Click here to switch to the map view.

The map label for this gene is hflX [H]

Identifier: 146340795

GI number: 146340795

Start: 4026610

End: 4027989

Strand: Reverse

Name: hflX [H]

Synonym: BRADO3854

Alternate gene names: 146340795

Gene position: 4027989-4026610 (Counterclockwise)

Preceding gene: 146340796

Following gene: 146340793

Centisome position: 54.02

GC content: 67.25

Gene sequence:

>1380_bases
TTGGAACCCCGCGATCGCGATGGGACCATCGGCCTTGCGAGGCCGGATGACGTCAAGACAACGGGCCGAGTCATCGTGGT
CGGCCCGTATTTGCGGACACGCCGTGGCGACGACGGCGCGCCGGCCAGCCACTCCGAAATGCGCGATGTCGAGGCGCGGA
TCGACGAGGCCGCGGGGCTCGCGCGCGCGATCAATCTCACCGTCGCCGAATCCATTCTCGCGCTGATCGGACAGATCCGT
CCGGCGACCTATCTCGGCAAGGGAAAGGTCGACGAGATCGCCGGCGTGATCGCGAGCCAGGAGGCCGAGCTCGTCGTGAT
GGATTGCGCGCTGTCGCCGATCCAGCAGCGCAATCTGGAGAAGGCCTGGAACACCAAGGTGCTCGACCGCACCGGCCTCA
TCCTCGAAATCTTCGGCCGCCGCGCCAAGACCAAGGAGGGCGCGCTGCAGGTCGAGCTCGCGCATCTCAACTATCAGCGC
AGCCGCCTGGTGCGGTCATGGACCCATCTCGAGCGCCAGCGCGGCGGCTTCGGCTTCATGGGCGGCCCGGGTGAGACCCA
GATCGAGGCCGACCGCCGGCTGATCGGCGACCGCATCACCCGGCTCGAGAACGAATTGAAGAAGGTGCAGGCGACGCGCC
GGCTGCATCGCGCCGGCCGCCAGCGCGTGCCGTATCGCGTGGTCGCGCTGGTCGGCTACACCAATGCCGGCAAGTCGACG
CTGTTCAACCGCCTGACGCGTGCCGACGTGCAGGCCGCCGACATGCTGTTCGCGACGCTCGATCCGACCCTGCGCGCGAT
CAGCCTGCCGCATGGTGGCAAGGCGATGCTGTCGGACACCGTCGGCTTCATCTCCAATCTGCCGACGCAACTCGTCGCTG
CTTTCCGCGCGACGCTGGAGGAGGTGCTGGAGGCCGACGTCATCCTGCATGTCCGCGACATGTCGCATGAGGATGCGGAG
GCGCAGCAGCACGACGTCGAGCTGGTGCTCAGCCAGCTCGGCATCGATCCCGAGGCGACCGACACCATCATCGAGGTCTG
GAACAAGATCGACCGGCTCGACGACGCCGCGCGCGAGAACCTCGCCAACATCGCCGCACGCCGCCCACCCGAGCGGCCCT
GCTTCATGGTGTCGGCCGAGACAGGGGAGGGTGTCGACGCCCTGCTGCAGGCGATCGAAGACCGCCTCGCGGCGGCACGC
ACGACGCTCGACCTGACGATCGACGCCGCCGACGGCGCCGGCATCAGCTGGCTCCACCGCAATGCCGAGGTGCTCAGCAA
GGAGCTGCACGAGGGCCACTACGACATGACCGTGCGCGTCGACGCGACCAAGCGGGATATTGTCGTTGAGAGGTATCATG
GTATTCCAAGGGTGGCTTGA

Upstream 100 bases:

>100_bases
CGCAGCTCGTCTACAAGCATGCGATCTCCACCATCATGCCGGGCGCTCCGATTCAGCTGTTCGAGGGCGGCGAGGACGCC
TCCGCGTGAGAGTGATCTGA

Downstream 100 bases:

>100_bases
GCCAGTCAGGCTGCCCTTCAGCTCGTGTTGGTTTGCTCGCGGCTTGAAACAAGACCAGCCAAACCTTATACTCAAAGACA
GCCTAGGAGGTAGACCATGA

Product: putative GTP-binding protein (hflX)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MEPRDRDGTIGLARPDDVKTTGRVIVVGPYLRTRRGDDGAPASHSEMRDVEARIDEAAGLARAINLTVAESILALIGQIR
PATYLGKGKVDEIAGVIASQEAELVVMDCALSPIQQRNLEKAWNTKVLDRTGLILEIFGRRAKTKEGALQVELAHLNYQR
SRLVRSWTHLERQRGGFGFMGGPGETQIEADRRLIGDRITRLENELKKVQATRRLHRAGRQRVPYRVVALVGYTNAGKST
LFNRLTRADVQAADMLFATLDPTLRAISLPHGGKAMLSDTVGFISNLPTQLVAAFRATLEEVLEADVILHVRDMSHEDAE
AQQHDVELVLSQLGIDPEATDTIIEVWNKIDRLDDAARENLANIAARRPPERPCFMVSAETGEGVDALLQAIEDRLAAAR
TTLDLTIDAADGAGISWLHRNAEVLSKELHEGHYDMTVRVDATKRDIVVERYHGIPRVA

Sequences:

>Translated_459_residues
MEPRDRDGTIGLARPDDVKTTGRVIVVGPYLRTRRGDDGAPASHSEMRDVEARIDEAAGLARAINLTVAESILALIGQIR
PATYLGKGKVDEIAGVIASQEAELVVMDCALSPIQQRNLEKAWNTKVLDRTGLILEIFGRRAKTKEGALQVELAHLNYQR
SRLVRSWTHLERQRGGFGFMGGPGETQIEADRRLIGDRITRLENELKKVQATRRLHRAGRQRVPYRVVALVGYTNAGKST
LFNRLTRADVQAADMLFATLDPTLRAISLPHGGKAMLSDTVGFISNLPTQLVAAFRATLEEVLEADVILHVRDMSHEDAE
AQQHDVELVLSQLGIDPEATDTIIEVWNKIDRLDDAARENLANIAARRPPERPCFMVSAETGEGVDALLQAIEDRLAAAR
TTLDLTIDAADGAGISWLHRNAEVLSKELHEGHYDMTVRVDATKRDIVVERYHGIPRVA
>Mature_459_residues
MEPRDRDGTIGLARPDDVKTTGRVIVVGPYLRTRRGDDGAPASHSEMRDVEARIDEAAGLARAINLTVAESILALIGQIR
PATYLGKGKVDEIAGVIASQEAELVVMDCALSPIQQRNLEKAWNTKVLDRTGLILEIFGRRAKTKEGALQVELAHLNYQR
SRLVRSWTHLERQRGGFGFMGGPGETQIEADRRLIGDRITRLENELKKVQATRRLHRAGRQRVPYRVVALVGYTNAGKST
LFNRLTRADVQAADMLFATLDPTLRAISLPHGGKAMLSDTVGFISNLPTQLVAAFRATLEEVLEADVILHVRDMSHEDAE
AQQHDVELVLSQLGIDPEATDTIIEVWNKIDRLDDAARENLANIAARRPPERPCFMVSAETGEGVDALLQAIEDRLAAAR
TTLDLTIDAADGAGISWLHRNAEVLSKELHEGHYDMTVRVDATKRDIVVERYHGIPRVA

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=320, Percent_Identity=35, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI310133116, Length=265, Percent_Identity=36.6037735849057, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI310124269, Length=246, Percent_Identity=36.9918699186992, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI310124267, Length=246, Percent_Identity=36.9918699186992, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI310124171, Length=246, Percent_Identity=36.9918699186992, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI310124169, Length=246, Percent_Identity=36.9918699186992, Blast_Score=140, Evalue=3e-33,
Organism=Escherichia coli, GI1790615, Length=327, Percent_Identity=48.9296636085627, Blast_Score=273, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17561038, Length=419, Percent_Identity=31.980906921241, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24650079, Length=427, Percent_Identity=31.3817330210773, Blast_Score=164, Evalue=9e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50700; Mature: 50700

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPRDRDGTIGLARPDDVKTTGRVIVVGPYLRTRRGDDGAPASHSEMRDVEARIDEAAGL
CCCCCCCCEEECCCCCCCCCCCEEEEECCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
ARAINLTVAESILALIGQIRPATYLGKGKVDEIAGVIASQEAELVVMDCALSPIQQRNLE
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHH
KAWNTKVLDRTGLILEIFGRRAKTKEGALQVELAHLNYQRSRLVRSWTHLERQRGGFGFM
HHHCCHHHHCCCHHHHHHCCCCCCCCCCEEEEEEHHCHHHHHHHHHHHHHHHHCCCCCCC
GGPGETQIEADRRLIGDRITRLENELKKVQATRRLHRAGRQRVPYRVVALVGYTNAGKST
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHH
LFNRLTRADVQAADMLFATLDPTLRAISLPHGGKAMLSDTVGFISNLPTQLVAAFRATLE
HHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
EVLEADVILHVRDMSHEDAEAQQHDVELVLSQLGIDPEATDTIIEVWNKIDRLDDAAREN
HHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LANIAARRPPERPCFMVSAETGEGVDALLQAIEDRLAAARTTLDLTIDAADGAGISWLHR
HHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCCHHHHHH
NAEVLSKELHEGHYDMTVRVDATKRDIVVERYHGIPRVA
HHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEPRDRDGTIGLARPDDVKTTGRVIVVGPYLRTRRGDDGAPASHSEMRDVEARIDEAAGL
CCCCCCCCEEECCCCCCCCCCCEEEEECCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
ARAINLTVAESILALIGQIRPATYLGKGKVDEIAGVIASQEAELVVMDCALSPIQQRNLE
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHH
KAWNTKVLDRTGLILEIFGRRAKTKEGALQVELAHLNYQRSRLVRSWTHLERQRGGFGFM
HHHCCHHHHCCCHHHHHHCCCCCCCCCCEEEEEEHHCHHHHHHHHHHHHHHHHCCCCCCC
GGPGETQIEADRRLIGDRITRLENELKKVQATRRLHRAGRQRVPYRVVALVGYTNAGKST
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHH
LFNRLTRADVQAADMLFATLDPTLRAISLPHGGKAMLSDTVGFISNLPTQLVAAFRATLE
HHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
EVLEADVILHVRDMSHEDAEAQQHDVELVLSQLGIDPEATDTIIEVWNKIDRLDDAAREN
HHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LANIAARRPPERPCFMVSAETGEGVDALLQAIEDRLAAARTTLDLTIDAADGAGISWLHR
HHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCCHHHHHH
NAEVLSKELHEGHYDMTVRVDATKRDIVVERYHGIPRVA
HHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]