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The map label for this gene is ppiD [H]

Identifier: 146341037

GI number: 146341037

Start: 4297194

End: 4299104

Strand: Direct

Name: ppiD [H]

Synonym: BRADO4108

Alternate gene names: 146341037

Gene position: 4297194-4299104 (Clockwise)

Preceding gene: 146341035

Following gene: 146341038

Centisome position: 57.63

GC content: 66.35

Gene sequence:

>1911_bases
ATGCTTCGAGGATTACGCAAGGCCTCATCAAACTGGCTCGGCAAGACCATCATGGCGGTGGTCATGGGCGTTTTGATCGT
CAGTTTCGGCATCTGGGGCATCGCCGACATCTTCCGTGGCTTCGGGCAGTCGACAGCGGCGACCGTCGGCCGCACCGAGA
TCTCGATCAACGAGTTCCGTCAGATCTACACCGACCGGCTGCAGCAGATCGGCCGCCAGATCGGCCGTCCGCTGACCACC
GACCAGGCCCGCATGTTCGGGCTCGACCGTTCCGTGCTGCAGCAGACGATCGCGGAAGCCGCGCTCGACGAACAGGCCCG
CCGCATCGGCCTCGGCCAGTCCGACGCCGAGACCATGCGGGTGATCCTGAGCGATCCCAACTTCAAGGGCCCGAACGGCG
CCTTCGATCCGCAGCGCTTCCAGGCCATCATCCGCAATTTCGGCTTCACGGAGCAGCGCTATCTGGCCGACCAGCGCCGC
CAGTCGCTGCGGCGGCAGATCACCGGCACGATCGCAGCCGGGCTGGAGCCTTCCAACACCTTGCTCGACGCACTCAGCCG
CTTCCAGAACGAGCAGCGCTCGATCGACTACGTCAAGCTCGACGCCGCACAGGCCGGCACGATCGAGACGCCGGCGCCCG
AGGTGCTCGCGACCTATTTCGACGAGCACAAGGCGCAGTTCAAGGCGCCGGAATATCGCAAGATCTCGTTCGTCCTGGTG
ACGCCGGAAGAGATTGGCAAATGGACCACCGTGTCCGACGAGGATGCCAGGAAGGTCTTCGATCAGCGCAAGGCGCTGAT
GGGCACGCCCGAGAAACGTCAGGTCCAGCAGATGACGTTCCCGACCATGGAGGAGGCGCAGGCGGCACGCGCGCGCATCG
CCTCTGGCGAGGTGACGTTCGACGAGCTCGCCAAGGAGCGCAACCTGAACCCGGCCGATCTCGACCTTGGGCTGGTGACG
AAGTCCGCCATTCTCGATCCCGCCGTTGCCGATACCGCGTTCTCGCTGCCGACCGGCGAGGTGAGCCAGCCGGTCAAGGG
CGCCTTCAACGTGGCGCTGGTGAAGGTGAGCGCGATCCAGCCGGGCCAGGAGCCGGCGTATGAGAGCGTCGCTGCCGACA
TCAAGAAGGAGATCGCCGCCGAGCGCGCCAAGTCGGAGGTCGCCACCTTGCGCGACAAGATGGAGGACGAGCGCGGCGGC
GGTGCGAGCGTCGCCGAAGCCGCCAAAAAGCTCGGCCTCAATGCGGTGACGGTCGAGGCGGTCGACCGCTCCGGCAAGCA
GCCCGACGGCCAGCCGGTGCCGAACATTCCGCTCGGCCTCGACGTCGTCGCCCAGGCCTTCGCCAGCGATGTCGGCGTCG
ACAATGAGCCCATCTCGTTCCGCGGCGGCTACGTCTGGTTCGAAGTGCTCGGCATCACGCCGCCGCGCGAGCGCACCCTC
GACGAGGTCAAGGACCAGGTCGCCGCCAAATGGCGCGACGACGAGATCGCAAAGCGGCTGCGCGACAGGGCCACGGAGCT
CGTCAAGAAGCTCAACGAGGGCGGCAAGCTTGCCGACGAGGCAGCCGCGCTCGGCGTCAAGGTCGAGACCGCCAGCGCCT
TCAAGCGCGATGCAAGCCTCCCCGGCGTGCCCACCGGCGCAATCACCGCGACTTTCCGCACCGCCAAGGACGGCGTCGGC
CAGACCGAAGCGGATGGCGGCCGGCAGTGGATCGTGTTCCGCGTGACCGACATCGTCGATCCAAAGGTCGATTTGGCGTC
CGAGGACGTCAAGAAGCTCAAGGACCAGCTGCAACGCGCGCTCGCCGACGAGCAGGGCACGTCGTATGTCCTGAAGCTCG
AGAAGGACATCGGGACCACGATCAACGAAGCGGCCGTGGCCCAGGTGGTCGGCGGCGGCAGCAATCAGTGA

Upstream 100 bases:

>100_bases
CTGCCTCTTTATAAGCCGGTTCAACTCGGTGACGCCCTTCCGCGAACTCCGCTCCAAGGCGCGGCCCCTTCATCCCATTT
CCTGCAGACAGACTGGACCC

Downstream 100 bases:

>100_bases
CGGCTCGCGAGGGGACGCGTGATGGACGATCTGAAGTCGATCATTGGCAAGGTCGCGACCGGCGCGCCGCTGTCCCGCGA
GCAGGCTGCGTCCGCCTTCG

Product: putative peptidylprolyl isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 636; Mature: 636

Protein sequence:

>636_residues
MLRGLRKASSNWLGKTIMAVVMGVLIVSFGIWGIADIFRGFGQSTAATVGRTEISINEFRQIYTDRLQQIGRQIGRPLTT
DQARMFGLDRSVLQQTIAEAALDEQARRIGLGQSDAETMRVILSDPNFKGPNGAFDPQRFQAIIRNFGFTEQRYLADQRR
QSLRRQITGTIAAGLEPSNTLLDALSRFQNEQRSIDYVKLDAAQAGTIETPAPEVLATYFDEHKAQFKAPEYRKISFVLV
TPEEIGKWTTVSDEDARKVFDQRKALMGTPEKRQVQQMTFPTMEEAQAARARIASGEVTFDELAKERNLNPADLDLGLVT
KSAILDPAVADTAFSLPTGEVSQPVKGAFNVALVKVSAIQPGQEPAYESVAADIKKEIAAERAKSEVATLRDKMEDERGG
GASVAEAAKKLGLNAVTVEAVDRSGKQPDGQPVPNIPLGLDVVAQAFASDVGVDNEPISFRGGYVWFEVLGITPPRERTL
DEVKDQVAAKWRDDEIAKRLRDRATELVKKLNEGGKLADEAAALGVKVETASAFKRDASLPGVPTGAITATFRTAKDGVG
QTEADGGRQWIVFRVTDIVDPKVDLASEDVKKLKDQLQRALADEQGTSYVLKLEKDIGTTINEAAVAQVVGGGSNQ

Sequences:

>Translated_636_residues
MLRGLRKASSNWLGKTIMAVVMGVLIVSFGIWGIADIFRGFGQSTAATVGRTEISINEFRQIYTDRLQQIGRQIGRPLTT
DQARMFGLDRSVLQQTIAEAALDEQARRIGLGQSDAETMRVILSDPNFKGPNGAFDPQRFQAIIRNFGFTEQRYLADQRR
QSLRRQITGTIAAGLEPSNTLLDALSRFQNEQRSIDYVKLDAAQAGTIETPAPEVLATYFDEHKAQFKAPEYRKISFVLV
TPEEIGKWTTVSDEDARKVFDQRKALMGTPEKRQVQQMTFPTMEEAQAARARIASGEVTFDELAKERNLNPADLDLGLVT
KSAILDPAVADTAFSLPTGEVSQPVKGAFNVALVKVSAIQPGQEPAYESVAADIKKEIAAERAKSEVATLRDKMEDERGG
GASVAEAAKKLGLNAVTVEAVDRSGKQPDGQPVPNIPLGLDVVAQAFASDVGVDNEPISFRGGYVWFEVLGITPPRERTL
DEVKDQVAAKWRDDEIAKRLRDRATELVKKLNEGGKLADEAAALGVKVETASAFKRDASLPGVPTGAITATFRTAKDGVG
QTEADGGRQWIVFRVTDIVDPKVDLASEDVKKLKDQLQRALADEQGTSYVLKLEKDIGTTINEAAVAQVVGGGSNQ
>Mature_636_residues
MLRGLRKASSNWLGKTIMAVVMGVLIVSFGIWGIADIFRGFGQSTAATVGRTEISINEFRQIYTDRLQQIGRQIGRPLTT
DQARMFGLDRSVLQQTIAEAALDEQARRIGLGQSDAETMRVILSDPNFKGPNGAFDPQRFQAIIRNFGFTEQRYLADQRR
QSLRRQITGTIAAGLEPSNTLLDALSRFQNEQRSIDYVKLDAAQAGTIETPAPEVLATYFDEHKAQFKAPEYRKISFVLV
TPEEIGKWTTVSDEDARKVFDQRKALMGTPEKRQVQQMTFPTMEEAQAARARIASGEVTFDELAKERNLNPADLDLGLVT
KSAILDPAVADTAFSLPTGEVSQPVKGAFNVALVKVSAIQPGQEPAYESVAADIKKEIAAERAKSEVATLRDKMEDERGG
GASVAEAAKKLGLNAVTVEAVDRSGKQPDGQPVPNIPLGLDVVAQAFASDVGVDNEPISFRGGYVWFEVLGITPPRERTL
DEVKDQVAAKWRDDEIAKRLRDRATELVKKLNEGGKLADEAAALGVKVETASAFKRDASLPGVPTGAITATFRTAKDGVG
QTEADGGRQWIVFRVTDIVDPKVDLASEDVKKLKDQLQRALADEQGTSYVLKLEKDIGTTINEAAVAQVVGGGSNQ

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=562, Percent_Identity=25.0889679715303, Blast_Score=135, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 69232; Mature: 69232

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRGLRKASSNWLGKTIMAVVMGVLIVSFGIWGIADIFRGFGQSTAATVGRTEISINEFR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHH
QIYTDRLQQIGRQIGRPLTTDQARMFGLDRSVLQQTIAEAALDEQARRIGLGQSDAETMR
HHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHE
VILSDPNFKGPNGAFDPQRFQAIIRNFGFTEQRYLADQRRQSLRRQITGTIAAGLEPSNT
EEECCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LLDALSRFQNEQRSIDYVKLDAAQAGTIETPAPEVLATYFDEHKAQFKAPEYRKISFVLV
HHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEE
TPEEIGKWTTVSDEDARKVFDQRKALMGTPEKRQVQQMTFPTMEEAQAARARIASGEVTF
CHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCH
DELAKERNLNPADLDLGLVTKSAILDPAVADTAFSLPTGEVSQPVKGAFNVALVKVSAIQ
HHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCCCCCCCCHHHCCEEEEEEEECCC
PGQEPAYESVAADIKKEIAAERAKSEVATLRDKMEDERGGGASVAEAAKKLGLNAVTVEA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEE
VDRSGKQPDGQPVPNIPLGLDVVAQAFASDVGVDNEPISFRGGYVWFEVLGITPPRERTL
HHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHH
DEVKDQVAAKWRDDEIAKRLRDRATELVKKLNEGGKLADEAAALGVKVETASAFKRDASL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCEEEEHHHHHHHCCCC
PGVPTGAITATFRTAKDGVGQTEADGGRQWIVFRVTDIVDPKVDLASEDVKKLKDQLQRA
CCCCCCCCEEEEHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
LADEQGTSYVLKLEKDIGTTINEAAVAQVVGGGSNQ
HHCCCCCEEEEEECHHHCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLRGLRKASSNWLGKTIMAVVMGVLIVSFGIWGIADIFRGFGQSTAATVGRTEISINEFR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHH
QIYTDRLQQIGRQIGRPLTTDQARMFGLDRSVLQQTIAEAALDEQARRIGLGQSDAETMR
HHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHE
VILSDPNFKGPNGAFDPQRFQAIIRNFGFTEQRYLADQRRQSLRRQITGTIAAGLEPSNT
EEECCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LLDALSRFQNEQRSIDYVKLDAAQAGTIETPAPEVLATYFDEHKAQFKAPEYRKISFVLV
HHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEE
TPEEIGKWTTVSDEDARKVFDQRKALMGTPEKRQVQQMTFPTMEEAQAARARIASGEVTF
CHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCH
DELAKERNLNPADLDLGLVTKSAILDPAVADTAFSLPTGEVSQPVKGAFNVALVKVSAIQ
HHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCCCCCCCCHHHCCEEEEEEEECCC
PGQEPAYESVAADIKKEIAAERAKSEVATLRDKMEDERGGGASVAEAAKKLGLNAVTVEA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEE
VDRSGKQPDGQPVPNIPLGLDVVAQAFASDVGVDNEPISFRGGYVWFEVLGITPPRERTL
HHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHH
DEVKDQVAAKWRDDEIAKRLRDRATELVKKLNEGGKLADEAAALGVKVETASAFKRDASL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCEEEEHHHHHHHCCCC
PGVPTGAITATFRTAKDGVGQTEADGGRQWIVFRVTDIVDPKVDLASEDVKKLKDQLQRA
CCCCCCCCEEEEHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
LADEQGTSYVLKLEKDIGTTINEAAVAQVVGGGSNQ
HHCCCCCEEEEEECHHHCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]