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The map label for this gene is argF [H]

Identifier: 146343542

GI number: 146343542

Start: 7036463

End: 7037389

Strand: Reverse

Name: argF [H]

Synonym: BRADO6778

Alternate gene names: 146343542

Gene position: 7037389-7036463 (Counterclockwise)

Preceding gene: 146343543

Following gene: 146343540

Centisome position: 94.38

GC content: 66.34

Gene sequence:

>927_bases
ATGGGCAACCCGCCGCGTCACTTCCTCGATCTCACCGAGATGCCGGTCGAGGAGCTGCGCAACATGCTGGCGCTGTCCAG
CCGGATGAAGCAGACGCTGAAATCCAACGAGCCGTCGAGGAAGCCGCTCGAAGGCAAGGTGCTGGCGATGATCTTCGACA
AGCCGTCGACCCGCACGCGCGTGTCGTTCGATGTCGGCATGCGCCAGCTCGGCGGCGAGGCGATCATGCTGACCGGCACC
GAGATGCAGCTCGGCCGCGGCGAGACCATCGCCGACACCGCGCGCGTACTGTCGCGCTATGTCGATGCGATCATGATCCG
CATCCTCAGCCACGAGGCGCTGCTCGAGCTCGCCGCGCACGCCACCGTGCCGGTCATCAACGGCCTGACGCGGCGCTCGC
ATCCCTGCCAGGTGATGGCCGACGTCATGACCTTCGAGGAGCATCGCGGCTCGATCGAGGGCCGCACCGTGGCCTGGACC
GGCGACGACAACAACGTGCTGGCCTCCTGGGCCCACGCCGCCGAGCGCTTCAAGTTCCGCCTCAACGTCGCCACGCCGCC
GCAGCTCTCGCCCGGCAAGCCGATGAAGGATTTCATCCGCGCCACCCGCGCCGACATTCATCTCGGTCACGACCCAGAGG
GCGCGGTGAAAAACGCCGATTGCGTCATCACCGACACCTGGGTCTCGATGGGCGACAAGGACGGCGAGCACCGCCACAAT
CTGTTGAAGCCCTATCAGGTCAACGCCAAGCTGATGTCCTTGGCGAAGCCCGAGGCCCTCTTCATGCACTGCCTCCCCGC
CCACCGCGGCGAGGAGGTCACCGACGAGGTCATCGACGGCCCGCAGTCCGTCGTCTTCGACGAAGCCGAAAACCGCCTGC
ACGCCCAGAAGGGCATTTTGGCCTGGTGCTTCGGCGAGAGGGCGTAG

Upstream 100 bases:

>100_bases
ACGAGTCCGAAATCGAACAGTCGGTCGAGATGCTCGATCGCGCTTGCACGGCGCTGTCGGGCGGTCCTGCCAGGCAGGCG
GCCGCATCATGAGCAAGACT

Downstream 100 bases:

>100_bases
TCGCCACTAAGGCGCTAGTTGCAAAGGAAGCCCGAAGCCCAGCAATCGGTGCACCCTCTCCCCTTGTGGGAGAGGGTGGT
TTCCATGCGCAGCATGGAAA

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MGNPPRHFLDLTEMPVEELRNMLALSSRMKQTLKSNEPSRKPLEGKVLAMIFDKPSTRTRVSFDVGMRQLGGEAIMLTGT
EMQLGRGETIADTARVLSRYVDAIMIRILSHEALLELAAHATVPVINGLTRRSHPCQVMADVMTFEEHRGSIEGRTVAWT
GDDNNVLASWAHAAERFKFRLNVATPPQLSPGKPMKDFIRATRADIHLGHDPEGAVKNADCVITDTWVSMGDKDGEHRHN
LLKPYQVNAKLMSLAKPEALFMHCLPAHRGEEVTDEVIDGPQSVVFDEAENRLHAQKGILAWCFGERA

Sequences:

>Translated_308_residues
MGNPPRHFLDLTEMPVEELRNMLALSSRMKQTLKSNEPSRKPLEGKVLAMIFDKPSTRTRVSFDVGMRQLGGEAIMLTGT
EMQLGRGETIADTARVLSRYVDAIMIRILSHEALLELAAHATVPVINGLTRRSHPCQVMADVMTFEEHRGSIEGRTVAWT
GDDNNVLASWAHAAERFKFRLNVATPPQLSPGKPMKDFIRATRADIHLGHDPEGAVKNADCVITDTWVSMGDKDGEHRHN
LLKPYQVNAKLMSLAKPEALFMHCLPAHRGEEVTDEVIDGPQSVVFDEAENRLHAQKGILAWCFGERA
>Mature_307_residues
GNPPRHFLDLTEMPVEELRNMLALSSRMKQTLKSNEPSRKPLEGKVLAMIFDKPSTRTRVSFDVGMRQLGGEAIMLTGTE
MQLGRGETIADTARVLSRYVDAIMIRILSHEALLELAAHATVPVINGLTRRSHPCQVMADVMTFEEHRGSIEGRTVAWTG
DDNNVLASWAHAAERFKFRLNVATPPQLSPGKPMKDFIRATRADIHLGHDPEGAVKNADCVITDTWVSMGDKDGEHRHNL
LKPYQVNAKLMSLAKPEALFMHCLPAHRGEEVTDEVIDGPQSVVFDEAENRLHAQKGILAWCFGERA

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=292, Percent_Identity=40.4109589041096, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI18105007, Length=303, Percent_Identity=24.7524752475248, Blast_Score=105, Evalue=4e-23,
Organism=Escherichia coli, GI1790703, Length=323, Percent_Identity=38.390092879257, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1786469, Length=329, Percent_Identity=37.3860182370821, Blast_Score=188, Evalue=3e-49,
Organism=Escherichia coli, GI2367364, Length=315, Percent_Identity=28.2539682539683, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI48994908, Length=343, Percent_Identity=26.2390670553936, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193204318, Length=308, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322373, Length=309, Percent_Identity=33.9805825242718, Blast_Score=189, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6322331, Length=311, Percent_Identity=28.6173633440514, Blast_Score=108, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24642586, Length=310, Percent_Identity=25.1612903225806, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 34304; Mature: 34173

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNPPRHFLDLTEMPVEELRNMLALSSRMKQTLKSNEPSRKPLEGKVLAMIFDKPSTRTR
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEE
VSFDVGMRQLGGEAIMLTGTEMQLGRGETIADTARVLSRYVDAIMIRILSHEALLELAAH
EEHHHHHHHHCCCEEEEECCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATVPVINGLTRRSHPCQVMADVMTFEEHRGSIEGRTVAWTGDDNNVLASWAHAAERFKFR
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHEEEE
LNVATPPQLSPGKPMKDFIRATRADIHLGHDPEGAVKNADCVITDTWVSMGDKDGEHRHN
EECCCCCCCCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEHHHHCCCCCCHHHHH
LLKPYQVNAKLMSLAKPEALFMHCLPAHRGEEVTDEVIDGPQSVVFDEAENRLHAQKGIL
CCCCCCCCHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCEE
AWCFGERA
EEECCCCC
>Mature Secondary Structure 
GNPPRHFLDLTEMPVEELRNMLALSSRMKQTLKSNEPSRKPLEGKVLAMIFDKPSTRTR
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEE
VSFDVGMRQLGGEAIMLTGTEMQLGRGETIADTARVLSRYVDAIMIRILSHEALLELAAH
EEHHHHHHHHCCCEEEEECCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATVPVINGLTRRSHPCQVMADVMTFEEHRGSIEGRTVAWTGDDNNVLASWAHAAERFKFR
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHEEEE
LNVATPPQLSPGKPMKDFIRATRADIHLGHDPEGAVKNADCVITDTWVSMGDKDGEHRHN
EECCCCCCCCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEHHHHCCCCCCHHHHH
LLKPYQVNAKLMSLAKPEALFMHCLPAHRGEEVTDEVIDGPQSVVFDEAENRLHAQKGIL
CCCCCCCCHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCEE
AWCFGERA
EEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA