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The map label for this gene is sucC

Identifier: 148652081

GI number: 148652081

Start: 319653

End: 320822

Strand: Direct

Name: sucC

Synonym: PsycPRwf_0269

Alternate gene names: 148652081

Gene position: 319653-320822 (Clockwise)

Preceding gene: 148652080

Following gene: 148652082

Centisome position: 10.73

GC content: 44.19

Gene sequence:

>1170_bases
ATGAATTTACATGAGTATCAAGCAAAACTATTGCTAGAGAGCTATGGACTACCTATCCAAAAAGGCATCATTGCTTATAA
CGGTGAAGAAGCGGCTGAAGCCTTTGATAAAACCCCAACTGACGTAGCCGTAATTAAAGCACAGGTTCATGCTGGTGGCC
GTGGTAAAGCAGGCGGTGTTAAGCTTGTTAAAACTCGTGAAGAAGCCAAAGAAGTTGCTGAAAGCTTAATCGGTACTAAC
CTAGTGACTTACCAAACTGATGCAGAAGGCCAGCCTGTAAACTTCGTATTGGTTGCCGAAGACATGTACCCAGTAAAAAC
TGAGTTATATCTTGGTGCCGTTGTTGACCGCGCTACTCGCCGCGTAACCTTCATGGCCTCAACTGAAGGTGGTGTTGAGA
TTGAAAAAGTAGCTGAAGAGACTCCTGAGAAAATCTTTAGTATTACCGTTGATCCTTTAGTCGGTCTATTGCCTTTCCAA
GCGCGTGAAGTAGGTTTCAAATTGGGCCTAGAAGGCAAACAAATCAACCAATTCGTTAAACTAATGACTGGCGCTTACAA
AGCGTTCGTTGAAAACGACTTTGACATGATTGAAATCAACCCACTAGCCGTTCGTGAAAATGGTGAATTGGCTTGTGTTG
ACGGCAAAATCGGCGTGGATTCAAACGCTTTATTCCGTCAGCCAAAAATCGCAGCACTTCATGACCCATCACAAGAGAAC
GAGCGTGAGCTTAAAGCTGCTGAATTTGACCTAAACTATGTGGCTCTAGAAGGTAACATTGGTTGTATGGTTAACGGTGC
CGGTCTTGCTATGGCGACTATGGACATCATCAAGCTATACGGCGGCAAGCCAGCTAACTTCCTAGACGTTGGCGGCGGCG
CAACCAAAGATCGCGTTGTTGAAGCTTTCAAAATCATCTTAGAAGATTCAAGCGTACAAGGCGTTCTAATCAACATCTTC
GGTGGTATCGTACGTTGTGACATGATTGCTGAAGCCATTATCGCGGCAGTTAAAGAAGTTAACGTTACTGTACCTGTTGT
GGTTCGCTTAGAAGGTAACAATGCTGAATTGGGCGCTAAGCTATTAGATGAGTCTGACGTTGAAATCATTTCAGCTCAAG
GCCTATCTGATGCTGCACAAAAAATTGTTGATGCTGTAAAAGCGGCATAA

Upstream 100 bases:

>100_bases
GCAGTAAACGGCCGTGGTATTAGGTCATTTATTTGCCGCTATTGCCAAAACATTTAAATCAGCTTTACCCTGCTAAATAA
AAAAACTAAAGGATAACTTT

Downstream 100 bases:

>100_bases
TTCGCCTATCACAACTGTATCAAACCTATAATAAGTGAATCCTACTAGGAGTAAATAATGAGTGTATTAATTGATAAAGA
CACCAAAGTATTGGTGCAAG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MNLHEYQAKLLLESYGLPIQKGIIAYNGEEAAEAFDKTPTDVAVIKAQVHAGGRGKAGGVKLVKTREEAKEVAESLIGTN
LVTYQTDAEGQPVNFVLVAEDMYPVKTELYLGAVVDRATRRVTFMASTEGGVEIEKVAEETPEKIFSITVDPLVGLLPFQ
AREVGFKLGLEGKQINQFVKLMTGAYKAFVENDFDMIEINPLAVRENGELACVDGKIGVDSNALFRQPKIAALHDPSQEN
ERELKAAEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLYGGKPANFLDVGGGATKDRVVEAFKIILEDSSVQGVLINIF
GGIVRCDMIAEAIIAAVKEVNVTVPVVVRLEGNNAELGAKLLDESDVEIISAQGLSDAAQKIVDAVKAA

Sequences:

>Translated_389_residues
MNLHEYQAKLLLESYGLPIQKGIIAYNGEEAAEAFDKTPTDVAVIKAQVHAGGRGKAGGVKLVKTREEAKEVAESLIGTN
LVTYQTDAEGQPVNFVLVAEDMYPVKTELYLGAVVDRATRRVTFMASTEGGVEIEKVAEETPEKIFSITVDPLVGLLPFQ
AREVGFKLGLEGKQINQFVKLMTGAYKAFVENDFDMIEINPLAVRENGELACVDGKIGVDSNALFRQPKIAALHDPSQEN
ERELKAAEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLYGGKPANFLDVGGGATKDRVVEAFKIILEDSSVQGVLINIF
GGIVRCDMIAEAIIAAVKEVNVTVPVVVRLEGNNAELGAKLLDESDVEIISAQGLSDAAQKIVDAVKAA
>Mature_389_residues
MNLHEYQAKLLLESYGLPIQKGIIAYNGEEAAEAFDKTPTDVAVIKAQVHAGGRGKAGGVKLVKTREEAKEVAESLIGTN
LVTYQTDAEGQPVNFVLVAEDMYPVKTELYLGAVVDRATRRVTFMASTEGGVEIEKVAEETPEKIFSITVDPLVGLLPFQ
AREVGFKLGLEGKQINQFVKLMTGAYKAFVENDFDMIEINPLAVRENGELACVDGKIGVDSNALFRQPKIAALHDPSQEN
ERELKAAEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLYGGKPANFLDVGGGATKDRVVEAFKIILEDSSVQGVLINIF
GGIVRCDMIAEAIIAAVKEVNVTVPVVVRLEGNNAELGAKLLDESDVEIISAQGLSDAAQKIVDAVKAA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=45.3846153846154, Blast_Score=325, Evalue=3e-89,
Organism=Homo sapiens, GI157779135, Length=384, Percent_Identity=43.2291666666667, Blast_Score=294, Evalue=1e-79,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=43.7325905292479, Blast_Score=281, Evalue=6e-76,
Organism=Escherichia coli, GI1786948, Length=387, Percent_Identity=63.5658914728682, Blast_Score=480, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=42.2784810126582, Blast_Score=311, Evalue=6e-85,
Organism=Caenorhabditis elegans, GI17567829, Length=389, Percent_Identity=43.4447300771208, Blast_Score=308, Evalue=3e-84,
Organism=Saccharomyces cerevisiae, GI6321683, Length=394, Percent_Identity=43.1472081218274, Blast_Score=325, Evalue=8e-90,
Organism=Drosophila melanogaster, GI161078106, Length=386, Percent_Identity=45.0777202072539, Blast_Score=310, Evalue=1e-84,
Organism=Drosophila melanogaster, GI24645208, Length=386, Percent_Identity=45.0777202072539, Blast_Score=310, Evalue=1e-84,
Organism=Drosophila melanogaster, GI281361397, Length=389, Percent_Identity=45.2442159383033, Blast_Score=310, Evalue=2e-84,
Organism=Drosophila melanogaster, GI281361395, Length=389, Percent_Identity=45.2442159383033, Blast_Score=310, Evalue=2e-84,
Organism=Drosophila melanogaster, GI21356231, Length=394, Percent_Identity=43.6548223350254, Blast_Score=296, Evalue=2e-80,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_PSYWF (A5WC33)

Other databases:

- EMBL:   CP000713
- RefSeq:   YP_001279174.1
- ProteinModelPortal:   A5WC33
- SMR:   A5WC33
- STRING:   A5WC33
- GeneID:   5206741
- GenomeReviews:   CP000713_GR
- KEGG:   prw:PsycPRwf_0269
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   EGDIGCM
- ProtClustDB:   PRK00696
- BioCyc:   PSP56811:PSYCPRWF_0269-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41700; Mature: 41700

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKLLLESYGLPIQKGIIAYNGEEAAEAFDKTPTDVAVIKAQVHAGGRGKAGGV
CCHHHHHHHHHHHHCCCCHHCCEEEECCCHHHHHHCCCCCCEEEEEEEECCCCCCCCCCE
KLVKTREEAKEVAESLIGTNLVTYQTDAEGQPVNFVLVAEDMYPVKTELYLGAVVDRATR
EEEECHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHH
RVTFMASTEGGVEIEKVAEETPEKIFSITVDPLVGLLPFQAREVGFKLGLEGKQINQFVK
EEEEEEECCCCCCHHHHHHHCCHHHEEEEHHHHHHHCCCCHHHCCEEECCCHHHHHHHHH
LMTGAYKAFVENDFDMIEINPLAVRENGELACVDGKIGVDSNALFRQPKIAALHDPSQEN
HHHHHHHHHHCCCCCEEEECEEEEECCCCEEEECCCCCCCCCHHHCCCCEEEECCCCCCC
ERELKAAEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLYGGKPANFLDVGGGATKDRVV
HHHHHHEEECEEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHH
EAFKIILEDSSVQGVLINIFGGIVRCDMIAEAIIAAVKEVNVTVPVVVRLEGNNAELGAK
HHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCHH
LLDESDVEIISAQGLSDAAQKIVDAVKAA
HCCCCCCEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLHEYQAKLLLESYGLPIQKGIIAYNGEEAAEAFDKTPTDVAVIKAQVHAGGRGKAGGV
CCHHHHHHHHHHHHCCCCHHCCEEEECCCHHHHHHCCCCCCEEEEEEEECCCCCCCCCCE
KLVKTREEAKEVAESLIGTNLVTYQTDAEGQPVNFVLVAEDMYPVKTELYLGAVVDRATR
EEEECHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHH
RVTFMASTEGGVEIEKVAEETPEKIFSITVDPLVGLLPFQAREVGFKLGLEGKQINQFVK
EEEEEEECCCCCCHHHHHHHCCHHHEEEEHHHHHHHCCCCHHHCCEEECCCHHHHHHHHH
LMTGAYKAFVENDFDMIEINPLAVRENGELACVDGKIGVDSNALFRQPKIAALHDPSQEN
HHHHHHHHHHCCCCCEEEECEEEEECCCCEEEECCCCCCCCCHHHCCCCEEEECCCCCCC
ERELKAAEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLYGGKPANFLDVGGGATKDRVV
HHHHHHEEECEEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHH
EAFKIILEDSSVQGVLINIFGGIVRCDMIAEAIIAAVKEVNVTVPVVVRLEGNNAELGAK
HHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCHH
LLDESDVEIISAQGLSDAAQKIVDAVKAA
HCCCCCCEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA