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The map label for this gene is acdA [H]

Identifier: 148359504

GI number: 148359504

Start: 2276576

End: 2277703

Strand: Reverse

Name: acdA [H]

Synonym: LPC_1414

Alternate gene names: 148359504

Gene position: 2277703-2276576 (Counterclockwise)

Preceding gene: 148359505

Following gene: 148359503

Centisome position: 63.69

GC content: 38.48

Gene sequence:

>1128_bases
TTGCCAAATTACCAGCCTCAATACGTGAAGCAACAGCGACTATTTAACCAATTTATAGAAAATTGCCTTCACTCCCATGC
AAAAATTTTTGATAAGGAACAAAACATTCCGCGCGACTTTTTTTATACATTAGCCCAAAATGGTTTTTTGGGCGCTGGTA
TTCCCAAACAATTTGGCGGGCAGCAATGGGATGAATTGACCATTGGTATCATGCATGAATCCTTTGCTAAAGAACTTTGT
TCTTTGGCAAATATCCTAACAGTATTGGGCATGGTGAGTAAGTCACTTTTGCAATTTGGTTCAAAAGCTCAGAAACAAAT
CTGGCTGCCACGGATTGCCTCAGGAGAAACTTTAGCTGCATTGGCTTTAACTGAATCTAATATCGGTAGTGATTTGGAGC
ATGTTGAAACTCAGTTGCTGGATGCAGGTGATGAATTCATTTTAAAAGGAAGTAAAAAATACATTACCTTAGGGCAAATA
GCTGATTTGTTTTTAGTTTTAGCAAATTGCCAAGGCCAACTGACTGCGGTTTTAGTTGAAAAGGACACGTCAGGCTTAAT
CATTACACCCATGTCTAATTTTTTAGGATTACGTTCTAATATGTTGGCAGAAATTTTTTTTGATAATTGCCGAATTCCTA
AAACAAATCTGTTGGGTAATATCGGTATCGGTTTTAACTGTGTTATTCAAACTGCTTTGGATGAAGGACGTTATACAACA
GCGTATGGATGTGTTGGTTTAGGGCAAGCTTGCCTGGATGCGGCTCTTGGCTATACTCAAAAAAGAAAACAATTCGATCG
CAGATTAGACGAACATCAGCTCATTCAAAAAATGATAACTGAAATGGTGGCGCAGGTTAAAGCCGCCCGGGAATTGTGTT
TTTATGCCGGAGAACTTAGACAGCAAAAAAATCCAGCATACATAGCTGAAACATTAATTGCAAAATACGCGGCTTCAAAA
ATGGCCGTTTTTGTATCTAATCATGCTTTACAAATATTTGGCGCAGCTGGCTTTGAAGAAACTTATCCTGTTGAGCGATA
TTACAGAGATGCCAAGGTAATGGAGATCATTGAAGGTACCTCACAAATGCACGAGATACTCATTTCAAAGCTTTGCAACA
ATAAATAG

Upstream 100 bases:

>100_bases
AACAAAAAAGGGATTTTATCAATATGAATAGGGGGTAGTTTACCATTCGCTATTTCAACCCGGATGGTTAAATTGTAAAC
AAACACTAGGGAGAGCAATT

Downstream 100 bases:

>100_bases
AGGATATTATTAAACAATGGGATCCCCTGATCAGTACACGACAATTTGCACCTTATTTGAGGAGAAGGTAAAGCGATACC
CGGAAAATACAGCAGTTTAT

Product: acyl CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MPNYQPQYVKQQRLFNQFIENCLHSHAKIFDKEQNIPRDFFYTLAQNGFLGAGIPKQFGGQQWDELTIGIMHESFAKELC
SLANILTVLGMVSKSLLQFGSKAQKQIWLPRIASGETLAALALTESNIGSDLEHVETQLLDAGDEFILKGSKKYITLGQI
ADLFLVLANCQGQLTAVLVEKDTSGLIITPMSNFLGLRSNMLAEIFFDNCRIPKTNLLGNIGIGFNCVIQTALDEGRYTT
AYGCVGLGQACLDAALGYTQKRKQFDRRLDEHQLIQKMITEMVAQVKAARELCFYAGELRQQKNPAYIAETLIAKYAASK
MAVFVSNHALQIFGAAGFEETYPVERYYRDAKVMEIIEGTSQMHEILISKLCNNK

Sequences:

>Translated_375_residues
MPNYQPQYVKQQRLFNQFIENCLHSHAKIFDKEQNIPRDFFYTLAQNGFLGAGIPKQFGGQQWDELTIGIMHESFAKELC
SLANILTVLGMVSKSLLQFGSKAQKQIWLPRIASGETLAALALTESNIGSDLEHVETQLLDAGDEFILKGSKKYITLGQI
ADLFLVLANCQGQLTAVLVEKDTSGLIITPMSNFLGLRSNMLAEIFFDNCRIPKTNLLGNIGIGFNCVIQTALDEGRYTT
AYGCVGLGQACLDAALGYTQKRKQFDRRLDEHQLIQKMITEMVAQVKAARELCFYAGELRQQKNPAYIAETLIAKYAASK
MAVFVSNHALQIFGAAGFEETYPVERYYRDAKVMEIIEGTSQMHEILISKLCNNK
>Mature_374_residues
PNYQPQYVKQQRLFNQFIENCLHSHAKIFDKEQNIPRDFFYTLAQNGFLGAGIPKQFGGQQWDELTIGIMHESFAKELCS
LANILTVLGMVSKSLLQFGSKAQKQIWLPRIASGETLAALALTESNIGSDLEHVETQLLDAGDEFILKGSKKYITLGQIA
DLFLVLANCQGQLTAVLVEKDTSGLIITPMSNFLGLRSNMLAEIFFDNCRIPKTNLLGNIGIGFNCVIQTALDEGRYTTA
YGCVGLGQACLDAALGYTQKRKQFDRRLDEHQLIQKMITEMVAQVKAARELCFYAGELRQQKNPAYIAETLIAKYAASKM
AVFVSNHALQIFGAAGFEETYPVERYYRDAKVMEIIEGTSQMHEILISKLCNNK

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=358, Percent_Identity=34.9162011173184, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI4501859, Length=347, Percent_Identity=32.8530259365994, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI21361497, Length=364, Percent_Identity=30.4945054945055, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI187960098, Length=377, Percent_Identity=30.2387267904509, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI4557231, Length=377, Percent_Identity=30.2387267904509, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI76496475, Length=385, Percent_Identity=27.012987012987, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI4557235, Length=385, Percent_Identity=27.012987012987, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI226958412, Length=383, Percent_Identity=29.5039164490862, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI7656849, Length=345, Percent_Identity=28.4057971014493, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI226958414, Length=349, Percent_Identity=30.0859598853868, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI4501857, Length=374, Percent_Identity=25.668449197861, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI4503943, Length=363, Percent_Identity=26.7217630853994, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI7669494, Length=351, Percent_Identity=26.7806267806268, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI211971008, Length=289, Percent_Identity=26.9896193771626, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI48976061, Length=289, Percent_Identity=26.9896193771626, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI38505218, Length=282, Percent_Identity=26.5957446808511, Blast_Score=93, Evalue=5e-19,
Organism=Escherichia coli, GI87081958, Length=350, Percent_Identity=25.1428571428571, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1786223, Length=345, Percent_Identity=23.1884057971014, Blast_Score=99, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17508101, Length=363, Percent_Identity=30.8539944903581, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17506239, Length=336, Percent_Identity=32.1428571428571, Blast_Score=188, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17534899, Length=363, Percent_Identity=32.2314049586777, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17570075, Length=363, Percent_Identity=31.9559228650138, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17569725, Length=369, Percent_Identity=31.4363143631436, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17538396, Length=367, Percent_Identity=30.2452316076294, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17533517, Length=361, Percent_Identity=27.9778393351801, Blast_Score=160, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI71985184, Length=351, Percent_Identity=28.4900284900285, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71990804, Length=280, Percent_Identity=30, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17505929, Length=376, Percent_Identity=27.1276595744681, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI71985192, Length=276, Percent_Identity=28.9855072463768, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17551932, Length=375, Percent_Identity=26.6666666666667, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=31.0344827586207, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17534353, Length=288, Percent_Identity=26.0416666666667, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71982178, Length=258, Percent_Identity=28.6821705426357, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17531909, Length=238, Percent_Identity=28.1512605042017, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17562446, Length=292, Percent_Identity=25.6849315068493, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17531913, Length=181, Percent_Identity=23.7569060773481, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356377, Length=364, Percent_Identity=34.3406593406593, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24660351, Length=368, Percent_Identity=32.8804347826087, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24666513, Length=349, Percent_Identity=31.5186246418338, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24646207, Length=363, Percent_Identity=30.3030303030303, Blast_Score=171, Evalue=6e-43,
Organism=Drosophila melanogaster, GI21355753, Length=371, Percent_Identity=31.5363881401617, Blast_Score=154, Evalue=7e-38,
Organism=Drosophila melanogaster, GI19920834, Length=364, Percent_Identity=27.4725274725275, Blast_Score=144, Evalue=7e-35,
Organism=Drosophila melanogaster, GI281363737, Length=386, Percent_Identity=26.4248704663212, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41910; Mature: 41779

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNYQPQYVKQQRLFNQFIENCLHSHAKIFDKEQNIPRDFFYTLAQNGFLGAGIPKQFGG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHCC
QQWDELTIGIMHESFAKELCSLANILTVLGMVSKSLLQFGSKAQKQIWLPRIASGETLAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCEEE
LALTESNIGSDLEHVETQLLDAGDEFILKGSKKYITLGQIADLFLVLANCQGQLTAVLVE
EEEECCCCCCHHHHHHHHHHHCCCHHEEECCCCEEEHHHHHHHHHHHHCCCCCEEEEEEE
KDTSGLIITPMSNFLGLRSNMLAEIFFDNCRIPKTNLLGNIGIGFNCVIQTALDEGRYTT
ECCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHCCCCEEE
AYGCVGLGQACLDAALGYTQKRKQFDRRLDEHQLIQKMITEMVAQVKAARELCFYAGELR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQKNPAYIAETLIAKYAASKMAVFVSNHALQIFGAAGFEETYPVERYYRDAKVMEIIEGT
HCCCHHHHHHHHHHHHHHHHHHHEEECCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
SQMHEILISKLCNNK
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
PNYQPQYVKQQRLFNQFIENCLHSHAKIFDKEQNIPRDFFYTLAQNGFLGAGIPKQFGG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHCC
QQWDELTIGIMHESFAKELCSLANILTVLGMVSKSLLQFGSKAQKQIWLPRIASGETLAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCEEE
LALTESNIGSDLEHVETQLLDAGDEFILKGSKKYITLGQIADLFLVLANCQGQLTAVLVE
EEEECCCCCCHHHHHHHHHHHCCCHHEEECCCCEEEHHHHHHHHHHHHCCCCCEEEEEEE
KDTSGLIITPMSNFLGLRSNMLAEIFFDNCRIPKTNLLGNIGIGFNCVIQTALDEGRYTT
ECCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHCCCCEEE
AYGCVGLGQACLDAALGYTQKRKQFDRRLDEHQLIQKMITEMVAQVKAARELCFYAGELR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQKNPAYIAETLIAKYAASKMAVFVSNHALQIFGAAGFEETYPVERYYRDAKVMEIIEGT
HCCCHHHHHHHHHHHHHHHHHHHEEECCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
SQMHEILISKLCNNK
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]