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The map label for this gene is sucD [H]

Identifier: 148652082

GI number: 148652082

Start: 320880

End: 321755

Strand: Direct

Name: sucD [H]

Synonym: PsycPRwf_0270

Alternate gene names: 148652082

Gene position: 320880-321755 (Clockwise)

Preceding gene: 148652081

Following gene: 148652083

Centisome position: 10.77

GC content: 46.8

Gene sequence:

>876_bases
ATGAGTGTATTAATTGATAAAGACACCAAAGTATTGGTGCAAGGTTTTACTGGTAAAAACGGTACTTTCCATTCAGAACA
AGCCATTGAATACGGCACCAAAGTAGTTGGCGGTGTTACCCCAGGTAAAGGCGGTCAAACTCACCTAGGTCTGCCTGTAT
TTAACACCATGGCAGAAGCGATGGAAGCAACTCAAGCTGATGCGTCAGTTATCTATGTACCAGCACCTTTCGTACTAGAC
TCAATCATCGAAGCAGTAGACGCTGGCGTTAAGCTAATCGTTGTTATCACTGAAGGTGTACCTACTTTAGATATGCTAAA
AGCCAAACGCTACATCGAAGAAGCTGGCGATGTGAAAATGGTTGGTCCAAACTGCCCAGGCGTTATCACCCCAGGTCAGT
GCAAAATCGGTATCATGCCAGGCCACATCCATCTGCCAGGTAAAGTAGGTATCATCTCACGTTCTGGTACCTTGACTTAT
GAAGCTGTGGCTCAGACCACTAAGCTTGGCTTCGGTCAGTCAACTTGTATCGGTATCGGCGGTGACCCAATCCCAGGTAT
GAACCAAATCGATTGCTTGAAGATGTTCCAAGAAGATCCTCAAACTGAAGCCATCGTACTTATCGGTGAAATCGGTGGTA
CTGCTGAAGAAGAAGCCGCCGCTTACATCAAAGAGCACGTCACTAAGCCAGTTATCGGTTACATCGCTGGCGTGACTGCC
CCTAAAGGTAAGCGTATGGGCCATGCCGGCGCTATCATCTCTGGTGGTAAAGGTACTGCAGAAGAAAAATTCAAAGCATT
CGAAGATGCGGGCATCGCGTACACTCGTGACCCATCTAAGATTGGTGAGACGGTTAAACAAGTTACTGGTTGGTAA

Upstream 100 bases:

>100_bases
TGATGCTGCACAAAAAATTGTTGATGCTGTAAAAGCGGCATAATTCGCCTATCACAACTGTATCAAACCTATAATAAGTG
AATCCTACTAGGAGTAAATA

Downstream 100 bases:

>100_bases
TTTGCCAGTCTCGGTGTTAACGGTAAGTTAACTCAAAGAGCATCCTTCGGGGTGCTCTTTTTTTTGTCGCATATTTAATT
GTCTGACTAAGTTTTTAGTA

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSVLIDKDTKVLVQGFTGKNGTFHSEQAIEYGTKVVGGVTPGKGGQTHLGLPVFNTMAEAMEATQADASVIYVPAPFVLD
SIIEAVDAGVKLIVVITEGVPTLDMLKAKRYIEEAGDVKMVGPNCPGVITPGQCKIGIMPGHIHLPGKVGIISRSGTLTY
EAVAQTTKLGFGQSTCIGIGGDPIPGMNQIDCLKMFQEDPQTEAIVLIGEIGGTAEEEAAAYIKEHVTKPVIGYIAGVTA
PKGKRMGHAGAIISGGKGTAEEKFKAFEDAGIAYTRDPSKIGETVKQVTGW

Sequences:

>Translated_291_residues
MSVLIDKDTKVLVQGFTGKNGTFHSEQAIEYGTKVVGGVTPGKGGQTHLGLPVFNTMAEAMEATQADASVIYVPAPFVLD
SIIEAVDAGVKLIVVITEGVPTLDMLKAKRYIEEAGDVKMVGPNCPGVITPGQCKIGIMPGHIHLPGKVGIISRSGTLTY
EAVAQTTKLGFGQSTCIGIGGDPIPGMNQIDCLKMFQEDPQTEAIVLIGEIGGTAEEEAAAYIKEHVTKPVIGYIAGVTA
PKGKRMGHAGAIISGGKGTAEEKFKAFEDAGIAYTRDPSKIGETVKQVTGW
>Mature_290_residues
SVLIDKDTKVLVQGFTGKNGTFHSEQAIEYGTKVVGGVTPGKGGQTHLGLPVFNTMAEAMEATQADASVIYVPAPFVLDS
IIEAVDAGVKLIVVITEGVPTLDMLKAKRYIEEAGDVKMVGPNCPGVITPGQCKIGIMPGHIHLPGKVGIISRSGTLTYE
AVAQTTKLGFGQSTCIGIGGDPIPGMNQIDCLKMFQEDPQTEAIVLIGEIGGTAEEEAAAYIKEHVTKPVIGYIAGVTAP
KGKRMGHAGAIISGGKGTAEEKFKAFEDAGIAYTRDPSKIGETVKQVTGW

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=287, Percent_Identity=60.9756097560976, Blast_Score=317, Evalue=7e-87,
Organism=Homo sapiens, GI38569423, Length=258, Percent_Identity=31.3953488372093, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI38569421, Length=258, Percent_Identity=31.3953488372093, Blast_Score=111, Evalue=9e-25,
Organism=Escherichia coli, GI1786949, Length=288, Percent_Identity=77.4305555555556, Blast_Score=451, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17550194, Length=288, Percent_Identity=61.4583333333333, Blast_Score=347, Evalue=6e-96,
Organism=Caenorhabditis elegans, GI17553126, Length=290, Percent_Identity=58.6206896551724, Blast_Score=333, Evalue=6e-92,
Organism=Caenorhabditis elegans, GI17557344, Length=310, Percent_Identity=30.6451612903226, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17551266, Length=310, Percent_Identity=30, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324716, Length=292, Percent_Identity=50.6849315068493, Blast_Score=277, Evalue=1e-75,
Organism=Drosophila melanogaster, GI21356559, Length=288, Percent_Identity=56.25, Blast_Score=332, Evalue=1e-91,
Organism=Drosophila melanogaster, GI28574296, Length=288, Percent_Identity=59.375, Blast_Score=320, Evalue=5e-88,
Organism=Drosophila melanogaster, GI281363475, Length=262, Percent_Identity=31.2977099236641, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281363473, Length=262, Percent_Identity=31.2977099236641, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281363477, Length=262, Percent_Identity=31.2977099236641, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30382; Mature: 30251

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLIDKDTKVLVQGFTGKNGTFHSEQAIEYGTKVVGGVTPGKGGQTHLGLPVFNTMAEA
CCEEECCCCEEEEEECCCCCCCCCCHHHHHHCCCEECCCCCCCCCCEEECCHHHHHHHHH
MEATQADASVIYVPAPFVLDSIIEAVDAGVKLIVVITEGVPTLDMLKAKRYIEEAGDVKM
HHHHCCCCEEEEECCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCEEE
VGPNCPGVITPGQCKIGIMPGHIHLPGKVGIISRSGTLTYEAVAQTTKLGFGQSTCIGIG
ECCCCCCEECCCCEEEEEECCEEECCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECC
GDPIPGMNQIDCLKMFQEDPQTEAIVLIGEIGGTAEEEAAAYIKEHVTKPVIGYIAGVTA
CCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHCCCC
PKGKRMGHAGAIISGGKGTAEEKFKAFEDAGIAYTRDPSKIGETVKQVTGW
CCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVLIDKDTKVLVQGFTGKNGTFHSEQAIEYGTKVVGGVTPGKGGQTHLGLPVFNTMAEA
CEEECCCCEEEEEECCCCCCCCCCHHHHHHCCCEECCCCCCCCCCEEECCHHHHHHHHH
MEATQADASVIYVPAPFVLDSIIEAVDAGVKLIVVITEGVPTLDMLKAKRYIEEAGDVKM
HHHHCCCCEEEEECCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCEEE
VGPNCPGVITPGQCKIGIMPGHIHLPGKVGIISRSGTLTYEAVAQTTKLGFGQSTCIGIG
ECCCCCCEECCCCEEEEEECCEEECCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECC
GDPIPGMNQIDCLKMFQEDPQTEAIVLIGEIGGTAEEEAAAYIKEHVTKPVIGYIAGVTA
CCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHCCCC
PKGKRMGHAGAIISGGKGTAEEKFKAFEDAGIAYTRDPSKIGETVKQVTGW
CCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]