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The map label for this gene is tctD [H]

Identifier: 146338490

GI number: 146338490

Start: 1507791

End: 1508456

Strand: Reverse

Name: tctD [H]

Synonym: BRADO1408

Alternate gene names: 146338490

Gene position: 1508456-1507791 (Counterclockwise)

Preceding gene: 146338494

Following gene: 146338489

Centisome position: 20.23

GC content: 67.87

Gene sequence:

>666_bases
TTGCGCATCCTGCTGGTGGAAGACACGCCCGAGATCGGCGCCGCCGTGACCAGCCGGTTCGAGCGGATCGGCTACGCCGT
CGACTGGGAGAAGGACGGTCGCACCGCGAGCGAGCTGATCGAGGTGCAGACCTATGACCTCATTGTGCTCGACGTAATGC
TGCCGAACATGGACGGCTTTGCCGTGCTCAAGCACTTGCGCAAGCGCGGCCTGCGCACCCCGGTGCTGGTGCTGACGGCG
CGCTCGGCGGTCGACGACCGGATCGGCGCGCTCGACCTCGGTGCCGACGACTATCTCATCAAACCGTTCGACTATCGCGA
GCTGGAGGCGCGAGCGCGCGCCCTACTCCGCCGCGCCGCCGGCCAATCCGACAATCTGCTGACATTGGGGCCGCTGGTGA
TCGACCGCGCCGGCCGGACCGCGAGCGTCGCCGGCCAGCCGCTCGACCTGACGCGGCGCGAGCTGACCGTGCTGGAGATC
CTCGCTGCACGCCCCGGGCGCTACGTCGCCAAAGAGGAACTGGTCGAGCAGCTGTTCAGCTTCGACCAGGATCCGAGCCC
GAACGCCGTCGAGCAGTTCATCGCGCGTCTCAGGCGCAAGCTGGCGGCCACGTCCGTCGAGATCAAGACCGAGCGCGGCC
TTGGCTATCAGCTCCACGCTTCGTGA

Upstream 100 bases:

>100_bases
TTGCAGTGCGAAATTTCGCCCGGTGCACTTCGGCGCCCTTGTGCGAAGTGATAGAGGAGGAGACTGACGCGAACCTGACT
CCGGGACTGAGACCACGACC

Downstream 100 bases:

>100_bases
GATCAAGACGTCGCTGCGCGCGCGGCTTCTGATCGCGATCGGCGCAATCCTGGCGGTCGGCGCGGTCGTGCTCAGTCTCG
CCGCCTGGCAATATGCGGCC

Product: OmpR family two component response transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MRILLVEDTPEIGAAVTSRFERIGYAVDWEKDGRTASELIEVQTYDLIVLDVMLPNMDGFAVLKHLRKRGLRTPVLVLTA
RSAVDDRIGALDLGADDYLIKPFDYRELEARARALLRRAAGQSDNLLTLGPLVIDRAGRTASVAGQPLDLTRRELTVLEI
LAARPGRYVAKEELVEQLFSFDQDPSPNAVEQFIARLRRKLAATSVEIKTERGLGYQLHAS

Sequences:

>Translated_221_residues
MRILLVEDTPEIGAAVTSRFERIGYAVDWEKDGRTASELIEVQTYDLIVLDVMLPNMDGFAVLKHLRKRGLRTPVLVLTA
RSAVDDRIGALDLGADDYLIKPFDYRELEARARALLRRAAGQSDNLLTLGPLVIDRAGRTASVAGQPLDLTRRELTVLEI
LAARPGRYVAKEELVEQLFSFDQDPSPNAVEQFIARLRRKLAATSVEIKTERGLGYQLHAS
>Mature_221_residues
MRILLVEDTPEIGAAVTSRFERIGYAVDWEKDGRTASELIEVQTYDLIVLDVMLPNMDGFAVLKHLRKRGLRTPVLVLTA
RSAVDDRIGALDLGADDYLIKPFDYRELEARARALLRRAAGQSDNLLTLGPLVIDRAGRTASVAGQPLDLTRRELTVLEI
LAARPGRYVAKEELVEQLFSFDQDPSPNAVEQFIARLRRKLAATSVEIKTERGLGYQLHAS

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=42.6605504587156, Blast_Score=180, Evalue=6e-47,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=39.3665158371041, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=39.6396396396396, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=34.8214285714286, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=32.5688073394495, Blast_Score=127, Evalue=4e-31,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=35.2941176470588, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=33.4821428571429, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=38.4955752212389, Blast_Score=113, Evalue=8e-27,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=33.4801762114537, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=31.0810810810811, Blast_Score=106, Evalue=9e-25,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=30.6666666666667, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1786911, Length=184, Percent_Identity=36.9565217391304, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=28.3842794759825, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=28.82096069869, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788550, Length=158, Percent_Identity=32.2784810126582, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=38.8888888888889, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=39.6039603960396, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=103, Percent_Identity=33.9805825242718, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790299, Length=117, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=31.3725490196078, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24640; Mature: 24640

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVEDTPEIGAAVTSRFERIGYAVDWEKDGRTASELIEVQTYDLIVLDVMLPNMDGF
CEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHEEEEEEECCCCCHH
AVLKHLRKRGLRTPVLVLTARSAVDDRIGALDLGADDYLIKPFDYRELEARARALLRRAA
HHHHHHHHCCCCCCEEEEEEHHHHHHHCCEEECCCCCCEECCCCHHHHHHHHHHHHHHHC
GQSDNLLTLGPLVIDRAGRTASVAGQPLDLTRRELTVLEILAARPGRYVAKEELVEQLFS
CCCCCEEEECHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
FDQDPSPNAVEQFIARLRRKLAATSVEIKTERGLGYQLHAS
CCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEECC
>Mature Secondary Structure
MRILLVEDTPEIGAAVTSRFERIGYAVDWEKDGRTASELIEVQTYDLIVLDVMLPNMDGF
CEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHEEEEEEECCCCCHH
AVLKHLRKRGLRTPVLVLTARSAVDDRIGALDLGADDYLIKPFDYRELEARARALLRRAA
HHHHHHHHCCCCCCEEEEEEHHHHHHHCCEEECCCCCCEECCCCHHHHHHHHHHHHHHHC
GQSDNLLTLGPLVIDRAGRTASVAGQPLDLTRRELTVLEILAARPGRYVAKEELVEQLFS
CCCCCEEEECHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
FDQDPSPNAVEQFIARLRRKLAATSVEIKTERGLGYQLHAS
CCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]