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The map label for this gene is ptrB [H]

Identifier: 146343739

GI number: 146343739

Start: 7281036

End: 7283135

Strand: Direct

Name: ptrB [H]

Synonym: BRADO6986

Alternate gene names: 146343739

Gene position: 7281036-7283135 (Clockwise)

Preceding gene: 146343738

Following gene: 146343745

Centisome position: 97.65

GC content: 65.9

Gene sequence:

>2100_bases
ATGACCGACAGCAGCACCAAGGCGCCGGTGGCGCCACGCCGTCCGTATTCTTTCACCCGCCACGGCATCACCGTGCAGGA
CGATTACGCCTGGCTGAAGGATGAGCGCTGGCAGGAGGTGCTGCACGATCCCAGGCTGCTCGACGCGGATATTCGCGCCT
ATCTCGAGGCCGAGAACGGATATGCCGAGTCCGTGCTCGGCCACACCGCGCCCCTGCAAAAGACAATCGTGGCGGAGATG
CGCGGCCGCATCAAGGAAGACGACTCCTCGGTGCCGTCGCCGGACGGTCCCTATGCCTATTTCCGCAAGTATCGCGAGGG
CGGCCAGCACGAATTGTTCTGCCGCACGCTGCGCCATGGCGGCGCGGAAACCATCGGGCTCGACGGCGATGCGCTGGCGC
GCGGCCACGACTACTTCAAGTTCGGCGGCAGCCGGCATTCGCATGACCACAAGCTCGTGGCGTGGAGCGCCGACACCAAG
GGCTCGGAATATTTCACCATCCGCGTCCGCGACTGGGACAGCGGCGACGAGCTCGCCGATGTCGTCGAGGAGACCGACGG
CGGCGTGGTGTGGTCGCGCGACTGCAAGAGCTTCTTCTACGTCAAGCTCGACGACAACCACCGGCCGATGCAGGTCTGGC
GCCACAAGCTCGGCACCAAGCAGGCCGACGACGTGCTGGTCTACGAGGAGAAGGACACTGGCTGGTTCACGCATGTGCAC
GAGTCGACCTCCGGCCGGTTCTGCGTCATCGCGGGCGGCGATCATGAGACGTCGGAGCAGCGGCTGATCGATCTCGATGC
GCCCGAAGCGCCGCCGCGGCTCGTCGCCGCGCGCGAGAATGGCGTGCAATACTCGATCGCGGATCGCGGCAACGAGCTGT
TCATCCTGACCAATGCCGACGGCGCGATCGACTTCAAGATCGTGACGGCGCCGCTGGCGGCGCCCGAGCGCGCCAATTGG
CGCGACTTCATCCCGCATCGCGCCGGCATCTACGTGCTCGATCACGATCTGTATTCAGGCCATCTGGTGCGGCTGGAGCG
CGCCAATGCGCTGCCGTCGATCGTGATCCGCGACCTCACATCAGGCGAAGAGCACGCGATCGCCTTCGCCGAGGGCGCCT
ATTCGCTGGATGCGATGGGATCCTACGAGTTCGACACCACCAACCTGCGCTTTGCCTATTCGTCGATGACCACGCCGTCG
GAGGTGTGGGACTACGACATGGTCACGCGCGCAAAGACCTTGCGCAAGCGCCAGGAGATTCCATCGGGGCACAATCCGGC
GGACTACGTCACGACGCGCATCATGGCCAGGGCGGAGGACGGTGCCGAGGTGCCGGTGTCGCTGCTGCACCGGCGCGACT
TCAAGGCCGACGGCTCGGCGCCGCTGCTGCTCTACGGTTACGGCTCCTACGGCCACGCGATGCCGGCGTCGTTCTCCGCC
AACCGGCTGTCGCTTGTCGATCGCGGCTTCGTCTATGCCATCGCGCATATCCGCGGCGGCACCGACAAGGGCTGGGGCTG
GTATCTCGAAGGCAAGCGCGAGAAGAAGACCAACAGCTTTGACGATTTCGCGGCCTGCGCCCGCGCGCTGATCGCGGCAA
ACTACACCAGCGCGAAGCGCATCGTCGGCCATGGCGGCAGCGCCGGCGGCATGCTGATGGGCGCGGTCGCCAATCGCTCG
GGCGAATTGTTCGCCGGCATCGTCGCCGAGGTGCCGTTCGTCGACGTGCTCAACACGATGCTCGACGACACCCTGCCGCT
GACGCCGCCCGAATGGCCCGAATGGGGCAACCCGATCGAGAGCGAAAAGGATTTCCGTACGATCCTGTCCTACTCGCCTT
ATGACAACGTCGCCGCCAAGCACTATCCCGCGATCCTCGCGATGGCCGGCCTCACCGACCCGCGCGTCACCTATTGGGAG
CCCGCGAAATGGATCGCGCGGCTGCGCGCGACGATGACATCAGGCGGCCCGGTGGTGTTGCGCACCAACATGGGCGCCGG
CCACGGCGGCGCCTCCGGCCGCTTCAACCGGCTGGACGAAGTCGCGATCGTCTATGCGTTTGCGCTGTGGGCAGTGGGGA
TGGCGGACAGGACGGCATGA

Upstream 100 bases:

>100_bases
TCGAAATGGCCCTCGTGGCGTTGAAGATCCCGCATGGCCGCGGCGGCCTGGATGCAGCGATCCAATGGCTCGGCGAGAGT
GTGACCGCATAAGGACCGAC

Downstream 100 bases:

>100_bases
GCGGCGACCGGCAAGCGTGAACTGATTGCCCGGCAGCTCACCGCATCAACGGTGTCGTCGTCCCGGCCTTGAGCCGGGAC
CCATAACCACCGTCGGTGGT

Product: peptidase S9A family/protease II

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 699; Mature: 698

Protein sequence:

>699_residues
MTDSSTKAPVAPRRPYSFTRHGITVQDDYAWLKDERWQEVLHDPRLLDADIRAYLEAENGYAESVLGHTAPLQKTIVAEM
RGRIKEDDSSVPSPDGPYAYFRKYREGGQHELFCRTLRHGGAETIGLDGDALARGHDYFKFGGSRHSHDHKLVAWSADTK
GSEYFTIRVRDWDSGDELADVVEETDGGVVWSRDCKSFFYVKLDDNHRPMQVWRHKLGTKQADDVLVYEEKDTGWFTHVH
ESTSGRFCVIAGGDHETSEQRLIDLDAPEAPPRLVAARENGVQYSIADRGNELFILTNADGAIDFKIVTAPLAAPERANW
RDFIPHRAGIYVLDHDLYSGHLVRLERANALPSIVIRDLTSGEEHAIAFAEGAYSLDAMGSYEFDTTNLRFAYSSMTTPS
EVWDYDMVTRAKTLRKRQEIPSGHNPADYVTTRIMARAEDGAEVPVSLLHRRDFKADGSAPLLLYGYGSYGHAMPASFSA
NRLSLVDRGFVYAIAHIRGGTDKGWGWYLEGKREKKTNSFDDFAACARALIAANYTSAKRIVGHGGSAGGMLMGAVANRS
GELFAGIVAEVPFVDVLNTMLDDTLPLTPPEWPEWGNPIESEKDFRTILSYSPYDNVAAKHYPAILAMAGLTDPRVTYWE
PAKWIARLRATMTSGGPVVLRTNMGAGHGGASGRFNRLDEVAIVYAFALWAVGMADRTA

Sequences:

>Translated_699_residues
MTDSSTKAPVAPRRPYSFTRHGITVQDDYAWLKDERWQEVLHDPRLLDADIRAYLEAENGYAESVLGHTAPLQKTIVAEM
RGRIKEDDSSVPSPDGPYAYFRKYREGGQHELFCRTLRHGGAETIGLDGDALARGHDYFKFGGSRHSHDHKLVAWSADTK
GSEYFTIRVRDWDSGDELADVVEETDGGVVWSRDCKSFFYVKLDDNHRPMQVWRHKLGTKQADDVLVYEEKDTGWFTHVH
ESTSGRFCVIAGGDHETSEQRLIDLDAPEAPPRLVAARENGVQYSIADRGNELFILTNADGAIDFKIVTAPLAAPERANW
RDFIPHRAGIYVLDHDLYSGHLVRLERANALPSIVIRDLTSGEEHAIAFAEGAYSLDAMGSYEFDTTNLRFAYSSMTTPS
EVWDYDMVTRAKTLRKRQEIPSGHNPADYVTTRIMARAEDGAEVPVSLLHRRDFKADGSAPLLLYGYGSYGHAMPASFSA
NRLSLVDRGFVYAIAHIRGGTDKGWGWYLEGKREKKTNSFDDFAACARALIAANYTSAKRIVGHGGSAGGMLMGAVANRS
GELFAGIVAEVPFVDVLNTMLDDTLPLTPPEWPEWGNPIESEKDFRTILSYSPYDNVAAKHYPAILAMAGLTDPRVTYWE
PAKWIARLRATMTSGGPVVLRTNMGAGHGGASGRFNRLDEVAIVYAFALWAVGMADRTA
>Mature_698_residues
TDSSTKAPVAPRRPYSFTRHGITVQDDYAWLKDERWQEVLHDPRLLDADIRAYLEAENGYAESVLGHTAPLQKTIVAEMR
GRIKEDDSSVPSPDGPYAYFRKYREGGQHELFCRTLRHGGAETIGLDGDALARGHDYFKFGGSRHSHDHKLVAWSADTKG
SEYFTIRVRDWDSGDELADVVEETDGGVVWSRDCKSFFYVKLDDNHRPMQVWRHKLGTKQADDVLVYEEKDTGWFTHVHE
STSGRFCVIAGGDHETSEQRLIDLDAPEAPPRLVAARENGVQYSIADRGNELFILTNADGAIDFKIVTAPLAAPERANWR
DFIPHRAGIYVLDHDLYSGHLVRLERANALPSIVIRDLTSGEEHAIAFAEGAYSLDAMGSYEFDTTNLRFAYSSMTTPSE
VWDYDMVTRAKTLRKRQEIPSGHNPADYVTTRIMARAEDGAEVPVSLLHRRDFKADGSAPLLLYGYGSYGHAMPASFSAN
RLSLVDRGFVYAIAHIRGGTDKGWGWYLEGKREKKTNSFDDFAACARALIAANYTSAKRIVGHGGSAGGMLMGAVANRSG
ELFAGIVAEVPFVDVLNTMLDDTLPLTPPEWPEWGNPIESEKDFRTILSYSPYDNVAAKHYPAILAMAGLTDPRVTYWEP
AKWIARLRATMTSGGPVVLRTNMGAGHGGASGRFNRLDEVAIVYAFALWAVGMADRTA

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI284172420, Length=624, Percent_Identity=27.2435897435897, Blast_Score=216, Evalue=5e-56,
Organism=Homo sapiens, GI284172413, Length=624, Percent_Identity=27.2435897435897, Blast_Score=216, Evalue=5e-56,
Organism=Homo sapiens, GI70778815, Length=624, Percent_Identity=27.2435897435897, Blast_Score=216, Evalue=5e-56,
Organism=Homo sapiens, GI284172438, Length=570, Percent_Identity=28.4210526315789, Blast_Score=216, Evalue=8e-56,
Organism=Homo sapiens, GI284172431, Length=570, Percent_Identity=28.4210526315789, Blast_Score=216, Evalue=8e-56,
Organism=Homo sapiens, GI41349456, Length=714, Percent_Identity=25.6302521008403, Blast_Score=202, Evalue=7e-52,
Organism=Homo sapiens, GI108860686, Length=271, Percent_Identity=34.3173431734317, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI108860692, Length=214, Percent_Identity=37.8504672897196, Blast_Score=145, Evalue=2e-34,
Organism=Escherichia coli, GI1788150, Length=686, Percent_Identity=37.9008746355685, Blast_Score=445, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24583414, Length=713, Percent_Identity=25.6661991584853, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI221510989, Length=711, Percent_Identity=24.0506329113924, Blast_Score=180, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 77658; Mature: 77526

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSSTKAPVAPRRPYSFTRHGITVQDDYAWLKDERWQEVLHDPRLLDADIRAYLEAENG
CCCCCCCCCCCCCCCCCHHCCCCEEECCCHHHHHHHHHHHHCCCCEECCHHHEEEECCCC
YAESVLGHTAPLQKTIVAEMRGRIKEDDSSVPSPDGPYAYFRKYREGGQHELFCRTLRHG
HHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCC
GAETIGLDGDALARGHDYFKFGGSRHSHDHKLVAWSADTKGSEYFTIRVRDWDSGDELAD
CCCEECCCCCHHHCCCCCEEECCCCCCCCCEEEEEECCCCCCEEEEEEEEECCCCHHHHH
VVEETDGGVVWSRDCKSFFYVKLDDNHRPMQVWRHKLGTKQADDVLVYEEKDTGWFTHVH
HHHHCCCCEEEECCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEE
ESTSGRFCVIAGGDHETSEQRLIDLDAPEAPPRLVAARENGVQYSIADRGNELFILTNAD
ECCCCCEEEEECCCCCCCCCEEEECCCCCCCCCEEEECCCCCEEEEECCCCEEEEEECCC
GAIDFKIVTAPLAAPERANWRDFIPHRAGIYVLDHDLYSGHLVRLERANALPSIVIRDLT
CEEEEEEEEECCCCCCCCCHHHCCCCCCCEEEEECCCCCCEEEEEECCCCCCHHHEECCC
SGEEHAIAFAEGAYSLDAMGSYEFDTTNLRFAYSSMTTPSEVWDYDMVTRAKTLRKRQEI
CCCCCEEEEECCCCEECCCCCCCCCCCCEEEEEECCCCHHHHHCHHHHHHHHHHHHHHCC
PSGHNPADYVTTRIMARAEDGAEVPVSLLHRRDFKADGSAPLLLYGYGSYGHAMPASFSA
CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCC
NRLSLVDRGFVYAIAHIRGGTDKGWGWYLEGKREKKTNSFDDFAACARALIAANYTSAKR
CEEEHHHCCEEEEEEEECCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHH
IVGHGGSAGGMLMGAVANRSGELFAGIVAEVPFVDVLNTMLDDTLPLTPPEWPEWGNPIE
HHCCCCCCCCEEEEHHHCCCCCEEEHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
SEKDFRTILSYSPYDNVAAKHYPAILAMAGLTDPRVTYWEPAKWIARLRATMTSGGPVVL
CCHHHHHHHCCCCCCCCHHHHCCHHEEEECCCCCCCEEECHHHHHHHHHHHHCCCCCEEE
RTNMGAGHGGASGRFNRLDEVAIVYAFALWAVGMADRTA
EECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDSSTKAPVAPRRPYSFTRHGITVQDDYAWLKDERWQEVLHDPRLLDADIRAYLEAENG
CCCCCCCCCCCCCCCCHHCCCCEEECCCHHHHHHHHHHHHCCCCEECCHHHEEEECCCC
YAESVLGHTAPLQKTIVAEMRGRIKEDDSSVPSPDGPYAYFRKYREGGQHELFCRTLRHG
HHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCC
GAETIGLDGDALARGHDYFKFGGSRHSHDHKLVAWSADTKGSEYFTIRVRDWDSGDELAD
CCCEECCCCCHHHCCCCCEEECCCCCCCCCEEEEEECCCCCCEEEEEEEEECCCCHHHHH
VVEETDGGVVWSRDCKSFFYVKLDDNHRPMQVWRHKLGTKQADDVLVYEEKDTGWFTHVH
HHHHCCCCEEEECCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEE
ESTSGRFCVIAGGDHETSEQRLIDLDAPEAPPRLVAARENGVQYSIADRGNELFILTNAD
ECCCCCEEEEECCCCCCCCCEEEECCCCCCCCCEEEECCCCCEEEEECCCCEEEEEECCC
GAIDFKIVTAPLAAPERANWRDFIPHRAGIYVLDHDLYSGHLVRLERANALPSIVIRDLT
CEEEEEEEEECCCCCCCCCHHHCCCCCCCEEEEECCCCCCEEEEEECCCCCCHHHEECCC
SGEEHAIAFAEGAYSLDAMGSYEFDTTNLRFAYSSMTTPSEVWDYDMVTRAKTLRKRQEI
CCCCCEEEEECCCCEECCCCCCCCCCCCEEEEEECCCCHHHHHCHHHHHHHHHHHHHHCC
PSGHNPADYVTTRIMARAEDGAEVPVSLLHRRDFKADGSAPLLLYGYGSYGHAMPASFSA
CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCC
NRLSLVDRGFVYAIAHIRGGTDKGWGWYLEGKREKKTNSFDDFAACARALIAANYTSAKR
CEEEHHHCCEEEEEEEECCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHH
IVGHGGSAGGMLMGAVANRSGELFAGIVAEVPFVDVLNTMLDDTLPLTPPEWPEWGNPIE
HHCCCCCCCCEEEEHHHCCCCCEEEHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
SEKDFRTILSYSPYDNVAAKHYPAILAMAGLTDPRVTYWEPAKWIARLRATMTSGGPVVL
CCHHHHHHHCCCCCCCCHHHHCCHHEEEECCCCCCCEEECHHHHHHHHHHHHCCCCCEEE
RTNMGAGHGGASGRFNRLDEVAIVYAFALWAVGMADRTA
EECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7629037 [H]