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The map label for this gene is nuoG [H]

Identifier: 146341107

GI number: 146341107

Start: 4379774

End: 4381843

Strand: Reverse

Name: nuoG [H]

Synonym: BRADO4178

Alternate gene names: 146341107

Gene position: 4381843-4379774 (Counterclockwise)

Preceding gene: 146341108

Following gene: 146341106

Centisome position: 58.76

GC content: 67.2

Gene sequence:

>2070_bases
ATGACCAAGATCATCATCGATGGCAAAGAGATCGATGTGCCGCCGGAGTACACGCTGCTGCAGGCGTGCGAGGCGGCGGG
CGCCGAGATTCCGCGCTTCTGCTATCACGAGCGGCTGTCGATCGCCGGCAACTGCCGGATGTGCCTCGTCGAGGTGAAGG
GCGGACCGAAGCCGGTCGCGAGCTGCGCCTGGGGCGTGCGCGACTGCCGGCCGGGCCCGAAGGGCGAGCCGCCGGAGATC
TCGACCCGGTCGCCGATGGTCAAGAAGGCACGCGAAGGCGTGATGGAATTCCTTCTGATCAACCATCCGCTGGACTGCCC
GATCTGCGACCAGGGCGGCGAGTGCGACCTGCAGGACCAGGCGATGGGCTATGGTGTCGACACCAGCCGCTACGCCGAGA
ACAAGCGCGCCGTCGAGGACAAATATCTCGGCGCGCTGGTCAAGACCTCGATGACCCGCTGCATCCAGTGCACGCGTTGC
GTCCGCTTCTCCGCGGAAGTGTGCGGCGTGCCGGAAATGGGCGCGACCGGTCGCGGCGAGGACATGGAGATCACGACCTA
TCTCGAGCAGGCGCTGAGCTCGGAGCTGCAGGGCAATCTGGTCGACATCTGCCCGGTCGGCGCGCTGACCTCAAAACCCT
ATGCGTTCTCGGCCCGTCCCTGGGAGCTCGGCAAGACGCAGTCGATCGACGTCATGGATGGCTTGGGCTCTGCGATCCGG
GTCGACACCCGCGGCCGCGAGGTGATGCGCATCCTGCCGCGCATCAATGACGCCGTGAACGAGGAGTGGATCTCCGACAA
GACCCGCCATGTCGTCGACGGCCTGCGCACGCAGCGGCTCGATCGCCCCTACGTCCGCGAGGACGGCAAGCTGCGCCCGG
CGTCCTGGCCCGAGGCGTTCAAGGCGATCGCCGCAAAACTGTCGCGCATCGACGGCAAGCGCGTCGGCGCGATCGCCGGC
GATCTTGCCGCCGTCGAGGAGATGTTCGCGCTCAAGGATCTGCTCGCCAAGCTCGGCTCGACCAACGTCGCGGTGCAGGG
TGGCGACAGCTTCGATGCCAGGCTCGGCCGCGCGTCCTATCTGTTCAATCCGACCATCGCCGGCATCGAGCAGGCCGACG
CGATCCTGATCATCGGCGCCAATCCGCGCAAGGAAGCCGCGGTGCTGAACGCCCGCATCCGCAAGCGCTGGCGTTCGGGC
CAGCTCAAGGTCGGTCTGGTCGGTCCGAAGGTCGATCTCACTTATGCCTATGAGCACATCGGCGCCGGCACGGACTCGCT
GAGCGACGTCGCTGCCGGCAAGCATTCCTTCGCGACCGCATTCCGCAACGCCAAGAACCCGATCGTGCTGGTCGGCGCCG
GTGCGGCCGGCCGTCATGACGGCGGCGCAATCCTGGCGCTCGCCGCCAAGATCGCGATGGACGTCAACGCGGTGCGTGAC
GACTGGAACGGTTTTGCCGTGCTGCACGACACCGCCTCGCGGGTCGGCGCGCTCGACATCGGCTTCAACGGCACCGGGCT
CACTGGCGCCCAGATGACCACCTTCGGCACCATGGACGTGATGTTCCTGCTCGGCGCCGACGAGGTCGAGGTGCCCGAAG
GCGTGTTCACCGTCTACATCGGCACCCATGGCGACCGCGGCGCGCATCGCGCCGACGTCATCCTGCCCGGGGCGGCCTAC
ACCGAGAAGTCCGGCCTCTACGTCAACACCGAGGGACGGGTGCAGATCGCGGCGCGGGCGTCGTTCCCGCCGGGCGAGGC
GCGCGAGGACTGGGCGATCATCCGTGCACTGTCCGATGTGCTCGGCCGCAAGCTCGGCTACGACTCGCTGGCATCGCTGC
GCGCCGAGATCGTCAAGGCGGTGCCGCATCTCGGCCGCATCGACCAGATCGAGGCCGGCACAATCGCCGACATCAAGACC
CTGGCAGGCAAGGGCGGCAGCCTCGAAAAGGCGCCGTTCAAGCCTCTGATCGATGACTTCTATCTCACCAATCCGATCGC
GCGCGCATCGGCGGTCATGGCGGAATGCTCCCGCTTGGCCTCCGGGCAGATGCTGACGGCAGCGGAGTGA

Upstream 100 bases:

>100_bases
TAGGTGGTGGCGGTCCTGTCCGCCAGCGAGGTTTTCCTCCGCGCTTGCGCCCTCACGGCGCGCAGCGCGGTGGTCCGTGG
TTTGAGAGAGATGTGAGGCA

Downstream 100 bases:

>100_bases
GCGTGACCTGATGGCTGATTTCTTCGCAAGCTCGTTCTGGACCGGCTTCCTCTGGCCGCTGATCATCATGATCGCGCAGA
GCGTGCTGCTCCTCGTCGTC

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I, chain 3; NDH-1, chain 3 [H]

Number of amino acids: Translated: 689; Mature: 688

Protein sequence:

>689_residues
MTKIIIDGKEIDVPPEYTLLQACEAAGAEIPRFCYHERLSIAGNCRMCLVEVKGGPKPVASCAWGVRDCRPGPKGEPPEI
STRSPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMGYGVDTSRYAENKRAVEDKYLGALVKTSMTRCIQCTRC
VRFSAEVCGVPEMGATGRGEDMEITTYLEQALSSELQGNLVDICPVGALTSKPYAFSARPWELGKTQSIDVMDGLGSAIR
VDTRGREVMRILPRINDAVNEEWISDKTRHVVDGLRTQRLDRPYVREDGKLRPASWPEAFKAIAAKLSRIDGKRVGAIAG
DLAAVEEMFALKDLLAKLGSTNVAVQGGDSFDARLGRASYLFNPTIAGIEQADAILIIGANPRKEAAVLNARIRKRWRSG
QLKVGLVGPKVDLTYAYEHIGAGTDSLSDVAAGKHSFATAFRNAKNPIVLVGAGAAGRHDGGAILALAAKIAMDVNAVRD
DWNGFAVLHDTASRVGALDIGFNGTGLTGAQMTTFGTMDVMFLLGADEVEVPEGVFTVYIGTHGDRGAHRADVILPGAAY
TEKSGLYVNTEGRVQIAARASFPPGEAREDWAIIRALSDVLGRKLGYDSLASLRAEIVKAVPHLGRIDQIEAGTIADIKT
LAGKGGSLEKAPFKPLIDDFYLTNPIARASAVMAECSRLASGQMLTAAE

Sequences:

>Translated_689_residues
MTKIIIDGKEIDVPPEYTLLQACEAAGAEIPRFCYHERLSIAGNCRMCLVEVKGGPKPVASCAWGVRDCRPGPKGEPPEI
STRSPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMGYGVDTSRYAENKRAVEDKYLGALVKTSMTRCIQCTRC
VRFSAEVCGVPEMGATGRGEDMEITTYLEQALSSELQGNLVDICPVGALTSKPYAFSARPWELGKTQSIDVMDGLGSAIR
VDTRGREVMRILPRINDAVNEEWISDKTRHVVDGLRTQRLDRPYVREDGKLRPASWPEAFKAIAAKLSRIDGKRVGAIAG
DLAAVEEMFALKDLLAKLGSTNVAVQGGDSFDARLGRASYLFNPTIAGIEQADAILIIGANPRKEAAVLNARIRKRWRSG
QLKVGLVGPKVDLTYAYEHIGAGTDSLSDVAAGKHSFATAFRNAKNPIVLVGAGAAGRHDGGAILALAAKIAMDVNAVRD
DWNGFAVLHDTASRVGALDIGFNGTGLTGAQMTTFGTMDVMFLLGADEVEVPEGVFTVYIGTHGDRGAHRADVILPGAAY
TEKSGLYVNTEGRVQIAARASFPPGEAREDWAIIRALSDVLGRKLGYDSLASLRAEIVKAVPHLGRIDQIEAGTIADIKT
LAGKGGSLEKAPFKPLIDDFYLTNPIARASAVMAECSRLASGQMLTAAE
>Mature_688_residues
TKIIIDGKEIDVPPEYTLLQACEAAGAEIPRFCYHERLSIAGNCRMCLVEVKGGPKPVASCAWGVRDCRPGPKGEPPEIS
TRSPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMGYGVDTSRYAENKRAVEDKYLGALVKTSMTRCIQCTRCV
RFSAEVCGVPEMGATGRGEDMEITTYLEQALSSELQGNLVDICPVGALTSKPYAFSARPWELGKTQSIDVMDGLGSAIRV
DTRGREVMRILPRINDAVNEEWISDKTRHVVDGLRTQRLDRPYVREDGKLRPASWPEAFKAIAAKLSRIDGKRVGAIAGD
LAAVEEMFALKDLLAKLGSTNVAVQGGDSFDARLGRASYLFNPTIAGIEQADAILIIGANPRKEAAVLNARIRKRWRSGQ
LKVGLVGPKVDLTYAYEHIGAGTDSLSDVAAGKHSFATAFRNAKNPIVLVGAGAAGRHDGGAILALAAKIAMDVNAVRDD
WNGFAVLHDTASRVGALDIGFNGTGLTGAQMTTFGTMDVMFLLGADEVEVPEGVFTVYIGTHGDRGAHRADVILPGAAYT
EKSGLYVNTEGRVQIAARASFPPGEAREDWAIIRALSDVLGRKLGYDSLASLRAEIVKAVPHLGRIDQIEAGTIADIKTL
AGKGGSLEKAPFKPLIDDFYLTNPIARASAVMAECSRLASGQMLTAAE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=697, Percent_Identity=52.2238163558106, Blast_Score=698, Evalue=0.0,
Organism=Escherichia coli, GI145693161, Length=405, Percent_Identity=30.1234567901235, Blast_Score=181, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17565758, Length=698, Percent_Identity=48.7106017191977, Blast_Score=639, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32566231, Length=590, Percent_Identity=51.0169491525424, Blast_Score=578, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI193209088, Length=260, Percent_Identity=61.5384615384615, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI24640559, Length=691, Percent_Identity=49.9276410998553, Blast_Score=661, Evalue=0.0,
Organism=Drosophila melanogaster, GI24640557, Length=691, Percent_Identity=49.9276410998553, Blast_Score=661, Evalue=0.0,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 73904; Mature: 73773

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIIIDGKEIDVPPEYTLLQACEAAGAEIPRFCYHERLSIAGNCRMCLVEVKGGPKPVA
CCEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHH
SCAWGVRDCRPGPKGEPPEISTRSPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQ
HHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
AMGYGVDTSRYAENKRAVEDKYLGALVKTSMTRCIQCTRCVRFSAEVCGVPEMGATGRGE
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DMEITTYLEQALSSELQGNLVDICPVGALTSKPYAFSARPWELGKTQSIDVMDGLGSAIR
CCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEECCCCCCCCCCCCCHHHHCCCCEEE
VDTRGREVMRILPRINDAVNEEWISDKTRHVVDGLRTQRLDRPYVREDGKLRPASWPEAF
ECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
KAIAAKLSRIDGKRVGAIAGDLAAVEEMFALKDLLAKLGSTNVAVQGGDSFDARLGRASY
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHCCCCEE
LFNPTIAGIEQADAILIIGANPRKEAAVLNARIRKRWRSGQLKVGLVGPKVDLTYAYEHI
EECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEHHHHH
GAGTDSLSDVAAGKHSFATAFRNAKNPIVLVGAGAAGRHDGGAILALAAKIAMDVNAVRD
CCCCCCHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHC
DWNGFAVLHDTASRVGALDIGFNGTGLTGAQMTTFGTMDVMFLLGADEVEVPEGVFTVYI
CCCCEEEEEECHHHCEEEEECCCCCCCCCCCEEECCHHEEEEEECCCCCCCCCCEEEEEE
GTHGDRGAHRADVILPGAAYTEKSGLYVNTEGRVQIAARASFPPGEAREDWAIIRALSDV
ECCCCCCCCCCCEEECCCCEECCCCEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
LGRKLGYDSLASLRAEIVKAVPHLGRIDQIEAGTIADIKTLAGKGGSLEKAPFKPLIDDF
HHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHH
YLTNPIARASAVMAECSRLASGQMLTAAE
HHCCHHHHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure 
TKIIIDGKEIDVPPEYTLLQACEAAGAEIPRFCYHERLSIAGNCRMCLVEVKGGPKPVA
CEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHH
SCAWGVRDCRPGPKGEPPEISTRSPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQ
HHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
AMGYGVDTSRYAENKRAVEDKYLGALVKTSMTRCIQCTRCVRFSAEVCGVPEMGATGRGE
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DMEITTYLEQALSSELQGNLVDICPVGALTSKPYAFSARPWELGKTQSIDVMDGLGSAIR
CCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEECCCCCCCCCCCCCHHHHCCCCEEE
VDTRGREVMRILPRINDAVNEEWISDKTRHVVDGLRTQRLDRPYVREDGKLRPASWPEAF
ECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
KAIAAKLSRIDGKRVGAIAGDLAAVEEMFALKDLLAKLGSTNVAVQGGDSFDARLGRASY
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHCCCCEE
LFNPTIAGIEQADAILIIGANPRKEAAVLNARIRKRWRSGQLKVGLVGPKVDLTYAYEHI
EECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEHHHHH
GAGTDSLSDVAAGKHSFATAFRNAKNPIVLVGAGAAGRHDGGAILALAAKIAMDVNAVRD
CCCCCCHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHC
DWNGFAVLHDTASRVGALDIGFNGTGLTGAQMTTFGTMDVMFLLGADEVEVPEGVFTVYI
CCCCEEEEEECHHHCEEEEECCCCCCCCCCCEEECCHHEEEEEECCCCCCCCCCEEEEEE
GTHGDRGAHRADVILPGAAYTEKSGLYVNTEGRVQIAARASFPPGEAREDWAIIRALSDV
ECCCCCCCCCCCEEECCCCEECCCCEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
LGRKLGYDSLASLRAEIVKAVPHLGRIDQIEAGTIADIKTLAGKGGSLEKAPFKPLIDDF
HHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHH
YLTNPIARASAVMAECSRLASGQMLTAAE
HHCCHHHHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1605643; 8422400 [H]