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The map label for this gene is cdsA [H]

Identifier: 148360881

GI number: 148360881

Start: 596448

End: 597110

Strand: Direct

Name: cdsA [H]

Synonym: LPC_2841

Alternate gene names: 148360881

Gene position: 596448-597110 (Clockwise)

Preceding gene: 148360882

Following gene: 148360880

Centisome position: 16.68

GC content: 34.84

Gene sequence:

>663_bases
TTGATTCCTGTTGACAATTTAACTGTACAGGCTTGTTTTTTGATATTTTTATTGATGTGCTTTTGGGCCAGTGGCTATTT
CTATCCCTATTGGTTGAGTGTGGGCTTATTGGTTTGGTTATTAAATGGGTTAGCAATTCTTACTTATCCGCGTTCACAAA
ATTATTGGGGTTATCCAATCGTTGTTGCCATAGCTTCTTTGATATTACTACCCTTATTTACTCAAAGTCTTATTCAAATT
TCTTTTTTACAGCAAGGAAAGGAATTACTTGTCTATTTGCTTTTTTTAATTTGGGCTTCTGATATTGGTGCTTATCTCGC
TGGAAAACAATGGGGAAAACATAAATTAATCCCTAAAGTTAGTCCGGGTAAATCTTGGGAAGGTGTTACAGGCGGAGTTA
TTTTAGCCATGATAGTCGCGACTTTGGGCTATTATTATTTTATACCTTACTCAATTTATATATGGTTTGGTTTAGCATTG
TCTACTGTAGTTATTTCAATTTTTGGTGATTTGTTCATCAGTATATTAAAACGGCGTTGTCAATTAAAAGATACTGGAAA
TATTATTCCAGGTCATGGCGGTATATTAGATCGACTGGATAGCCTAATTGCCGCGTTACCATGGTTTTACTTTGGATTAA
CCTACATACCACTGGGAATTTAA

Upstream 100 bases:

>100_bases
CGCCCCCTGGTTTTGCTAGCTAATTTTTAATGCCCCTTCCTGGATTTTATGGGGTATTGTTCTAGTTATACTCCTGCTTG
CAGGACTGGAATGTTTCAAA

Downstream 100 bases:

>100_bases
TTTTCTGGTCGTATCAATCTTTGGATAACGATATGCTTTCAACGTTGCTGTACTTTTTATTAGCATTGGTATTGTTAGTC
ACCATACATGAATACGGCCA

Product: phosphatidate cytidyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MIPVDNLTVQACFLIFLLMCFWASGYFYPYWLSVGLLVWLLNGLAILTYPRSQNYWGYPIVVAIASLILLPLFTQSLIQI
SFLQQGKELLVYLLFLIWASDIGAYLAGKQWGKHKLIPKVSPGKSWEGVTGGVILAMIVATLGYYYFIPYSIYIWFGLAL
STVVISIFGDLFISILKRRCQLKDTGNIIPGHGGILDRLDSLIAALPWFYFGLTYIPLGI

Sequences:

>Translated_220_residues
MIPVDNLTVQACFLIFLLMCFWASGYFYPYWLSVGLLVWLLNGLAILTYPRSQNYWGYPIVVAIASLILLPLFTQSLIQI
SFLQQGKELLVYLLFLIWASDIGAYLAGKQWGKHKLIPKVSPGKSWEGVTGGVILAMIVATLGYYYFIPYSIYIWFGLAL
STVVISIFGDLFISILKRRCQLKDTGNIIPGHGGILDRLDSLIAALPWFYFGLTYIPLGI
>Mature_220_residues
MIPVDNLTVQACFLIFLLMCFWASGYFYPYWLSVGLLVWLLNGLAILTYPRSQNYWGYPIVVAIASLILLPLFTQSLIQI
SFLQQGKELLVYLLFLIWASDIGAYLAGKQWGKHKLIPKVSPGKSWEGVTGGVILAMIVATLGYYYFIPYSIYIWFGLAL
STVVISIFGDLFISILKRRCQLKDTGNIIPGHGGILDRLDSLIAALPWFYFGLTYIPLGI

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=187, Percent_Identity=37.4331550802139, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787677, Length=117, Percent_Identity=41.025641025641, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 24749; Mature: 24749

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPVDNLTVQACFLIFLLMCFWASGYFYPYWLSVGLLVWLLNGLAILTYPRSQNYWGYPI
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHH
VVAIASLILLPLFTQSLIQISFLQQGKELLVYLLFLIWASDIGAYLAGKQWGKHKLIPKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SPGKSWEGVTGGVILAMIVATLGYYYFIPYSIYIWFGLALSTVVISIFGDLFISILKRRC
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLKDTGNIIPGHGGILDRLDSLIAALPWFYFGLTYIPLGI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIPVDNLTVQACFLIFLLMCFWASGYFYPYWLSVGLLVWLLNGLAILTYPRSQNYWGYPI
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHH
VVAIASLILLPLFTQSLIQISFLQQGKELLVYLLFLIWASDIGAYLAGKQWGKHKLIPKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SPGKSWEGVTGGVILAMIVATLGYYYFIPYSIYIWFGLALSTVVISIFGDLFISILKRRC
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLKDTGNIIPGHGGILDRLDSLIAALPWFYFGLTYIPLGI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]