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The map label for this gene is nhaR [H]

Identifier: 147674750

GI number: 147674750

Start: 214833

End: 215723

Strand: Direct

Name: nhaR [H]

Synonym: VC0395_A0209

Alternate gene names: 147674750

Gene position: 214833-215723 (Clockwise)

Preceding gene: 147673512

Following gene: 147675700

Centisome position: 7.1

GC content: 43.77

Gene sequence:

>891_bases
ATGTCTCATCTTAACTATAACCACCTCTATTATTTCTGGATGGTGTGTAAACAAGGCTCGGTAACCAAAGCGGCCGATGC
TCTGTTTTTAACGCCCCAAACCGTGACGGGGCAGATCAAAGCTTTGGAAGAACGACTTGATGGTAAGTTGACGAAACGTA
ATGGCCGCAGTATTGAGCCGACTGAATTGGGACAGTTGGTCTTTAAATACGCTGATCGTATGTTTGGCTTGAGTTATGAA
ATGTTGGATATCGTTAACTATAGCCAGCGTTCAAACTTGCTGTTTGATGTGGGAGTGGCAGACGCCTTATCCAAAAGATT
GGTGAGCAAAATATTGCTGACCTCAGTACCCGGTGATAACCGGATTCATCTACGCTGCTTTGAATCAACCCATGAGATGC
TATTGGAACAGTTAGCACAGCATAAGTTGGATATGATCTTATCTGATTGCCCAGTGGATTCGAGCCAAAGTCCCGGCTTA
TTTAGTAAAAAACTCGGTGAGAGTCGCATGAGTTTTTTCAGCTTTGGTGACGTGGATTTTGCGCCATTCCCCGCGGTGTT
GCAGAGTAAAAAATTGTTAGTTCCAGGCAGTCGAACCGCAATGGGGCGTAAAGTGCGGCAGTGGTTTGATCGTCAAGGGT
TACAACCACATATTCTCGGTGAATTTGATGACTCTGCTTTAATGAAAGCGTTTGCCATCTATCACAGTGATGCCGTGTTT
ATGGCTCCTTCTTTTTATGTCTCAGAAGTGGATGCGGAATCATCATTGAAACTCATCGGACATGTGGATGAGATTAAAGA
GGAGTATTATGTCATCTTCGCTGAACGCATGATCCAGCACCCAGCAGTAAAAAATGTCTGTGATGCTGATTTTACTAACT
TATTTTTGTGA

Upstream 100 bases:

>100_bases
CTAACTAAACGGTTTATTGTTTCGGTTTATCCGAACTTATTGTTGTAAAAGATCGCATCTGTTATAAGGAAAACGGGATT
TCTAGCGGGTAGTCGATTTC

Downstream 100 bases:

>100_bases
ATAATTATCACTGTTAAGTCTTTGATCACTACCCAATGATAAGTGAAAACAATAAACTAGCGTTCTTGATTAGTTTTTTA
TCATTATCAGCGAGTTTTCT

Product: transcriptional activator NhaR

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSHLNYNHLYYFWMVCKQGSVTKAADALFLTPQTVTGQIKALEERLDGKLTKRNGRSIEPTELGQLVFKYADRMFGLSYE
MLDIVNYSQRSNLLFDVGVADALSKRLVSKILLTSVPGDNRIHLRCFESTHEMLLEQLAQHKLDMILSDCPVDSSQSPGL
FSKKLGESRMSFFSFGDVDFAPFPAVLQSKKLLVPGSRTAMGRKVRQWFDRQGLQPHILGEFDDSALMKAFAIYHSDAVF
MAPSFYVSEVDAESSLKLIGHVDEIKEEYYVIFAERMIQHPAVKNVCDADFTNLFL

Sequences:

>Translated_296_residues
MSHLNYNHLYYFWMVCKQGSVTKAADALFLTPQTVTGQIKALEERLDGKLTKRNGRSIEPTELGQLVFKYADRMFGLSYE
MLDIVNYSQRSNLLFDVGVADALSKRLVSKILLTSVPGDNRIHLRCFESTHEMLLEQLAQHKLDMILSDCPVDSSQSPGL
FSKKLGESRMSFFSFGDVDFAPFPAVLQSKKLLVPGSRTAMGRKVRQWFDRQGLQPHILGEFDDSALMKAFAIYHSDAVF
MAPSFYVSEVDAESSLKLIGHVDEIKEEYYVIFAERMIQHPAVKNVCDADFTNLFL
>Mature_295_residues
SHLNYNHLYYFWMVCKQGSVTKAADALFLTPQTVTGQIKALEERLDGKLTKRNGRSIEPTELGQLVFKYADRMFGLSYEM
LDIVNYSQRSNLLFDVGVADALSKRLVSKILLTSVPGDNRIHLRCFESTHEMLLEQLAQHKLDMILSDCPVDSSQSPGLF
SKKLGESRMSFFSFGDVDFAPFPAVLQSKKLLVPGSRTAMGRKVRQWFDRQGLQPHILGEFDDSALMKAFAIYHSDAVFM
APSFYVSEVDAESSLKLIGHVDEIKEEYYVIFAERMIQHPAVKNVCDADFTNLFL

Specific function: Plays a role in the positive regulation of nhaA (Probable) [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=295, Percent_Identity=62.7118644067797, Blast_Score=397, Evalue=1e-112,
Organism=Escherichia coli, GI1788297, Length=248, Percent_Identity=25.4032258064516, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33574; Mature: 33443

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHLNYNHLYYFWMVCKQGSVTKAADALFLTPQTVTGQIKALEERLDGKLTKRNGRSIEP
CCCCCCCCEEEEEEEECCCCCCHHCCEEEECCCHHHHHHHHHHHHHCCCEECCCCCCCCH
TELGQLVFKYADRMFGLSYEMLDIVNYSQRSNLLFDVGVADALSKRLVSKILLTSVPGDN
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCC
RIHLRCFESTHEMLLEQLAQHKLDMILSDCPVDSSQSPGLFSKKLGESRMSFFSFGDVDF
EEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
APFPAVLQSKKLLVPGSRTAMGRKVRQWFDRQGLQPHILGEFDDSALMKAFAIYHSDAVF
CCCHHHHCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCEEE
MAPSFYVSEVDAESSLKLIGHVDEIKEEYYVIFAERMIQHPAVKNVCDADFTNLFL
ECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHCC
>Mature Secondary Structure 
SHLNYNHLYYFWMVCKQGSVTKAADALFLTPQTVTGQIKALEERLDGKLTKRNGRSIEP
CCCCCCCEEEEEEEECCCCCCHHCCEEEECCCHHHHHHHHHHHHHCCCEECCCCCCCCH
TELGQLVFKYADRMFGLSYEMLDIVNYSQRSNLLFDVGVADALSKRLVSKILLTSVPGDN
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCC
RIHLRCFESTHEMLLEQLAQHKLDMILSDCPVDSSQSPGLFSKKLGESRMSFFSFGDVDF
EEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
APFPAVLQSKKLLVPGSRTAMGRKVRQWFDRQGLQPHILGEFDDSALMKAFAIYHSDAVF
CCCHHHHCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCEEE
MAPSFYVSEVDAESSLKLIGHVDEIKEEYYVIFAERMIQHPAVKNVCDADFTNLFL
ECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]