTATTCTGTT
GCATTCCATGACAAAACGTTTTGCCGTGCCCGGCTTGCGTTTAGGATATATCACTGCATGTAAAGAACTGCTACATGAAA
TCCGGACACAGCGGATGCCTTGGTCTGTTAATCAGTTGGCTATAGAGGCCGGGCATTATTTATTGTCTTCTTCTCAATAT
GATATAGATATCTCTTTGTTATTGAGGGAAAAAGAGAGATTAGTTCAATCTTTACTTTCAATAGGGGGAATGGAGATCTG
GCCATCGGATACTCACTATATGTTAGTTCAATTGCGGATGGGAAAGGCGGCGGCTTTGAAAGAATATCTGGCAACAGAGC
AGGGAATTCTTATTCGTGACGCATCCAATTTTGAAGGGCTGAATGAACACTTCTTCCGTATTGCTACACAAACTCCGGAA
GAAAATGACAAACTGGTAGAAAGTATAAAGAAATGGACATATATGTATTAA

Upstream 100 bases:

>100_bases
TTGGATTACCGGACTTATAAAGAAGAACAATATGATAAATTGGCAGAGCATGTACGCAGTCATCTTAATCTGCCTTTGTT
GTACCAAATAATGAGTGGGA

Downstream 100 bases:

>100_bases
TTCTTCCGTTGTTGATAGGATGGATATTAGATAAATTGCTTGGGGATCCGATAGGATTGCCGCATCCAGTGGTAGGATTC
GGGAAGCTGATCTCTTTTTG

Product: putative histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MIEGHGDDAYKYKAIKINFSSNVYNHVDHSGLHQHLFQQMESIRTYPEPEPYSLEKVLAERFHLSSEEVCVTNGATEAIY
LIAQTFRNQISAILMPTFSEYADACRLHGHKVVPIYNLNRLPDRGRLIWLCNPNNPTGELREKEVLTACIKQNPQRIFIM
DQSYEFFTQKALLTAKEAAEFPNVILLHSMTKRFAVPGLRLGYITACKELLHEIRTQRMPWSVNQLAIEAGHYLLSSSQY
DIDISLLLREKERLVQSLLSIGGMEIWPSDTHYMLVQLRMGKAAALKEYLATEQGILIRDASNFEGLNEHFFRIATQTPE
ENDKLVESIKKWTYMY

Sequences:

>Translated_336_residues
MIEGHGDDAYKYKAIKINFSSNVYNHVDHSGLHQHLFQQMESIRTYPEPEPYSLEKVLAERFHLSSEEVCVTNGATEAIY
LIAQTFRNQISAILMPTFSEYADACRLHGHKVVPIYNLNRLPDRGRLIWLCNPNNPTGELREKEVLTACIKQNPQRIFIM
DQSYEFFTQKALLTAKEAAEFPNVILLHSMTKRFAVPGLRLGYITACKELLHEIRTQRMPWSVNQLAIEAGHYLLSSSQY
DIDISLLLREKERLVQSLLSIGGMEIWPSDTHYMLVQLRMGKAAALKEYLATEQGILIRDASNFEGLNEHFFRIATQTPE
ENDKLVESIKKWTYMY
>Mature_336_residues
MIEGHGDDAYKYKAIKINFSSNVYNHVDHSGLHQHLFQQMESIRTYPEPEPYSLEKVLAERFHLSSEEVCVTNGATEAIY
LIAQTFRNQISAILMPTFSEYADACRLHGHKVVPIYNLNRLPDRGRLIWLCNPNNPTGELREKEVLTACIKQNPQRIFIM
DQSYEFFTQKALLTAKEAAEFPNVILLHSMTKRFAVPGLRLGYITACKELLHEIRTQRMPWSVNQLAIEAGHYLLSSSQY
DIDISLLLREKERLVQSLLSIGGMEIWPSDTHYMLVQLRMGKAAALKEYLATEQGILIRDASNFEGLNEHFFRIATQTPE
ENDKLVESIKKWTYMY

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=309, Percent_Identity=25.5663430420712, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322075, Length=300, Percent_Identity=22.3333333333333, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 38760; Mature: 38760

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEGHGDDAYKYKAIKINFSSNVYNHVDHSGLHQHLFQQMESIRTYPEPEPYSLEKVLAE
CCCCCCCCCEEEEEEEEEECCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
RFHLSSEEVCVTNGATEAIYLIAQTFRNQISAILMPTFSEYADACRLHGHKVVPIYNLNR
HHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCC
LPDRGRLIWLCNPNNPTGELREKEVLTACIKQNPQRIFIMDQSYEFFTQKALLTAKEAAE
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHC
FPNVILLHSMTKRFAVPGLRLGYITACKELLHEIRTQRMPWSVNQLAIEAGHYLLSSSQY
CCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
DIDISLLLREKERLVQSLLSIGGMEIWPSDTHYMLVQLRMGKAAALKEYLATEQGILIRD
CEEHHHHHHHHHHHHHHHHHHCCEEECCCCCEEEEEEEECCHHHHHHHHHHCCCCEEEEE
ASNFEGLNEHFFRIATQTPEENDKLVESIKKWTYMY
CCCCCCHHHHHEEEECCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIEGHGDDAYKYKAIKINFSSNVYNHVDHSGLHQHLFQQMESIRTYPEPEPYSLEKVLAE
CCCCCCCCCEEEEEEEEEECCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
RFHLSSEEVCVTNGATEAIYLIAQTFRNQISAILMPTFSEYADACRLHGHKVVPIYNLNR
HHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCC
LPDRGRLIWLCNPNNPTGELREKEVLTACIKQNPQRIFIMDQSYEFFTQKALLTAKEAAE
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHC
FPNVILLHSMTKRFAVPGLRLGYITACKELLHEIRTQRMPWSVNQLAIEAGHYLLSSSQY
CCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
DIDISLLLREKERLVQSLLSIGGMEIWPSDTHYMLVQLRMGKAAALKEYLATEQGILIRD
CEEHHHHHHHHHHHHHHHHHHCCEEECCCCCEEEEEEEECCHHHHHHHHHHCCCCEEEEE
ASNFEGLNEHFFRIATQTPEENDKLVESIKKWTYMY
CCCCCCHHHHHEEEECCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA