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The map label for this gene is ubiE [H]

Identifier: 146341119

GI number: 146341119

Start: 4390688

End: 4391545

Strand: Reverse

Name: ubiE [H]

Synonym: BRADO4190

Alternate gene names: 146341119

Gene position: 4391545-4390688 (Counterclockwise)

Preceding gene: 146341120

Following gene: 146341115

Centisome position: 58.89

GC content: 70.51

Gene sequence:

>858_bases
ATGCAACTGCCCGCAGGCCACGACCGCAACGCCGATCAGATCGCCTATTGGAACGGGCCCGGTGGCCAGCGCTGGTCGGA
TCGCCAGGAGGCGCAGGACGTGCTGCTCGCGCCGGTGTCGCAGATCCTGATCGACCGCATCGCGGCCAGGCCGGGCGATC
GCATCCTCGACATCGGCTGCGGCTGTGGCGGCCTGTCGATCGCGCTGGGCGGGCAGGTGGCGCCCAACGGAGCCGTGCTC
GGCGTGGACATCTCGGCGCCGATGCTGGCGCGGGCTCGCGAGATGGCGCCGGCCGGGCTTCCGGTCGAGTTCGTGCTGGC
CGATGCGACCGTGCATCCGTTTCCCAAGGCCAGCTTCGATCTGCTGGTCTCGCGCTTCGGCGTCATGTTCTTCGCCGATC
CCGTGACGTCGTTCGCCAACATGCGCGGCGCGCTGAAGCCGGGGGGCCGTGTCGTGTTCGCCTGCTGGCGCGAGCCCAAG
GCCAATTCCTGGATGATCGCGCCCTTGCAGGCGGTGTATCGCCACGTCCCGAAGCTGCCGGAGATGGGCCCGGAGGATCC
CGGCCCGTTCGCCTTCGCGTCGGAAGCGCGGGTGACGCGCATCCTGACCGGGGCGGGCTTCACCGACGTCGCGCTGGAGG
CTCACGCATTGTCGTTCGACATCGCGCGGGGGCAGGGGCTCGAGGCCGCCGTGCAATCCGCGTTCGAGATCGGTCCCGCC
AGCCGCGCGTTGGAGGGCCATCCCGCCGAGACGCGTGAAGCCGCGCGGCAGTCGGTCCGCGAACTGCTGGCGCAATATCA
GAATGGCGGCAGCGTCACGCTGCCCGGCTCGATCTGGCTGGTGACGGCGCGCGCCTGA

Upstream 100 bases:

>100_bases
TCCGAACGGTGGTGAGCAGGCGTCGTCGCGCCTTCGTGCCTTGACAGGCGCGCCGCGTCCGGGCGCGATGCGGGCCCCGA
TTGAAATGGATCGATCCATC

Downstream 100 bases:

>100_bases
GGCCCGCGCCGGACCGGTGTCAGGAGCGCTCCTCCCAGATCATCGCGAGATGCACGATGGTCTGCACCGCCTTCTCCATG
TCACGGACGCTGACCCATTC

Product: putative S-adenosyl-L-methionine (SAM)-dependent methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MQLPAGHDRNADQIAYWNGPGGQRWSDRQEAQDVLLAPVSQILIDRIAARPGDRILDIGCGCGGLSIALGGQVAPNGAVL
GVDISAPMLARAREMAPAGLPVEFVLADATVHPFPKASFDLLVSRFGVMFFADPVTSFANMRGALKPGGRVVFACWREPK
ANSWMIAPLQAVYRHVPKLPEMGPEDPGPFAFASEARVTRILTGAGFTDVALEAHALSFDIARGQGLEAAVQSAFEIGPA
SRALEGHPAETREAARQSVRELLAQYQNGGSVTLPGSIWLVTARA

Sequences:

>Translated_285_residues
MQLPAGHDRNADQIAYWNGPGGQRWSDRQEAQDVLLAPVSQILIDRIAARPGDRILDIGCGCGGLSIALGGQVAPNGAVL
GVDISAPMLARAREMAPAGLPVEFVLADATVHPFPKASFDLLVSRFGVMFFADPVTSFANMRGALKPGGRVVFACWREPK
ANSWMIAPLQAVYRHVPKLPEMGPEDPGPFAFASEARVTRILTGAGFTDVALEAHALSFDIARGQGLEAAVQSAFEIGPA
SRALEGHPAETREAARQSVRELLAQYQNGGSVTLPGSIWLVTARA
>Mature_285_residues
MQLPAGHDRNADQIAYWNGPGGQRWSDRQEAQDVLLAPVSQILIDRIAARPGDRILDIGCGCGGLSIALGGQVAPNGAVL
GVDISAPMLARAREMAPAGLPVEFVLADATVHPFPKASFDLLVSRFGVMFFADPVTSFANMRGALKPGGRVVFACWREPK
ANSWMIAPLQAVYRHVPKLPEMGPEDPGPFAFASEARVTRILTGAGFTDVALEAHALSFDIARGQGLEAAVQSAFEIGPA
SRALEGHPAETREAARQSVRELLAQYQNGGSVTLPGSIWLVTARA

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Escherichia coli, GI48994983, Length=165, Percent_Identity=29.6969696969697, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 30243; Mature: 30243

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLPAGHDRNADQIAYWNGPGGQRWSDRQEAQDVLLAPVSQILIDRIAARPGDRILDIGC
CCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
GCGGLSIALGGQVAPNGAVLGVDISAPMLARAREMAPAGLPVEFVLADATVHPFPKASFD
CCCCEEEEECCEECCCCEEEEEECCCHHHHHHHHCCCCCCCEEEEEECCEECCCCCHHHH
LLVSRFGVMFFADPVTSFANMRGALKPGGRVVFACWREPKANSWMIAPLQAVYRHVPKLP
HHHHHHHHHEEHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCEEEHHHHHHHHHCCCCC
EMGPEDPGPFAFASEARVTRILTGAGFTDVALEAHALSFDIARGQGLEAAVQSAFEIGPA
CCCCCCCCCCEECCCCCEEEEEECCCCHHHHHHHHHEEEECCCCCCHHHHHHHHHHCCCC
SRALEGHPAETREAARQSVRELLAQYQNGGSVTLPGSIWLVTARA
HHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCEEEEEEECC
>Mature Secondary Structure
MQLPAGHDRNADQIAYWNGPGGQRWSDRQEAQDVLLAPVSQILIDRIAARPGDRILDIGC
CCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
GCGGLSIALGGQVAPNGAVLGVDISAPMLARAREMAPAGLPVEFVLADATVHPFPKASFD
CCCCEEEEECCEECCCCEEEEEECCCHHHHHHHHCCCCCCCEEEEEECCEECCCCCHHHH
LLVSRFGVMFFADPVTSFANMRGALKPGGRVVFACWREPKANSWMIAPLQAVYRHVPKLP
HHHHHHHHHEEHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCEEEHHHHHHHHHCCCCC
EMGPEDPGPFAFASEARVTRILTGAGFTDVALEAHALSFDIARGQGLEAAVQSAFEIGPA
CCCCCCCCCCEECCCCCEEEEEECCCCHHHHHHHHHEEEECCCCCCHHHHHHHHHHCCCC
SRALEGHPAETREAARQSVRELLAQYQNGGSVTLPGSIWLVTARA
HHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA