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The map label for this gene is ompR [H]

Identifier: 146343595

GI number: 146343595

Start: 7093255

End: 7094010

Strand: Direct

Name: ompR [H]

Synonym: BRADO6833

Alternate gene names: 146343595

Gene position: 7093255-7094010 (Clockwise)

Preceding gene: 146343594

Following gene: 146343596

Centisome position: 95.13

GC content: 66.67

Gene sequence:

>756_bases
ATGAGTCAGAGCCAGCACATCATCATCGTCGACGATGAGGCACCCGCCCGCGAGATGGTGGGCGATTACCTCAAGATGCA
CGGTTTCACGGTGACCTTGTGCGACGGCGGCAAGAGCCTGCGCAGTGCCATCGAGACTGGCCCGGCCGATCTCGTGGTGC
TTGACCTCAACATGCCCGAAGAGGACGGGCTGTCGATCATCCGCGACCTCAAGGGCCGCACCAACATCCCGGTCATCATG
TTGACGGCGACCGCGAGCCCGATCGATCGCGTCGTCGGGCTCGAGCTCGGCGCGGACGATTACGTCGCCAAGCCCTGCGA
GCTGCGCGAGCTGATGGCCCGCATCCGATCGGTGCTGCGCCGCAGCGCCCCGGCCAAGGTTGCCGCCGCGGCCGTGGCGG
CTGCTCCGGAGCCGGCTCCGGCCAAGGCTCCGGATCCGCAGCTGGTGCGGTTCGGCACCAAATGGCTCGATCTGGACGCT
CAGGCGTTGCGCGACGACGAGGGTAACGAGCATCCCTTGACCGCTTCCGAATTCGGCCTGCTCAAGGTGTTCGCCGCCAA
CCCGAAGCGGGTGCTGTCGCGCGAGCGACTGCTGGAGCTCGCGAACGCCCGGGATGCCGAGGCATTCGACCGGGCAGTGG
ACCTGCGAATCATGCGAATTCGGCGCAAGATCGAGCCGGATCCGACCAAACCAGCCGTGATCCGGACCATTCGCGGCGGC
GGCTACCTGTTCTCGCCGTCCGGCGACAAGGCCTGA

Upstream 100 bases:

>100_bases
AACGCATCGTCGACATGCATGGTGGCGAGGTGACGGCCAAGAGCGATGGGCCGGGATCGGGGTCAACCTTCACCATCACA
CTGCCTGCGGCCGAGTTGTC

Downstream 100 bases:

>100_bases
CGGCGGCCGGCGCGCGAGTAGCGCCTGCAGTCGGCGCGCGCGTTTATTCCATTTTCTGGAACCCAGACTTCCTCATTGTG
GAATAAGGCACATTTCCGCC

Product: two-component system regulator, response regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MSQSQHIIIVDDEAPAREMVGDYLKMHGFTVTLCDGGKSLRSAIETGPADLVVLDLNMPEEDGLSIIRDLKGRTNIPVIM
LTATASPIDRVVGLELGADDYVAKPCELRELMARIRSVLRRSAPAKVAAAAVAAAPEPAPAKAPDPQLVRFGTKWLDLDA
QALRDDEGNEHPLTASEFGLLKVFAANPKRVLSRERLLELANARDAEAFDRAVDLRIMRIRRKIEPDPTKPAVIRTIRGG
GYLFSPSGDKA

Sequences:

>Translated_251_residues
MSQSQHIIIVDDEAPAREMVGDYLKMHGFTVTLCDGGKSLRSAIETGPADLVVLDLNMPEEDGLSIIRDLKGRTNIPVIM
LTATASPIDRVVGLELGADDYVAKPCELRELMARIRSVLRRSAPAKVAAAAVAAAPEPAPAKAPDPQLVRFGTKWLDLDA
QALRDDEGNEHPLTASEFGLLKVFAANPKRVLSRERLLELANARDAEAFDRAVDLRIMRIRRKIEPDPTKPAVIRTIRGG
GYLFSPSGDKA
>Mature_250_residues
SQSQHIIIVDDEAPAREMVGDYLKMHGFTVTLCDGGKSLRSAIETGPADLVVLDLNMPEEDGLSIIRDLKGRTNIPVIML
TATASPIDRVVGLELGADDYVAKPCELRELMARIRSVLRRSAPAKVAAAAVAAAPEPAPAKAPDPQLVRFGTKWLDLDAQ
ALRDDEGNEHPLTASEFGLLKVFAANPKRVLSRERLLELANARDAEAFDRAVDLRIMRIRRKIEPDPTKPAVIRTIRGGG
YLFSPSGDKA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=253, Percent_Identity=40.3162055335968, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1787229, Length=244, Percent_Identity=36.8852459016393, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1790863, Length=242, Percent_Identity=31.404958677686, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1788394, Length=239, Percent_Identity=34.3096234309623, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786599, Length=247, Percent_Identity=36.4372469635627, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI2367329, Length=238, Percent_Identity=34.0336134453782, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1786784, Length=244, Percent_Identity=32.3770491803279, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1786911, Length=239, Percent_Identity=33.0543933054393, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1790860, Length=248, Percent_Identity=32.258064516129, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI145693140, Length=240, Percent_Identity=30.4166666666667, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1787375, Length=242, Percent_Identity=30.5785123966942, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789402, Length=238, Percent_Identity=31.9327731092437, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082012, Length=239, Percent_Identity=30.5439330543933, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790552, Length=244, Percent_Identity=30.327868852459, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1788550, Length=127, Percent_Identity=32.2834645669291, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=142, Percent_Identity=28.8732394366197, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27310; Mature: 27179

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSQHIIIVDDEAPAREMVGDYLKMHGFTVTLCDGGKSLRSAIETGPADLVVLDLNMPE
CCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCEEEEECCCCC
EDGLSIIRDLKGRTNIPVIMLTATASPIDRVVGLELGADDYVAKPCELRELMARIRSVLR
HHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHCEECCCHHHCCCHHHHHHHHHHHHHHH
RSAPAKVAAAAVAAAPEPAPAKAPDPQLVRFGTKWLDLDAQALRDDEGNEHPLTASEFGL
HCCCHHHHHHHHHCCCCCCCCCCCCCHHEECCCHHCCCCHHHHCCCCCCCCCCCHHHCCE
LKVFAANPKRVLSRERLLELANARDAEAFDRAVDLRIMRIRRKIEPDPTKPAVIRTIRGG
EEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCC
GYLFSPSGDKA
CEEECCCCCCC
>Mature Secondary Structure 
SQSQHIIIVDDEAPAREMVGDYLKMHGFTVTLCDGGKSLRSAIETGPADLVVLDLNMPE
CCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCEEEEECCCCC
EDGLSIIRDLKGRTNIPVIMLTATASPIDRVVGLELGADDYVAKPCELRELMARIRSVLR
HHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHCEECCCHHHCCCHHHHHHHHHHHHHHH
RSAPAKVAAAAVAAAPEPAPAKAPDPQLVRFGTKWLDLDAQALRDDEGNEHPLTASEFGL
HCCCHHHHHHHHHCCCCCCCCCCCCCHHEECCCHHCCCCHHHHCCCCCCCCCCCHHHCCE
LKVFAANPKRVLSRERLLELANARDAEAFDRAVDLRIMRIRRKIEPDPTKPAVIRTIRGG
EEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCC
GYLFSPSGDKA
CEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]