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The map label for this gene is cobD [H]

Identifier: 150005629

GI number: 150005629

Start: 3942196

End: 3943128

Strand: Direct

Name: cobD [H]

Synonym: BVU_3117

Alternate gene names: 150005629

Gene position: 3942196-3943128 (Clockwise)

Preceding gene: 150005628

Following gene: 150005630

Centisome position: 76.35

GC content: 41.91

Gene sequence:

>933_bases
ATGGACATATATGTATTAATTCTTCCGTTGTTGATAGGATGGATATTAGATAAATTGCTTGGGGATCCGATAGGATTGCC
GCATCCAGTGGTAGGATTCGGGAAGCTGATCTCTTTTTGTGAGAAACGATGGAACTGTGGGACACATCGGATGTTGAAAG
GAGGGGTGGCGGCCATTATGCTTATTTTGCTAGTGTATGCAGGATCTGTTTTGGTATTGCATTATCTGTTTGTGCTAAAC
CGTTGGTTGGGTATTATTCTCTCTGCTGTGCTTGTTTTCTATTGTTTGGCAGGAACTACACTTATCAACGAAGTAAGGCA
GGTTTTTTTGGCTGCGGATCATTCTTTGGAGGAAGGAAGAAAGCAGGTTTCCCGTATTGTAGGGCGTGATACTTCGGAAC
TGACAGATCAGGAAGTGCGTACGGCTGCTTTGGAAACATTGGCTGAGAATTTGAGTGATGGGGTTATTGCTCCATTATTC
TGGTATTTGCTTTTGGGAGTTCCCGGTATGCTTGCTTATAAGATGGTTAATACGCTTGACTCTATGATAGGCTATAGGAA
TGAACGTTATCTTCAGTTTGGTTGTGTCGCTGCACATATTGATGATATGGCGAACTATATTCCGGCTCGTCTAACTGCAT
TTTTAATGGTGCTGTGTGCAGGGCGTCCCGGTTTGCTGAGATTTGTAGGTAAATATGGTAACCGGCATGCGAGTCCTAAT
TCAGGTTATCCGGAGTCTGCTTTAGCAGGTATCTTGAATTGCCGTTTTGGAGGTCCTCATGTTTATTTTGGAGAGATAGT
CTATAAACCTTTTATTGGAGATAAGGATCGGTTTATCCATACACAGGATATGCATAAAGCTGTCGATATAAACAGGAGAG
CAGAAATCTTGATGGTTATAGTAAATATTGTTTGCTTATATTTGGTCGGTTGA

Upstream 100 bases:

>100_bases
TTCGTGACGCATCCAATTTTGAAGGGCTGAATGAACACTTCTTCCGTATTGCTACACAAACTCCGGAAGAAAATGACAAA
CTGGTAGAAAGTATAAAGAA

Downstream 100 bases:

>100_bases
AAAATATATATTACTTTTGTTTCCGTTTTAGAGATGCGGCAGTAGCTCAGTTGGTAGAGCATCAGCTTCCCAAGCTGAGG
GTCACGAGTTCGAACCTCGC

Product: cobalamin biosynthesis protein CobD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MDIYVLILPLLIGWILDKLLGDPIGLPHPVVGFGKLISFCEKRWNCGTHRMLKGGVAAIMLILLVYAGSVLVLHYLFVLN
RWLGIILSAVLVFYCLAGTTLINEVRQVFLAADHSLEEGRKQVSRIVGRDTSELTDQEVRTAALETLAENLSDGVIAPLF
WYLLLGVPGMLAYKMVNTLDSMIGYRNERYLQFGCVAAHIDDMANYIPARLTAFLMVLCAGRPGLLRFVGKYGNRHASPN
SGYPESALAGILNCRFGGPHVYFGEIVYKPFIGDKDRFIHTQDMHKAVDINRRAEILMVIVNIVCLYLVG

Sequences:

>Translated_310_residues
MDIYVLILPLLIGWILDKLLGDPIGLPHPVVGFGKLISFCEKRWNCGTHRMLKGGVAAIMLILLVYAGSVLVLHYLFVLN
RWLGIILSAVLVFYCLAGTTLINEVRQVFLAADHSLEEGRKQVSRIVGRDTSELTDQEVRTAALETLAENLSDGVIAPLF
WYLLLGVPGMLAYKMVNTLDSMIGYRNERYLQFGCVAAHIDDMANYIPARLTAFLMVLCAGRPGLLRFVGKYGNRHASPN
SGYPESALAGILNCRFGGPHVYFGEIVYKPFIGDKDRFIHTQDMHKAVDINRRAEILMVIVNIVCLYLVG
>Mature_310_residues
MDIYVLILPLLIGWILDKLLGDPIGLPHPVVGFGKLISFCEKRWNCGTHRMLKGGVAAIMLILLVYAGSVLVLHYLFVLN
RWLGIILSAVLVFYCLAGTTLINEVRQVFLAADHSLEEGRKQVSRIVGRDTSELTDQEVRTAALETLAENLSDGVIAPLF
WYLLLGVPGMLAYKMVNTLDSMIGYRNERYLQFGCVAAHIDDMANYIPARLTAFLMVLCAGRPGLLRFVGKYGNRHASPN
SGYPESALAGILNCRFGGPHVYFGEIVYKPFIGDKDRFIHTQDMHKAVDINRRAEILMVIVNIVCLYLVG

Specific function: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group [H]

COG id: COG1270

COG function: function code H; Cobalamin biosynthesis protein CobD/CbiB

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobD/CbiB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004485 [H]

Pfam domain/function: PF03186 CobD_Cbib [H]

EC number: NA

Molecular weight: Translated: 34500; Mature: 34500

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIYVLILPLLIGWILDKLLGDPIGLPHPVVGFGKLISFCEKRWNCGTHRMLKGGVAAIM
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LILLVYAGSVLVLHYLFVLNRWLGIILSAVLVFYCLAGTTLINEVRQVFLAADHSLEEGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
KQVSRIVGRDTSELTDQEVRTAALETLAENLSDGVIAPLFWYLLLGVPGMLAYKMVNTLD
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
SMIGYRNERYLQFGCVAAHIDDMANYIPARLTAFLMVLCAGRPGLLRFVGKYGNRHASPN
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCC
SGYPESALAGILNCRFGGPHVYFGEIVYKPFIGDKDRFIHTQDMHKAVDINRRAEILMVI
CCCCHHHHHHHHHCCCCCCCEEHHHHHHCCCCCCCCCEECHHHHHHHHCCCHHHHHHHHH
VNIVCLYLVG
HHHHHHHHCC
>Mature Secondary Structure
MDIYVLILPLLIGWILDKLLGDPIGLPHPVVGFGKLISFCEKRWNCGTHRMLKGGVAAIM
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LILLVYAGSVLVLHYLFVLNRWLGIILSAVLVFYCLAGTTLINEVRQVFLAADHSLEEGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
KQVSRIVGRDTSELTDQEVRTAALETLAENLSDGVIAPLFWYLLLGVPGMLAYKMVNTLD
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
SMIGYRNERYLQFGCVAAHIDDMANYIPARLTAFLMVLCAGRPGLLRFVGKYGNRHASPN
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCC
SGYPESALAGILNCRFGGPHVYFGEIVYKPFIGDKDRFIHTQDMHKAVDINRRAEILMVI
CCCCHHHHHHHHHCCCCCCCEEHHHHHHCCCCCCCCCEECHHHHHHHHCCCHHHHHHHHH
VNIVCLYLVG
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]