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The map label for this gene is nuoA [H]

Identifier: 146341115

GI number: 146341115

Start: 4387489

End: 4387854

Strand: Reverse

Name: nuoA [H]

Synonym: BRADO4186

Alternate gene names: 146341115

Gene position: 4387854-4387489 (Counterclockwise)

Preceding gene: 146341119

Following gene: 146341114

Centisome position: 58.85

GC content: 58.47

Gene sequence:

>366_bases
ATGACCGGCATCCTCCAGAACTATCTTCCCCTCGTCGTCTTCATAGGTGTCGCAGCCATCATCGGCGTGGTTCTGCTGAT
CGCGCCCTTCCTGGTCGCCTACCAGCAGCCCGATCCCGAGAAGCTCTCTGCCTACGAATGCGGCTTCAACGCGTTCGATG
ACGCACGCATGAAGTTCGACGTCCGCTTCTACCTGGTTGCTATCCTTTTCATCATCTTCGACCTCGAAGTCGCCTTCCTG
TTCCCCTGGGCAGTCGCATTTGGCAAGCTCGGCGCCGCCGGCTTCTGGTCGATGCTGGTGTTCCTGGCCGTGCTGACGGT
CGGGTTTGCCTACGAATGGAAGAAAGGCGCGCTTGAATGGGATTGA

Upstream 100 bases:

>100_bases
GCTTGTCTTGCGCGGCTTGGTGCGCTGCGCTAAGGCTTCGACCAATTCCAATGCAGCGAGTCTGCGGTTTGCACCGAAAC
CGCAGAGGAAAGTGACGCCG

Downstream 100 bases:

>100_bases
GCCCGACTCCGTCCTCCGGTCCGGTGATCGCACCGGCCCCGAAGGGCATTCTCGATCCCGCGACCGGCAGGCCTGTTGGT
GCCCACGACCCGTATTTCCT

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A 1; NDH-1 subunit A 1; NUO1 1 [H]

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MTGILQNYLPLVVFIGVAAIIGVVLLIAPFLVAYQQPDPEKLSAYECGFNAFDDARMKFDVRFYLVAILFIIFDLEVAFL
FPWAVAFGKLGAAGFWSMLVFLAVLTVGFAYEWKKGALEWD

Sequences:

>Translated_121_residues
MTGILQNYLPLVVFIGVAAIIGVVLLIAPFLVAYQQPDPEKLSAYECGFNAFDDARMKFDVRFYLVAILFIIFDLEVAFL
FPWAVAFGKLGAAGFWSMLVFLAVLTVGFAYEWKKGALEWD
>Mature_120_residues
TGILQNYLPLVVFIGVAAIIGVVLLIAPFLVAYQQPDPEKLSAYECGFNAFDDARMKFDVRFYLVAILFIIFDLEVAFLF
PWAVAFGKLGAAGFWSMLVFLAVLTVGFAYEWKKGALEWD

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=120, Percent_Identity=29.1666666666667, Blast_Score=67, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 13555; Mature: 13424

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGILQNYLPLVVFIGVAAIIGVVLLIAPFLVAYQQPDPEKLSAYECGFNAFDDARMKFD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHHH
VRFYLVAILFIIFDLEVAFLFPWAVAFGKLGAAGFWSMLVFLAVLTVGFAYEWKKGALEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
D
C
>Mature Secondary Structure 
TGILQNYLPLVVFIGVAAIIGVVLLIAPFLVAYQQPDPEKLSAYECGFNAFDDARMKFD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHHH
VRFYLVAILFIIFDLEVAFLFPWAVAFGKLGAAGFWSMLVFLAVLTVGFAYEWKKGALEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]