Click here to switch to the map view.

The map label for this gene is hfq [H]

Identifier: 146340796

GI number: 146340796

Start: 4028001

End: 4028249

Strand: Reverse

Name: hfq [H]

Synonym: BRADO3855

Alternate gene names: 146340796

Gene position: 4028249-4028001 (Counterclockwise)

Preceding gene: 146340797

Following gene: 146340795

Centisome position: 54.02

GC content: 59.44

Gene sequence:

>249_bases
ATGGCGGCAGACCGCGCACAAAACCTACAAGACACGTTTCTGAACCACGTCCGAAAGACCAAGACACCGCTCACCATCTT
CCTGGTCAACGGCGTGAAACTGCAGGGGATTGTCACATGGTTCGACAATTTCTGCCTGTTGCTCCGGCGCGACGGCCACT
CGCAGCTCGTCTACAAGCATGCGATCTCCACCATCATGCCGGGCGCTCCGATTCAGCTGTTCGAGGGCGGCGAGGACGCC
TCCGCGTGA

Upstream 100 bases:

>100_bases
GGATCTCAATGGATCATGGGTCACCGCGACGGCACCGAGGCCGGCAATCGGGTCGCCGCAGGTCCAATAAGAAAAAGCAC
AAGACTGCGAGATAACAACA

Downstream 100 bases:

>100_bases
GAGTGATCTGATTGGAACCCCGCGATCGCGATGGGACCATCGGCCTTGCGAGGCCGGATGACGTCAAGACAACGGGCCGA
GTCATCGTGGTCGGCCCGTA

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 82; Mature: 81

Protein sequence:

>82_residues
MAADRAQNLQDTFLNHVRKTKTPLTIFLVNGVKLQGIVTWFDNFCLLLRRDGHSQLVYKHAISTIMPGAPIQLFEGGEDA
SA

Sequences:

>Translated_82_residues
MAADRAQNLQDTFLNHVRKTKTPLTIFLVNGVKLQGIVTWFDNFCLLLRRDGHSQLVYKHAISTIMPGAPIQLFEGGEDA
SA
>Mature_81_residues
AADRAQNLQDTFLNHVRKTKTPLTIFLVNGVKLQGIVTWFDNFCLLLRRDGHSQLVYKHAISTIMPGAPIQLFEGGEDAS
A

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=67, Percent_Identity=52.2388059701493, Blast_Score=81, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 9141; Mature: 9009

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAADRAQNLQDTFLNHVRKTKTPLTIFLVNGVKLQGIVTWFDNFCLLLRRDGHSQLVYKH
CCCCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEEHHHHHHHHHEEEEECCCCCHHHHHH
AISTIMPGAPIQLFEGGEDASA
HHHHHCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
AADRAQNLQDTFLNHVRKTKTPLTIFLVNGVKLQGIVTWFDNFCLLLRRDGHSQLVYKH
CCCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEEHHHHHHHHHEEEEECCCCCHHHHHH
AISTIMPGAPIQLFEGGEDASA
HHHHHCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]