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The map label for this gene is yraA [H]

Identifier: 146340883

GI number: 146340883

Start: 4131567

End: 4132127

Strand: Reverse

Name: yraA [H]

Synonym: BRADO3949

Alternate gene names: 146340883

Gene position: 4132127-4131567 (Counterclockwise)

Preceding gene: 146340887

Following gene: 146340882

Centisome position: 55.42

GC content: 60.43

Gene sequence:

>561_bases
ATGGACATCAAGGGAAAAAGGATTGCGATCCTCGCGACCAACGGTTTCGAGCAATCCGAGTTGGAAGTGCCGCGCGATCG
CCTGTCGCAGGCTGGAGCGACGGTGGAGATCGTTTCGCTTGCGCCGGGCGAGATCAAAGGATGGGACCAGAAGGACTGGG
GCAGGCCGGTCAAGGTCGACAAGACGCTCGACCAGGCGCAAGCGTCCGATTATGACGCCATCGTGCTCCCGGGCGGCCAG
ATCAATCCGGATCTGCTGCGCCTCGAGCCGAAGGCGCTGCAGTTCATCAAGGACATCTTCAATGCCAAGAAGATCGTGGC
TGCGGTCTGCCATGCGCCGTGGCTGCTGATTGAGACCGGCATCGCGAAGGGGCGTAAAATGACGTCCTATAAATCCATCA
AGACGGACGTCGCCAATGCCGGCGCCCAGTGGCAGGACGCGGAAGTCGTCGTCGACCAAGGCGTCATCACGTCGCGCAAT
CCCGGCGATCTCGAAGCGTTCAGTGCCAAGATCATCGAAGAGGTGAAGGAAGGCCGGCATCTGCAACGGAGCGCCGCTTA
A

Upstream 100 bases:

>100_bases
CGATCGACCAGTTGTGACAATCGGCCATCGATCGCTGCGGAACGATGGGCGCATGCGCAATGTTGCCCGCCGTCATCGAC
CCAAAACGAGAGCATCTGTC

Downstream 100 bases:

>100_bases
GGCGATGTCTTGGACGAGGCCGGAGCCTGCCTGGCCTCGTCCAAGGACAGGCCCAGCGCCCGAGGGGTCGAACGCTGGGC
CGCAGTCCACACGGAGTGTC

Product: putative intracellular proteinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MDIKGKRIAILATNGFEQSELEVPRDRLSQAGATVEIVSLAPGEIKGWDQKDWGRPVKVDKTLDQAQASDYDAIVLPGGQ
INPDLLRLEPKALQFIKDIFNAKKIVAAVCHAPWLLIETGIAKGRKMTSYKSIKTDVANAGAQWQDAEVVVDQGVITSRN
PGDLEAFSAKIIEEVKEGRHLQRSAA

Sequences:

>Translated_186_residues
MDIKGKRIAILATNGFEQSELEVPRDRLSQAGATVEIVSLAPGEIKGWDQKDWGRPVKVDKTLDQAQASDYDAIVLPGGQ
INPDLLRLEPKALQFIKDIFNAKKIVAAVCHAPWLLIETGIAKGRKMTSYKSIKTDVANAGAQWQDAEVVVDQGVITSRN
PGDLEAFSAKIIEEVKEGRHLQRSAA
>Mature_186_residues
MDIKGKRIAILATNGFEQSELEVPRDRLSQAGATVEIVSLAPGEIKGWDQKDWGRPVKVDKTLDQAQASDYDAIVLPGGQ
INPDLLRLEPKALQFIKDIFNAKKIVAAVCHAPWLLIETGIAKGRKMTSYKSIKTDVANAGAQWQDAEVVVDQGVITSRN
PGDLEAFSAKIIEEVKEGRHLQRSAA

Specific function: Functions in the protection against aldehyde-stress, possibly by degrading damaged proteins [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=172, Percent_Identity=30.2325581395349, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI31543380, Length=172, Percent_Identity=30.2325581395349, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI87082219, Length=165, Percent_Identity=42.4242424242424, Blast_Score=127, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17531319, Length=175, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28571932, Length=182, Percent_Identity=30.2197802197802, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24653499, Length=175, Percent_Identity=29.1428571428571, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 20328; Mature: 20328

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKGKRIAILATNGFEQSELEVPRDRLSQAGATVEIVSLAPGEIKGWDQKDWGRPVKVD
CCCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCEEEH
KTLDQAQASDYDAIVLPGGQINPDLLRLEPKALQFIKDIFNAKKIVAAVCHAPWLLIETG
HHHHHHHCCCCCEEEECCCCCCHHHEEECHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHH
IAKGRKMTSYKSIKTDVANAGAQWQDAEVVVDQGVITSRNPGDLEAFSAKIIEEVKEGRH
HCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCEECCCCCCCHHHHHHHHHHHHHHCCH
LQRSAA
HHHCCC
>Mature Secondary Structure
MDIKGKRIAILATNGFEQSELEVPRDRLSQAGATVEIVSLAPGEIKGWDQKDWGRPVKVD
CCCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCEEEH
KTLDQAQASDYDAIVLPGGQINPDLLRLEPKALQFIKDIFNAKKIVAAVCHAPWLLIETG
HHHHHHHCCCCCEEEECCCCCCHHHEEECHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHH
IAKGRKMTSYKSIKTDVANAGAQWQDAEVVVDQGVITSRNPGDLEAFSAKIIEEVKEGRH
HCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCEECCCCCCCHHHHHHHHHHHHHHCCH
LQRSAA
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377; 10568751 [H]