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The map label for this gene is yybO [H]

Identifier: 148550567

GI number: 148550567

Start: 13687

End: 14943

Strand: Reverse

Name: yybO [H]

Synonym: Swit_5128

Alternate gene names: 148550567

Gene position: 14943-13687 (Counterclockwise)

Preceding gene: 148550568

Following gene: 148550564

Centisome position: 4.82

GC content: 65.47

Gene sequence:

>1257_bases
ATGACGAGCAGCGAACCGGGCCGGGACGGCCGCTATAAGTGGCTGGTGCTGGCCATGCTGCTGCTGGTCTATACCTTCAA
TTTTCTGGACCGGCAGATCCTTGGCATCCTGGCCATTCCCATCAAGACCGAACTGGGGCTGAGCGATACGCAGCTGGGTG
CGCTTGGTGGGATCGCCTTCGCGCTCCTCTATTCCACACTGGCGATTCCGCTCGCGCTGCTGGCCGATCGTACCAGCCGC
ACATGGGTCATCACCATCAGCCTGGCGGTCTGGAGCGGCTTTACCGCGCTCTGCGGCATGGCCGGCAACTTCGTTCAGCT
CTTCGCCTTTCGCGTCGGCGTGGGTGTGGGCGAAGCGGGCGGCGTGGCGCCATCCTATGCCGTGATTTCCGATTATTTCC
CGCCGCAGCAACGTGCACGTGCGCTGTCGATCTATTCGCTGGGAATTCCATTGGGGTCGGCGGGCGGCGTGTTGCTGGGC
GGCTATATCGCGCAGCGGGTGGAGTGGCGGACGGCCTTTCTGGTCGTCGGTGCGCTGGGCCTGCTGATCGCGCCGCTGTT
CCGCCTGACCGTGCGCGAGCCGGTGCGGCCGGTTGCCACCGGAGCAGGCGAGCCGGTTTCGGCGGTCTTCGGCATCCTGG
CGAAAAAACGCAGCTTCTGGCTGCTGGCGCTGGGTGCGGCGTGCAGTTCGATGTGCGGCTATGGCGTCGCATTCTGGCTT
CCGGCACTGCTGATGCGCAGCTTCGGCCTTGATCTGCTGGGCGCGGGGCAGTTCCTCGGCGGATTGCTGCTGCTCGGCGG
GGTGGCGGGCGTGCTGCTGGGCGGATGGCTGGGGGACCGGCTGGGCGGACGGGACAAGGCGGCATATGCCTGGATCCCGG
CGGCGAGCTATATTATCGGCATGCCGCTATTCGTCATCGGTGTGCTGTCGCACAGCGTGTCCTTTACCTTCATGATGTTC
ATCGTGCCGCAGGCGCTGGTCTATGTCTGGCTCGGCCCGGTGCTGACCGCGGTGCAGCATCTGGTGCCGCCGCAGATGCG
CGCCAGCGCCTCGGCCAGCTTCCTGCTGATCAACAATCTTGTGGGATTGGGCTTGGGAAGCTGGGCCGTGGGCAGCCTGT
CCGATGCGCTGACGCCCGCTTTCGGTGTGGAGGCACTGCGCTATGCCATTGTGGCCGCGCTCGGCTTCTACCTGCTCGCT
GGCCTGTTCATGGCGCTCGCCGGAAAGTCGCTGCGCAAGGACTGGGTGAGCGCCTGA

Upstream 100 bases:

>100_bases
TTGCTCGCAATAAGTGGCGGTCGCACCTGTTGGGCTGATGGCGACGCCGGTTGCCCTCGCCGCGTCCCCATGAGACAGCA
TGCGTCGCGAGGAGACAGTG

Downstream 100 bases:

>100_bases
CGCGTCCCAGTCCTAACGTTCCTTGGTGGCGCTGAACGTCACGTCGGGATTGCGTTCCTGCTGATAGTTCACGTCCCACG
CGCTTTTCGCCATGAACACC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MTSSEPGRDGRYKWLVLAMLLLVYTFNFLDRQILGILAIPIKTELGLSDTQLGALGGIAFALLYSTLAIPLALLADRTSR
TWVITISLAVWSGFTALCGMAGNFVQLFAFRVGVGVGEAGGVAPSYAVISDYFPPQQRARALSIYSLGIPLGSAGGVLLG
GYIAQRVEWRTAFLVVGALGLLIAPLFRLTVREPVRPVATGAGEPVSAVFGILAKKRSFWLLALGAACSSMCGYGVAFWL
PALLMRSFGLDLLGAGQFLGGLLLLGGVAGVLLGGWLGDRLGGRDKAAYAWIPAASYIIGMPLFVIGVLSHSVSFTFMMF
IVPQALVYVWLGPVLTAVQHLVPPQMRASASASFLLINNLVGLGLGSWAVGSLSDALTPAFGVEALRYAIVAALGFYLLA
GLFMALAGKSLRKDWVSA

Sequences:

>Translated_418_residues
MTSSEPGRDGRYKWLVLAMLLLVYTFNFLDRQILGILAIPIKTELGLSDTQLGALGGIAFALLYSTLAIPLALLADRTSR
TWVITISLAVWSGFTALCGMAGNFVQLFAFRVGVGVGEAGGVAPSYAVISDYFPPQQRARALSIYSLGIPLGSAGGVLLG
GYIAQRVEWRTAFLVVGALGLLIAPLFRLTVREPVRPVATGAGEPVSAVFGILAKKRSFWLLALGAACSSMCGYGVAFWL
PALLMRSFGLDLLGAGQFLGGLLLLGGVAGVLLGGWLGDRLGGRDKAAYAWIPAASYIIGMPLFVIGVLSHSVSFTFMMF
IVPQALVYVWLGPVLTAVQHLVPPQMRASASASFLLINNLVGLGLGSWAVGSLSDALTPAFGVEALRYAIVAALGFYLLA
GLFMALAGKSLRKDWVSA
>Mature_417_residues
TSSEPGRDGRYKWLVLAMLLLVYTFNFLDRQILGILAIPIKTELGLSDTQLGALGGIAFALLYSTLAIPLALLADRTSRT
WVITISLAVWSGFTALCGMAGNFVQLFAFRVGVGVGEAGGVAPSYAVISDYFPPQQRARALSIYSLGIPLGSAGGVLLGG
YIAQRVEWRTAFLVVGALGLLIAPLFRLTVREPVRPVATGAGEPVSAVFGILAKKRSFWLLALGAACSSMCGYGVAFWLP
ALLMRSFGLDLLGAGQFLGGLLLLGGVAGVLLGGWLGDRLGGRDKAAYAWIPAASYIIGMPLFVIGVLSHSVSFTFMMFI
VPQALVYVWLGPVLTAVQHLVPPQMRASASASFLLINNLVGLGLGSWAVGSLSDALTPAFGVEALRYAIVAALGFYLLAG
LFMALAGKSLRKDWVSA

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI215490096, Length=425, Percent_Identity=26.5882352941176, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI14042968, Length=425, Percent_Identity=26.5882352941176, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI215490100, Length=397, Percent_Identity=26.448362720403, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI185136021, Length=256, Percent_Identity=25.78125, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367379, Length=291, Percent_Identity=31.2714776632302, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1789152, Length=353, Percent_Identity=25.7790368271955, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI87082320, Length=298, Percent_Identity=26.510067114094, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17557872, Length=408, Percent_Identity=26.2254901960784, Blast_Score=95, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17539092, Length=461, Percent_Identity=23.8611713665944, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI193209775, Length=434, Percent_Identity=23.963133640553, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71992409, Length=444, Percent_Identity=24.7747747747748, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24654037, Length=386, Percent_Identity=27.4611398963731, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24654041, Length=386, Percent_Identity=27.4611398963731, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24654039, Length=385, Percent_Identity=27.012987012987, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17864456, Length=385, Percent_Identity=27.012987012987, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24654044, Length=240, Percent_Identity=27.9166666666667, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24640209, Length=333, Percent_Identity=27.3273273273273, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44011; Mature: 43880

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSEPGRDGRYKWLVLAMLLLVYTFNFLDRQILGILAIPIKTELGLSDTQLGALGGIAF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHH
ALLYSTLAIPLALLADRTSRTWVITISLAVWSGFTALCGMAGNFVQLFAFRVGVGVGEAG
HHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHCCHHHHHHCCCHHHHHHHHHHHCCCCCCC
GVAPSYAVISDYFPPQQRARALSIYSLGIPLGSAGGVLLGGYIAQRVEWRTAFLVVGALG
CCCCCHHHHHCCCCHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLIAPLFRLTVREPVRPVATGAGEPVSAVFGILAKKRSFWLLALGAACSSMCGYGVAFWL
HHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHCCCHHHEEHHHHHHHHHCCCHHHHH
PALLMRSFGLDLLGAGQFLGGLLLLGGVAGVLLGGWLGDRLGGRDKAAYAWIPAASYIIG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHH
MPLFVIGVLSHSVSFTFMMFIVPQALVYVWLGPVLTAVQHLVPPQMRASASASFLLINNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHH
VGLGLGSWAVGSLSDALTPAFGVEALRYAIVAALGFYLLAGLFMALAGKSLRKDWVSA
HHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
>Mature Secondary Structure 
TSSEPGRDGRYKWLVLAMLLLVYTFNFLDRQILGILAIPIKTELGLSDTQLGALGGIAF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHH
ALLYSTLAIPLALLADRTSRTWVITISLAVWSGFTALCGMAGNFVQLFAFRVGVGVGEAG
HHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHCCHHHHHHCCCHHHHHHHHHHHCCCCCCC
GVAPSYAVISDYFPPQQRARALSIYSLGIPLGSAGGVLLGGYIAQRVEWRTAFLVVGALG
CCCCCHHHHHCCCCHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLIAPLFRLTVREPVRPVATGAGEPVSAVFGILAKKRSFWLLALGAACSSMCGYGVAFWL
HHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHCCCHHHEEHHHHHHHHHCCCHHHHH
PALLMRSFGLDLLGAGQFLGGLLLLGGVAGVLLGGWLGDRLGGRDKAAYAWIPAASYIIG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHH
MPLFVIGVLSHSVSFTFMMFIVPQALVYVWLGPVLTAVQHLVPPQMRASASASFLLINNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHH
VGLGLGSWAVGSLSDALTPAFGVEALRYAIVAALGFYLLAGLFMALAGKSLRKDWVSA
HHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]