| Definition | Legionella pneumophila str. Corby chromosome, complete genome. |
|---|---|
| Accession | NC_009494 |
| Length | 3,576,470 |
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The map label for this gene is slt [H]
Identifier: 148360683
GI number: 148360683
Start: 824287
End: 826068
Strand: Reverse
Name: slt [H]
Synonym: LPC_2629
Alternate gene names: 148360683
Gene position: 826068-824287 (Counterclockwise)
Preceding gene: 148360682
Following gene: 148360690
Centisome position: 23.1
GC content: 37.43
Gene sequence:
>1782_bases ATGAAAAAATTATTAATTTTTTTATGTGGGCTTCTCTGTTCTTTCAACTTGTTTGCTTTATCTGGACAAGCCTACATGGA CAGGTTTAATCGCTATCTTGCATGGTATGAACAGCTTCCTATTAACCCATCGCCAGAATTTTTGGAATTTGTAAAAGAAA ACACACCGCTTGCTAATAAATTGCGTGACAAATGGTTATATGAACTGGCCAGGATAAAGGATTGGGAAGATTATAATAAG TATTATCAACCTACCAACGACATAAACCTCAGATGCTTTGCGCAAATTGCGAAATTCAATTTAGGATTATACAAGGAGGC TATAGCAGGCTCTATTCCAATCTGGTTATCAGGAGAATCAAGACCCCAGGCATGCAATACCCTATTTGCATTACTGTTAA AGCAGGATAACTTTGATCAGAAATTCATTACGCAACGCATAGCACTTGCACTAGACAAACGTAATGTTCTACTCGCTCGT TACCTGTTAAAACAATACAAAACACCTCACGATACAGAAATAAAAAACTTAACCAGTGTTTATGAGAATCCTTCCAATAT TTCCAAGTTGAACCCTGGCAAATTGAACGATTATTTCTATCTTTATGGATTAAAAAGATTAGTATCCATTAACATGGATA AAGCAGTGAAACTATGGCAAGAGAAAAAAACCAACATCATGTTAAATGAGCGGCAAAAACAAGATTTTCTTGCACATTTG GCATTATACAAGGCCATGAGAAATCATGCCGATGCTCAGGAATGGTTTGCCAAAATCAAACCTGAATACTACACCGATGT GTTAGTCGACTGGCAAATCCGCTTTGCTCTGAAAAATAAAAACTGGAAACAAGTTGAAAAATTAATTAACAACTCACCAA ATAAAGAGATGCCTTGTTGGCAATATTGGTTGGCTCGCTCCCTGGAAGAACAAGGGAAAAAAGCAGAGGCGATTAAAATT TATGAGCCACTAGCTAAAAACAGACATTATTATGGTTTTCTAGCCAGCAAACGCCTGAAAAAAAGACCCAGCTTTGACAA TGAAAAACCAACAACCAACACAGAGATTCTCAAACCCTATCAACCTGTCATAGAACAAGTTAAAAATTTTTACAACTCCA AACAGCTACTGCAAGCATCAAGGTTATTAAATGACTTCATTAGTGAATTACCCAAAGAAGAAGCAAGTGCTCTGGTCTAT TGGATAGCAACCGAACTAAAATGGCACGGAAAATCAGTTTACTTAAGCAATAATGACACACTCAATAATCAATTAGCATT AAGATTTCCATTGGCCTACAAAGACACAATAAAAGTATATGCGTCAAAATACGCCATACCGCCTGAGCTTGTATATGCTA TTATTCGTCAGGAAAGTGGTTTTAGAGAAGATGTAACATCCTCTGCTGGGGCGAAAGGGCTAATGCAAGTCATGCCACAA ACAGCCAGCGCTGTTTCCAAAACCAGCAAAATACCGTATTCGGATCATAAGCAATTGTTTTTATCTCAAAAGAATATCAA TATAGGGATTGCTTATTTACAGCACTTAACCAAGCGCTTCAGCAACCACCCGGTTCTTGTTGCTGCCGCTTACAACGCCG GTCCCAGACAAGTAGTCTATTGGCTTAAAAATCACCCGCCCAAAGAAATAGATATCTGGATTGAAACACTTCCCTGGCAA GAAACACGAAATTATCTAAAAAATGTAATGGCCTTTTATATTGTTTATCAGTACCGTTTAAACCAACAGCCTGATATGAA TAGGTTTCTAACACCTTTGTAA
Upstream 100 bases:
>100_bases ATAGCAGTAATTATAGTGAAACCATTAAACATATGCGTGAACAATTAGCAAGCATTTAAAAGTGCCAAATAATTGCCCTC AAGCCTTATTAAGAGGAATT
Downstream 100 bases:
>100_bases GAGATATTTTCATGGTAGTAAACGTAAATCGTTCTATAGCCAGATCTACGTTTGCGAGCTACCTGTCTGATTTTTGCTAA TTTAACGTAATGGATAAGGA
Product: soluble lytic murein transglycosylase
Products: 1,6-Anhydrobond [C]
Alternate protein names: Exomuramidase; Peptidoglycan lytic exotransglycosylase; Slt70 [H]
Number of amino acids: Translated: 593; Mature: 593
Protein sequence:
>593_residues MKKLLIFLCGLLCSFNLFALSGQAYMDRFNRYLAWYEQLPINPSPEFLEFVKENTPLANKLRDKWLYELARIKDWEDYNK YYQPTNDINLRCFAQIAKFNLGLYKEAIAGSIPIWLSGESRPQACNTLFALLLKQDNFDQKFITQRIALALDKRNVLLAR YLLKQYKTPHDTEIKNLTSVYENPSNISKLNPGKLNDYFYLYGLKRLVSINMDKAVKLWQEKKTNIMLNERQKQDFLAHL ALYKAMRNHADAQEWFAKIKPEYYTDVLVDWQIRFALKNKNWKQVEKLINNSPNKEMPCWQYWLARSLEEQGKKAEAIKI YEPLAKNRHYYGFLASKRLKKRPSFDNEKPTTNTEILKPYQPVIEQVKNFYNSKQLLQASRLLNDFISELPKEEASALVY WIATELKWHGKSVYLSNNDTLNNQLALRFPLAYKDTIKVYASKYAIPPELVYAIIRQESGFREDVTSSAGAKGLMQVMPQ TASAVSKTSKIPYSDHKQLFLSQKNINIGIAYLQHLTKRFSNHPVLVAAAYNAGPRQVVYWLKNHPPKEIDIWIETLPWQ ETRNYLKNVMAFYIVYQYRLNQQPDMNRFLTPL
Sequences:
>Translated_593_residues MKKLLIFLCGLLCSFNLFALSGQAYMDRFNRYLAWYEQLPINPSPEFLEFVKENTPLANKLRDKWLYELARIKDWEDYNK YYQPTNDINLRCFAQIAKFNLGLYKEAIAGSIPIWLSGESRPQACNTLFALLLKQDNFDQKFITQRIALALDKRNVLLAR YLLKQYKTPHDTEIKNLTSVYENPSNISKLNPGKLNDYFYLYGLKRLVSINMDKAVKLWQEKKTNIMLNERQKQDFLAHL ALYKAMRNHADAQEWFAKIKPEYYTDVLVDWQIRFALKNKNWKQVEKLINNSPNKEMPCWQYWLARSLEEQGKKAEAIKI YEPLAKNRHYYGFLASKRLKKRPSFDNEKPTTNTEILKPYQPVIEQVKNFYNSKQLLQASRLLNDFISELPKEEASALVY WIATELKWHGKSVYLSNNDTLNNQLALRFPLAYKDTIKVYASKYAIPPELVYAIIRQESGFREDVTSSAGAKGLMQVMPQ TASAVSKTSKIPYSDHKQLFLSQKNINIGIAYLQHLTKRFSNHPVLVAAAYNAGPRQVVYWLKNHPPKEIDIWIETLPWQ ETRNYLKNVMAFYIVYQYRLNQQPDMNRFLTPL >Mature_593_residues MKKLLIFLCGLLCSFNLFALSGQAYMDRFNRYLAWYEQLPINPSPEFLEFVKENTPLANKLRDKWLYELARIKDWEDYNK YYQPTNDINLRCFAQIAKFNLGLYKEAIAGSIPIWLSGESRPQACNTLFALLLKQDNFDQKFITQRIALALDKRNVLLAR YLLKQYKTPHDTEIKNLTSVYENPSNISKLNPGKLNDYFYLYGLKRLVSINMDKAVKLWQEKKTNIMLNERQKQDFLAHL ALYKAMRNHADAQEWFAKIKPEYYTDVLVDWQIRFALKNKNWKQVEKLINNSPNKEMPCWQYWLARSLEEQGKKAEAIKI YEPLAKNRHYYGFLASKRLKKRPSFDNEKPTTNTEILKPYQPVIEQVKNFYNSKQLLQASRLLNDFISELPKEEASALVY WIATELKWHGKSVYLSNNDTLNNQLALRFPLAYKDTIKVYASKYAIPPELVYAIIRQESGFREDVTSSAGAKGLMQVMPQ TASAVSKTSKIPYSDHKQLFLSQKNINIGIAYLQHLTKRFSNHPVLVAAAYNAGPRQVVYWLKNHPPKEIDIWIETLPWQ ETRNYLKNVMAFYIVYQYRLNQQPDMNRFLTPL
Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]
COG id: COG0741
COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
Gene ontology:
Cell location: Periplasm. Note=Tightly associated with the murein sacculus (By similarity) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transglycosylase slt family [H]
Homologues:
Organism=Escherichia coli, GI87082441, Length=563, Percent_Identity=30.0177619893428, Blast_Score=214, Evalue=2e-56,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR016026 - InterPro: IPR008258 - InterPro: IPR012289 - InterPro: IPR008939 - InterPro: IPR000189 [H]
Pfam domain/function: PF01464 SLT [H]
EC number: 3.2.1.- [C]
Molecular weight: Translated: 69702; Mature: 69702
Theoretical pI: Translated: 9.91; Mature: 9.91
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKLLIFLCGLLCSFNLFALSGQAYMDRFNRYLAWYEQLPINPSPEFLEFVKENTPLANK CHHHHHHHHHHHHCCCHHEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHH LRDKWLYELARIKDWEDYNKYYQPTNDINLRCFAQIAKFNLGLYKEAIAGSIPIWLSGES HHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCC RPQACNTLFALLLKQDNFDQKFITQRIALALDKRNVLLARYLLKQYKTPHDTEIKNLTSV CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHH YENPSNISKLNPGKLNDYFYLYGLKRLVSINMDKAVKLWQEKKTNIMLNERQKQDFLAHL HCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEECHHHHHHHHHHH ALYKAMRNHADAQEWFAKIKPEYYTDVLVDWQIRFALKNKNWKQVEKLINNSPNKEMPCW HHHHHHHCCCCHHHHHHHCCCCHHHHEEEEEEEEEEECCCCHHHHHHHHCCCCCCCCCHH QYWLARSLEEQGKKAEAIKIYEPLAKNRHYYGFLASKRLKKRPSFDNEKPTTNTEILKPY HHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHCCCCCCCCCCCCCCHHCCCH QPVIEQVKNFYNSKQLLQASRLLNDFISELPKEEASALVYWIATELKWHGKSVYLSNNDT HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEEEEEHHEECCCEEEECCCCC LNNQLALRFPLAYKDTIKVYASKYAIPPELVYAIIRQESGFREDVTSSAGAKGLMQVMPQ CCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHH TASAVSKTSKIPYSDHKQLFLSQKNINIGIAYLQHLTKRFSNHPVLVAAAYNAGPRQVVY HHHHHHHHCCCCCCCCHHHEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHEEE WLKNHPPKEIDIWIETLPWQETRNYLKNVMAFYIVYQYRLNQQPDMNRFLTPL HHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCC >Mature Secondary Structure MKKLLIFLCGLLCSFNLFALSGQAYMDRFNRYLAWYEQLPINPSPEFLEFVKENTPLANK CHHHHHHHHHHHHCCCHHEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHH LRDKWLYELARIKDWEDYNKYYQPTNDINLRCFAQIAKFNLGLYKEAIAGSIPIWLSGES HHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCC RPQACNTLFALLLKQDNFDQKFITQRIALALDKRNVLLARYLLKQYKTPHDTEIKNLTSV CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHH YENPSNISKLNPGKLNDYFYLYGLKRLVSINMDKAVKLWQEKKTNIMLNERQKQDFLAHL HCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEECHHHHHHHHHHH ALYKAMRNHADAQEWFAKIKPEYYTDVLVDWQIRFALKNKNWKQVEKLINNSPNKEMPCW HHHHHHHCCCCHHHHHHHCCCCHHHHEEEEEEEEEEECCCCHHHHHHHHCCCCCCCCCHH QYWLARSLEEQGKKAEAIKIYEPLAKNRHYYGFLASKRLKKRPSFDNEKPTTNTEILKPY HHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHCCCCCCCCCCCCCCHHCCCH QPVIEQVKNFYNSKQLLQASRLLNDFISELPKEEASALVYWIATELKWHGKSVYLSNNDT HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEEEEEHHEECCCEEEECCCCC LNNQLALRFPLAYKDTIKVYASKYAIPPELVYAIIRQESGFREDVTSSAGAKGLMQVMPQ CCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHH TASAVSKTSKIPYSDHKQLFLSQKNINIGIAYLQHLTKRFSNHPVLVAAAYNAGPRQVVY HHHHHHHHCCCCCCCCHHHEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHEEE WLKNHPPKEIDIWIETLPWQETRNYLKNVMAFYIVYQYRLNQQPDMNRFLTPL HHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]
Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]
General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]