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The map label for this gene is trpD [H]

Identifier: 146341038

GI number: 146341038

Start: 4299123

End: 4300139

Strand: Direct

Name: trpD [H]

Synonym: BRADO4109

Alternate gene names: 146341038

Gene position: 4299123-4300139 (Clockwise)

Preceding gene: 146341037

Following gene: 146341039

Centisome position: 57.66

GC content: 68.63

Gene sequence:

>1017_bases
GTGATGGACGATCTGAAGTCGATCATTGGCAAGGTCGCGACCGGCGCGCCGCTGTCCCGCGAGCAGGCTGCGTCCGCCTT
CGACAGCATGATGTCGGGCGAGGCGACGCCGTCGCAGATGGGCGCGTTGCTGATGGCGCTGCGCGTGCGCGGCGAGACCG
TGGAGGAGATCACCGGCGCCGTCAGCGTGATGCGCGCCAAGATGCTGCGCGTCGACGCACCGGCGAACGCCGTCGACATC
GTCGGCACCGGCGGTGACGGCTCCGGCTCGGTCAACGTCTCGACCTGCGCCTCCTTCATCGTGGCCGGTGCCGGCGTGCC
GGTCGCCAAGCACGGCAACCGCGCGCTGTCGTCGCGCTCAGGCGCGGCCGACGTGCTCGCCGCTCTCGGCGTCAAGATCG
ATCTCAAGCCGGACCAGGTCGGACGCTGCATCCGCGAGGCCGGGATCGGCTTCATGTTCGCGCCCGCCCATCACCCGGCG
ATGAAGAACGTCGGCCCGACCCGGGTCGAGCTTGCCACCCGCACCATCTTCAACCTGCTCGGACCGTTGTCCAACCCCGC
TGGCGTCAAGCGCCAGATGGTCGGCGTTTTCTCCAGGCAGTGGGTCGAGCCGCTGGCGCAGGTGCTGAAAAATCTCGGAT
CGGGCGCCGCCTGGGTCGTTCACGGCTCCGACGGTCTCGACGAGATCACGCTGACAGGGCCGACCTTCGTAGCGGCGCTC
GAGAACGGCCATATCAGAACCTTCGAGATCTCGCCGGAAGAGGCCGGGCTTGGCCTGTGCGACAGCGAAGGGCTTAAGGG
CGGTGACGCCGCCGCAAATGCCGTGGCGCTGCAGAGCGTGCTCGACGGCCTGCCAAGCCCCTACCGCGACGTCGCCCTGT
TGAACGCGGCTGCGGCCCTTGTCGTCGCCGGCCGCGCCAAGTCGCTGAAGGAAGGCGTCGCAATCGGCAAGGACTCGCTC
GACAGCGGTGCCGCTGCCGGGCGTCTGAAGCAGCTGATCGCCGTCTCCAACAGCTGA

Upstream 100 bases:

>100_bases
CCTGAAGCTCGAGAAGGACATCGGGACCACGATCAACGAAGCGGCCGTGGCCCAGGTGGTCGGCGGCGGCAGCAATCAGT
GACGGCTCGCGAGGGGACGC

Downstream 100 bases:

>100_bases
CATCAGGAGCGCGCCATGTCGGACATCCTGGCCAAGATCGAAGCCTATAAGCGCGAGGAGATCGCGGCTGCCAAGCAGGC
TTGTCCGCTGTCGGAACTCG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MMDDLKSIIGKVATGAPLSREQAASAFDSMMSGEATPSQMGALLMALRVRGETVEEITGAVSVMRAKMLRVDAPANAVDI
VGTGGDGSGSVNVSTCASFIVAGAGVPVAKHGNRALSSRSGAADVLAALGVKIDLKPDQVGRCIREAGIGFMFAPAHHPA
MKNVGPTRVELATRTIFNLLGPLSNPAGVKRQMVGVFSRQWVEPLAQVLKNLGSGAAWVVHGSDGLDEITLTGPTFVAAL
ENGHIRTFEISPEEAGLGLCDSEGLKGGDAAANAVALQSVLDGLPSPYRDVALLNAAAALVVAGRAKSLKEGVAIGKDSL
DSGAAAGRLKQLIAVSNS

Sequences:

>Translated_338_residues
MMDDLKSIIGKVATGAPLSREQAASAFDSMMSGEATPSQMGALLMALRVRGETVEEITGAVSVMRAKMLRVDAPANAVDI
VGTGGDGSGSVNVSTCASFIVAGAGVPVAKHGNRALSSRSGAADVLAALGVKIDLKPDQVGRCIREAGIGFMFAPAHHPA
MKNVGPTRVELATRTIFNLLGPLSNPAGVKRQMVGVFSRQWVEPLAQVLKNLGSGAAWVVHGSDGLDEITLTGPTFVAAL
ENGHIRTFEISPEEAGLGLCDSEGLKGGDAAANAVALQSVLDGLPSPYRDVALLNAAAALVVAGRAKSLKEGVAIGKDSL
DSGAAAGRLKQLIAVSNS
>Mature_338_residues
MMDDLKSIIGKVATGAPLSREQAASAFDSMMSGEATPSQMGALLMALRVRGETVEEITGAVSVMRAKMLRVDAPANAVDI
VGTGGDGSGSVNVSTCASFIVAGAGVPVAKHGNRALSSRSGAADVLAALGVKIDLKPDQVGRCIREAGIGFMFAPAHHPA
MKNVGPTRVELATRTIFNLLGPLSNPAGVKRQMVGVFSRQWVEPLAQVLKNLGSGAAWVVHGSDGLDEITLTGPTFVAAL
ENGHIRTFEISPEEAGLGLCDSEGLKGGDAAANAVALQSVLDGLPSPYRDVALLNAAAALVVAGRAKSLKEGVAIGKDSL
DSGAAAGRLKQLIAVSNS

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=282, Percent_Identity=40.0709219858156, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI1787019, Length=319, Percent_Identity=21.9435736677116, Blast_Score=62, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320561, Length=332, Percent_Identity=31.0240963855422, Blast_Score=122, Evalue=9e-29,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 34412; Mature: 34412

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDDLKSIIGKVATGAPLSREQAASAFDSMMSGEATPSQMGALLMALRVRGETVEEITGA
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
VSVMRAKMLRVDAPANAVDIVGTGGDGSGSVNVSTCASFIVAGAGVPVAKHGNRALSSRS
HHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCHHHHCCC
GAADVLAALGVKIDLKPDQVGRCIREAGIGFMFAPAHHPAMKNVGPTRVELATRTIFNLL
CHHHHHHHHCCEEECCHHHHHHHHHHCCCCEEECCCCCCHHHCCCCHHHHHHHHHHHHHH
GPLSNPAGVKRQMVGVFSRQWVEPLAQVLKNLGSGAAWVVHGSDGLDEITLTGPTFVAAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCEEEEEE
ENGHIRTFEISPEEAGLGLCDSEGLKGGDAAANAVALQSVLDGLPSPYRDVALLNAAAAL
CCCCEEEEEECHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
VVAGRAKSLKEGVAIGKDSLDSGAAAGRLKQLIAVSNS
HHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMDDLKSIIGKVATGAPLSREQAASAFDSMMSGEATPSQMGALLMALRVRGETVEEITGA
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
VSVMRAKMLRVDAPANAVDIVGTGGDGSGSVNVSTCASFIVAGAGVPVAKHGNRALSSRS
HHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCHHHHCCC
GAADVLAALGVKIDLKPDQVGRCIREAGIGFMFAPAHHPAMKNVGPTRVELATRTIFNLL
CHHHHHHHHCCEEECCHHHHHHHHHHCCCCEEECCCCCCHHHCCCCHHHHHHHHHHHHHH
GPLSNPAGVKRQMVGVFSRQWVEPLAQVLKNLGSGAAWVVHGSDGLDEITLTGPTFVAAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCEEEEEE
ENGHIRTFEISPEEAGLGLCDSEGLKGGDAAANAVALQSVLDGLPSPYRDVALLNAAAAL
CCCCEEEEEECHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
VVAGRAKSLKEGVAIGKDSLDSGAAAGRLKQLIAVSNS
HHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA