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The map label for this gene is clcB [H]

Identifier: 146339409

GI number: 146339409

Start: 2551783

End: 2553570

Strand: Direct

Name: clcB [H]

Synonym: BRADO2394

Alternate gene names: 146339409

Gene position: 2551783-2553570 (Clockwise)

Preceding gene: 146339408

Following gene: 146339410

Centisome position: 34.22

GC content: 67.06

Gene sequence:

>1788_bases
GTGCTCTCGACGCTGTCGCACATCATCGATCGCAAGGCCTCGAACCGGGTGGTCACGCGGCTGCGGGCGCTGCTGCGCAG
CAACGAGTTCTACCTGATACCGCTGGCGCTGGTGATCGGGGTCAGCACCGGCGCGATCGTGACGGTGATGAGCCTGATCG
CGCAATTCGCGCATGTGATCATTTACGGCATCCCGATCGACGTCCGGCTCAGTGCCAATGCCTGGGTCAACCCGGCAGTG
GCGCTGATCGCGCCGGCCTGCGGCGGTCTCGTCCTCGGACTGATGGAATGGTTGCGGCGGCGCTGGAAGATCGCGGCCGC
CGTCGACCCGGTCGAGGCCAACGCGCTGCGCGGCGGCCGGCTGTCGATGCGCGACAGCATCGTGGTGAGCAGCCAGACCC
TGGTCTCCAACGGCTCCGGCGCCTCGGTTGGCCTCGAGGCCGGCTACACTCAGATCGGCGCCGGCGTCGCTTCGCTGCTC
GGCCAGTATCTCACCCTTCGCCGCAACGACCTCAGGCTGATCGTCGGCTGCGGCGCCGCCGCCGCCATCGCCGCCGCCTT
CGGCGCGCCGATCACCGGCGCGTTCTATGCCTGTGAGCTGATCGTCGGCGTCTACTCGGTCGGCAGCGCAGCGCCTATTC
TGGCGGCATCCCTCGCGGGGGCGCTGACCTCGCAATATCTGACCGGCGCGCCGTATTCGCTCGAGATCCAGAAGGTCGGC
GCCGTCGGCTTCGAGCAATATATCGCGCTGTTCGTGCTGGCGCTGCTTGTGGCCTTCATCGGCATCGTGGTGATGCGCGC
TTCGCCTGCGGTGGAGCGGCTGTTCGTCCGTATCCCGGTCTGGATTCGTCCCATCATCGGCGGCCTCTGCGTGGGCGTTA
TGGCGATCGTGACGCCGCAGGTGCTGGCGGCCGGCCACGGCGCGATGCTGCTCGACCTTCATCGCGAGATGGCATTGGGC
ATCATCGCCACCATCATCGTGCTCAAGCTCGCCGCCTGCCTGATCTCGCTGGCCTCCGGCTTCCGCGGCGGCCTGTTCTT
CGCCTCGCTGTTCGTCGGCAGCCTGCTCGGCAAGCTGTTCGCCGGGTTGCTCGCTGTGGCCGGCCTGCCGCTGGCGCTCG
ACCCGCTGGTGGCGATGCTCACGGGCATGGCGACGCTCGGCGTCGCCATCGTTGGCGGGCCACTGACGATGTCCTTCCTG
GTGCTCGAGATGACCCGCAGCGTCGACGTCACGGCCGTCGTGCTCGGCGCCTGCATCGTCACCTCGGTGTGCGTGCGCGT
GCTGTTCGGGCACTCGTTCTCGACTTGGCGGCTGCATCTGCGTGGCGAGACCATCCGCAGCGCCAACGATGTGGGCTGGC
TGCGCAACCTCACGGTCGAGCGTCTGATGCGCTCCGACGTCGCCAAGGTGCCGACCACCACCTCGATCGCCGCCTGCCGC
CGCGAATTTGCATTGGGCACGCGCCAGGCTGTCGTGGTCGTCAACAACAGCGACGATTATTGTGGGCTGGTGTCCTTGCC
CGACCTTTTCTCGGGCGAGCTGGATTCCATCGCCGACGAGATTCAGGTGGTCGAACTCGCCAAATATTTCGAGGTCGCGC
TGTTGCCCGAAATGAACGTCAAGACGGCAATGCGGATCTTCGACGACACCGGCGCCGAGGAACTCGCCGTGCTGGAGTCG
GAGCACAGCCGCAAGGTGATCGGCTTCCTGACCGAGTCCTTCGCGCGCCGGCGCTATGTCGAGGAGATCGACCAGGCCAC
GCGCGGGGTGCTCGGCGCGCTGTCGTGA

Upstream 100 bases:

>100_bases
CAGTCAACCACGTTTCGACTGGAAAGGAATTCGCGCTTGTTCCGCTACTTGCGACAGGTTATTGCCACCGAGAGGCCTCC
TCGTAGAAGAAATGGCTCTC

Downstream 100 bases:

>100_bases
TCGCGTTGGTCTGCCGCCCCGCGTGATCTCGGAGCCGGGACGGGGGTAGGCTGCCGGATACGCGAGACGGATGAGGACCA
CATGACGAGACGGATCACGA

Product: CLC-type chloride channel protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MLSTLSHIIDRKASNRVVTRLRALLRSNEFYLIPLALVIGVSTGAIVTVMSLIAQFAHVIIYGIPIDVRLSANAWVNPAV
ALIAPACGGLVLGLMEWLRRRWKIAAAVDPVEANALRGGRLSMRDSIVVSSQTLVSNGSGASVGLEAGYTQIGAGVASLL
GQYLTLRRNDLRLIVGCGAAAAIAAAFGAPITGAFYACELIVGVYSVGSAAPILAASLAGALTSQYLTGAPYSLEIQKVG
AVGFEQYIALFVLALLVAFIGIVVMRASPAVERLFVRIPVWIRPIIGGLCVGVMAIVTPQVLAAGHGAMLLDLHREMALG
IIATIIVLKLAACLISLASGFRGGLFFASLFVGSLLGKLFAGLLAVAGLPLALDPLVAMLTGMATLGVAIVGGPLTMSFL
VLEMTRSVDVTAVVLGACIVTSVCVRVLFGHSFSTWRLHLRGETIRSANDVGWLRNLTVERLMRSDVAKVPTTTSIAACR
REFALGTRQAVVVVNNSDDYCGLVSLPDLFSGELDSIADEIQVVELAKYFEVALLPEMNVKTAMRIFDDTGAEELAVLES
EHSRKVIGFLTESFARRRYVEEIDQATRGVLGALS

Sequences:

>Translated_595_residues
MLSTLSHIIDRKASNRVVTRLRALLRSNEFYLIPLALVIGVSTGAIVTVMSLIAQFAHVIIYGIPIDVRLSANAWVNPAV
ALIAPACGGLVLGLMEWLRRRWKIAAAVDPVEANALRGGRLSMRDSIVVSSQTLVSNGSGASVGLEAGYTQIGAGVASLL
GQYLTLRRNDLRLIVGCGAAAAIAAAFGAPITGAFYACELIVGVYSVGSAAPILAASLAGALTSQYLTGAPYSLEIQKVG
AVGFEQYIALFVLALLVAFIGIVVMRASPAVERLFVRIPVWIRPIIGGLCVGVMAIVTPQVLAAGHGAMLLDLHREMALG
IIATIIVLKLAACLISLASGFRGGLFFASLFVGSLLGKLFAGLLAVAGLPLALDPLVAMLTGMATLGVAIVGGPLTMSFL
VLEMTRSVDVTAVVLGACIVTSVCVRVLFGHSFSTWRLHLRGETIRSANDVGWLRNLTVERLMRSDVAKVPTTTSIAACR
REFALGTRQAVVVVNNSDDYCGLVSLPDLFSGELDSIADEIQVVELAKYFEVALLPEMNVKTAMRIFDDTGAEELAVLES
EHSRKVIGFLTESFARRRYVEEIDQATRGVLGALS
>Mature_595_residues
MLSTLSHIIDRKASNRVVTRLRALLRSNEFYLIPLALVIGVSTGAIVTVMSLIAQFAHVIIYGIPIDVRLSANAWVNPAV
ALIAPACGGLVLGLMEWLRRRWKIAAAVDPVEANALRGGRLSMRDSIVVSSQTLVSNGSGASVGLEAGYTQIGAGVASLL
GQYLTLRRNDLRLIVGCGAAAAIAAAFGAPITGAFYACELIVGVYSVGSAAPILAASLAGALTSQYLTGAPYSLEIQKVG
AVGFEQYIALFVLALLVAFIGIVVMRASPAVERLFVRIPVWIRPIIGGLCVGVMAIVTPQVLAAGHGAMLLDLHREMALG
IIATIIVLKLAACLISLASGFRGGLFFASLFVGSLLGKLFAGLLAVAGLPLALDPLVAMLTGMATLGVAIVGGPLTMSFL
VLEMTRSVDVTAVVLGACIVTSVCVRVLFGHSFSTWRLHLRGETIRSANDVGWLRNLTVERLMRSDVAKVPTTTSIAACR
REFALGTRQAVVVVNNSDDYCGLVSLPDLFSGELDSIADEIQVVELAKYFEVALLPEMNVKTAMRIFDDTGAEELAVLES
EHSRKVIGFLTESFARRRYVEEIDQATRGVLGALS

Specific function: Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response [H]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081943, Length=353, Percent_Identity=30.5949008498584, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 62904; Mature: 62904

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSTLSHIIDRKASNRVVTRLRALLRSNEFYLIPLALVIGVSTGAIVTVMSLIAQFAHVI
CCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHCCCHHHHHHHHHHHHHHHHH
IYGIPIDVRLSANAWVNPAVALIAPACGGLVLGLMEWLRRRWKIAAAVDPVEANALRGGR
HEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCC
LSMRDSIVVSSQTLVSNGSGASVGLEAGYTQIGAGVASLLGQYLTLRRNDLRLIVGCGAA
CCCCCCEEEECHHHHCCCCCCCEEHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHH
AAIAAAFGAPITGAFYACELIVGVYSVGSAAPILAASLAGALTSQYLTGAPYSLEIQKVG
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHC
AVGFEQYIALFVLALLVAFIGIVVMRASPAVERLFVRIPVWIRPIIGGLCVGVMAIVTPQ
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAAGHGAMLLDLHREMALGIIATIIVLKLAACLISLASGFRGGLFFASLFVGSLLGKLF
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AGLLAVAGLPLALDPLVAMLTGMATLGVAIVGGPLTMSFLVLEMTRSVDVTAVVLGACIV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
TSVCVRVLFGHSFSTWRLHLRGETIRSANDVGWLRNLTVERLMRSDVAKVPTTTSIAACR
HHHHHHHHHCCCCCEEEEEEECCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
REFALGTRQAVVVVNNSDDYCGLVSLPDLFSGELDSIADEIQVVELAKYFEVALLPEMNV
HHHHCCCCEEEEEEECCCCCEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCH
KTAMRIFDDTGAEELAVLESEHSRKVIGFLTESFARRRYVEEIDQATRGVLGALS
HHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLSTLSHIIDRKASNRVVTRLRALLRSNEFYLIPLALVIGVSTGAIVTVMSLIAQFAHVI
CCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHCCCHHHHHHHHHHHHHHHHH
IYGIPIDVRLSANAWVNPAVALIAPACGGLVLGLMEWLRRRWKIAAAVDPVEANALRGGR
HEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCC
LSMRDSIVVSSQTLVSNGSGASVGLEAGYTQIGAGVASLLGQYLTLRRNDLRLIVGCGAA
CCCCCCEEEECHHHHCCCCCCCEEHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHH
AAIAAAFGAPITGAFYACELIVGVYSVGSAAPILAASLAGALTSQYLTGAPYSLEIQKVG
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHC
AVGFEQYIALFVLALLVAFIGIVVMRASPAVERLFVRIPVWIRPIIGGLCVGVMAIVTPQ
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAAGHGAMLLDLHREMALGIIATIIVLKLAACLISLASGFRGGLFFASLFVGSLLGKLF
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AGLLAVAGLPLALDPLVAMLTGMATLGVAIVGGPLTMSFLVLEMTRSVDVTAVVLGACIV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
TSVCVRVLFGHSFSTWRLHLRGETIRSANDVGWLRNLTVERLMRSDVAKVPTTTSIAACR
HHHHHHHHHCCCCCEEEEEEECCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
REFALGTRQAVVVVNNSDDYCGLVSLPDLFSGELDSIADEIQVVELAKYFEVALLPEMNV
HHHHCCCCEEEEEEECCCCCEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCH
KTAMRIFDDTGAEELAVLESEHSRKVIGFLTESFARRRYVEEIDQATRGVLGALS
HHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA