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The map label for this gene is 146339410

Identifier: 146339410

GI number: 146339410

Start: 2553652

End: 2554980

Strand: Direct

Name: 146339410

Synonym: BRADO2395

Alternate gene names: NA

Gene position: 2553652-2554980 (Clockwise)

Preceding gene: 146339409

Following gene: 146339411

Centisome position: 34.25

GC content: 69.53

Gene sequence:

>1329_bases
ATGACGAGACGGATCACGACGGCTGCCGCGGCCATCCTTGGCGTAGTGGTGACGGCCGCTGCCGCCGAGCCTGGTGTGCT
CAAGGGCAAGGACGCGTTCGGCGGCTGGCAGGGAGATGCGCCAGGCACTGTTCGCCTCATCCGTCCCGAGAACCTGCCGA
AGCCCGGAGCGACGGCGTCTGCCGCCAACGTCTCGCGCGTGGTGCAGCGGCCGGCCTCTGCTGTGCCCAAGGTGCCCGAC
GGCTTCAAGGTCGCGTTGTTCGCCGAGGGGCTGAGCGGGCCGCGCATCATCCGCACCGCGCCCAACGGCGACATCTTCGT
CGCCGAGACGCGCGCGGGCCGGGTCCGCGTGCTGCGGCCGAACGAGGATGGCAGCAAGGCCGAGGCGACGGAGATCTTCG
CCGATCGTCTCGGCCATCCCTTCGGCATCGCGTTCTACCCGATCGCCGATCCGCAATGGGTCTATGTCGCGAGCACCGAG
CGGGTGATGCGCTTTCCCTATCGCACGGGCGACATGAAGGCGTCCGGCGCGATGCAGGTCGTCGTGCCCGATCTCCCCGC
AGGCTATGGCCACTCCACCCGCGACATTGTCTTCACCAGAGATGGCCAGCGCATGCTGGTCTCGGTCGGCTCGGCCGGCA
ATGTCGGCGAAGCCCTGGGCGAGCCGGCCGGCGGCCTCGCCGCCTGGATCAAGGCGCATCCGCTCGGCGCCGCCTGGGGC
GGGGAGACCGATCGCGCCGGCGTGCTGGCGTTCGATCCCGAGGGCAAGAGCCGCAGCCTGTTCGCGAGCGGCATCCGCAA
CTGCGTCGGCCTCGCCATCCAGCCCGCGACCGGCATGCCATGGTGCTCGACCAATGAGCGCGACGGGCTCGGCGATGATC
TCGTCCCGGACTACGTCACGCGGGTGAAGGAGGGCGGCTTCTATGGCTGGCCCTGGTACTACATGGGCGACAACCCCGAT
CCGCGCCATGCCGGCGAGCGGCCGGATCTCAAGGGCCAGATCACGGTGCCCGACGTGCTGCTGCAGGCGCATTCCGCCTC
GCTGGGCCTGACCTTCTACGACGCCGACCTGTTTCCGCCGGAGTATCGCGGCGATGGCTTCGCGGCCGAGCACGGCTCGT
GGAACCGGTCGAAGCGCACCGGCTACAAGGTGATCCGCATCCGGCTGAAGGACGGCATGCCCACGGGCGAGTACGAGGAC
TTCGTCACCGGCTTCGTCGTCAATGATCGCGAAGTGTGGGGCCGGCCGGTCGGCGTCACCGTGGCGCGCGACGGCAGCCT
GCTGATCTCCGAGGACGGCAACGGCACGATCTGGCGCGTCAGCCGCTGA

Upstream 100 bases:

>100_bases
GCTCGGCGCGCTGTCGTGATCGCGTTGGTCTGCCGCCCCGCGTGATCTCGGAGCCGGGACGGGGGTAGGCTGCCGGATAC
GCGAGACGGATGAGGACCAC

Downstream 100 bases:

>100_bases
TGTGTGTCGTGCGGCGCAGGAACCTCGGCATCGCAACGCGGTTATGAGCGGGGTTGAACGCCGGAAGACTGCATGAACAT
CTTCGATCCGAAGGGACCGA

Product: putative L-sorbosone dehydrogenase

Products: NA

Alternate protein names: SNDH [H]

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MTRRITTAAAAILGVVVTAAAAEPGVLKGKDAFGGWQGDAPGTVRLIRPENLPKPGATASAANVSRVVQRPASAVPKVPD
GFKVALFAEGLSGPRIIRTAPNGDIFVAETRAGRVRVLRPNEDGSKAEATEIFADRLGHPFGIAFYPIADPQWVYVASTE
RVMRFPYRTGDMKASGAMQVVVPDLPAGYGHSTRDIVFTRDGQRMLVSVGSAGNVGEALGEPAGGLAAWIKAHPLGAAWG
GETDRAGVLAFDPEGKSRSLFASGIRNCVGLAIQPATGMPWCSTNERDGLGDDLVPDYVTRVKEGGFYGWPWYYMGDNPD
PRHAGERPDLKGQITVPDVLLQAHSASLGLTFYDADLFPPEYRGDGFAAEHGSWNRSKRTGYKVIRIRLKDGMPTGEYED
FVTGFVVNDREVWGRPVGVTVARDGSLLISEDGNGTIWRVSR

Sequences:

>Translated_442_residues
MTRRITTAAAAILGVVVTAAAAEPGVLKGKDAFGGWQGDAPGTVRLIRPENLPKPGATASAANVSRVVQRPASAVPKVPD
GFKVALFAEGLSGPRIIRTAPNGDIFVAETRAGRVRVLRPNEDGSKAEATEIFADRLGHPFGIAFYPIADPQWVYVASTE
RVMRFPYRTGDMKASGAMQVVVPDLPAGYGHSTRDIVFTRDGQRMLVSVGSAGNVGEALGEPAGGLAAWIKAHPLGAAWG
GETDRAGVLAFDPEGKSRSLFASGIRNCVGLAIQPATGMPWCSTNERDGLGDDLVPDYVTRVKEGGFYGWPWYYMGDNPD
PRHAGERPDLKGQITVPDVLLQAHSASLGLTFYDADLFPPEYRGDGFAAEHGSWNRSKRTGYKVIRIRLKDGMPTGEYED
FVTGFVVNDREVWGRPVGVTVARDGSLLISEDGNGTIWRVSR
>Mature_441_residues
TRRITTAAAAILGVVVTAAAAEPGVLKGKDAFGGWQGDAPGTVRLIRPENLPKPGATASAANVSRVVQRPASAVPKVPDG
FKVALFAEGLSGPRIIRTAPNGDIFVAETRAGRVRVLRPNEDGSKAEATEIFADRLGHPFGIAFYPIADPQWVYVASTER
VMRFPYRTGDMKASGAMQVVVPDLPAGYGHSTRDIVFTRDGQRMLVSVGSAGNVGEALGEPAGGLAAWIKAHPLGAAWGG
ETDRAGVLAFDPEGKSRSLFASGIRNCVGLAIQPATGMPWCSTNERDGLGDDLVPDYVTRVKEGGFYGWPWYYMGDNPDP
RHAGERPDLKGQITVPDVLLQAHSASLGLTFYDADLFPPEYRGDGFAAEHGSWNRSKRTGYKVIRIRLKDGMPTGEYEDF
VTGFVVNDREVWGRPVGVTVARDGSLLISEDGNGTIWRVSR

Specific function: Converts L-sorbosone into 2-keto-L-gulonic acid (2KGA) [H]

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.burgdorferi BB024 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 47335; Mature: 47204

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRITTAAAAILGVVVTAAAAEPGVLKGKDAFGGWQGDAPGTVRLIRPENLPKPGATAS
CCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCC
AANVSRVVQRPASAVPKVPDGFKVALFAEGLSGPRIIRTAPNGDIFVAETRAGRVRVLRP
HHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEECCCCEEEEECC
NEDGSKAEATEIFADRLGHPFGIAFYPIADPQWVYVASTERVMRFPYRTGDMKASGAMQV
CCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCEEEECCCCCCCCCCCCEEEE
VVPDLPAGYGHSTRDIVFTRDGQRMLVSVGSAGNVGEALGEPAGGLAAWIKAHPLGAAWG
EECCCCCCCCCCCCEEEEEECCCEEEEEECCCCCHHHHHCCCCCCCEEHEECCCCCCCCC
GETDRAGVLAFDPEGKSRSLFASGIRNCVGLAIQPATGMPWCSTNERDGLGDDLVPDYVT
CCCCCCCEEEECCCCCCCHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCCCCCCHHHHH
RVKEGGFYGWPWYYMGDNPDPRHAGERPDLKGQITVPDVLLQAHSASLGLTFYDADLFPP
HHHCCCEECCCEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCEEEEEEECCCCCC
EYRGDGFAAEHGSWNRSKRTGYKVIRIRLKDGMPTGEYEDFVTGFVVNDREVWGRPVGVT
CCCCCCEEECCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHEEEEEEECHHHCCCCEEEE
VARDGSLLISEDGNGTIWRVSR
EECCCCEEEEECCCCCEEEECC
>Mature Secondary Structure 
TRRITTAAAAILGVVVTAAAAEPGVLKGKDAFGGWQGDAPGTVRLIRPENLPKPGATAS
CCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCC
AANVSRVVQRPASAVPKVPDGFKVALFAEGLSGPRIIRTAPNGDIFVAETRAGRVRVLRP
HHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEECCCCEEEEECC
NEDGSKAEATEIFADRLGHPFGIAFYPIADPQWVYVASTERVMRFPYRTGDMKASGAMQV
CCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCEEEECCCCCCCCCCCCEEEE
VVPDLPAGYGHSTRDIVFTRDGQRMLVSVGSAGNVGEALGEPAGGLAAWIKAHPLGAAWG
EECCCCCCCCCCCCEEEEEECCCEEEEEECCCCCHHHHHCCCCCCCEEHEECCCCCCCCC
GETDRAGVLAFDPEGKSRSLFASGIRNCVGLAIQPATGMPWCSTNERDGLGDDLVPDYVT
CCCCCCCEEEECCCCCCCHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCCCCCCHHHHH
RVKEGGFYGWPWYYMGDNPDPRHAGERPDLKGQITVPDVLLQAHSASLGLTFYDADLFPP
HHHCCCEECCCEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCEEEEEEECCCCCC
EYRGDGFAAEHGSWNRSKRTGYKVIRIRLKDGMPTGEYEDFVTGFVVNDREVWGRPVGVT
CCCCCCEEECCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHEEEEEEECHHHCCCCEEEE
VARDGSLLISEDGNGTIWRVSR
EECCCCEEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7574579 [H]