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The map label for this gene is nuoH [H]

Identifier: 146341106

GI number: 146341106

Start: 4378693

End: 4379763

Strand: Reverse

Name: nuoH [H]

Synonym: BRADO4177

Alternate gene names: 146341106

Gene position: 4379763-4378693 (Counterclockwise)

Preceding gene: 146341107

Following gene: 146341105

Centisome position: 58.74

GC content: 63.03

Gene sequence:

>1071_bases
ATGGCTGATTTCTTCGCAAGCTCGTTCTGGACCGGCTTCCTCTGGCCGCTGATCATCATGATCGCGCAGAGCGTGCTGCT
CCTCGTCGTCCTCCTGATCGCGATCGCCTACATCCTGCTCGCCGACCGCAAGATCTGGGCGGCGGTGCAGATCCGCAGAG
GCCCTAACGTGGTCGGGCCGTTCGGCCTATTCCAGTCGTTCGCCGACCTCCTGAAGTTCGTACTCAAGGAGCCGATCATT
CCGGCCGGCGCCAACAAGGGCGTGTTCCTGTTGGCTCCGCTGGTGTCGTGCGTGCTCGCGCTGGCGGCTTGGGCTGTCAT
CCCGACGAATCTCGGCTGGGCGATCGCCGACATCAATGTCGGCATCCTCTTCATCTTCGCGATCTCGTCGCTGTCGATCT
ACGGCATCATCATGGCCGGCTGGTCGTCGAACTCGAAGTATCCGTTCCTGGCGGCGCTACGCTCGGCGGCCCAGATGGTG
TCCTACGAGGTCTCGATCGGCTTCGTGATCATCACCGTGTTGCTCTGCGCCGGCACCCTGAACCTCTCGGCTGTCGTCGA
GGCGCAGCATGCGCGCGGCCTCGCCAGCCTGATCGGCCTGCCGCAGCTGACGATCCTGAACTGGTATGTCTGGCCGCTGT
TCCCGATGTTCGTGGTGTTCTACGTCTCGGCGCTCGCCGAGACCAACCGCCCGCCGTTCGATCTGGTTGAGGCGGAATCG
GAGCTCGTCGCCGGCTTCATGGTCGAGTACGGCTCCACGCCGTATCTCCTGTTCATGCTCGGCGAATATGTCGCGATCAC
CACGATGTGCGCGCTGGCGACGATCCTGTTCTTGGGGGGCTGGCTGCCGCCGATCGACGTGGCGCCGTTTAACTGGGTGC
CGGGCGTGATCTGGTTCGCGCTCAAGCTGTTCTTCATGTTCTTCCTGATCGCGATGGCGAAAGCGATCGTGCCGCGCTAC
CGCTATGACCAGTTGATGCGACTCGGCTGGAAGGTGTTCCTGCCGCTGTCGCTGGTCATGGTGGTCGTTGTCGCGGGCGT
GCTGCACTTCGCCGGCATCGCGCCGAAATGA

Upstream 100 bases:

>100_bases
TATCTCACCAATCCGATCGCGCGCGCATCGGCGGTCATGGCGGAATGCTCCCGCTTGGCCTCCGGGCAGATGCTGACGGC
AGCGGAGTGAGCGTGACCTG

Downstream 100 bases:

>100_bases
GGCTGTCATGAACATTTCCGCCACTGCACGGTCGCTGCTGCTGCAGGAGTTCGTCTCCGCGTTCTTCCTCGCGATGCGCT
ACTTCTTCAAGCCCAAGCCG

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MADFFASSFWTGFLWPLIIMIAQSVLLLVVLLIAIAYILLADRKIWAAVQIRRGPNVVGPFGLFQSFADLLKFVLKEPII
PAGANKGVFLLAPLVSCVLALAAWAVIPTNLGWAIADINVGILFIFAISSLSIYGIIMAGWSSNSKYPFLAALRSAAQMV
SYEVSIGFVIITVLLCAGTLNLSAVVEAQHARGLASLIGLPQLTILNWYVWPLFPMFVVFYVSALAETNRPPFDLVEAES
ELVAGFMVEYGSTPYLLFMLGEYVAITTMCALATILFLGGWLPPIDVAPFNWVPGVIWFALKLFFMFFLIAMAKAIVPRY
RYDQLMRLGWKVFLPLSLVMVVVVAGVLHFAGIAPK

Sequences:

>Translated_356_residues
MADFFASSFWTGFLWPLIIMIAQSVLLLVVLLIAIAYILLADRKIWAAVQIRRGPNVVGPFGLFQSFADLLKFVLKEPII
PAGANKGVFLLAPLVSCVLALAAWAVIPTNLGWAIADINVGILFIFAISSLSIYGIIMAGWSSNSKYPFLAALRSAAQMV
SYEVSIGFVIITVLLCAGTLNLSAVVEAQHARGLASLIGLPQLTILNWYVWPLFPMFVVFYVSALAETNRPPFDLVEAES
ELVAGFMVEYGSTPYLLFMLGEYVAITTMCALATILFLGGWLPPIDVAPFNWVPGVIWFALKLFFMFFLIAMAKAIVPRY
RYDQLMRLGWKVFLPLSLVMVVVVAGVLHFAGIAPK
>Mature_355_residues
ADFFASSFWTGFLWPLIIMIAQSVLLLVVLLIAIAYILLADRKIWAAVQIRRGPNVVGPFGLFQSFADLLKFVLKEPIIP
AGANKGVFLLAPLVSCVLALAAWAVIPTNLGWAIADINVGILFIFAISSLSIYGIIMAGWSSNSKYPFLAALRSAAQMVS
YEVSIGFVIITVLLCAGTLNLSAVVEAQHARGLASLIGLPQLTILNWYVWPLFPMFVVFYVSALAETNRPPFDLVEAESE
LVAGFMVEYGSTPYLLFMLGEYVAITTMCALATILFLGGWLPPIDVAPFNWVPGVIWFALKLFFMFFLIAMAKAIVPRYR
YDQLMRLGWKVFLPLSLVMVVVVAGVLHFAGIAPK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=324, Percent_Identity=37.6543209876543, Blast_Score=224, Evalue=9e-59,
Organism=Escherichia coli, GI1788618, Length=333, Percent_Identity=37.8378378378378, Blast_Score=236, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 39070; Mature: 38938

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFFASSFWTGFLWPLIIMIAQSVLLLVVLLIAIAYILLADRKIWAAVQIRRGPNVVGP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEECCCCCCCH
FGLFQSFADLLKFVLKEPIIPAGANKGVFLLAPLVSCVLALAAWAVIPTNLGWAIADINV
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHH
GILFIFAISSLSIYGIIMAGWSSNSKYPFLAALRSAAQMVSYEVSIGFVIITVLLCAGTL
HHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NLSAVVEAQHARGLASLIGLPQLTILNWYVWPLFPMFVVFYVSALAETNRPPFDLVEAES
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ELVAGFMVEYGSTPYLLFMLGEYVAITTMCALATILFLGGWLPPIDVAPFNWVPGVIWFA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
LKLFFMFFLIAMAKAIVPRYRYDQLMRLGWKVFLPLSLVMVVVVAGVLHFAGIAPK
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ADFFASSFWTGFLWPLIIMIAQSVLLLVVLLIAIAYILLADRKIWAAVQIRRGPNVVGP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEECCCCCCCH
FGLFQSFADLLKFVLKEPIIPAGANKGVFLLAPLVSCVLALAAWAVIPTNLGWAIADINV
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHH
GILFIFAISSLSIYGIIMAGWSSNSKYPFLAALRSAAQMVSYEVSIGFVIITVLLCAGTL
HHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NLSAVVEAQHARGLASLIGLPQLTILNWYVWPLFPMFVVFYVSALAETNRPPFDLVEAES
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ELVAGFMVEYGSTPYLLFMLGEYVAITTMCALATILFLGGWLPPIDVAPFNWVPGVIWFA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
LKLFFMFFLIAMAKAIVPRYRYDQLMRLGWKVFLPLSLVMVVVVAGVLHFAGIAPK
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA