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The map label for this gene is waaA [H]

Identifier: 148652675

GI number: 148652675

Start: 1025338

End: 1026969

Strand: Direct

Name: waaA [H]

Synonym: PsycPRwf_0866

Alternate gene names: 148652675

Gene position: 1025338-1026969 (Clockwise)

Preceding gene: 148652674

Following gene: 148652676

Centisome position: 34.42

GC content: 50.98

Gene sequence:

>1632_bases
ATGCCAGACAAAAATGCCACAACCTCCTCTGAACCACCCTCCGCCTTAAACGCAACTGCTGGCCAAAATGGCCAGGCCTT
ATCGCCGCCTTGGTATTATACTTTAGTGATAAAGCTGTTAAAGCCGCTGTATAGGATAGCGCTGTGGCGTCGGCATAATA
AAGCCAATAAGACAGGTTTGCCTGTGGCTGATTACAAAAGTGAAATTGATGCTCGATATGGCCGCCGCTACCCGCTGCCG
CCGCGTTTGGCCACTGCCACAGAGGTCAGTGAGCGCACTTCGGCCTTTTATAACACTCTGATTTGGTGTCATGCCGTGTC
ACTGGGCGAGACCAATACCATTGCGCCTATGCTCAAGCAGATGCTCAAACAAGGCGCAAGGCTATGGATTACCAATACCA
CACAGACTGGATTTGCCCGCACTGAGGCCTTGTTTGCTGAAGCAATAGCTGCCGGTCAAGTGGTGCACACTTTTGTGCCA
GTAGATGACAAGGCTGTGATCCAAAAGTTTGTGGATAATGCCAAGCCAGATTTGGCCATGTTCGTTGAGACTGAGCTGTG
GGCCAATATTTTAGCGGTTCTTAAGCAATCTAATATACCGTCAGTCTTAGTCAATGCCCGCTTATCCCAAAAATCTTATG
ACAACTATGCCAAACATGCTGCCGTTAGTAAGGGCATGGTCCACAACTTAACTATGATTATCGCGCAAGATGCCGACTCC
GCTAAGCGCTTTCGTTATCTGGGCACTGACGTTGTTAAAATCCGCCGTGCCAACTCCTTAAAATGGTCGACCGGCTCCAT
GCAGCCAAAACCGCTAGATCAACTGCGCAGTGAATTTGCCGCAAATACTCAGGCTCTACAGCGTCCGATTTGGGTAGCCG
GCAGTACGCATGATGGCGAGGAGACTGCCGTGCTTAATGCTCATAAGCAGCTATTGACTCAGCCGCATATGGCGAATGCT
TTACTTATCTTAGTGCCGCGCCATCCTGAGCGCTTTGATGCCGTGGCTGAGCTGATTGAACAGACTGGACTTAACTACCG
CAGGCGCAGTGAGCAGCAACTGATTGATGCCGATACTCAAGTGTATTTGGCTGATACCATGGGGGAGCTAGGTGACTGTT
ATGAGCTGTCTGATGTGGCCTTGGTTGGTGGCTCTTTGGTCAATATCGGTGGTCATAATCCGATTGAAGCGGCCAGTCTG
GCTAAGCCTATCATCATGGGGCCTTATACCCAGTCGTGTCATGAATTGGTGAGTGAGTTGAGCGCAGCTGGCGCCCTAGT
GGTGGTAGACGCCGCTGAAGGCCATGCCCAAAAGCGCAGTAATAAACAATCAGCGACTAAAGGCAGCGATGGGGGGCAAA
CACCGGCGCCGCAATCGACGCTGCTGCAAGCTGTGCTTCAGTGGCTAGCCTATCCTGAGCAAGCACAGCGGGCCGGCCAG
CTAGGCGCGCAGCTGGTGGCCAAAAAAAGCGATGCCATGCAAAAGCAGCTAGCTATGATAGAGAGCTTATTGATTAAAAA
GCAAATTGCCTTATCTGCTAAGCCAGATCCTAAACAAGAGCCGCTGGACCTTGATTACTTTAAAGTACGTACCCGCAGCG
ATAGCAGCGATATGGACAGTGGCGAGCTATGA

Upstream 100 bases:

>100_bases
ATAGCAATCGCTATTTTAAACATTTTAAATGGGGTAAAATAACGCCTATTTTTTCCGCCATTGGTTTTATTTCTTTTTAT
AAGGTGATATTGGGTCGATC

Downstream 100 bases:

>100_bases
ACCTAATTTTATTAGATCAAGCGGAGCCATCTAGCGCTCAGACTGTACTTTGTGATCCGGCTCAAATTCAGCACATACGC
CAAGTGCTACAGCTTGGTGT

Product: 3-deoxy-D-manno-octulosonic-acid transferase domain-containing protein

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MPDKNATTSSEPPSALNATAGQNGQALSPPWYYTLVIKLLKPLYRIALWRRHNKANKTGLPVADYKSEIDARYGRRYPLP
PRLATATEVSERTSAFYNTLIWCHAVSLGETNTIAPMLKQMLKQGARLWITNTTQTGFARTEALFAEAIAAGQVVHTFVP
VDDKAVIQKFVDNAKPDLAMFVETELWANILAVLKQSNIPSVLVNARLSQKSYDNYAKHAAVSKGMVHNLTMIIAQDADS
AKRFRYLGTDVVKIRRANSLKWSTGSMQPKPLDQLRSEFAANTQALQRPIWVAGSTHDGEETAVLNAHKQLLTQPHMANA
LLILVPRHPERFDAVAELIEQTGLNYRRRSEQQLIDADTQVYLADTMGELGDCYELSDVALVGGSLVNIGGHNPIEAASL
AKPIIMGPYTQSCHELVSELSAAGALVVVDAAEGHAQKRSNKQSATKGSDGGQTPAPQSTLLQAVLQWLAYPEQAQRAGQ
LGAQLVAKKSDAMQKQLAMIESLLIKKQIALSAKPDPKQEPLDLDYFKVRTRSDSSDMDSGEL

Sequences:

>Translated_543_residues
MPDKNATTSSEPPSALNATAGQNGQALSPPWYYTLVIKLLKPLYRIALWRRHNKANKTGLPVADYKSEIDARYGRRYPLP
PRLATATEVSERTSAFYNTLIWCHAVSLGETNTIAPMLKQMLKQGARLWITNTTQTGFARTEALFAEAIAAGQVVHTFVP
VDDKAVIQKFVDNAKPDLAMFVETELWANILAVLKQSNIPSVLVNARLSQKSYDNYAKHAAVSKGMVHNLTMIIAQDADS
AKRFRYLGTDVVKIRRANSLKWSTGSMQPKPLDQLRSEFAANTQALQRPIWVAGSTHDGEETAVLNAHKQLLTQPHMANA
LLILVPRHPERFDAVAELIEQTGLNYRRRSEQQLIDADTQVYLADTMGELGDCYELSDVALVGGSLVNIGGHNPIEAASL
AKPIIMGPYTQSCHELVSELSAAGALVVVDAAEGHAQKRSNKQSATKGSDGGQTPAPQSTLLQAVLQWLAYPEQAQRAGQ
LGAQLVAKKSDAMQKQLAMIESLLIKKQIALSAKPDPKQEPLDLDYFKVRTRSDSSDMDSGEL
>Mature_542_residues
PDKNATTSSEPPSALNATAGQNGQALSPPWYYTLVIKLLKPLYRIALWRRHNKANKTGLPVADYKSEIDARYGRRYPLPP
RLATATEVSERTSAFYNTLIWCHAVSLGETNTIAPMLKQMLKQGARLWITNTTQTGFARTEALFAEAIAAGQVVHTFVPV
DDKAVIQKFVDNAKPDLAMFVETELWANILAVLKQSNIPSVLVNARLSQKSYDNYAKHAAVSKGMVHNLTMIIAQDADSA
KRFRYLGTDVVKIRRANSLKWSTGSMQPKPLDQLRSEFAANTQALQRPIWVAGSTHDGEETAVLNAHKQLLTQPHMANAL
LILVPRHPERFDAVAELIEQTGLNYRRRSEQQLIDADTQVYLADTMGELGDCYELSDVALVGGSLVNIGGHNPIEAASLA
KPIIMGPYTQSCHELVSELSAAGALVVVDAAEGHAQKRSNKQSATKGSDGGQTPAPQSTLLQAVLQWLAYPEQAQRAGQL
GAQLVAKKSDAMQKQLAMIESLLIKKQIALSAKPDPKQEPLDLDYFKVRTRSDSSDMDSGEL

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA). Transfers two molecules of KDO to lipid IVA [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=415, Percent_Identity=37.1084337349398, Blast_Score=244, Evalue=8e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR007507 [H]

Pfam domain/function: PF00534 Glycos_transf_1; PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 59515; Mature: 59383

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDKNATTSSEPPSALNATAGQNGQALSPPWYYTLVIKLLKPLYRIALWRRHNKANKTGL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PVADYKSEIDARYGRRYPLPPRLATATEVSERTSAFYNTLIWCHAVSLGETNTIAPMLKQ
CHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHH
MLKQGARLWITNTTQTGFARTEALFAEAIAAGQVVHTFVPVDDKAVIQKFVDNAKPDLAM
HHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCEEE
FVETELWANILAVLKQSNIPSVLVNARLSQKSYDNYAKHAAVSKGMVHNLTMIIAQDADS
EEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEEECCCCH
AKRFRYLGTDVVKIRRANSLKWSTGSMQPKPLDQLRSEFAANTQALQRPIWVAGSTHDGE
HHHHHHHCCHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHCCHHHHHCCEEEECCCCCCC
ETAVLNAHKQLLTQPHMANALLILVPRHPERFDAVAELIEQTGLNYRRRSEQQLIDADTQ
HHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCE
VYLADTMGELGDCYELSDVALVGGSLVNIGGHNPIEAASLAKPIIMGPYTQSCHELVSEL
EEEHHHHHHHCCCHHHHHHHHCCCCEEECCCCCCCCHHHHCCCCEECCCHHHHHHHHHHH
SAAGALVVVDAAEGHAQKRSNKQSATKGSDGGQTPAPQSTLLQAVLQWLAYPEQAQRAGQ
HHCCEEEEEECCCCHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
LGAQLVAKKSDAMQKQLAMIESLLIKKQIALSAKPDPKQEPLDLDYFKVRTRSDSSDMDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCC
GEL
CCC
>Mature Secondary Structure 
PDKNATTSSEPPSALNATAGQNGQALSPPWYYTLVIKLLKPLYRIALWRRHNKANKTGL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PVADYKSEIDARYGRRYPLPPRLATATEVSERTSAFYNTLIWCHAVSLGETNTIAPMLKQ
CHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHH
MLKQGARLWITNTTQTGFARTEALFAEAIAAGQVVHTFVPVDDKAVIQKFVDNAKPDLAM
HHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCEEE
FVETELWANILAVLKQSNIPSVLVNARLSQKSYDNYAKHAAVSKGMVHNLTMIIAQDADS
EEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEEECCCCH
AKRFRYLGTDVVKIRRANSLKWSTGSMQPKPLDQLRSEFAANTQALQRPIWVAGSTHDGE
HHHHHHHCCHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHCCHHHHHCCEEEECCCCCCC
ETAVLNAHKQLLTQPHMANALLILVPRHPERFDAVAELIEQTGLNYRRRSEQQLIDADTQ
HHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCE
VYLADTMGELGDCYELSDVALVGGSLVNIGGHNPIEAASLAKPIIMGPYTQSCHELVSEL
EEEHHHHHHHCCCHHHHHHHHCCCCEEECCCCCCCCHHHHCCCCEECCCHHHHHHHHHHH
SAAGALVVVDAAEGHAQKRSNKQSATKGSDGGQTPAPQSTLLQAVLQWLAYPEQAQRAGQ
HHCCEEEEEECCCCHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
LGAQLVAKKSDAMQKQLAMIESLLIKKQIALSAKPDPKQEPLDLDYFKVRTRSDSSDMDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCC
GEL
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]