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The map label for this gene is btuE [C]

Identifier: 146340344

GI number: 146340344

Start: 3566081

End: 3566662

Strand: Reverse

Name: btuE [C]

Synonym: BRADO3371

Alternate gene names: 146340344

Gene position: 3566662-3566081 (Counterclockwise)

Preceding gene: 146340345

Following gene: 146340343

Centisome position: 47.83

GC content: 65.12

Gene sequence:

>582_bases
ATGATGATCGATCGCAGGATGGTTGTTCTCGGCCTCGGCGCGTCCTTGTCCGGCGCGATGATCGCCTCGCGCGTCGCGCA
GGCAGAGAATGCGGCGGTGAGCAAGTCGACGGCCTACCGGTTCTCCTTCCCGGTGCCCTCCGGCGAGCCGATTCGGCTGG
CCGATTTCGCCGGCAAGCCGGTGCTGGTCGTGAACACGGCGTCGCAGTGCGGCTACACACCCCAATATACCGGGCTGCAG
AAGCTCTGGAGCGAGTTCCACGAGCGCGGCTTGACGATCATCGCCGTCCCCTCCAACGACTTCAACCAGGAGCCGGGCGT
CGGAGGCGACATCGCCGAGCTCGCCAACAAGGAATACGGTGTGACCTTCCCGATGACGGCCAAGGCTGTGGTCACCGGCT
CCAATGCTCATCCATTCTACCGCTGGGCCGCCGAAGCGCGTCCCAAGGACACCCCGCGCTGGAACTTTCATAAATACCTG
GTCGGCCGCGACGGCTACATCGCCGACGTGTTCGCGTCCTCGGTGGAGCCGACCGATACCCGGGTGAAGACCGCCATCGC
CCGGATGCTCGCCGAAGGCTGA

Upstream 100 bases:

>100_bases
GAGCAGTCTGATCCAACGCGAACGCGTGGCCGTTTGACAAGCGGCCGGCGCGCGTTGGAGCATTCTTGCTGACGGGGCTG
GTCTGCACAGGGAGATGCAC

Downstream 100 bases:

>100_bases
GCAACCCGTTTAGGCAACACTTGGCAAGAATGCGGCGGAAGCCGGCAACTTCCCCGCGTTTTCGCCTCGTTTCCTTTTGG
CGCCGGTCCGGCGGCTGGGC

Product: putative glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MMIDRRMVVLGLGASLSGAMIASRVAQAENAAVSKSTAYRFSFPVPSGEPIRLADFAGKPVLVVNTASQCGYTPQYTGLQ
KLWSEFHERGLTIIAVPSNDFNQEPGVGGDIAELANKEYGVTFPMTAKAVVTGSNAHPFYRWAAEARPKDTPRWNFHKYL
VGRDGYIADVFASSVEPTDTRVKTAIARMLAEG

Sequences:

>Translated_193_residues
MMIDRRMVVLGLGASLSGAMIASRVAQAENAAVSKSTAYRFSFPVPSGEPIRLADFAGKPVLVVNTASQCGYTPQYTGLQ
KLWSEFHERGLTIIAVPSNDFNQEPGVGGDIAELANKEYGVTFPMTAKAVVTGSNAHPFYRWAAEARPKDTPRWNFHKYL
VGRDGYIADVFASSVEPTDTRVKTAIARMLAEG
>Mature_193_residues
MMIDRRMVVLGLGASLSGAMIASRVAQAENAAVSKSTAYRFSFPVPSGEPIRLADFAGKPVLVVNTASQCGYTPQYTGLQ
KLWSEFHERGLTIIAVPSNDFNQEPGVGGDIAELANKEYGVTFPMTAKAVVTGSNAHPFYRWAAEARPKDTPRWNFHKYL
VGRDGYIADVFASSVEPTDTRVKTAIARMLAEG

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=146, Percent_Identity=38.3561643835616, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI192455698, Length=159, Percent_Identity=34.5911949685535, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI75709200, Length=170, Percent_Identity=34.7058823529412, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI90903240, Length=149, Percent_Identity=34.8993288590604, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI90903238, Length=152, Percent_Identity=36.1842105263158, Blast_Score=77, Evalue=9e-15,
Organism=Escherichia coli, GI1788003, Length=170, Percent_Identity=35.2941176470588, Blast_Score=105, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17506887, Length=162, Percent_Identity=32.7160493827161, Blast_Score=97, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17535473, Length=140, Percent_Identity=34.2857142857143, Blast_Score=93, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI71993584, Length=160, Percent_Identity=32.5, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI193210707, Length=183, Percent_Identity=30.0546448087432, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17550320, Length=217, Percent_Identity=25.8064516129032, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193209493, Length=204, Percent_Identity=25.9803921568627, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319721, Length=160, Percent_Identity=33.75, Blast_Score=112, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6322228, Length=151, Percent_Identity=36.4238410596026, Blast_Score=110, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6322826, Length=146, Percent_Identity=32.8767123287671, Blast_Score=92, Evalue=5e-20,
Organism=Drosophila melanogaster, GI85726443, Length=159, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24656772, Length=154, Percent_Identity=34.4155844155844, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24656767, Length=193, Percent_Identity=31.6062176165803, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24656777, Length=163, Percent_Identity=32.5153374233129, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 20932; Mature: 20932

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIDRRMVVLGLGASLSGAMIASRVAQAENAAVSKSTAYRFSFPVPSGEPIRLADFAGKP
CCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEECCCCCC
VLVVNTASQCGYTPQYTGLQKLWSEFHERGLTIIAVPSNDFNQEPGVGGDIAELANKEYG
EEEEECHHHCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHCCCCCC
VTFPMTAKAVVTGSNAHPFYRWAAEARPKDTPRWNFHKYLVGRDGYIADVFASSVEPTDT
EECCCEEEEEEECCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCEEHHHHHCCCCCCHH
RVKTAIARMLAEG
HHHHHHHHHHHCC
>Mature Secondary Structure
MMIDRRMVVLGLGASLSGAMIASRVAQAENAAVSKSTAYRFSFPVPSGEPIRLADFAGKP
CCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEECCCCCC
VLVVNTASQCGYTPQYTGLQKLWSEFHERGLTIIAVPSNDFNQEPGVGGDIAELANKEYG
EEEEECHHHCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHCCCCCC
VTFPMTAKAVVTGSNAHPFYRWAAEARPKDTPRWNFHKYLVGRDGYIADVFASSVEPTDT
EECCCEEEEEEECCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCEEHHHHHCCCCCCHH
RVKTAIARMLAEG
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]