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The map label for this gene is rssA [H]

Identifier: 146338489

GI number: 146338489

Start: 1506410

End: 1507816

Strand: Reverse

Name: rssA [H]

Synonym: BRADO1407

Alternate gene names: 146338489

Gene position: 1507816-1506410 (Counterclockwise)

Preceding gene: 146338490

Following gene: 146338486

Centisome position: 20.22

GC content: 67.24

Gene sequence:

>1407_bases
TTGGCTATCAGCTCCACGCTTCGTGAGATCAAGACGTCGCTGCGCGCGCGGCTTCTGATCGCGATCGGCGCAATCCTGGC
GGTCGGCGCGGTCGTGCTCAGTCTCGCCGCCTGGCAATATGCGGCCACGGCGGCGCGCGATGCCTATGACAAGCTGCTCG
CCGGCGGCGCCGTGCAGGTCGCGGAGAACATCTACATGCAGGGCGGCGTGGTGACGCTCGATCCGCCGGCGGCGGCGTTC
GCAACCTTGTCGGCCTATGATCTCGTGTTCTACCGCGTCACCGATCCGCGCGGCGTCGTCGTCGCCGGCTATGACGATCT
CGCGATCCAGGCCCCCAAGAGCGCGCTGCGCGACGGCGTCGTGCTGCGTGATGGCGTCTACCGCGACCAGCCGGTGCGCA
TCGCCGCCGTCGCACGGCGCCTCGACGGCGCACCGGGCGAGGGCTGGAGCGAGATCGTGCTGGCGCAGACGGTGCGCGCG
CGCGACGCGCTGACCTGGGATCTCGCGTCCAAGGCGATCGGCCTGATCGCGGCGATGAGTCTGCTGGCGCTGGTCGCGAC
CGCACTGTGCCTGCGGCTGGTGTTCGCGCCGCTGACGCGGATCGAGGCCGAGATCGTCAAGCGCCGGCCTGATGATCTCA
GCCCGATCGCGATCACGCCGCCGCGCGAGGTCCGCGCATTGGTCGGCGCCATCGACGGCTTCATGCAGCGCCTGTCGGAG
CGGATTAAGCTGATGCAGCGCTTCATCGCCGACGCGACGCATCAGCTGCGGACGCCGCTGGCCGCGATCGATGCGGAGGT
GGAGTTGCTGAGCGGCCAGACCAGCGATCCGAAGACGCTCGATCGGTTGCGCGGTCGCATCTCGGACCTCGCCCGCCTCG
CCAGTCAGTTGCTGGATCATGCCATGATCCAGCACCGAGCACAGACGCCGCGCTTCGCGCCGACCGACATCAACGCGTTG
GCGAAATCGGTGTTGTCGCAGAGCGTCCCGCTGTCGCTGGACCGCGAAGTCTCCGTGAGTTTCGTGGACTCCGACGACGA
TGTCGTCGTCGCAGCCGATGCCATCAGCCTGCGCGAGGCACTCGCCAATCTGATCCACAACGCGCTGGCACATGGGGCGA
GGACGCGGCTGATGGTGAAGGTGGAGCGGACAGCGGAGAGTGTCGCGATCGTCGTCTGGGATGATGGACCGGGCATTCCT
GCAGACGCGCAGGCGGGACTGCTGGTGCCGTTCGAGAAGGGCGACGACTCGCATGGATCGGGGCTTGGGCTTGCGATCGC
TGTGGAGGTCGCACAAGCCCATGGCGGCCGCTTATGCTTCGACGGCGGAGCAGGTGATTTCAGCGTGAGGCTCGAGCTGC
CGATCAGCGACAGCGTAGCTGATCTGTCCCCTATCATATCCAAGTGA

Upstream 100 bases:

>100_bases
TTCGACCAGGATCCGAGCCCGAACGCCGTCGAGCAGTTCATCGCGCGTCTCAGGCGCAAGCTGGCGGCCACGTCCGTCGA
GATCAAGACCGAGCGCGGCC

Downstream 100 bases:

>100_bases
AGAAACGTCGAGATTAGACTCGAACTGCCGCTCCGATGCCGGTGCGCTCCCCTCCCCCTTGCGGGGAGGGTCGGGGGTGG
GGGTCCCCGAATGACGCTGA

Product: putative two-component system histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MAISSTLREIKTSLRARLLIAIGAILAVGAVVLSLAAWQYAATAARDAYDKLLAGGAVQVAENIYMQGGVVTLDPPAAAF
ATLSAYDLVFYRVTDPRGVVVAGYDDLAIQAPKSALRDGVVLRDGVYRDQPVRIAAVARRLDGAPGEGWSEIVLAQTVRA
RDALTWDLASKAIGLIAAMSLLALVATALCLRLVFAPLTRIEAEIVKRRPDDLSPIAITPPREVRALVGAIDGFMQRLSE
RIKLMQRFIADATHQLRTPLAAIDAEVELLSGQTSDPKTLDRLRGRISDLARLASQLLDHAMIQHRAQTPRFAPTDINAL
AKSVLSQSVPLSLDREVSVSFVDSDDDVVVAADAISLREALANLIHNALAHGARTRLMVKVERTAESVAIVVWDDGPGIP
ADAQAGLLVPFEKGDDSHGSGLGLAIAVEVAQAHGGRLCFDGGAGDFSVRLELPISDSVADLSPIISK

Sequences:

