Click here to switch to the map view.

The map label for this gene is argD [H]

Identifier: 146343543

GI number: 146343543

Start: 7037398

End: 7038609

Strand: Reverse

Name: argD [H]

Synonym: BRADO6779

Alternate gene names: 146343543

Gene position: 7038609-7037398 (Counterclockwise)

Preceding gene: 146343545

Following gene: 146343542

Centisome position: 94.39

GC content: 65.84

Gene sequence:

>1212_bases
ATGACGAGTGTTGCTGCTACGCATCTTCTCCCCGTATTCGCCCGGGTCGATTTGTCGTTCGAGCGCGGCGAGGGCGCGTG
GCTGATCGCGGCCAATGGTGATCGCTATCTCGACTTCACCTCCGGCGTCGCCGTCAACTCGCTCGGCCATGCGCATCCGC
ATCTCGTCAAGGCGCTGCAGGAGCAGGCGACGAAGCTGTGGCACATGTCGAACCTGTTCAAGAGTCCGGATGGCGAGCGC
CTTGCCGCCAGGCTCTGTGAGCAGAGCTTCGCCGACTACGTGTTCTTCGCCAATTCCGGCGCCGAGGCGATGGAAGGCGC
GATCAAGATCACGCGCAAATATCACGCATCCAAGGGGCATCCCGAGCGTTACCGCATCATCACGTTCGAAGGCGCGTTCC
ACGGCCGCACGCTGGCAACGCTCGCCGCCACCGGTTCCGCGAAATATCTCGACGGCTTCGGCCCGCCGATGGACGGCTTC
GACCAGGTTCCATTCGGCGACATCGAGGCGGTGAAGAAGGCGATCGGTCCGCACACCGCCGGCATCCTGGTCGAGCCGGT
GCAGGGCGAAGGCGGCGTGCGCACCGCGCCGCTCACGTTCTACAAGGCGCTGCGCCAGCTCTGCGACGACAACGGCTTGT
TGCTCGTCATCGACGAGGTGCAGACCGGCATGGGCCGCACCGGCGACCTGTTCGCGCATCGCTGGCTCGGCGTCACGCCT
GACGTCATGTCGCTCGCCAAGGCGCTGGGCGGCGGCTTCCCGATCGGCGCGGTGCTGGCGACGGCCGAGGCGGCCTCGGG
CATGACGCCGGGCTCGCACGGCTCGACCTTCGGTGGCAATCCGCTGGCGGTGTCGGCGGCCAATGCGGTGCTCGACGTGA
TGCTGGCGCCCGGCTTCTTCGATCATGTGCGCAAGATGTCGCTGCTGTTGAAGCAGAAGCTTGCGGCGGTGAAGGATCGT
CATCCTGATATCATCGCGGAAATCCGCGGCGAGGGTCTCTTGATCGGCGTCAAGGCGGTGGTGCCGTCCGGTGATCTGGT
GGCGGCGCTGCGTGACCAGAAGCTGCTGACGGTCGGCGCCGGCGACAATGTGGTGCGCTTCCTGCCGCCTCTGATCGTGA
ACGAGTCCGAAATCGAACAGTCGGTCGAGATGCTCGATCGCGCTTGCACGGCGCTGTCGGGCGGTCCTGCCAGGCAGGCG
GCCGCATCATGA

Upstream 100 bases:

>100_bases
TGAAAAGGCGGCACATTTTGTTTTCCAGGGTGGGGTCCCTGATGCGCGATGACGCCGCATGGCGCGTGTCTCGGCCAGCC
CGTCAACTCATGTGATTGTC

Downstream 100 bases:

>100_bases
GCAAGACTATGGGCAACCCGCCGCGTCACTTCCTCGATCTCACCGAGATGCCGGTCGAGGAGCTGCGCAACATGCTGGCG
CTGTCCAGCCGGATGAAGCA

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT 1 [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MTSVAATHLLPVFARVDLSFERGEGAWLIAANGDRYLDFTSGVAVNSLGHAHPHLVKALQEQATKLWHMSNLFKSPDGER
LAARLCEQSFADYVFFANSGAEAMEGAIKITRKYHASKGHPERYRIITFEGAFHGRTLATLAATGSAKYLDGFGPPMDGF
DQVPFGDIEAVKKAIGPHTAGILVEPVQGEGGVRTAPLTFYKALRQLCDDNGLLLVIDEVQTGMGRTGDLFAHRWLGVTP
DVMSLAKALGGGFPIGAVLATAEAASGMTPGSHGSTFGGNPLAVSAANAVLDVMLAPGFFDHVRKMSLLLKQKLAAVKDR
HPDIIAEIRGEGLLIGVKAVVPSGDLVAALRDQKLLTVGAGDNVVRFLPPLIVNESEIEQSVEMLDRACTALSGGPARQA
AAS

Sequences:

>Translated_403_residues
MTSVAATHLLPVFARVDLSFERGEGAWLIAANGDRYLDFTSGVAVNSLGHAHPHLVKALQEQATKLWHMSNLFKSPDGER
LAARLCEQSFADYVFFANSGAEAMEGAIKITRKYHASKGHPERYRIITFEGAFHGRTLATLAATGSAKYLDGFGPPMDGF
DQVPFGDIEAVKKAIGPHTAGILVEPVQGEGGVRTAPLTFYKALRQLCDDNGLLLVIDEVQTGMGRTGDLFAHRWLGVTP
DVMSLAKALGGGFPIGAVLATAEAASGMTPGSHGSTFGGNPLAVSAANAVLDVMLAPGFFDHVRKMSLLLKQKLAAVKDR
HPDIIAEIRGEGLLIGVKAVVPSGDLVAALRDQKLLTVGAGDNVVRFLPPLIVNESEIEQSVEMLDRACTALSGGPARQA
AAS
>Mature_402_residues
TSVAATHLLPVFARVDLSFERGEGAWLIAANGDRYLDFTSGVAVNSLGHAHPHLVKALQEQATKLWHMSNLFKSPDGERL
AARLCEQSFADYVFFANSGAEAMEGAIKITRKYHASKGHPERYRIITFEGAFHGRTLATLAATGSAKYLDGFGPPMDGFD
QVPFGDIEAVKKAIGPHTAGILVEPVQGEGGVRTAPLTFYKALRQLCDDNGLLLVIDEVQTGMGRTGDLFAHRWLGVTPD
VMSLAKALGGGFPIGAVLATAEAASGMTPGSHGSTFGGNPLAVSAANAVLDVMLAPGFFDHVRKMSLLLKQKLAAVKDRH
PDIIAEIRGEGLLIGVKAVVPSGDLVAALRDQKLLTVGAGDNVVRFLPPLIVNESEIEQSVEMLDRACTALSGGPARQAA
AS

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=390, Percent_Identity=34.1025641025641, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI284507298, Length=298, Percent_Identity=35.5704697986577, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI13994255, Length=451, Percent_Identity=31.0421286031042, Blast_Score=181, Evalue=8e-46,
Organism=Homo sapiens, GI37574042, Length=425, Percent_Identity=26.5882352941176, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI24119277, Length=427, Percent_Identity=28.5714285714286, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI226442705, Length=424, Percent_Identity=25.7075471698113, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI226442709, Length=389, Percent_Identity=26.4781491002571, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI188536080, Length=414, Percent_Identity=25.6038647342995, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI38679950, Length=414, Percent_Identity=25.6038647342995, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI38679946, Length=414, Percent_Identity=25.6038647342995, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1789759, Length=391, Percent_Identity=43.7340153452685, Blast_Score=330, Evalue=8e-92,
Organism=Escherichia coli, GI1788044, Length=388, Percent_Identity=42.5257731958763, Blast_Score=308, Evalue=6e-85,
Organism=Escherichia coli, GI145693181, Length=390, Percent_Identity=35.1282051282051, Blast_Score=231, Evalue=6e-62,
Organism=Escherichia coli, GI1789016, Length=416, Percent_Identity=35.3365384615385, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1787560, Length=402, Percent_Identity=35.0746268656716, Blast_Score=201, Evalue=9e-53,
Organism=Escherichia coli, GI1786991, Length=418, Percent_Identity=30.1435406698565, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786349, Length=314, Percent_Identity=31.8471337579618, Blast_Score=121, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=382, Percent_Identity=34.0314136125654, Blast_Score=225, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI32564660, Length=443, Percent_Identity=29.3453724604966, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI25144274, Length=280, Percent_Identity=35, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=424, Percent_Identity=27.8301886792453, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=445, Percent_Identity=25.6179775280899, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71981843, Length=160, Percent_Identity=30, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324432, Length=394, Percent_Identity=37.5634517766497, Blast_Score=273, Evalue=5e-74,
Organism=Saccharomyces cerevisiae, GI6323470, Length=410, Percent_Identity=34.1463414634146, Blast_Score=213, Evalue=5e-56,
Organism=Saccharomyces cerevisiae, GI6324386, Length=301, Percent_Identity=26.2458471760797, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6321456, Length=428, Percent_Identity=23.5981308411215, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI21357415, Length=391, Percent_Identity=33.2480818414322, Blast_Score=224, Evalue=6e-59,
Organism=Drosophila melanogaster, GI161085790, Length=429, Percent_Identity=30.0699300699301, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI28574759, Length=431, Percent_Identity=29.9303944315545, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI21356575, Length=417, Percent_Identity=27.0983213429257, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI281366494, Length=452, Percent_Identity=26.9911504424779, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24667139, Length=452, Percent_Identity=26.9911504424779, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24667143, Length=452, Percent_Identity=26.9911504424779, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42614; Mature: 42483

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVAATHLLPVFARVDLSFERGEGAWLIAANGDRYLDFTSGVAVNSLGHAHPHLVKALQ
CCCHHHHHHHHHHHHEEEEEECCCCEEEEEECCCEEEEECCCCEECCCCCCCHHHHHHHH
EQATKLWHMSNLFKSPDGERLAARLCEQSFADYVFFANSGAEAMEGAIKITRKYHASKGH
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHCCCCC
PERYRIITFEGAFHGRTLATLAATGSAKYLDGFGPPMDGFDQVPFGDIEAVKKAIGPHTA
CCEEEEEEEECCCCCCEEEEEEECCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
GILVEPVQGEGGVRTAPLTFYKALRQLCDDNGLLLVIDEVQTGMGRTGDLFAHRWLGVTP
CEEEEECCCCCCCEECHHHHHHHHHHHHCCCCEEEEEECHHCCCCCCCHHHHHHHCCCCH
DVMSLAKALGGGFPIGAVLATAEAASGMTPGSHGSTFGGNPLAVSAANAVLDVMLAPGFF
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCHH
DHVRKMSLLLKQKLAAVKDRHPDIIAEIRGEGLLIGVKAVVPSGDLVAALRDQKLLTVGA
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEEEECCCCCEEEEECCCEEEEECC
GDNVVRFLPPLIVNESEIEQSVEMLDRACTALSGGPARQAAAS
CCCHHHHCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCC
>Mature Secondary Structure 
TSVAATHLLPVFARVDLSFERGEGAWLIAANGDRYLDFTSGVAVNSLGHAHPHLVKALQ
CCHHHHHHHHHHHHEEEEEECCCCEEEEEECCCEEEEECCCCEECCCCCCCHHHHHHHH
EQATKLWHMSNLFKSPDGERLAARLCEQSFADYVFFANSGAEAMEGAIKITRKYHASKGH
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHCCCCC
PERYRIITFEGAFHGRTLATLAATGSAKYLDGFGPPMDGFDQVPFGDIEAVKKAIGPHTA
CCEEEEEEEECCCCCCEEEEEEECCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
GILVEPVQGEGGVRTAPLTFYKALRQLCDDNGLLLVIDEVQTGMGRTGDLFAHRWLGVTP
CEEEEECCCCCCCEECHHHHHHHHHHHHCCCCEEEEEECHHCCCCCCCHHHHHHHCCCCH
DVMSLAKALGGGFPIGAVLATAEAASGMTPGSHGSTFGGNPLAVSAANAVLDVMLAPGFF
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCHH
DHVRKMSLLLKQKLAAVKDRHPDIIAEIRGEGLLIGVKAVVPSGDLVAALRDQKLLTVGA
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEEEECCCCCEEEEECCCEEEEECC
GDNVVRFLPPLIVNESEIEQSVEMLDRACTALSGGPARQAAAS
CCCHHHHCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]