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The map label for this gene is glnS [H]

Identifier: 146341053

GI number: 146341053

Start: 4316864

End: 4318555

Strand: Reverse

Name: glnS [H]

Synonym: BRADO4124

Alternate gene names: 146341053

Gene position: 4318555-4316864 (Counterclockwise)

Preceding gene: 146341056

Following gene: 146341051

Centisome position: 57.92

GC content: 64.18

Gene sequence:

>1692_bases
TTGATGACCACGACGACAGACACGGCAGCGACGGCAGAGGCAGGGCGCGACTTCATCCGCGACATCGTCCAGGCCGATCT
CGACAGCGGCAGGCACAAGACCGTCGTCACCCGGTTCCCGCCGGAGCCGAACGGCTACCTGCATATCGGCCATGCCAAGT
CGATCGGTCTCAACTTCGGCATCGCCCGGGAGTTCGGCGGCCGCTGCAATCTGCGCTTCGACGACACCAATCCGACCAAG
GAAGAGCAGGAATATATCGATTCCATCCAGGCCGACGTGCGCTGGCTCGGCTACGACTGGGGCGACAATCTGTTCTACGC
CTCGGATTATTTCGAGCGGCTTTACGACTGGGCCGAGGGCCTGATCAAGGCCGGCCTCGCTTATGTCGACGACCAGACCC
AGGAGGAGATCCGGGCGTCGCGCGGCACCTTGACCGAGCCAGGCAAGAACAGCCCGTTCCGCGATCGTTCGGTCGAGGAG
AATCTCGACCTGTTCCGGCGCATGAAGGCCGGTGAATTCCCGAACGGCGCGCGCGTGCTGCGCGCCAAGATCGACATGGC
GGCCGGCAACATCAATCTGCGCGACCCCGTGCTGTACCGGATCCTGCACGCGCACCATCCGCGCACCGGCGACACCTGGA
AGATCTATCCGAGCTACGACTATGCACACGGTCAGTCGGACGCGATCGAGGGCGTGACGCATTCGATCTGCACGCTCGAA
TTCGAGGATCACCGGCCGCTGTACGAATGGCTGCTCGACAAGCTGCCGGTGCCGTCGCATCCGCGCCAGTACGAGTTCGC
GCGCCTCAACCTGACCTACACGCTGCTGTCGAAGCGCGTGCTGACGCGGCTGGTGCAGGACGGGCATGTCTCCGGCTGGG
ACGATCCGCGCATGCCGACCATTGCCGGGCTGAAGCGGCGTGGCGTGCCGCCGGCGGCGGTGCGCGAATTCACCAAGCGC
ATCGGCATTGCAAAAGCCAACAGCGTCGTCGACGTCGGCATGCTGGAATTCTGCATCCGCGAGGAGCTCAACCGAACGGC
GCAGCGCCGCATGGCGGTGCTGCGTCCCTTGAAGGTCTTGATCGAGAACTATCCGGAAGGCCAGGTCGAGGAGCTCGAGG
CGATCAATCATCCCGATGATCCCTCCGCCGGCACGCGCAAGATCGCCTTCGGCCGCGAGCTCTATATCGAGCAGGATGAC
TTCATGGAGAACCCGCCGAAGAAGTTCTTCCGCCTGTCGCCCGGCAATGAGGTGCGCCTGCGCTACGCGTATTTCATCAA
GTGCCGCGAGGTCATCAAGAACGATGCCGGCGAGATCGTCGAGCTGCGCTGCACCTATGATCCCGAGACCAAGGGCGGCA
ACGCGCCGGACGGACGCAAGGTCAAGGCGACGATGCACTGGCTGCCGGCCGCGCAGTCGCTGACTGCCGAGATCCGCCTC
TACAACCAGCTGTTCGCCAATCCAAGCCCGAACGCGGCCGATTTCACCGCCGACCTCAATCCGGACTCGCTGGAGGTGCT
GGCCGACGCGCGCATCGAGCCTTCGATCGCCGCCAGCAATTCGGATGCGCCTGTTCAGTTCGAGCGCCAGGGCTACTTCG
TGCGCGATCCGGACTCGACGCCCGACAGGCTGGTGTTCAACCGCACCATCGGCCTGCGCGACACCTTCGCGAAGGAGGTC
GCGAAAGGGTAG

Upstream 100 bases:

>100_bases
AAGGGCGGGGGGTGTATAGCAGGCCTATTGCATAACTAAAGCCTTCCTTGGGGGAGGCGGATTTGGCAGATAGGCTGGAA
GATTCCGGAGCAGGACATTC

Downstream 100 bases:

>100_bases
TCCGGCGGATCCGGCCTCAGCCGATCGCGTCCTGTCCGGCATCCGTAAGCGTCGGCACGCCGTCGCTGAGCGCGACGAGG
CCGCGCTCGGTCAGCAGCGC

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MMTTTTDTAATAEAGRDFIRDIVQADLDSGRHKTVVTRFPPEPNGYLHIGHAKSIGLNFGIAREFGGRCNLRFDDTNPTK
EEQEYIDSIQADVRWLGYDWGDNLFYASDYFERLYDWAEGLIKAGLAYVDDQTQEEIRASRGTLTEPGKNSPFRDRSVEE
NLDLFRRMKAGEFPNGARVLRAKIDMAAGNINLRDPVLYRILHAHHPRTGDTWKIYPSYDYAHGQSDAIEGVTHSICTLE
FEDHRPLYEWLLDKLPVPSHPRQYEFARLNLTYTLLSKRVLTRLVQDGHVSGWDDPRMPTIAGLKRRGVPPAAVREFTKR
IGIAKANSVVDVGMLEFCIREELNRTAQRRMAVLRPLKVLIENYPEGQVEELEAINHPDDPSAGTRKIAFGRELYIEQDD
FMENPPKKFFRLSPGNEVRLRYAYFIKCREVIKNDAGEIVELRCTYDPETKGGNAPDGRKVKATMHWLPAAQSLTAEIRL
YNQLFANPSPNAADFTADLNPDSLEVLADARIEPSIAASNSDAPVQFERQGYFVRDPDSTPDRLVFNRTIGLRDTFAKEV
AKG

Sequences:

>Translated_563_residues
MMTTTTDTAATAEAGRDFIRDIVQADLDSGRHKTVVTRFPPEPNGYLHIGHAKSIGLNFGIAREFGGRCNLRFDDTNPTK
EEQEYIDSIQADVRWLGYDWGDNLFYASDYFERLYDWAEGLIKAGLAYVDDQTQEEIRASRGTLTEPGKNSPFRDRSVEE
NLDLFRRMKAGEFPNGARVLRAKIDMAAGNINLRDPVLYRILHAHHPRTGDTWKIYPSYDYAHGQSDAIEGVTHSICTLE
FEDHRPLYEWLLDKLPVPSHPRQYEFARLNLTYTLLSKRVLTRLVQDGHVSGWDDPRMPTIAGLKRRGVPPAAVREFTKR
IGIAKANSVVDVGMLEFCIREELNRTAQRRMAVLRPLKVLIENYPEGQVEELEAINHPDDPSAGTRKIAFGRELYIEQDD
FMENPPKKFFRLSPGNEVRLRYAYFIKCREVIKNDAGEIVELRCTYDPETKGGNAPDGRKVKATMHWLPAAQSLTAEIRL
YNQLFANPSPNAADFTADLNPDSLEVLADARIEPSIAASNSDAPVQFERQGYFVRDPDSTPDRLVFNRTIGLRDTFAKEV
AKG
>Mature_563_residues
MMTTTTDTAATAEAGRDFIRDIVQADLDSGRHKTVVTRFPPEPNGYLHIGHAKSIGLNFGIAREFGGRCNLRFDDTNPTK
EEQEYIDSIQADVRWLGYDWGDNLFYASDYFERLYDWAEGLIKAGLAYVDDQTQEEIRASRGTLTEPGKNSPFRDRSVEE
NLDLFRRMKAGEFPNGARVLRAKIDMAAGNINLRDPVLYRILHAHHPRTGDTWKIYPSYDYAHGQSDAIEGVTHSICTLE
FEDHRPLYEWLLDKLPVPSHPRQYEFARLNLTYTLLSKRVLTRLVQDGHVSGWDDPRMPTIAGLKRRGVPPAAVREFTKR
IGIAKANSVVDVGMLEFCIREELNRTAQRRMAVLRPLKVLIENYPEGQVEELEAINHPDDPSAGTRKIAFGRELYIEQDD
FMENPPKKFFRLSPGNEVRLRYAYFIKCREVIKNDAGEIVELRCTYDPETKGGNAPDGRKVKATMHWLPAAQSLTAEIRL
YNQLFANPSPNAADFTADLNPDSLEVLADARIEPSIAASNSDAPVQFERQGYFVRDPDSTPDRLVFNRTIGLRDTFAKEV
AKG

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=526, Percent_Identity=44.8669201520913, Blast_Score=428, Evalue=1e-120,
Organism=Homo sapiens, GI62241042, Length=549, Percent_Identity=32.9690346083789, Blast_Score=266, Evalue=3e-71,
Organism=Escherichia coli, GI1786895, Length=544, Percent_Identity=56.9852941176471, Blast_Score=640, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=123, Percent_Identity=29.2682926829268, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17543332, Length=531, Percent_Identity=42.5612052730697, Blast_Score=415, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17511007, Length=368, Percent_Identity=37.5, Blast_Score=232, Evalue=5e-61,
Organism=Saccharomyces cerevisiae, GI6324742, Length=564, Percent_Identity=39.8936170212766, Blast_Score=399, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6321192, Length=517, Percent_Identity=35.2030947775629, Blast_Score=289, Evalue=7e-79,
Organism=Drosophila melanogaster, GI17864488, Length=532, Percent_Identity=43.0451127819549, Blast_Score=423, Evalue=1e-118,
Organism=Drosophila melanogaster, GI24649466, Length=524, Percent_Identity=33.206106870229, Blast_Score=253, Evalue=2e-67,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 63915; Mature: 63915

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTTTTDTAATAEAGRDFIRDIVQADLDSGRHKTVVTRFPPEPNGYLHIGHAKSIGLNFG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCC
IAREFGGRCNLRFDDTNPTKEEQEYIDSIQADVRWLGYDWGDNLFYASDYFERLYDWAEG
CHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCEEEHHHHHHHHHHHHHH
LIKAGLAYVDDQTQEEIRASRGTLTEPGKNSPFRDRSVEENLDLFRRMKAGEFPNGARVL
HHHCCHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHEE
RAKIDMAAGNINLRDPVLYRILHAHHPRTGDTWKIYPSYDYAHGQSDAIEGVTHSICTLE
EEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHHEEEEEE
FEDHRPLYEWLLDKLPVPSHPRQYEFARLNLTYTLLSKRVLTRLVQDGHVSGWDDPRMPT
ECCCCCHHHHHHHHCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
IAGLKRRGVPPAAVREFTKRIGIAKANSVVDVGMLEFCIREELNRTAQRRMAVLRPLKVL
HHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IENYPEGQVEELEAINHPDDPSAGTRKIAFGRELYIEQDDFMENPPKKFFRLSPGNEVRL
HHCCCCCHHHHHHHCCCCCCCCCCCEEEECCCEEEEECHHHCCCCCHHHEECCCCCCEEE
RYAYFIKCREVIKNDAGEIVELRCTYDPETKGGNAPDGRKVKATMHWLPAAQSLTAEIRL
EHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHH
YNQLFANPSPNAADFTADLNPDSLEVLADARIEPSIAASNSDAPVQFERQGYFVRDPDST
HHHHHCCCCCCCCCEEECCCCCHHHHHCCCCCCCCEECCCCCCCEEECCCCCEEECCCCC
PDRLVFNRTIGLRDTFAKEVAKG
CCCEEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure
MMTTTTDTAATAEAGRDFIRDIVQADLDSGRHKTVVTRFPPEPNGYLHIGHAKSIGLNFG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCC
IAREFGGRCNLRFDDTNPTKEEQEYIDSIQADVRWLGYDWGDNLFYASDYFERLYDWAEG
CHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCEEEHHHHHHHHHHHHHH
LIKAGLAYVDDQTQEEIRASRGTLTEPGKNSPFRDRSVEENLDLFRRMKAGEFPNGARVL
HHHCCHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHEE
RAKIDMAAGNINLRDPVLYRILHAHHPRTGDTWKIYPSYDYAHGQSDAIEGVTHSICTLE
EEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHHEEEEEE
FEDHRPLYEWLLDKLPVPSHPRQYEFARLNLTYTLLSKRVLTRLVQDGHVSGWDDPRMPT
ECCCCCHHHHHHHHCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
IAGLKRRGVPPAAVREFTKRIGIAKANSVVDVGMLEFCIREELNRTAQRRMAVLRPLKVL
HHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IENYPEGQVEELEAINHPDDPSAGTRKIAFGRELYIEQDDFMENPPKKFFRLSPGNEVRL
HHCCCCCHHHHHHHCCCCCCCCCCCEEEECCCEEEEECHHHCCCCCHHHEECCCCCCEEE
RYAYFIKCREVIKNDAGEIVELRCTYDPETKGGNAPDGRKVKATMHWLPAAQSLTAEIRL
EHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHH
YNQLFANPSPNAADFTADLNPDSLEVLADARIEPSIAASNSDAPVQFERQGYFVRDPDST
HHHHHCCCCCCCCCEEECCCCCHHHHHCCCCCCCCEECCCCCCCEEECCCCCEEECCCCC
PDRLVFNRTIGLRDTFAKEVAKG
CCCEEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]