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The map label for this gene is ccmB [H]

Identifier: 146337537

GI number: 146337537

Start: 395225

End: 395893

Strand: Reverse

Name: ccmB [H]

Synonym: BRADO0391

Alternate gene names: 146337537

Gene position: 395893-395225 (Counterclockwise)

Preceding gene: 146337538

Following gene: 146337536

Centisome position: 5.31

GC content: 71.0

Gene sequence:

>669_bases
ATGACCGCCCTCGGTGCCCTCATCCGCCGCGACATCCGGATCGCGCTACGCATTGGCGGCGGTGCGCTGATTGGCGTGCT
GTTCTTCCTCACCGTGGTCGTGCTGATGCCGTTTGCCGTCGGCCCGGATCTCGCCCTGCTCACCCGCCTCGGCCCGGCGA
TCCTCTGGCTCGGCGCCCTGCTCGCCAGCCTGCTGACGCTCGACCGCCTGTTCACCGCGGACCACGAGGACGGCTCGCTC
GACCTGATCATCATGAGCCGGACGCCGCTGGAGTTCGCCTGCGCCGCCAAGGCGCTGGCGCACTGGCTGGCCGCCGGGCT
GCCGCTGGTGATCGCCACGCCCGTGCTCGGCCTGCTGCTGAACCTCGACGCCACCGCCACCGGCGCCGTCGCCCTGACCC
TGCTGGCCGGCACGCCGGCGCTGACCTTCATCGGCATGATCGGCGCAGCACTGGCGGTGACGATGTCCCGTGGCGGCCTG
CTGCTGGCCGTTTTGGTCCTGCCGCTGTCGATCCCGGTGCTGATCTTCGGCGTCGCGGCGTCGCAGGCGGCCATCGTCGG
CCCGCTGCCGTTCGGCGCGCCGTTCTCGATCCTCTGCGCCTTGTCGCTGGTCAGCTTCGTGATCGGCCCGTTCGCAGCCG
CAACCAGCCTGCGCAACGGCCTGGACTAA

Upstream 100 bases:

>100_bases
GACCCCCACCCCCAACCCCTCCCCGCAGGGGGGAGGGGAGCGCAGCGAGTTCGGAGCAGCAGCGTCGCTCCCAAGCATTT
CTCATCAGGGCTCTTTTCCA

Downstream 100 bases:

>100_bases
CGGAACACCGGCGGGGTTTGACCATGATCAACTCTTGCCGAGCTGTCCTGTGCTGATGGACTGTAAACGTTTCCGCCTTT
AACAAGGGCCTCATGTCGCT

Product: heme ABC transporter permease

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycW [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTALGALIRRDIRIALRIGGGALIGVLFFLTVVVLMPFAVGPDLALLTRLGPAILWLGALLASLLTLDRLFTADHEDGSL
DLIIMSRTPLEFACAAKALAHWLAAGLPLVIATPVLGLLLNLDATATGAVALTLLAGTPALTFIGMIGAALAVTMSRGGL
LLAVLVLPLSIPVLIFGVAASQAAIVGPLPFGAPFSILCALSLVSFVIGPFAAATSLRNGLD

Sequences:

>Translated_222_residues
MTALGALIRRDIRIALRIGGGALIGVLFFLTVVVLMPFAVGPDLALLTRLGPAILWLGALLASLLTLDRLFTADHEDGSL
DLIIMSRTPLEFACAAKALAHWLAAGLPLVIATPVLGLLLNLDATATGAVALTLLAGTPALTFIGMIGAALAVTMSRGGL
LLAVLVLPLSIPVLIFGVAASQAAIVGPLPFGAPFSILCALSLVSFVIGPFAAATSLRNGLD
>Mature_221_residues
TALGALIRRDIRIALRIGGGALIGVLFFLTVVVLMPFAVGPDLALLTRLGPAILWLGALLASLLTLDRLFTADHEDGSLD
LIIMSRTPLEFACAAKALAHWLAAGLPLVIATPVLGLLLNLDATATGAVALTLLAGTPALTFIGMIGAALAVTMSRGGLL
LAVLVLPLSIPVLIFGVAASQAAIVGPLPFGAPFSILCALSLVSFVIGPFAAATSLRNGLD

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=212, Percent_Identity=44.811320754717, Blast_Score=127, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 22591; Mature: 22459

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALGALIRRDIRIALRIGGGALIGVLFFLTVVVLMPFAVGPDLALLTRLGPAILWLGAL
CCHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LASLLTLDRLFTADHEDGSLDLIIMSRTPLEFACAAKALAHWLAAGLPLVIATPVLGLLL
HHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
NLDATATGAVALTLLAGTPALTFIGMIGAALAVTMSRGGLLLAVLVLPLSIPVLIFGVAA
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
SQAAIVGPLPFGAPFSILCALSLVSFVIGPFAAATSLRNGLD
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TALGALIRRDIRIALRIGGGALIGVLFFLTVVVLMPFAVGPDLALLTRLGPAILWLGAL
CHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LASLLTLDRLFTADHEDGSLDLIIMSRTPLEFACAAKALAHWLAAGLPLVIATPVLGLLL
HHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
NLDATATGAVALTLLAGTPALTFIGMIGAALAVTMSRGGLLLAVLVLPLSIPVLIFGVAA
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
SQAAIVGPLPFGAPFSILCALSLVSFVIGPFAAATSLRNGLD
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]