>Translated_468_residues
MAISSTLREIKTSLRARLLIAIGAILAVGAVVLSLAAWQYAATAARDAYDKLLAGGAVQVAENIYMQGGVVTLDPPAAAF
ATLSAYDLVFYRVTDPRGVVVAGYDDLAIQAPKSALRDGVVLRDGVYRDQPVRIAAVARRLDGAPGEGWSEIVLAQTVRA
RDALTWDLASKAIGLIAAMSLLALVATALCLRLVFAPLTRIEAEIVKRRPDDLSPIAITPPREVRALVGAIDGFMQRLSE
RIKLMQRFIADATHQLRTPLAAIDAEVELLSGQTSDPKTLDRLRGRISDLARLASQLLDHAMIQHRAQTPRFAPTDINAL
AKSVLSQSVPLSLDREVSVSFVDSDDDVVVAADAISLREALANLIHNALAHGARTRLMVKVERTAESVAIVVWDDGPGIP
ADAQAGLLVPFEKGDDSHGSGLGLAIAVEVAQAHGGRLCFDGGAGDFSVRLELPISDSVADLSPIISK
>Mature_467_residues
AISSTLREIKTSLRARLLIAIGAILAVGAVVLSLAAWQYAATAARDAYDKLLAGGAVQVAENIYMQGGVVTLDPPAAAFA
TLSAYDLVFYRVTDPRGVVVAGYDDLAIQAPKSALRDGVVLRDGVYRDQPVRIAAVARRLDGAPGEGWSEIVLAQTVRAR
DALTWDLASKAIGLIAAMSLLALVATALCLRLVFAPLTRIEAEIVKRRPDDLSPIAITPPREVRALVGAIDGFMQRLSER
IKLMQRFIADATHQLRTPLAAIDAEVELLSGQTSDPKTLDRLRGRISDLARLASQLLDHAMIQHRAQTPRFAPTDINALA
KSVLSQSVPLSLDREVSVSFVDSDDDVVVAADAISLREALANLIHNALAHGARTRLMVKVERTAESVAIVVWDDGPGIPA
DAQAGLLVPFEKGDDSHGSGLGLAIAVEVAQAHGGRLCFDGGAGDFSVRLELPISDSVADLSPIISK

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790551, Length=270, Percent_Identity=29.6296296296296, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI145693157, Length=223, Percent_Identity=28.2511210762332, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082128, Length=299, Percent_Identity=27.0903010033445, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789403, Length=454, Percent_Identity=24.4493392070485, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786783, Length=301, Percent_Identity=26.578073089701, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786912, Length=226, Percent_Identity=26.5486725663717, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786600, Length=211, Percent_Identity=27.0142180094787, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789808, Length=294, Percent_Identity=27.5510204081633, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=29.1304347826087, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790346, Length=225, Percent_Identity=27.1111111111111, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788393, Length=227, Percent_Identity=27.7533039647577, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1787374, Length=240, Percent_Identity=27.0833333333333, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790861, Length=254, Percent_Identity=27.5590551181102, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788279, Length=253, Percent_Identity=24.1106719367589, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790300, Length=217, Percent_Identity=29.0322580645161, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1790436, Length=230, Percent_Identity=26.0869565217391, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49706; Mature: 49575

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISSTLREIKTSLRARLLIAIGAILAVGAVVLSLAAWQYAATAARDAYDKLLAGGAVQV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AENIYMQGGVVTLDPPAAAFATLSAYDLVFYRVTDPRGVVVAGYDDLAIQAPKSALRDGV
HHHHHHCCCEEEECCCHHHHHHHHHEEEEEEEEECCCEEEEECCCCCEEECCHHHHHCCE
VLRDGVYRDQPVRIAAVARRLDGAPGEGWSEIVLAQTVRARDALTWDLASKAIGLIAAMS
EEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLALVATALCLRLVFAPLTRIEAEIVKRRPDDLSPIAITPPREVRALVGAIDGFMQRLSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHH
RIKLMQRFIADATHQLRTPLAAIDAEVELLSGQTSDPKTLDRLRGRISDLARLASQLLDH
HHHHHHHHHHHHHHHHHCCHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AMIQHRAQTPRFAPTDINALAKSVLSQSVPLSLDREVSVSFVDSDDDVVVAADAISLREA
HHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHH
LANLIHNALAHGARTRLMVKVERTAESVAIVVWDDGPGIPADAQAGLLVPFEKGDDSHGS
HHHHHHHHHHCCCHHEEEEEEECCCCEEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCC
GLGLAIAVEVAQAHGGRLCFDGGAGDFSVRLELPISDSVADLSPIISK
CCEEEEEEEEHHCCCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHCC
>Mature Secondary Structure 
AISSTLREIKTSLRARLLIAIGAILAVGAVVLSLAAWQYAATAARDAYDKLLAGGAVQV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AENIYMQGGVVTLDPPAAAFATLSAYDLVFYRVTDPRGVVVAGYDDLAIQAPKSALRDGV
HHHHHHCCCEEEECCCHHHHHHHHHEEEEEEEEECCCEEEEECCCCCEEECCHHHHHCCE
VLRDGVYRDQPVRIAAVARRLDGAPGEGWSEIVLAQTVRARDALTWDLASKAIGLIAAMS
EEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLALVATALCLRLVFAPLTRIEAEIVKRRPDDLSPIAITPPREVRALVGAIDGFMQRLSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHH
RIKLMQRFIADATHQLRTPLAAIDAEVELLSGQTSDPKTLDRLRGRISDLARLASQLLDH
HHHHHHHHHHHHHHHHHCCHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AMIQHRAQTPRFAPTDINALAKSVLSQSVPLSLDREVSVSFVDSDDDVVVAADAISLREA
HHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHH
LANLIHNALAHGARTRLMVKVERTAESVAIVVWDDGPGIPADAQAGLLVPFEKGDDSHGS
HHHHHHHHHHCCCHHEEEEEEECCCCEEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCC
GLGLAIAVEVAQAHGGRLCFDGGAGDFSVRLELPISDSVADLSPIISK
CCEEEEEEEEHHCCCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA