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The map label for this gene is ycbL [H]

Identifier: 146337644

GI number: 146337644

Start: 515679

End: 516347

Strand: Reverse

Name: ycbL [H]

Synonym: BRADO0510

Alternate gene names: 146337644

Gene position: 516347-515679 (Counterclockwise)

Preceding gene: 146337646

Following gene: 146337642

Centisome position: 6.92

GC content: 63.98

Gene sequence:

>669_bases
ATGAGCGAACAGAACCAGATCAAGGCGAAGGCCGGCGCAATGATCGTGCCCGTCACGCCATTCGAGCAGAACTGCACCAT
CCTGTGGTGCGAGGCCACGAAGAAGGCGATCGTGATCGATCCTGGCGGCGACGTGCCGAACATCCAGGCGGCGATCGCGC
AGGCCAACGTCACGGTGGAGAAGATCTGGCTGACCCATGGCCACATCGATCACGTCGGCGGCGCCGCGGATCTACGCGAT
GCACTGAAGGTGCCGATCGAGGGCCCTCACATCGCCGACAAGTACCTGCTCGACAACGTCGTCGAGAGTGGCAAGCGTTT
CGGCATCACGGGCGTGCGCGACGTCACGCCGGACCGCTGGCTGGAGGAGGGCGACACCGTCCAGATCGGCGAGCTCGTCT
TCGACATCCTGCATTGCCCCGGTCATTCGCCGGGCAGCGTCGTGTTCTTCAACAAGCAGATGCGCTTCGCCCATGTCGGC
GACGTCCTGTTCAACGGCTCGGTCGGCCGCACCGATCTGCCCGGCGGCAGCCATGAGACATTGATCAGCTCGATCAAGGA
CAAGCTGCTGCCGCTCGGCGACGACATCGGCTTCATCTGCGGCCACGGCGCCGGCTCGAGCTTCGGCCAGGAGCGGATGA
CGAACCCGTTCTTGACAGGGATGGCTTAG

Upstream 100 bases:

>100_bases
AGCCGGCAGGTTCACAAGCCCGGCCGTGCTCTTGGCATGAGGCCGCTACGAACGGACGTTTTTCGCTTGGCGCATTGCGA
AAAATCGGCATGCTGGCGCC

Downstream 100 bases:

>100_bases
TTGACGTCCGTCATTCCGGGGCAGCCCGCAGGGCTGAACCCGGAATCTCGAGATTCCCAGATGCGCAATCGCGCATCCGA
TGTCTGGTCCTTCGGACCAT

Product: metallo-hydrolase/oxidoreductase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MSEQNQIKAKAGAMIVPVTPFEQNCTILWCEATKKAIVIDPGGDVPNIQAAIAQANVTVEKIWLTHGHIDHVGGAADLRD
ALKVPIEGPHIADKYLLDNVVESGKRFGITGVRDVTPDRWLEEGDTVQIGELVFDILHCPGHSPGSVVFFNKQMRFAHVG
DVLFNGSVGRTDLPGGSHETLISSIKDKLLPLGDDIGFICGHGAGSSFGQERMTNPFLTGMA

Sequences:

>Translated_222_residues
MSEQNQIKAKAGAMIVPVTPFEQNCTILWCEATKKAIVIDPGGDVPNIQAAIAQANVTVEKIWLTHGHIDHVGGAADLRD
ALKVPIEGPHIADKYLLDNVVESGKRFGITGVRDVTPDRWLEEGDTVQIGELVFDILHCPGHSPGSVVFFNKQMRFAHVG
DVLFNGSVGRTDLPGGSHETLISSIKDKLLPLGDDIGFICGHGAGSSFGQERMTNPFLTGMA
>Mature_221_residues
SEQNQIKAKAGAMIVPVTPFEQNCTILWCEATKKAIVIDPGGDVPNIQAAIAQANVTVEKIWLTHGHIDHVGGAADLRDA
LKVPIEGPHIADKYLLDNVVESGKRFGITGVRDVTPDRWLEEGDTVQIGELVFDILHCPGHSPGSVVFFNKQMRFAHVGD
VLFNGSVGRTDLPGGSHETLISSIKDKLLPLGDDIGFICGHGAGSSFGQERMTNPFLTGMA

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=226, Percent_Identity=26.5486725663717, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1787158, Length=204, Percent_Identity=51.4705882352941, Blast_Score=230, Evalue=6e-62,
Organism=Caenorhabditis elegans, GI17538952, Length=199, Percent_Identity=27.6381909547739, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23818; Mature: 23687

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQNQIKAKAGAMIVPVTPFEQNCTILWCEATKKAIVIDPGGDVPNIQAAIAQANVTVE
CCCCHHHHHHCCEEEEECCCCCCCCEEEEEECCCCEEEECCCCCCCCHHHHHHHCCCEEE
KIWLTHGHIDHVGGAADLRDALKVPIEGPHIADKYLLDNVVESGKRFGITGVRDVTPDRW
EEEEECCCHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEECCCCCCCCCCHHH
LEEGDTVQIGELVFDILHCPGHSPGSVVFFNKQMRFAHVGDVLFNGSVGRTDLPGGSHET
HCCCCEEEHHHHHHHHHHCCCCCCCEEEEEECCCCEEECCCEEECCCCCCCCCCCCCHHH
LISSIKDKLLPLGDDIGFICGHGAGSSFGQERMTNPFLTGMA
HHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHCCCCHHCCCC
>Mature Secondary Structure 
SEQNQIKAKAGAMIVPVTPFEQNCTILWCEATKKAIVIDPGGDVPNIQAAIAQANVTVE
CCCHHHHHHCCEEEEECCCCCCCCEEEEEECCCCEEEECCCCCCCCHHHHHHHCCCEEE
KIWLTHGHIDHVGGAADLRDALKVPIEGPHIADKYLLDNVVESGKRFGITGVRDVTPDRW
EEEEECCCHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEECCCCCCCCCCHHH
LEEGDTVQIGELVFDILHCPGHSPGSVVFFNKQMRFAHVGDVLFNGSVGRTDLPGGSHET
HCCCCEEEHHHHHHHHHHCCCCCCCEEEEEECCCCEEECCCEEECCCCCCCCCCCCCHHH
LISSIKDKLLPLGDDIGFICGHGAGSSFGQERMTNPFLTGMA
HHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]